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Blog Profile / Fight Aging


URL :http://www.fightaging.org
Filed Under:Health / Aging
Posts on Regator:3923
Posts / Week:11.4
Archived Since:April 26, 2008

Blog Post Archive

Not Everyone Likes Mitochondrial DNA Damage as a Theory of Aging

3 hours agoHealth / Aging : Fight Aging

There are factions within the research community who argue against mitochondrial DNA damage as an important cause of aging. That said, I think I could pick any present hypothesis on the biochemistry of aging and find a faction whose members don't think much of it. Show More Summary

Initial Evidence for Glycogen Buildup in the Brain to Contribute to Aging

15 hours agoHealth / Aging : Fight Aging

This research suggests another type of metabolic waste should be added to those already known to contribute to degenerative aging. Given where the researchers presently stand, one logical next step might be to run mouse life span studies...Show More Summary

Lysosomal Dysfunction in Atherosclerosis

15 hours agoHealth / Aging : Fight Aging

Atherosclerosis is the build up of fatty plaques known as atheromas in blood vessel walls, leading to death or injury when blood vessels suffer structural failure or part of a plaque breaks loose to block a blood vessel elsewhere. Plaques...Show More Summary

Experimentation in Regenerative Reprogramming

yesterdayHealth / Aging : Fight Aging

Salamanders and zebrafish are among the species that can regenerate limbs and even large portions of vital organs after injury, and the regrown portions of their anatomy are just the same as the original. We mammals cannot do this: we can manage fingernails, occasionally fingertips at a very early age, and portions of the liver, but that is about it. Show More Summary

Investigating Nail Stem Cells

yesterdayHealth / Aging : Fight Aging

Nails are one of the few parts of the human body that can regenerate completely after loss in adults. So why not dig deeper into the biology of the stem cells involved? Perhaps it will teach us something more about why only a few types of mammalian tissue are capable of such complete regeneration. Show More Summary

Restoring Function to Old Pancreatic Islets

yesterdayHealth / Aging : Fight Aging

Researchers here transplant pancreatic islets from old to young mice and see restored function. They conclude that replacing the microvasculature that supplies blood to the tissue is the important change in this process, but I suspect...Show More Summary

Why Do We Advocate for Rejuvenation Research?

4 days agoHealth / Aging : Fight Aging

Yesterday, I had occasion to spend six hours or so in the emergency room of a medical center largely focused on treating serious conditions that are most prevalent in old people. A part of that experience by necessity involved listening to the comings, goings, and conversations of those present. Show More Summary

Lamin-B and Immunosenescence

4 days agoHealth / Aging : Fight Aging

The aging of the immune system isn't just a matter of damage, it is also inherent in the structure of a limited number of immune cells over time becoming ever more devoted to remembering threats rather than fighting them. As this research...Show More Summary

More Investigations of Calorie Restriction in Long-Lived Mice

4 days agoHealth / Aging : Fight Aging

Calorie restriction extends healthy life in mice, and so does removing or blocking the activity of growth hormone through genetic engineering. The reasons for enhanced longevity in both of these cases are well studied but still far from...Show More Summary

The Role of 3-D Printing in the Future of Medicine

5 days agoHealth / Aging : Fight Aging

3-D printing is a tool that has blossomed given the cheap computing resources to control it. It has long been possible to print three-dimensional structures in a variety of mediums, but efficient automation makes it cheaper to do this reliably and repeatedly, and also allows for the accurate manufacture of objects with very small scale features. Show More Summary

Delivering Stem Cell Factor into Damaged Heart Tissue

5 days agoHealth / Aging : Fight Aging

In the years ahead stem cell medicine will most likely transform into a field largely based on manipulating existing cell populations in situ in the body rather than generating cells outside the body for transplantation. In many types...Show More Summary

Suppressing PERK Improves Memory in Mice

5 days agoHealth / Aging : Fight Aging

There is a fair amount of work taking place these days on ways to manipulate the efficiency of memory processes: The brain's process of formulating memory is linked to the synthesis of proteins; high rates of protein production willShow More Summary

"We should not regard aging as a fact of life."

6 days agoHealth / Aging : Fight Aging

It is not correct to view aging as set in stone, an immutable part of the human condition. Degenerative aging is just another medical condition, an unpleasant one at that, caused by biochemical processes in the body that are just as open to discovery, cataloging, and intervention as those of any disorder. Show More Summary

Increasing Interest in DNA Methylation in Aging

6 days agoHealth / Aging : Fight Aging

Epigenetic mechanisms such as DNA methylation alter the pace at which specific proteins are manufactured. Epigenetic patterns are constantly in flux in our cells, changing in response to circumstances, the most interesting of which is the accumulation of cellular and molecular damage that causes aging. Show More Summary

A Discussion of Modest Goals in Treating Aging

6 days agoHealth / Aging : Fight Aging

Many researchers involved in longevity science initiatives have very modest goals. They are looking into how to alter metabolism to modestly slow the progression of aging, which is an enormously complex task and the research community is presently barely at the outset of obtaining a sufficient understanding to proceed effectively. Show More Summary

Regenerative Medicine and the Future of Healthy Longevity

6 days agoHealth / Aging : Fight Aging

One of the many possible future banners for applied longevity science is to call these treatments capable of extending healthy life span simply "regenerative medicine." In past years, regenerative medicine has referred to the outputShow More Summary

Calorie Restriction and Age-Related Gene Expression Changes in the Brain

6 days agoHealth / Aging : Fight Aging

The practice of calorie restriction with optimal nutrition, a lowered calorie intake while maintaining necessary dietary micronutrient levels, slows near all measures of aging in laboratory animals such as mice. The human studies ofShow More Summary

New Theorizing on Teleomere Length and Gene Regulation

6 days agoHealth / Aging : Fight Aging

Telomeres are caps of repeated DNA sequences at the ends of chromosomes. They shorten with each cell division, one part of a limiting mechanism for the number of times that somatic cells can replicate. Average telomere length in tissues...Show More Summary

Recent Investigations into the Mechanisms of Atherosclerosis

6 days agoHealth / Aging : Fight Aging

Atherosclerosis is a particularly unpleasant age-related condition not because it causes great suffering along the way but because it is comparatively invisible right up until the point at which it kills you suddenly. In atherosclerosis...Show More Summary

An Interesting Presentation on Aging Research

last weekHealth / Aging : Fight Aging

There are a number of people, researchers and advocates, in the longevity science community who have a good understanding of present research and knowledge, but who then build on that understanding to assemble what look to me to be completely the wrong conclusions about how best to proceed towards extending healthy life spans. Show More Summary

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