Blog Profile / Fight Aging


URL :http://www.fightaging.org
Filed Under:Health / Aging
Posts on Regator:3922
Posts / Week:9.6
Archived Since:April 26, 2008

Blog Post Archive

Arguing that Progeria Mechanisms are Significant Enough in Normal Aging to Be Worth Addressing

11 hours agoHealth / Aging : Fight Aging

Today I'll point out a very long post that argues we should pay more attention to the mechanisms of Hutchinson-Gilford progeria syndrome (HGPS, or simply progeria) in normal aging. Progeria is one of a small number of rare conditions in which patients have the appearance of accelerated aging. Show More Summary

Tuning Macrophages in Cancer Immunotherapy

22 hours agoHealth / Aging : Fight Aging

Immunotherapy is a broad category, and covers many very different strategies for tackling cancer and other conditions by engineering immune cells or adjusting the behavior of the immune system as a whole. In this case, researchers have...Show More Summary

On Building Measures to Link Aging and Disease

22 hours agoHealth / Aging : Fight Aging

In this popular science article on the relationship between aging and age-related disease, a researcher discusses one of a number of approaches to producing a biomarker of aging, a sensitive measure of the degree to which an individual is impacted by the cell and tissue damage of aging. Show More Summary

21st Century Medicine Wins the Small Mammal Brain Preservation Prize

yesterdayHealth / Aging : Fight Aging

The folk at 21st Century Medicine have been working, largely unheralded, for years with the aim of improving the technologies used in cryopreservation of tissue. The goals are twofold: firstly to make cryonics a much more reliable and...Show More Summary

In Search of the Genetics of Longevity in Sea Urchins

yesterdayHealth / Aging : Fight Aging

Comparative biology is an important tool in aging research, as the analysis of similar species with widely divergent life spans can in theory point out the more important mechanisms of aging. The more similar the species the better,Show More Summary

Protecting Osteoblasts to Enhance Bone Mass and Strength

yesterdayHealth / Aging : Fight Aging

Bone is constantly remodeled at the small scale, created by cells called osteoblasts and destroyed by cells called osteoclasts. One of the proximate causes of osteoporosis, age-related loss of bone mass and strength, is a growing imbalance between these two cell populations. Show More Summary

Is the Present Human Life Span Enough?

2 days agoHealth / Aging : Fight Aging

Is the present human life span enough? This was the topic for a recent debate, wherein Aubrey de Grey of the SENS Research Foundation and Brian Kennedy of the Buck Institute were matched against Ian Ground of Newcastle University and Paul Root Wolpe of the Emory Center for Ethics. Show More Summary

Aging Hair Follicles Change to Become Skin

2 days agoHealth / Aging : Fight Aging

An interesting mechanism that appears to contribute to age-related hair loss was recently identified. It is unusual in that cells of one tissue structure are changing to cells of another as a result of age-related damage: ScientistsShow More Summary

How Do Stem Cell Transplants Produce Heart Regeneration?

2 days agoHealth / Aging : Fight Aging

Stem cell transplants spur greater regeneration in an injured heart that would normally be the case, and so far it appears to be the case that this is a matter of signaling that changes the behavior of native cells rather than the transplanted stem cells integrating with native tissue and generating new cells. Show More Summary

The SENS Rejuvenation Biotechnology Companies

5 days agoHealth / Aging : Fight Aging

After the laboratory, the next stage of development in rejuvenation therapies involves the founding of biotechnology startups. There is no clear-cut point at which research stops being non-profit in the laboratory and starts being for-profit in a venture-funded startup. Show More Summary

Cytomegalovirus Associated with Cognitive Decline in Aging

6 days agoHealth / Aging : Fight Aging

Researchers here find an association in an older study population between the presence of cytomegalovirus (CMV) - and other common herpesviruses - and the observed degree of cognitive decline. A good deal of evidence from past yearsShow More Summary

Towards Reversible Cryopreservation of Organs

6 days agoHealth / Aging : Fight Aging

There is a fairly strong connection between the small cryonics industry, focused on preserving the human mind following death in order to offer a chance at renewed life in a more technologically capable future, and present efforts to reversibly cryopreserve organs. Show More Summary

Enhanced Proteasomal Activity Restores Declining Self-Renewal in Aging Neural Stem Cells

6 days agoHealth / Aging : Fight Aging

The proteasome is a type of cellular structure tasked with breaking down damaged and unwanted proteins, its activities one part of a broad variety of maintenance mechanisms found inside the living cell. Today I'll point out the latest...Show More Summary

Iron Oxide Nanoparticles Reduce Oxidative Stress in Flies

last weekHealth / Aging : Fight Aging

Researchers have found that iron oxide nanoparticles can act in similar ways to cellular antioxidants such as catalase, soaking up oxidative molecules and reducing oxidative stress and consequent damage. To the degree that this helps...Show More Summary

Clearing Mitochondria Reverses Some Aspects of Cellular Senescence

last weekHealth / Aging : Fight Aging

Cellular senescence is a response to damage or environmental factors such as toxins, wounds, and oxidative stress. It removes cells from the processes of growth and replication, and probably serves, at least initially, as a way to reduce cancer risk. Show More Summary

25% Median Life Extension in Mice via Senescent Cell Clearance, Unity Biotechnology Founded to Develop Therapies

last weekHealth / Aging : Fight Aging

With today's news, it certainly seems that senescent cell clearance has come of age as an approach to treating aging and age-related conditions. Some of the leading folk in the cellular senescence research community today published the results from a very encouraging life span study, extending life in mice via a method of removing senescent cells. Show More Summary

Ampakine Prevents Loss of Dendrites in the Aging Rat Brain

last weekHealth / Aging : Fight Aging

The research community is very interested in loss of neural plasticity in the brain over the course of aging, a slowing of the introduction and integration of new neurons, and diminished pace of change in the connections between nerve cells. Show More Summary

On Developing a Stem Cell Therapy for Parkinson's Disease

last weekHealth / Aging : Fight Aging

This is an interesting short interview with a researcher working on aspects of a stem cell therapy for Parkinson's disease, with unusual results from animal studies in that the transplanted cells survive for a long time. In most first...Show More Summary

Recent Research on Muscles, Stem Cells, and Aging

last weekHealth / Aging : Fight Aging

Today I thought I'd point out a few recent papers and publicity materials on muscle aging. A large chunk of the research into stem cell aging and changes in cell metabolism with aging focus on muscle tissue. In part this is a feedback loop: the better understood models and types of cell are found in or associated with muscle tissue. Show More Summary

Proposing a Role for Acetylation in the Damage of Aging

last weekHealth / Aging : Fight Aging

Researchers here investigate fruit flies in search of age-related changes in the cellular processes of metabolism that occur in mid-life, early signs of degeneration and damage accumulation. They find that an increase in acetylationShow More Summary

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