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Blog Profile / Fight Aging


URL :http://www.fightaging.org
Filed Under:Health / Aging
Posts on Regator:3879
Posts / Week:11.4
Archived Since:April 26, 2008

Blog Post Archive

Recent Metastasis Research

13 hours agoHealth / Aging : Fight Aging

Most cancers kill through metastasis. It isn't the initial malignant tumor but rather the spread of its cells throughout the body to seed more growths that outpaces today's medical toolkit. Absent metastasis, most cancers would be far...Show More Summary

Achieving Immortality by Ending Aging

yesterdayHealth / Aging : Fight Aging

Some people do seem to like to jump straight to talking about immortality as soon as the topic of extending human life comes up. Immortality here is meant in the sense of complete resistance to aging through medical technology capable of repairing the cellular and molecular damage that causes degenerative aging and all its symptoms and conditions. Show More Summary

Dementia as a Consequence of Many Small, Unnoticed Strokes

yesterdayHealth / Aging : Fight Aging

Dementia can result from age-related damage to the white matter in the brain, known as leukoaraiosis or white matter hyperintensities. Here researchers look at the source of this damage: Approximately 50 per cent of older individuals have evident white matter damage on their medical imaging scans. Show More Summary

The Role of Immune Cells in Enhanced Regeneration of Organs

yesterdayHealth / Aging : Fight Aging

Immune cells play an important role in regeneration, though this is yet another aspect of the immune system as a whole that is understood in outline but the all-important details remain a big blank space in the middle of the map. The...Show More Summary

Primary Age-Related Tauopathy

2 days agoHealth / Aging : Fight Aging

Alzheimer's disease is the name given to the end state of rising amyloid levels in the brain: it is the stage at which the patient has a lot of amyloid and is severely impacted by it. But we will all suffer increased levels of amyloid to some degree, and we will all be negatively affected by it to some degree. Show More Summary

Tissue Engineering of Small Stomachs for Research

2 days agoHealth / Aging : Fight Aging

The first stage of success in tissue engineering of any specific organ is to produce small sections of tissue that are close enough to the real thing to be used in research. Given a methodology to reliably produce these tissue sections...Show More Summary

Impact of Lifelong Cytomegalovirus Infection on Aging

2 days agoHealth / Aging : Fight Aging

I don't normally point out funding press materials, preferring to focus on the other end of the research process, but this one, drawn to my attention by the Healthspan Campaign newsletter, contains a good overview of the current state of knowledge regarding the persistent herpesvirus called cytomegalovirus (CMV) and its role in immune aging. Show More Summary

Cross-Links Stiffen the Extracellular Matrix With Age

3 days agoHealth / Aging : Fight Aging

One of the root causes of degenerative aging is the accumulation of sugary metabolic wastes known as advanced glycation end-products that are in some cases very hard to for our evolved biochemistry to break down. Some types can form cross-links, gluing together important proteins such as those making up the supporting extracellular matrix scaffold. Show More Summary

mTOR Signaling and Menopause

3 days agoHealth / Aging : Fight Aging

Researchers are digging in to some of the proximate mechanisms that lead to menopause, and making some progress by the looks of it. This is a good example of the general approach to aging taken by the research community: start at the...Show More Summary

A Profound Lack of Ambition When it Comes to Longer Lives

3 days agoHealth / Aging : Fight Aging

We live in an age of rapidly advancing biotechnology, and research communities are on the verge of developing actual, real, working rejuvenation treatments. Given the funding there are lines of research under way today that might take the ills of aging and turn them back. Show More Summary

Challenges in Using Old Tissue and Cells in Treatments

4 days agoHealth / Aging : Fight Aging

Cell therapies and tissue engineering benefit from being able to use a patient's own cells as a starting point. If the patient is old, as is the case for most potential uses of regenerative medicine, cells are tissues are damaged and dysfunctional. Show More Summary

Boosting FoxO1 to Treat Pulmonary Hypertension

4 days agoHealth / Aging : Fight Aging

Researchers here uncover an interesting role for one of the forkhead box (FOX) proteins, and the potential basis for a treatment for pulmonary hypertension: An estimated 100 million people worldwide suffer from pulmonary hypertension. Show More Summary

The Most-Cited Near Future Directions in Aging Research

4 days agoHealth / Aging : Fight Aging

Citations in an academic paper have some similarities to links in the web, or at least in the case where those links are a result of human choice and consideration. Considered in the abstract, a citation is a vote of attention rather than an opinion on the contents of the cited paper. Show More Summary

An Interesting View of Mitochondrial Damage and Disease

5 days agoHealth / Aging : Fight Aging

Mitochondria are the bacteria-like power plants of the cell, thousands to each cell, and each mitochondrion bearing its own DNA separate from that in the cell nucleus. Damage to this DNA is important in aging, and in a variety of diseases. Show More Summary

Decellularization in Blood Vessel Transplants

5 days agoHealth / Aging : Fight Aging

Given a donor blood vessel, researchers can strip it of its cells to leave just the extracellular matrix structure. This can then be repopulated with a patient's own cells, making it possible to transplant the blood vessel without risk of rejection. Show More Summary

Attractive Modern Websites for the Cryonics Providers

5 days agoHealth / Aging : Fight Aging

Cryonics involves the low-temperature preservation of the recently deceased, and as an industry it has been around for some decades. Using modern techniques and if the preservation is accomplished with speed, this can result in a good preservation of the fine structure of the brain, and thus of the data that makes up the mind. Show More Summary

Screening for Stress Resistance Mutations in Mice

5 days agoHealth / Aging : Fight Aging

The open access paper quoted below provides some insight into increasing sophistication of the work involved in identifying longevity-related genes and proteins in mammals. Many of these have been discovered over the past twenty years, leading to numerous ways to alter the operation of metabolism in order to slow aging and thus extend healthy life. Show More Summary

Towards the Production of New Photoreceptor Cells In Situ

5 days agoHealth / Aging : Fight Aging

The evolution of cell therapies will most likely be towards treatments that alter cell type and behavior in place, drawing from the existing pool of cells and changing them to suit the needs of the patient. Given sufficient control over...Show More Summary

The Prospects for a MicroRNA-Based Biomarker of Aging

5 days agoHealth / Aging : Fight Aging

The development of accurate and cheap biomarkers of biological age is an important goal for the research community. The issue at hand is this: short of sitting back and waiting for years or decades, how should one test a supposed rejuvenation...Show More Summary

The Other Activities of Telomerase

5 days agoHealth / Aging : Fight Aging

Telomerase extends telomeres, the protective ends of chromosomes. A portion is lost with each cell division, and this mechanism forms part of a clock regulating the replicative life span of ordinary cells. Stem cells maintain long telomeres and when active work to introduce into tissues a continual supply of new daughter cells with long telomeres. Show More Summary

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