Blog Profile / Fight Aging

Filed Under:Health / Aging
Posts on Regator:3451
Posts / Week:9.2
Archived Since:April 26, 2008

Blog Post Archive

Greater Incremental Damage to Brain Tissue Means a Greater Risk of Stroke and Death

9 hours agoHealth / Aging : Fight Aging

It shouldn't be too surprising to find that people with greater levels of minor brain damage are at greater risk of stroke and death, as noted by these researchers. Blood vessel integrity deteriorates with age, and as a result, many tiny areas of damage accumulate in the brain where small blood vessels suffer breakage. Show More Summary

Reassessing Smooth Muscle Cells in Atherosclerosis

10 hours agoHealth / Aging : Fight Aging

Over the last few years researchers have gathered data that suggests smooth muscle cells have a more important role in the later stages of atherosclerosis than previously suspected. This new result adds to the evidence: Until now, doctors...Show More Summary

More on Beta-2 Microglobulin Blood Levels and Aging, Resulting From Parabiosis Research

21 hours agoHealth / Aging : Fight Aging

Over the past couple of years, researchers have been involved in cataloging differences in signaling molecules in the blood when comparing old and young mice. This is an outgrowth of heterochronic parabiosis studies, in which an old and a young individual have their circulatory systems joined and the results observed. Show More Summary

Spurring Regrowth of Axons in Damaged Nerves

yesterdayHealth / Aging : Fight Aging

Axons extend from nerve cells, grouped in bundles to form nerves, with the longest axons running for a meter or more. When severed they tend not to regrow, a limitation that researchers are trying to work around. Here is one of a number...Show More Summary

SkQ1 Improves Impaired Skin Healing in Old Mice

yesterdayHealth / Aging : Fight Aging

Targeting antioxidants to the mitochondria inside cells has been shown to produce enough of a benefit to build therapies for a number of conditions, with better outcomes than standard antioxidant treatments. Researchers developing mitochondrially...Show More Summary

Inflammation is Still Poorly Understood in Comparison to Its Importance in Aging

3 days agoHealth / Aging : Fight Aging

Many researchers investigate inflammation, but like everything involving the immune system it is a very complex collection of processes, yet to be fully understood, and especially in the role it plays in degenerative aging. The greater...Show More Summary

Prions Involved in Long Term Memory Maintenance

4 days agoHealth / Aging : Fight Aging

If verified by other laboratories, this seems like a meaningful step forward in understanding the physical structure of memory. A greater knowledge of the biological basis for memory storage has important applications in many fields,...Show More Summary

A Report on the Second International Symposium on the Genetics of Aging and Life History

4 days agoHealth / Aging : Fight Aging

The number of scientific conferences covering the molecular biology of aging seems to be growing. Here is a recently published report from a conference held last year, for example: Aging is a fundamental problem that the world is currently facing. Show More Summary

Recent Papers on Energy Metabolism and Longevity

4 days agoHealth / Aging : Fight Aging

Here I'll point out a couple of papers on the topic of energy, metabolism, and natural variations in longevity. One of the many ways of looking at the operation of metabolism is from the point of view of energy consumption and expenditure:...Show More Summary

Stem Cells Age as Well

5 days agoHealth / Aging : Fight Aging

Today I thought I'd point out an interesting post from the Buck Institute team on the topic of stem cell aging. The good news here is that the characteristic age-related decline of stem cell function is an issue that the research community has to engage with on the way to developing effective treatments based on their work. Show More Summary

So: At What Age Do You Want to Become Diseased and Die?

5 days agoHealth / Aging : Fight Aging

Here are a few thoughts on the need for advocacy in longevity science from Rejuvenaction: People don't think that ageing is a disease because they're used to thinking that it's just a stage of life. They will start to finally acceptShow More Summary

A Rare Replication of a Human Longevity-Associated Gene Variant in Different Study Populations

5 days agoHealth / Aging : Fight Aging

It isn't often at all that researchers find an association between longevity and genetic variants in humans that holds up in different study populations. This is quite the contrast with shorter-lived species such as mice, where significant effects on longevity via genetic variants are near commonplace. Show More Summary

Cellular Senescence and Parkinson's Disease

6 days agoHealth / Aging : Fight Aging

The Buck Institute here provides a popular science look at links between cellular senescence and the development of Parkinson's disease. The proximate cause of the symptoms of Parkinson's is the diminishing numbers and function of a small collection of dopamine generating neurons in the brain. Show More Summary

The Latest Glenn Foundation Funding for Aging Research

6 days agoHealth / Aging : Fight Aging

In past years the Glenn Foundation for Medical Research has reinforced the mainstream of the aging research community with grants of a few million dollars apiece to establish or expand laboratories in many major universities and research centers. Show More Summary

Naked Mole Rats Retain Neural Plasticity Across a Life Span

6 days agoHealth / Aging : Fight Aging

Two of the many topics of interest found in the study of longevity are (a) the long-lived naked mole rat and (b) the processes by which the mammalian brain generates new neurons and connections to maintain itself. Today I'll point out...Show More Summary

Population Life Expectancy Inversely Correlated with Childhood Autoimmune Disease Incidence

last weekHealth / Aging : Fight Aging

A researcher here runs the numbers to demonstrate an inverse correlation between autoimmune disease incidence and life expectancy. It is interesting to speculate on the mechanisms here, which are probably not going to turn out to beShow More Summary

The Prospects for Stem Cells to Treat Chronic Wounds

last weekHealth / Aging : Fight Aging

Based on the evidence to date, stem cell transplants could be used to treat chronic, non-healing wounds that occur in older patients, though work to be accomplished in order to achieve this goal. Here is an open access review paper on...Show More Summary

Investigations of the INDY Gene Illustrate that "Very Slow" is the Default Speed of Aging Research

last weekHealth / Aging : Fight Aging

Here I point out a recent review on the topic of INDY gene manipulations and consequent increased longevity via altered metabolic processes. Given just how long ago this gene was discovered, and how similar at a high level the research...Show More Summary

An Early Attempt to Work Around Immunosenescence

last weekHealth / Aging : Fight Aging

Researchers have recently demonstrated a partial restoration of immune response in aged mice using a combination of existing Toll-like receptor agonists. This might be seen as a first step on the road to ways to reverse those aspects of immune system failure with age that depend more on misconfiguration rather than cellular damage. Show More Summary

Are Mitochondrial Mutations Really All That Important?

last weekHealth / Aging : Fight Aging

Prompted by attention given to a recent study claiming to cast doubt on the primary role of damaged mitochondria in aging, here is a lengthy and detailed article from the SENS Research Foundation on what is known of mitochondrial DNA damage and aging. Show More Summary

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