Blog Profile / Fight Aging


URL :http://www.fightaging.org
Filed Under:Health / Aging
Posts on Regator:3481
Posts / Week:9.2
Archived Since:April 26, 2008

Blog Post Archive

DRACO Illustrates the Poor Funding Situation for Radical Departures from the Existing Status Quo

yesterdayHealth / Aging : Fight Aging

DRACO, double-stranded RNA activated caspase oligomerizer, is a broadly applicable antiviral technology that has been under development at a slow pace for quite some time now. You might recall some publicity back in 2011, for example, but that marked the results of years of earlier work. Show More Summary

The Organoid Stage of the Tissue Engineering Revolution

yesterdayHealth / Aging : Fight Aging

The first stage for commercially useful tissue engineering is testing and further research, and that is actually well underway. Tissue sections for test and research purposes don't have to be large, and therefore the big problem of how to generate suitable blood vessel networks doesn't have to be solved yet. Show More Summary

Slowing Aging By Restricting Cryptic Transcription

yesterdayHealth / Aging : Fight Aging

Researchers have demonstrated slower aging in yeast by increasing H3K36 methylation, which has the effect of restricting certain forms of transcription, the first step in the process of gene expression whereby proteins are generated from their genetic blueprints. Show More Summary

The Struggle to Find Truth from a Position of Ignorance

2 days agoHealth / Aging : Fight Aging

Today I stumbled over a popular press article on the topic of longevity science, in which a fair amount of attention is given to Aubrey de Grey and the SENS Research Foundation vision for rejuvenation biotechnology. Like most such articles...Show More Summary

Targeting an Improvement in Protein Quality Control

2 days agoHealth / Aging : Fight Aging

A range of research efforts aim at finding ways to improve or enhance the activity of cellular maintenance mechanisms involved in ensuring quality control. Proteins are the building blocks of cell machinery but constantly become damaged or misfolded, which can then cause harm through incorrect function. Show More Summary

Supercentenarian Research Study

2 days agoHealth / Aging : Fight Aging

A number of ongoing research programs aim to collect more data on the biochemistry and genetics of the oldest of old people, and here is an example of one of them. I don't believe that these efforts contribute greatly towards building...Show More Summary

An Update on Spurring Heart Regeneration via PIM-1

3 days agoHealth / Aging : Fight Aging

A group of US researchers have demonstrated the potential to induce greater regeneration in heart tissue through overexpression of PIM-1. This is one of many varied approaches to generating greater repair and maintenance of tissues presently...Show More Summary

Towards Better Cryoprotectants, With an Eye on Thawing

3 days agoHealth / Aging : Fight Aging

Below find an interesting discussion of one research program aimed at producing a better class of cryoprotectant that enables tissue thawing without damage. The organ storage and cryonics industries have many of the same technical goals:...Show More Summary

Suggesting the Correlation Between Intelligence and Longevity is Mostly Genetic

3 days agoHealth / Aging : Fight Aging

Researchers building on twin study data are suggesting that the well-known correlation between greater intelligence and a little additional longevity is mostly genetic in nature, not a matter of more intelligent people making betterShow More Summary

The Wealthy are Just Like the Rest of Us in that Many Want to Do Good in the World

4 days agoHealth / Aging : Fight Aging

The public echo chamber is often crowded by class warfare sentiments, and they are rarely absent from any discussion of progress in medicine. The green-eyed monster of jealousy dons its best suit and those without power denounce those who have more of it because of their greater wealth. Show More Summary

More Salivary Gland Engineering

4 days agoHealth / Aging : Fight Aging

Here is recent news of another team working to engineer salivary gland tissue, one of many parts of the body typically given little thought until it stops working. This team doesn't seem to be as close to a functional end result as the...Show More Summary

Transthyretin Amyloidosis is More Prevalent than Thought

4 days agoHealth / Aging : Fight Aging

Evidence suggests that transthyretin (TTR) amyloidosis, also known as senile systemic amyloidosis, is the condition that kills the oldest people, those who have survived every other aspect of aging to reach ages of 110 and greater. Here,...Show More Summary

The Failing Immune System and Its Role in Pulmonary Disease

5 days agoHealth / Aging : Fight Aging

In the paper quoted below, researchers review the links between immune system dysfunction in aging and pulmonary diseases - diseases of the lungs, ranging from infections to fibrosis. This is just one of many classes of medical condition that are much more serious and frequent in the elderly. Show More Summary

Altering Metabolism to Slow or Override Aspects of Aging

5 days agoHealth / Aging : Fight Aging

Below find linked a popular science article on some of the strands of research that aim at safely altering the operation of cellular metabolism to either (a) gently slow aging by reducing the pace at which underlying cell and tissue damage accumulates or (b) override some of the reactions to cellular damage that cause declines in tissue maintenance. Show More Summary

Proposing a Novel Method to Sabotage Cancer Cells

5 days agoHealth / Aging : Fight Aging

Some types of cancer produce cells that are not as picky as ordinary, correctly functioning cells in the nucleosides they are willing to incorporate into their DNA during repair and replication. Researchers here propose that by introducing...Show More Summary

Immune Profiling the Contribution of Cytomegalovirus to Aging

last weekHealth / Aging : Fight Aging

Today I thought I'd point out an interesting and very readable open access paper on immune system aging and the contribution of cytomegalovirus to that process. The authors outline the generation of a large set of data on immune aging,...Show More Summary

Thoughts on the Funding Situation in Aging Research

last weekHealth / Aging : Fight Aging

Given the potential for producing effective treatments in near all areas of medicine brought about by the ongoing revolution in biotechnology, a growing number of people are coming to see that the present established systems of funding, both public and private, are essentially broken. Show More Summary

Arguing that Heat Shock Response Decline is Programmed

last weekHealth / Aging : Fight Aging

Researchers here present a fairly compelling case that the characteristic decline in the protective heat shock response with age is an evolved program. Compelling but not airtight: one could still argue that the rapid transition from...Show More Summary

Lanosterol versus Cataracts: Promising Initial Results

last weekHealth / Aging : Fight Aging

In the research noted here, scientists have identified a potential treatment for cataracts based on the details of a rare human mutation that causes cataracts to form in young children. These patients lack lanosterol, and for reasons not yet fully understood that causes cataract formation in the lens of the eye. Show More Summary

More on the Work of Researchers at the Buck Institute

last weekHealth / Aging : Fight Aging

This is the third in a recent series of local news articles on the work of the Buck Institute for Aging Research in California. Sadly very little of that work is relevant to the SENS vision of rejuvenation biotechnology, targeted repair of the damage that causes aging with the ultimate goal of entirely preventing degeneration and disease. Show More Summary

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