Blog Profile / Fight Aging

Filed Under:Health / Aging
Posts on Regator:4369
Posts / Week:10
Archived Since:April 26, 2008

Blog Post Archive

Increased Levels of Neuregulin-1 Reduce Amyloid Plaques and Improve Memory in a Mouse Model of Alzheimer's Disease

yesterdayHealth / Aging : Fight Aging

Researchers have recently demonstrated that raised levels of neuroregulin-1 in parts of the brain can reduce the build up of amyloid plaque and improve measures of memory in a mouse lineage engineered to reproduce the features of Alzheimer's disease. Show More Summary

A Bleak Outlook on Aging

yesterdayHealth / Aging : Fight Aging

As illustrated by this study, most people don't think about their own future aging, and when they do they are unaware that we stand on the verge of new medical technologies that will greatly extend healthy life spans. We humans have evolved a masterful ability to avoid thinking about the future when it looks likely to be unpleasant. Show More Summary

A Potential Way to Speed the Recovery Phase of an Immune System Reboot

yesterdayHealth / Aging : Fight Aging

There is great potential in the destruction and recreation of the immune system: the removal of all immune cells and replacement with new cells. This is an approach capable of curing autoimmune conditions, but perhaps more importantly it might also be used to clear out much of the dysfunction of the aged immune system. Show More Summary

A Small Selection of Recent Research on Lifestyle Choices and Aging

2 days agoHealth / Aging : Fight Aging

Today I'll point out a recent selection of studies on lifestyle choices and life expectancy: the costs of bad choices and the benefits of good choices. The numbers are not particular new, but it is good to be occasionally reminded of the bounds of the possible when it comes to choice versus technology. Show More Summary

A Scanning Approach to Detect Transthyretin Amyloid Buildup in the Heart

2 days agoHealth / Aging : Fight Aging

Accumulation of transthyretin amyloid is one of the root causes of aging. This is a form of protein misfolding that products harmful deposits, amyloids, in tissues. In recent years this type of amyloid has been identified as the major...Show More Summary

Marmosets in Aging Research

2 days agoHealth / Aging : Fight Aging

The use of animals in the study of aging has always meant striking a balance between species life span and distance from humans in the evolutionary tree of life. Very short-lived species such as worms and flies allow for much cheaper,...Show More Summary

Criticizing Programmed Theories of Aging

3 days agoHealth / Aging : Fight Aging

Today I'll point out an open access critique of programmed aging theories by the originator of the disposable soma theory of aging, one of the modern views of aging as accumulated damage rather than programming. The question of how and why we age is wrapped in a lot of competing theory, but of great practical importance. Show More Summary

Ghrelin Receptor and Inflammaging

3 days agoHealth / Aging : Fight Aging

Ghrelin is related to the hunger response, but has a very broad range of influences on many tissues and systems, including immune system activities. Inflammaging is the name given to the inflammation-focused view of the characteristic decline and dysfunction of the immune system with aging. Show More Summary

Shorter Period of Rapamycin Treatment in Mice Produces Greater Slowing of Aging

3 days agoHealth / Aging : Fight Aging

Rapamycin, an immunosuppressant and MTOR inhibitor, is known to slow aging in mice - though it has been debated whether this extension of life span is actually a slowing of aging versus a lower rate of cancer. Researchers here try aShow More Summary

An Interview with Kelsey Moody of Ichor Therapeutics, Bringing a SENS Therapy for Macular Degeneration to the Clinic

4 days agoHealth / Aging : Fight Aging

As I mentioned last week, earlier this year Fight Aging! invested a modest amount in the Ichor Therapeutics initiative to develop a treatment for macular degeneration, joining a number of other amateur and professional investors in helping to get this venture started. Show More Summary

Cells can Transfer Lysosomes, Spreading Damaging Age-Related Waste Materials

4 days agoHealth / Aging : Fight Aging

It is known that cells can transfer mitochondria from one to another under some circumstances, and here researchers demonstrate that they can transfer lysosomes as well. The lysosomes in a cell play the role of recycling units, breaking down damaged structures and waste proteins. Show More Summary

Enhancing Cell Therapy to Enable Greater Recovery Following Stroke

4 days agoHealth / Aging : Fight Aging

Researchers here demonstrate a method of improving the effectiveness of a stem cell therapy targeted to brain tissues, enabling the treatment to repair more of the damage caused by a stroke: A team of researchers has developed a therapeutic technique that dramatically increases the production of nerve cells in mice with stroke-induced brain damage. Show More Summary

Mapping the Role of Foxn1 in Thymic Function

5 days agoHealth / Aging : Fight Aging

Researchers have of late been mapping the activities and relationships of Forkhead box protein N1 (Foxn1) in the thymus, and the paper I'll point out today outlines some of the most recent findings. Sadly it isn't open access, but I'm sure that won't stop the determined reader in this day and age. Show More Summary

Development of a Cell Therapy to Increase Remyelination in the Brain

5 days agoHealth / Aging : Fight Aging

In this open access paper, results are presented for an animal study of an approach to increasing the pace of remyelination in the brain. Myelin acts as sheathing for the axons that connect nerve cells; when it is degraded, insufficiently maintained, or damaged, the result is dysfunction in the nervous system. Show More Summary

Towards a Regenerative Therapy for the Lacrimal Gland and Dry Eyes

5 days agoHealth / Aging : Fight Aging

The lacrimal gland provides moisture for the eyes, and like all parts of our physiology is prone to decline and failure in old age. Dry eye conditions, some of which are painful and debilitating, are common in old people. Researchers...Show More Summary

Fight Aging! Newsletter, August 22nd 2016

6 days agoHealth / Aging : Fight Aging

Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and...Show More Summary

The Geroscience Network: Determined to Slow Aging through Medical Science

last weekHealth / Aging : Fight Aging

Across the last twenty years or so two very important, slow-moving battles over ideas and strategy have been fought within and around the aging research community. The first was to gain acknowledgement that the treatment of aging as a medical condition is a viable goal, and thus obtain the necessary support to make progress towards that goal. Show More Summary

Investigating the Role of Hsp70 in Clearing out Damaged Proteins

last weekHealth / Aging : Fight Aging

Heat shock proteins such as the Hsp70 family are involved in the housekeeping processes that keep cells functioning well by destroying damaged proteins. They become active in response to stresses that cause a higher rate of damage to the protein machinery within cells, such as toxicity or heat - and hence the name. Show More Summary

Twins Exhibit Slightly Lower Mortality Rates than Non-Twins

last weekHealth / Aging : Fight Aging

Researchers here report on an interesting finding emerging from epidemiological data on twins, in that twins exhibit modestly lower mortality rates than the rest of the population. The paper focuses on the support and relationship angle,...Show More Summary

Aubrey de Grey at the Launching Longevity Panel, and Announcing Acceptance of the First Paper to be Published on MitoSENS Research

last weekHealth / Aging : Fight Aging

Today I'll direct your attention to a couple of videos, thematically linked by the presence of Aubrey de Grey, cofounder of the SENS Research Foundation and tireless advocate for progress towards working rejuvenation therapies. For the...Show More Summary

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