Blog Profile / Fight Aging

Filed Under:Health / Aging
Posts on Regator:3298
Posts / Week:9
Archived Since:April 26, 2008

Blog Post Archive

Telomerase Therapies and Cancer Risk

11 hours agoHealth / Aging : Fight Aging

To date progress in the development of stem cell treatments has been accompanied by a markedly lower risk of cancer than was expected at the outset. The characteristic decline in stem cell activity with age is believed to be an evolutionary...Show More Summary

Even Perception of Food Scarcity Modifies Metabolism in Short-Lived Species

20 hours agoHealth / Aging : Fight Aging

Calorie restriction has a powerful effect on longevity in short-lived species such as worms, flies, and mice, and produces impressive health benefits in humans. In at least some species it appears that the mechanisms involved include perception of food scarcity, and that this can be manipulated independently of calorie intake and dietary content. Show More Summary

DNA Damage and Interferon in Aging

21 hours agoHealth / Aging : Fight Aging

Researchers here identify one of the mechanisms linking severe forms of DNA damage and cellular senescence. DNA damage accumulates with age, and so too do senescent cells: falling into a senescent state is an evolved response to damage...Show More Summary

Rejuvenation Biotechnology Update for Q2 2015

yesterdayHealth / Aging : Fight Aging

The Methuselah Foundation and SENS Research Foundation collaborate to put out a quarterly newsletter for members of the 300, people who pledge to donate $25,000 over 25 years to research and development aimed at extending healthy life spans. Show More Summary

Towards a Platform for Cost-Effective Personalized Cancer Immunotherapy, Tailored to the Patient and Tumor

yesterdayHealth / Aging : Fight Aging

If you live long enough, you will get cancer. It's just a matter of time and odds, and thus any future rejuvenation toolkit must include robust medical technology capable of curing cancer. The principal challenge of cancer research is...Show More Summary

Aging as Neither Failure nor Achievement of Natural Selection

yesterdayHealth / Aging : Fight Aging

There exist ageless or near-ageless species, such as hydra. There also exist species that do age and die, but show very little sign of functional degeneration until very close to the end, such as naked mole-rats. Why, then, do near all...Show More Summary

Calorie Restriction Makes Old Muscle Metabolism More Youthful

2 days agoHealth / Aging : Fight Aging

The rudiments of rejuvenation treatments that will emerge in the 2020s and 2030s are presently under development at an early stage in the laboratory, largely with very limited funding and attention. It is true that portions of the rejuvenation...Show More Summary

Economic Level and Human Longevity

2 days agoHealth / Aging : Fight Aging

This study from China makes use of the large economic variation between regions of the country and economic growth over much of the past century to investigate correlations between wealth and longevity. Their results favor the present...Show More Summary

An Interview with Aubrey de Grey

2 days agoHealth / Aging : Fight Aging

A recent interview with Aubrey de Grey of the SENS Research Foundation, one of the few groups with a focus on accelerating progress towards the medical control of degenerative aging: C: For those who are not familiar with you, let us know more about your project. Show More Summary

The Dearth of Altruism, the Calculation of Self-Interest

3 days agoHealth / Aging : Fight Aging

The latest edition of Rejuvenation Research is assembled online. I thought I'd direct your attention to this thought for the day paraphrased from Aubrey de Grey's editorial: Let's start with Pasteur. Few would deny that the adoptionShow More Summary

Nebulous Opposition to the Defeat of Aging

3 days agoHealth / Aging : Fight Aging

What is so terrible about the prospect of failing to suffer years of hideous pain, disfigurement, and disability that it forces people to wax lyrical and beat their breasts and say, woe is me, we might have the chance to not suffer and...Show More Summary

On Targeting Secretase in Alzheimer's Disease

3 days agoHealth / Aging : Fight Aging

The slow progress towards viable therapies for Alzheimer's disease based on clearance of ?-amyloid, such as via immunotherapy, has led to a broadening of approaches. Many research groups are looking at other theories on causative mechanisms...Show More Summary

Supercentenarians Awards: $1 Million for the First 123-Year-Old

4 days agoHealth / Aging : Fight Aging

Dmitry Kaminskiy of Deep Knowledge Ventures is one of a small group of technology entrepreneurs turned venture investors with a strong interest in bringing aging under medical control. I think the size of this group will grow in theShow More Summary

A Possible Cause Identified for the Decline in Natural Killer Cells in Old Mice

4 days agoHealth / Aging : Fight Aging

The aging immune system becomes dysfunctional and inefficient for a number of reasons, such as too many cells in its limited repertoire becoming specialized memory cells, leaving too little capacity for the killer T cells responsible for destroying pathogens. Show More Summary

A Possible Path to Prevent Scarring in Mammals

4 days agoHealth / Aging : Fight Aging

Scarring occurs in mammals but not in highly regenerative species such as salamanders. Some research results from past years suggest that scar formation isn't an essential part of the mammalian healing process, such as the ability of MRL mice to heal minor wounds without scars. Show More Summary

A Little mTOR Triumphalism

last weekHealth / Aging : Fight Aging

It's always good to listen to viewpoints that you happen to disagree with. This is why I pay attention to research strategies and researchers informed by programmed aging theories such as the hyperfunction hypothesis that builds on antagonistic pleiotropy. Show More Summary

Autologous Fat Cell Transplant Reduces Osteoarthritis Symptoms

last weekHealth / Aging : Fight Aging

This is a good example of first generation cell therapies that have been available via medical tourism for quite some time, with enough information available for patients to make an informed decision about use, but are only now working...Show More Summary

The Low-Hanging Fruit of Cell Therapy Development

last weekHealth / Aging : Fight Aging

It is always going to be easier to develop treatments for non-vital organs, and in some cases work on cell therapies for those organs can be simpler and less costly for other, unrelated reasons. Thus progress is faster in these areas,...Show More Summary

A Brief Introduction to Model Organisms in Aging Research

last weekHealth / Aging : Fight Aging

The varied approaches to research developed over past decades by the aging research community are driven by two things: firstly that we live for a long time, and secondly the absence of a way to accurately determine an individual's biological age. Show More Summary

The Old are Slowly Becoming Younger

last weekHealth / Aging : Fight Aging

Aging is accumulated cell and tissue damage, and the slow growth of healthy human life expectancy that has taken place over the past two centuries thus reflects a lesser load of a damage present in individuals of a given age. The old...Show More Summary

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