Blog Profile / Fight Aging


URL :http://www.fightaging.org
Filed Under:Health / Aging
Posts on Regator:4225
Posts / Week:9.9
Archived Since:April 26, 2008

Blog Post Archive

If I Were Going to Raise a Venture Fund, I'd Earmark 10% of Capital for Creating Startups By Funding Research that is Close to Completion

yesterdayHealth / Aging : Fight Aging

I should preface this short discussion by saying that I'm scarcely cut out to be raising a venture capital fund to target investments in SENS rejuvenation research companies and other useful ventures likely to help produce effective treatments for aging - ways to extend healthy life and defeat age-related disease. Show More Summary

The Biochemistry of Mammalian Hibernation as a Possible Basis for Therapies

yesterdayHealth / Aging : Fight Aging

Researchers are attempting to understand the biochemistry of limb and organ regeneration, exceptional cancer resistance, and hibernation in a number of species in order to see whether they can form the basis for therapies or enhancements in humans. Show More Summary

Exploring the Mechanisms of Age-Related Slowing of Visual Perception

yesterdayHealth / Aging : Fight Aging

Cognitive decline with aging is a patchwork of scores of progressive failures in different systems in the brain, all proceeding at their own pace. The research noted here is a good example of the way in which researchers try to pickShow More Summary

Rejuvenation Biotechnology 2016 will be Held at the Buck Institute in California

2 days agoHealth / Aging : Fight Aging

Rejuvenation Biotechnology 2016 is the latest in a series of conferences hosted by the SENS Research Foundation, focused on bringing together industry and academia to pave the way for the advent of first generation rejuvenation therapies. Show More Summary

Diabetes Greatly Increases Risk of Heart Attack

2 days agoHealth / Aging : Fight Aging

Diabetes of any variety is a damaging distortion of normal metabolism. Once in progress, it causes further harm on an ongoing basis. The type 2 diabetes most often seen in older people is a lifestyle condition: the vast majority of cases...Show More Summary

Mitofusin 2 in the Development of Sarcopenia

2 days agoHealth / Aging : Fight Aging

Sarcopenia is the name given to progressive age-related loss of muscle mass and strength. Here one possible contributing cause of the condition is explored, reduced levels of a protein involved in the quality control of mitochondria, which may allow damaged mitochondria to accumulate more readily. Show More Summary

Crowdfunding Longevity Science: an Interview with Keith Comito of Lifespan.io

3 days agoHealth / Aging : Fight Aging

Keith Comito leads the volunteers of the non-profit Life Extension Advocacy Foundation (LEAF) and the crowdfunding initiative Lifespan.io, a site I'm sure you've seen at least in passing by now. The LEAF crew have put in a lot of effort to help make fundraisers for rejuvenation research projects a success both last year and this year. Show More Summary

Chimeric Antigen Receptor Cancer Therapies Can Now Target Solid Tumors

3 days agoHealth / Aging : Fight Aging

If the research community is to win in the fight to cure cancer, and win soon enough to matter for all of us, then the focus must be on technology platforms that can be easily and cheaply adapted to many different types of cancer. The...Show More Summary

7-ketocholesterol Accumulation Speeds Calcification of Blood Vessels

3 days agoHealth / Aging : Fight Aging

Researchers here link vascular calcification in aging with an accumulation of one of a number of related forms of undesirable metabolic waste. One of the root causes of degenerative aging is this accumulation of hardy forms of metabolic waste that our biochemistry either finds hard to break down, or simply cannot break down. Show More Summary

Recent Research on Exercise, Aging, and Age-Related Disease

4 days agoHealth / Aging : Fight Aging

Quite a lot of research on exercise in the context of aging and age-related disease has been published in the past few months. More than usual, I think - not just a case of noticing because it is on my mind. Research moves in waves and cycles, just like all other human endeavors. Show More Summary

Another Possible Cancer Suppression Mechanism in Naked Mole Rats

4 days agoHealth / Aging : Fight Aging

Besides living for nine times longer than other, similarly sized rodent species, naked mole rats are also highly resistant to cancer, to the point at which only a handful of cases have ever been observed. The scientific community is seeking the roots of this cancer resistance to see if the mechanisms involved can form the basis for human therapies. Show More Summary

Investigating CD38 and NAD in Aging

4 days agoHealth / Aging : Fight Aging

Of late, there has been a growing interest in exploring mechanisms related to nicotinamide adenine dinucleotide (NAD) and the way in which their operation changes over the course of aging. This research has grown out of the last decade...Show More Summary

A So Far Weak Approach to Stimulating Autophagy to Slow Aging

5 days agoHealth / Aging : Fight Aging

The research materials for today offer one example of numerous parallel efforts to find a mechanism and drug candidate that can stimulate autophagy and thereby modestly slow the progression of aging. It is too early to say whether this...Show More Summary

Suggesting that Higher Levels of IGF-1 Might Slow Atherosclerosis Progression

5 days agoHealth / Aging : Fight Aging

Researchers have found that a reduced level of insulin-like growth factor 1 (IGF-1) in mice accelerates the progression of atherosclerosis, one of the more dangerous of age-related cardiovascular issues. Atherosclerosis involves theShow More Summary

In Search of Early, Asymptomatic Stages of Alzheimer's Disease

5 days agoHealth / Aging : Fight Aging

Many signs of age-related disease start as early as the 30s, damage that is asymptomatic and minimal, but nonetheless exactly the same type of dysfunction that will later, when present to a much greater degree, cause age-related disease, frailty, and death. Show More Summary

Fight Aging! Newsletter, June 20th 2016

6 days agoHealth / Aging : Fight Aging

FIGHT AGING! NEWSLETTER June 20th 2016 Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent...Show More Summary

To What Degree is Alzheimer's a Lifestyle Disease?

last weekHealth / Aging : Fight Aging

Type 2 diabetes is the archetypal lifestyle disease, a metabolic dysfunction run out of control to the point at which it disrupts the crucial mechanisms of insulin metabolism. Diabetes isn't accelerated aging, but it has many of the same consequences when viewed from the high level: more damage, more disease, higher mortality. Show More Summary

Stem Cells from Young Mice Heal Stomach Ulcers in Old Mice

last weekHealth / Aging : Fight Aging

When it comes to the question of whether young stem cells and a young tissue environment are necessary for the success of stem cell therapies, there is evidence to support all of the possible answers. It is a confusing picture at the moment, and it is very possible that the answer varies by cell type. Show More Summary

Progress in Tissue Engineered Bone, Matching Natural Bone Structure

last weekHealth / Aging : Fight Aging

Researchers have announced progress in the production of larger sections of bone for transplantation. Once transplanted, the new bone serves as a template to provoke further regeneration to match the structure of the natural bone that is replaced. Show More Summary

Replacing Neural Stem Cells in the Aging Hippocampus

last weekHealth / Aging : Fight Aging

Today I'll point out progress towards an as yet unrealized category of stem cell treatments involving the wholesale replacement of entire stem cell populations and their niches, to remove age-related damage and sustain tissue maintenance for the long term. Show More Summary

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