Blog Profile / Fight Aging

Filed Under:Health / Aging
Posts on Regator:3370
Posts / Week:9.1
Archived Since:April 26, 2008

Blog Post Archive

Diving Deeper into the Biochemistry of Muscle Aging

6 hours agoHealth / Aging : Fight Aging

If there is one sweeping generality to be made about cellular biochemistry, it is that everything is connected to everything else. No mechanism operates in isolation, and many areas of interest to aging research that have been studied point by point over the past few decades are all different aspects of the same larger system. Show More Summary

Inching Towards Treatments that Manipulate Heat Shock Protein Activity

18 hours agoHealth / Aging : Fight Aging

Heat shock proteins such as HSP70 are molecular chaperones involved in cellular housekeeping processes that clear out damaged or misfolded proteins. Their activity increases in response to heat, toxins, and various other forms of cellular...Show More Summary

Cellular Senescence and Stem Cell Aging

19 hours agoHealth / Aging : Fight Aging

In recent years, researchers have provided evidence to suggest that cellular senescence mechanisms are partly involved in the decline of stem cell activity in aging. It is an open question as to how this interacts with other signaling mechanisms also recently shown to influence the suppression of stem cell tissue maintenance. Show More Summary

Why Seek to Classify Aging as a Disease?

yesterdayHealth / Aging : Fight Aging

There is a growing determination in some portions of the aging research community to obtain a formal classification of aging as a disease. This means different things to different people, and there are numerous independent regulatory or classification bodies involved in defining and declaring disease. Show More Summary

Horizons: Extending Lives, Defying Mortality

yesterdayHealth / Aging : Fight Aging

Here is a link to the presentation page for a recent BBC program on initiatives aiming to give us control over aging and death, with video clips on cryonics and SENS rejuvenation research: We are in an era of disruptive technologies and innovation. Show More Summary

Another Example of Induced Pluripotency Reversing Mitochondrial Damage in Aging

yesterdayHealth / Aging : Fight Aging

In the past researchers have shown that reprogramming adult cells to create induced pluripotent stem cells sweeps away some specific forms of damage observed in old cells. In particular it seems to clean up damaged mitochondria, which is of considerable interest given the role of mitochondrial DNA damage in aging. Show More Summary

A Collection of Recent Mitochondrial Research

2 days agoHealth / Aging : Fight Aging

Mitochondria are the power plants of the cell, a herd of cell components evolved from symbiotic bacteria that are responsible for generating energy supplies to power cellular processes, among other tasks. Mitochondria are important in...Show More Summary

Male Offspring in Long-Lived Families are Less Fat

2 days agoHealth / Aging : Fight Aging

The amount of visceral fat carried by individuals, just like number of calories consumed, has a strong influence on natural variations in health and longevity. More visceral fat is a bad thing, producing chronic inflammation and other less well understood disruptions of metabolism. Show More Summary

Brain Preservation Foundation Prize Update

2 days agoHealth / Aging : Fight Aging

The Brain Preservation Foundation aims at advancing and validating the state of the art for preserving the fine structure of the human brain, containing the data of the mind. This is a goal of great value for the cryonics industry, and for the possible plastination industry that might arise to be its competitor. Show More Summary

A Few New Fight Aging! Fundraising Posters

3 days agoHealth / Aging : Fight Aging

We are nearing the first phase of this year's Fight Aging! fundraiser in support of the rejuvenation research programs carried out at the SENS Research Foundation. We are on the cusp of important progress in medical science, balanced...Show More Summary

Neural Stem Cell Transplant Treats Parkinson's in Rats

3 days agoHealth / Aging : Fight Aging

The proximate cause of the most visible symptoms of Parkinson's disease is the progressive loss of a small but vital population of dopamine-generating neurons. This loss happens to everyone, but for a variety of underlying reasons, not all of which are clear at this time, people with Parkinson's experience a more rapid loss of these cells. Show More Summary

Linking Mitochondrial DNA Damage and Glaucoma

3 days agoHealth / Aging : Fight Aging

Damage to mitochondrial DNA is a consequence of the normal operation of cellular processes, and is one of the contributing causes of degenerative aging. It acts through a convoluted chain of circumstances to generate a population of malfunctioning cells that export harmful reactive molecules into surrounding tissue. Show More Summary

Discussing Science and Aging: Aubrey de Grey and Cynthia Kenyon at NPR

6 days agoHealth / Aging : Fight Aging

NPR recently ran a show interviewing a number of people who have given TED talks relating to aging, among them Aubrey de Grey, cofounder of the SENS Research Foundation and coordinator of rejuvenation research programs, and Cynthia Kenyon,...Show More Summary

GABA Neuron Transplant Enhances Neural Plasticity in Mice

6 days agoHealth / Aging : Fight Aging

Neural plasticity, the ability of the brain to generate new neurons and reshape its pathways, declines with age. Finding ways to temporarily reverse this decline and induce a more youthful state of plasticity may prove helpful in treating...Show More Summary

Trials of Cell Therapies for Heart Regeneration

6 days agoHealth / Aging : Fight Aging

Stem cell therapies to repair heart damage were one of the first to become widely available via medical tourism, and have been underway in earnest for more than a decade now. There is evidence from their use that benefits can be attained for patients. Show More Summary

On Social Media and Advocacy for Radical Life Extension

last weekHealth / Aging : Fight Aging

Changing the world is an activity built atop a foundation of persuasion and relationships, whether is a matter of creating entirely new technology or ensuring the widespread use of existing technologies. It always moves more slowly than...Show More Summary

Cryonics is Still in Search of Better Approaches to End of Life Management

last weekHealth / Aging : Fight Aging

Cryonics is the industry and collection of technologies associated with low-temperature preservation of an individual upon death, necessarily carried out as soon as possible so as to prevent tissue damage in the brain. It is connected to research and development in forms of organ preservation associated with transplant medicine. Show More Summary

A Trial of Immunotherapy to Treat Multiple Myeloma

last weekHealth / Aging : Fight Aging

Any proposed first generation rejuvenation toolkit of future decades must include a robust approach to cancer therapy, at the very least offering reliable detection methods and cures even if not providing outright prevention. An important...Show More Summary

Parabiosis Research Identifies ?-catenin as a Target to Rejuvenate Bone Healing

last weekHealth / Aging : Fight Aging

Heterochronic parabiosis has become a growing line of research these past few years. It involves connecting the circulatory systems of two individuals, such as two laboratory mice, of different ages. Researchers have shown that the old...Show More Summary

Continued Investigations of Very Small Embryonic-Like Stem Cells in Adult Tissues

last weekHealth / Aging : Fight Aging

It is important in the development of the present and the next generation of stem cell therapies to have cheap, reliable access to patient-specific pluripotent stem cells on demand. These are the basic starting point for generating therapeutic cells of a specific type, and only pluripotent cells have the capacity to create cells of any type. Show More Summary

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