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Blog Profile / Fight Aging


URL :http://www.fightaging.org
Filed Under:Health / Aging
Posts on Regator:3859
Posts / Week:11.4
Archived Since:April 26, 2008

Blog Post Archive

Resetting Tissue GHK Levels to Provide Benefits to the Old

last weekHealth / Aging : Fight Aging

The aging research community might be divided into two camps. The much larger camp sees aging as a process of damage accumulation and reactions to that damage. There is a lot of argument over which forms of damage are more importantShow More Summary

Aging: Humanity Faces a Major Problem

last weekHealth / Aging : Fight Aging

The cost of aging is enormous, far greater than any other single cause of pain, suffering, and death. Approximately two thirds of all deaths are due to aging and its consequences: more than 100,000 lives are lost to aging each and every day. Show More Summary

Obesity Accelerates Aging of the Human Liver

last weekHealth / Aging : Fight Aging

Comparatively recently researchers have developed a potential measure of biological age using patterns of DNA methylation, a collection of epigenetic alterations that are in some cases fairly characteristic with age. It makes sense that...Show More Summary

Fundraising Update: $6,600 So Far, and $50,000 the Goal

last weekHealth / Aging : Fight Aging

On October 1st we kicked off this year's grassroots matching fundraiser in support of SENS Research Foundation programs. Earlier this year a group of us raised a $100,000 matching fund to encourage donations: each $1 donated to the SENS Research Foundation before the end of the year draws an additional $2 from the fund. Show More Summary

Discussing the Path to a Tissue Engineered Liver

last weekHealth / Aging : Fight Aging

An interesting interview with a tissue engineer can be found at the Methuselah Foundation blog. It covers one view of the path from today's research to the clinical availability of complete engineered livers constructed to order, among...Show More Summary

Claiming Confirmation of the Amyloid Hypothesis in Alzheimer's Disease

last weekHealth / Aging : Fight Aging

Most of the research community proceeds under the assumption that amyloid, deposits of misfolded proteins that form in tissues, is a causative agent in Alzheimer's disease. Amyloid levels rise with age, probably due to progressive failure of clearance mechanisms. Show More Summary

Towards the Indefinite Postponement of Menopause

2 weeks agoHealth / Aging : Fight Aging

The future elimination of menopause through medical advances to treat aging has been in the news of late. Menopause is an undesirable thing that happens during aging, and the ultimate objective of rejuvenation research projects is to indefinitely postpone all of the undesirable things that happen during aging. Show More Summary

Considering Cellular Senescence in the Development of Type 2 Diabetes in Aging

2 weeks agoHealth / Aging : Fight Aging

To be clear, type 2 diabetes is a self-inflicted harm for the majority of sufferers, caused by too much food and too much fat tissue carried over the years. It is a condition that can be turned back even in comparatively late stages by nothing more than weight loss and a much reduced diet. Show More Summary

NAD Mechanisms Necessary for Calorie Restriction Benefits

2 weeks agoHealth / Aging : Fight Aging

Nicotinamide adenine dinucleotide cycles between two forms, NAD+ and NADH, in the course of participating in important cellular processes such as the mitochondrial respiration whose dysfunction is implicated as a cause of aging. Earlier...Show More Summary

A Demonstration of Reduced Life Span via Mitochondrial Mutations, but is it Relevant?

2 weeks agoHealth / Aging : Fight Aging

Mitochondria are bacteria-like organelles within cells responsible for, among other things, generating the adenosine triphosphate (ATP) molecules used as a chemical energy stores to power cellular activities. This process produces aShow More Summary

Transplanted Dopamine Neurons Can Last a Long Time

2 weeks agoHealth / Aging : Fight Aging

Many cell transplants have been shown to produce no long-lasting cells in the recipient. In stem cell treatments, for example, it is frequently the case that the stem cells have a short-term effect on the signaling environment that boosts...Show More Summary

Linking Blood Vessel Degeneration with Age-Related Failure of Amyloid-? Clearance

2 weeks agoHealth / Aging : Fight Aging

Amyloid-? is one of the forms of misfolded protein that accumulate in tissues with age, precipitating to form solid clumps and fibrils. This one forms in the brain and is associated with Alzheimer's disease. Amyloid levels are fairly...Show More Summary

Growth Hormone and Growth Hormone Receptor Required for Life Extension Due to Methionine Restriction

2 weeks agoHealth / Aging : Fight Aging

Methionine is one of the essential amino acids for mammals, a molecule necessary for synthesis of proteins but which our biochemistry cannot manufacture from scratch. Thus we have to obtain methionine from our diets, and without it we will die. Show More Summary

HIF-1 and AMPK in Regulation of Mitochondrial Generation of Reactive Oxygen Species

2 weeks agoHealth / Aging : Fight Aging

Many of the varied genes and proteins that can be manipulated to extend longevity in lower animals are associated with mitochondrial function, and specifically the pace at which mitochondria generate reactive oxygen species (ROS) inShow More Summary

Enhanced Catalase in the Mitochondria Improves Muscle Function in Aging

2 weeks agoHealth / Aging : Fight Aging

Mitochondria are the cell's power plants, swarming in bacteria-like herds to create chemical energy stores. They bear their own DNA, distinct from that in the cell nucleus. This mitochondrial DNA can become damaged in aging and someShow More Summary

A Mechanism for Calorie Restriction to Reduce Both DNA Damage and Cellular Senescence

2 weeks agoHealth / Aging : Fight Aging

The practice of calorie restriction, consuming fewer calories while still obtaining optimal levels of dietary micronutrients, has been demonstrated to greatly improve measures of health in humans and slow the progress of near every measure of degenerative aging in numerous species in the laboratory. Show More Summary

A Look at the Current State of Drug Treatments for Amyloidosis

2 weeks agoHealth / Aging : Fight Aging

Amyloids are formed from handful of types of misfolded proteins that interact to form insoluble deposits in tissues. The presence of amyloid grows with aging, and eventually causes the serious, fatal disruption of tissue function found in the family of amyloidosis conditions. Show More Summary

Female Survival Advantage Diminishes with Age

2 weeks agoHealth / Aging : Fight Aging

Women live longer than men, and while there is no shortage of theories as to why this is the case, the research community has yet to convincingly demonstrate which of them are correct. Adding an additional twist that will need to beShow More Summary

BioWatch News on Rejuvenation Biotechnology 2014

2 weeks agoHealth / Aging : Fight Aging

BioWatch News is a market analysis venture focused on biotechnology, especially medical research and development. This is a fairly common business model: find a niche and help to explain it to investors. People with a lot of money at stake in the market will pay a proportionally greater price for good articles and analysis. Show More Summary

Blocking Blood Vessel Inflammation to Diminish Atherosclerosis

2 weeks agoHealth / Aging : Fight Aging

Researchers have a found a way to selectively interfere with inflammatory processes in blood vessel walls so as to slow the onset of atherosclerosis: Normally, the lining of blood vessels, or endothelium [ignores] the many cells and other factors rushing by in the bloodstream. Show More Summary

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