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Blog Profile / Fight Aging

Filed Under:Health / Aging
Posts on Regator:3828
Posts / Week:11.4
Archived Since:April 26, 2008

Blog Post Archive

A Review of What Can Be Done Today About Brain Aging

7 hours agoHealth / Aging : Fight Aging

Little can be done today to stem the tide of age-related degeneration, at least in comparison to the potential rejuvenation treatments of tomorrow. It remains the case that regular moderate exercise and calorie restriction have moreShow More Summary

More Investigation of the Choroid Plexus in Brain Aging

8 hours agoHealth / Aging : Fight Aging

A fair amount of research over the years has pointed to dysfunction of the choroid plexus as a contributing factor to degeneration in the brain. This structure generates and filters cerebrospinal fluid, and is thus its decline is a candidate...Show More Summary

A Better Understanding of the Mechanisms of ALT, Alternative Lengthening of Telomeres

18 hours agoHealth / Aging : Fight Aging

Telomeres cap the ends of chromosomes and shorten with each cell division, one part of the collection of mechanisms that limits the lifespan of somatic cells that make up the bulk of our tissues. Fresh cells with long telomeres are regularly...Show More Summary

Coming Around to the Idea of Radical Life Extension

yesterdayHealth / Aging : Fight Aging

One of the reasons that most people reject the idea of living longer through new medical technologies is that they believe, incorrectly, that it will result in being aged, frail, and in pain for longer. This is not the goal, and probably...Show More Summary

A Novel Type of Cellular Garbage in Aging

yesterdayHealth / Aging : Fight Aging

A variety of forms of cellular garbage accumulate with aging, and in some cases it is up for debate as to whether the garbage is a primary cause of aging or secondary effect of other damage that degrades cell maintenance. The origins...Show More Summary

SENS Research Foundation Newsletter, September 2014

3 days agoHealth / Aging : Fight Aging

The latest news from the SENS Research Foundation turned up in my inbox today. The Foundation is perhaps the only organization in the world today that is organizing and funding serious scientific work on prevention and reversal of aging. Show More Summary

How Does Tau Protein Accumulation Harm Brain Cells in Age-Related Neurodegenerative Conditions?

3 days agoHealth / Aging : Fight Aging

One of the discoveries of past years in Alzheimer's disease research is that the ?-amyloid accumulating between cells is less harmful to neurons than other associated proteins involved in the creation of that amyloid. Here is a paper...Show More Summary

Altered Myeloid Microglia Improve Alzheimer's Symptoms

4 days agoHealth / Aging : Fight Aging

Growing amounts of amyloid-? (A?) between cells forms one part of the pathology of Alzheimer's disease. This is a dynamic process, as much a matter of reduced clearance rates as increased production or simple accumulation: there areShow More Summary

A Summary View of Everything in Modern Longevity Science Except the Work that Really Matters

4 days agoHealth / Aging : Fight Aging

There are three classes of aging research, in order of decreasing size and funding: firstly the work that only investigates and catalogs aging, with no attempt to intervene; secondly work on ways to slow aging through metabolic and genetic...Show More Summary

Nanogel Scaffolding and Cellular Heart Patches

5 days agoHealth / Aging : Fight Aging

One approach to scaffolding for tissue engineering is to deliver a dissolving material along with transplanted cells that provides just enough support for those cells to get them past the point of generating their own extracellular matrix scaffold to replace the artificial material. Show More Summary

Demonstrating Decellularized Heart Valves

5 days agoHealth / Aging : Fight Aging

Decellularization of donor organs and tissue sections has been demonstrated in laboratory animals and trialed in humans for some years now. It is clearly an improvement over straight organ donation in that it greatly reduces transplant...Show More Summary

The Glenn Research Consortium Continues to Grow

5 days agoHealth / Aging : Fight Aging

For some years now the Glenn Foundation for Medical Research has been establishing a network of labs to work on aging and longevity, seeding them with grants of a few million dollars apiece. The research they carry out is fairly mainstream,...Show More Summary

Using Songbird Brains to Investigate Regenerative Neurogenesis

6 days agoHealth / Aging : Fight Aging

An unusual characteristic of some songbirds is that parts of their brain vary greatly in size between seasons. Researchers believe that finding the exact mechanisms that trigger this atrophy and regrowth of neurons will lead to waysShow More Summary

Proposing Combination Gene Therapy to Slow Aging

6 days agoHealth / Aging : Fight Aging

There are all sorts of longevity-associated genetic manipulations either demonstrated or postulated to produce benefits in mice. Why not try them all at once to see what happens? If you think that slowing aging through alteration ofShow More Summary

Further Altering GHRKO Mice to Determine the Necessary Mechanisms of their Longevity

6 days agoHealth / Aging : Fight Aging

Growth hormone receptor knockout (GHRKO) mice are one of the longest-lived genetically engineered mouse lineages produced to date, and this is one of the few interventions that can slow aging and extend life to a greater degree in mice than is possible via the practice of calorie restriction. Show More Summary

Testing a Bioartificial Liver

last weekHealth / Aging : Fight Aging

Artificial organs capable of performing some of the functions of the real thing don't have to look or be structured in the same way as our evolved organs. They just have to work. Efforts to develop artificial organs have benefited from...Show More Summary

A New Approach to Targeting Metastasis in Cancer

last weekHealth / Aging : Fight Aging

Most cancers kill through metastasis, the spread of cancerous cells throughout the body to seed numerous secondary tumors. Without this process cancer would be much less threatening and more amenable to treatment. Thus numerous research...Show More Summary

Strive to Live or Strive to Die, But at Least Do Something, Show a Little Agency in the Matter

last weekHealth / Aging : Fight Aging

There will always be naysayers when it comes to the prospects for enhanced health and longevity: people who claim that they want to die younger than they might, that they don't want to do anything about the aging process, and that they'll be content with a lifespan that is the same as their parents and their peers. Show More Summary

Telomerase has an Off Switch

last weekHealth / Aging : Fight Aging

Telomerase is the enzyme responsible for lengthening telomeres, caps of repeating DNA sequences at the end of chromosomes. Telomere length acts as a clock of sorts, as telomeres shorten with each cell division. This is one part of aShow More Summary

Insight into Peter Thiel's Support of Longevity Science

last weekHealth / Aging : Fight Aging

Philanthropist Peter Thiel is one of the patrons of the SENS Research Foundation, perhaps the only organization in the world at this point that is coordinating and funding serious efforts to build rejuvenation treatments. Thiel recently...Show More Summary

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