Blog Profile / Fight Aging

Filed Under:Health / Aging
Posts on Regator:4923
Posts / Week:10.5
Archived Since:April 26, 2008

Blog Post Archive

The California Life Company is Secretive, but Sadly Also Probably Irrelevant

4 hours agoHealth / Aging : Fight Aging

It will not be news to this audience that the California Life Company, or Calico for short, Google's venture into aging research, is secretive. Outside of the staff, few people can do more than read the tea leaves regarding what exactly they are up to. Show More Summary

Using CRISPR to Suppress Cytokine Receptors and Reduce Inflammation

16 hours agoHealth / Aging : Fight Aging

Researchers believe they have established a method of reducing inflammation via epigenetic alterations that can in principle be broadly applied to a range of conditions in which inflammation is important. Inflammation is significantShow More Summary

Relations Between the Endoplasmic Reticulum and Mitochondria in Aging

16 hours agoHealth / Aging : Fight Aging

This open access paper serves as a reminder that there is an enormous amount of complexity yet to be mapped and understood in cellular biochemistry, let alone in the way that this biochemistry changes over the course of aging. For example,...Show More Summary

Further Investigations of Cellular Senescence in Muscle Aging and Frailty

yesterdayHealth / Aging : Fight Aging

As a topic for aging research, cellular senescence passed its tipping point a few years ago. Prior to that growth of interest and attention it was a struggle to raise funding for this area of work, and thus it didn't matter how compelling the evidence was for its involvement in the processes of aging. Show More Summary

A Nanoparticle Cancer Vaccine Effective Against Multiple Varieties of Cancer

yesterdayHealth / Aging : Fight Aging

The most important projects in cancer research are those that might produce therapies effective against many different types of cancer. There are too many varieties of cancer and individual tumors can evolve too rapidly for the research community to achieve its goals by working on highly specific therapies. Show More Summary

A Mechanism to Link Air Pollution and Cardiovascular Disease

yesterdayHealth / Aging : Fight Aging

Air pollution is associated with increased mortality and risk of a variety of age-related diseases, but as is often the case in human epidemiological data it isn't all that clear as how much of this is due to direct versus indirect effects. Show More Summary

More Evidence for Senescent Cells as a Significant Cause of Osteoarthritis

2 days agoHealth / Aging : Fight Aging

UNITY Biotechnology has obtained a large amount of venture funding in order to work on senolytic therapies, treatments capable of removing significant numbers of the senescent cells that accumulate with advancing age. Cellular senescence...Show More Summary

An Approach to Deliver Chimeric Antigen Receptor T Cells to Solid Tumors

2 days agoHealth / Aging : Fight Aging

The approaches to cancer therapies that we should pay attention to are those capable of targeting many different types of cancer. The only practical way to meaningfully accelerate progress towards robust control of cancer as a wholeShow More Summary

Exercise Improves Cognitive Function in Older Individuals

2 days agoHealth / Aging : Fight Aging

Researchers here analyze the results from dozens of papers in which exercise was shown to have a beneficial effect on cognitive function in older adults. The broad consensus is that the mechanisms for this effect primarily involve vascular health. Show More Summary

SENS Research Foundation Expands Collaboration with the Buck Institute to Work on Senescent Cells and Immune Aging

3 days agoHealth / Aging : Fight Aging

The SENS Research Foundation and the Buck Institute for Research on Aging are both based in the Bay Area, California, and collaborate on a small variety of projects relevant to the development of rejuvenation therapies. This includes...Show More Summary

Osteoarthritis as an Inflammatory Condition

3 days agoHealth / Aging : Fight Aging

This open access paper discusses current views on the degree to which osteoarthritis is driven by inflammation, as is the case for many other age-related diseases. With aging the immune system declines into a malfunctioning state ofShow More Summary

Evidence for Fat-Triggered Immune Dysfunction in the Liver to Contribute to the Symptoms of Type 2 Diabetes

3 days agoHealth / Aging : Fight Aging

In this research, scientists explore a link between the presence of excess fat and the dysfunctional blood sugar regulation that is characteristic of type 2 diabetes. The vast majority of type 2 diabetes patients suffer the condition...Show More Summary

Fight Aging! Newsletter, April 24th 2017

4 days agoHealth / Aging : Fight Aging

Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and...Show More Summary

If Much Older than 30, Save More Aggressively Over the Next Decade or Two

6 days agoHealth / Aging : Fight Aging

Five years from now, it will be possible to fly to an overseas clinic and undergo a treatment that will clear out between a quarter and half of the senescent cells in your body. That will to some degree damp down fibrosis, restore tissue...Show More Summary

How Does Tau Cause Neurodegeneration?

6 days agoHealth / Aging : Fight Aging

As research progresses, it is becoming clear that the situation for amyloid-? and tau in the aging brain is quite similar at the high level. As amounts increase with advancing age, perhaps due to the progressive failure of clearanceShow More Summary

Increased Cardiac Troponin T Associated with Neuromuscular Junction Aging

6 days agoHealth / Aging : Fight Aging

Decline in the neuromuscular junctions that connect nerve tissue to muscle tissue is one of the ways in which muscles age and lose strength. Researchers here examine changing levels of proteins in neuromuscular junctions, and identify increased amounts of cardiac troponin T as one of the proximate causes of decline. Show More Summary

Calorie Restriction Slows Progression of the Earliest Stages of Cancer

last weekHealth / Aging : Fight Aging

The practice of calorie restriction has been shown to extend both healthy and overall life span in near every species tested to date - though of course the human life span data is still too sparse to do more than make educated guesses. Show More Summary

Show Your Appreciation for the Fundraising Work of

last weekHealth / Aging : Fight Aging

The and Life Extension Advocacy Foundation (LEAF) volunteers have over the past few years put together and maintained a crowdfunding infrastructure used to successfully raise hundreds of thousands of dollars for rejuvenation research projects. Show More Summary

A Perspective on Clinical Translation of Senolytic Drugs

last weekHealth / Aging : Fight Aging

Researchers here discuss the path to the clinic for the first batch of senolytic drugs, compounds that nudge senescent cells into self-destruction. Senescent cells accumulate with age, and secrete signals that disrupt tissue function and produce chronic inflammation. Show More Summary

Transfusion of Young Blood Associates TIMP2 with Aging and Cognitive Function

last weekHealth / Aging : Fight Aging

A growing collection of studies and projects have emerged from parabiosis experiments in which the circulatory systems of a young and an old individual are joined. The old individual experiences a modest reduction in the impact of aging, in measures such as regeneration, stem cell activity, and more. Show More Summary

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