Blog Profile / EurekAlert: Diseases

Filed Under:Health / Diseases & Conditions
Posts on Regator:751
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Archived Since:September 5, 2016

Blog Post Archive

Mice immunized with synthetic horsepox protected against vaccinia virus

(PLOS) Immunization with a synthetic horsepox virus offers mice similar protection to immunization with vaccinia virus against a lethal dose of vaccinia, according to a study published Jan. 19, 2018, in the open-access journal PLOS ONE by Ryan Noyce from the University of Alberta, Canada, and colleagues.

Creation of synthetic horsepox virus could lead to more effective smallpox vaccine

(University of Alberta Faculty of Medicine & Dentistry) UAlberta researchers created a new synthetic virus that could lead to the development of a more effective vaccine against smallpox. The discovery demonstrates how techniques based on the use of synthetic DNA can be used to advance public health measures.

The flu vaccine could get a much-needed boost

(University of California - Los Angeles Health Sciences) More than 700,000 Americans were hospitalized due to illnesses associated with the seasonal flu during the 2014-15 flu season, according to federal estimates. A radical new approach to vaccine development at UCLA may help lower that figure for future flu seasons.

Launch of 'DeWorm3' collection

(PLOS) PLOS Neglected Tropical Diseases is happy to announce the publication of a new collection, 'DeWorm3' on Jan. 18, 2018.

Genetic sequencing points to endemic origin of monkeypox virus outbreak in Nigeria

(US Army Medical Research Institute of Infectious Diseases) Scientists working to control a human outbreak of monkeypox virus (MXPV) in Nigeria performed genetic sequencing of patient samples, revealing that the outbreak likely originated from a source within the country. Show More Summary

Schistosoma vaccine to enter phase Ib clinical trial

(George Washington University) Researchers at Baylor College of Medicine, in collaboration with a team of researchers at the George Washington University and the Rene Rachou Institute, have received funding from the National Institutes of Health for a Phase Ib clinical trial for a Schistosomiasis vaccine in an endemic area of Brazil.

Zika virus damages placenta, which may explain malformed babies

(Oregon Health & Science University) New researcher shows how Zika virus infection in five pregnant rhesus monkeys caused placental tissues to become thickened and inflamed, resulting in less oxygen being transported across the placenta and to the baby.

Mass. General study reveals how MRSA infection compromises lymphatic function

(Massachusetts General Hospital) Massachusetts General Hospital investigators find that MRSA infection impairs the ability of lymphatic vessels to pump lymphatic fluid to lymph nodes in mouse models, which may contribute to the frequent recurrences of MRSA infection experienced by patients.

New warning system discovered in the immune defence

(Linköping University) Researchers at Linköping University in Sweden have discovered a previously unknown warning system that contributes to the body's immune system. Mitochondria in the white blood cells secrete a web of DNA fibers that raises the alarm. Show More Summary

NIH study supports use of short-term HIV treatment interruption in clinical trials

(NIH/National Institute of Allergy and Infectious Diseases) A short-term pause in HIV treatment during a carefully monitored clinical trial does not lead to lasting expansion of the HIV reservoir nor cause irreversible damage to the immune system, new findings suggest.

Different strains of same bacteria trigger widely varying immune responses

(PLOS) Genetic differences between different strains of the same pathogenic bacterial species appear to result in widely varying immune system responses, according to new research published in PLOS Pathogens.

Human protein may aid neuron invasion by virus that causes hand, foot, and mouth disease

(PLOS) A human protein known as prohibitin may play a significant role in infection of the nervous system by EV71, one of several viruses that can cause hand, foot, and mouth disease. Issac Too of the National University of Singapore and colleagues highlight this finding in a new PLOS Pathogens study.

By altering bone marrow, training can prepare innate immune system for future challenges

(University of Pennsylvania) In a new paper, published in Cell, researchers at the University of Pennsylvania collaborated with an international team to show how the innate immune system, which responds more generally to dangers detected in the body, can be trained to 'remember' past threats and respond more robustly to future challenges.

Long-lasting adaptations of the innate immune system through the bone marrow

(Radboud University Nijmegen) The immune system not only detects and destroys pathogens such as microbes but also plays a role in the onset of diseases such as arteriosclerosis. Scientists from Radboud university medical center, Bonn, Dresden and Pennsylvania, studied a new mechanism that regulates the immune system's functioning. Show More Summary

Biofilm buster treats drug-resistant infections

(American Association for the Advancement of Science) Scientists have created a potent antibacterial agent that killed drug-resistant microbes and even eradicated stubborn pathogens growing in biofilms, which can be 10 to 1,000 times more tolerant to antibiotics than free-living bacteria.

Immune response to Zika virus contributes to fetal harm

(Yale University) The same proteins that mount a potent immune response to Zika viral infection can also harm the placenta and fetal development, according to a Yale-led study published in Science Immunology.

How Zika infection drives fetal demise

(Howard Hughes Medical Institute) An interferon cell receptor spurs cell suicide in fetuses infected with the Zika virus and could play a role in certain pregnancy complications.

Hijacker parasite blocked from infiltrating blood

(Walter and Eliza Hall Institute) A major international collaboration led by Melbourne researchers has discovered that the world's most widespread malaria parasite infects humans by hijacking a protein the body cannot live without. The researchers were then able to successfully develop antibodies that disabled the parasite from carrying out this activity.

Tick exosomes may aid transmission of viruses to vertebrates

(PLOS) Scientists have shown for the first time that exosomes from tick cells can aid transmission of viral proteins and genetic material from arthropod to vertebrate host cells, according to new research published in PLOS Pathogens...

Penn Vet's Boris Striepen receives $1.8m grant to fight deadly diarrheal disease in infants

(University of Pennsylvania) Boris Striepen, PhD, Professor of Pathobiology at the School of Veterinary Medicine at the University of Pennsylvania, has received a $1.8-million, three-year grant from the Bill & Melinda Gates Foundation to enable the development of drugs for cryptosporidiosis, a diarrheal disease caused by microscopic parasites.

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