Blog Profile / ScienceDaily: Alzheimer

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Filed Under:Mental Health / Alzheimer's
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Archived Since:September 12, 2016

Blog Post Archive

Older adults' difficulties with focusing can be used to help put a face to a name

Everyone has experienced the awkward situation of meeting someone and then forgetting their name shortly after. Among older adults, this happens more often than not. Researchers have discovered a new method to resolve this problem by tapping into a natural memory change during aging.

Cell therapy could improve brain function for Alzheimer's disease

Inhibitory interneurons are particularly important for managing brain rhythms. Researchers have uncovered the therapeutic benefits of genetically improving these interneurons and transplanting them into the brain of a mouse model of Alzheimer's disease.

Brain mechanism involved in language learning

Psychologists found that when we learn the names of unfamiliar objects, brain regions involved in learning actively predict the objects the names correspond to.

Physically fit women nearly 90 percent less likely to develop dementia

Women with high physical fitness at middle age were nearly 90 percent less likely to develop dementia decades later, compared to women who were moderately fit, according to a new study. The study measured the women's cardiovascular fitness based on an exercise test.

Making new memories is a balancing act

Salk scientists discover that brain storage capacity is dynamic and varies by region.

Scientists search for the clocks behind aging brain disorders

To understand the link between aging and neurodegenerative disorders such as Alzheimer's disease, scientists compared the genetic clocks that tick during the lives of normal and mutant flies. They found that altering the activity ofShow More Summary

Thyroid gene variation may increase risk for Alzheimer's disease in African Americans

African Americans with a common genetic variation are at increased risk for developing Alzheimer's disease, while European Americans with the same variation are not, according to a new study.

Long-term proton pump inhibitor use does not increase hip fracture risk among Alzheimer's patients

Long-term proton pump inhibitor (PPI) use does not increase the risk of hip fracture among persons with Alzheimer's disease, according to a new study.

Scientists discover a key function of ALS-linked protein

The protein FUS, whose mutation or disruption causes many cases of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), works as a central component of one of the most important regulatory systems in cells, according to a new study.

Culprit in Parkinson's brain cell die-off

Researchers investigate the connection between misfolded proteins and the destruction of mitochondria in neurons.

Changing size of neurons could shed light on new treatments for motor neuron disease

New research improves our understanding of how motor nerve cells (neurons) respond to motor neuron disease, which could help us identify new treatment options.

Novel biomarkers for future dementia risk

Medical researchers have identified novel biomarkers of risk for future dementia.

Enhancement of neurotrophic factor signaling may improve memory functions

Treatments targeted to enhance brain neurotrophic factor signaling could improve memory functions in Alzheimer's disease even though they don't alter brain amyloid burden, according to recent research.

'Epigenetic landscape' is protective in normal aging, impaired in Alzheimer's disease

Researchers profiled the epigenomic landscape of Alzheimer's brains, specifically in one of the regions affected early in AD, the lateral temporal lobe. They compared these to both younger and elderly cognitively normal control subjects. Show More Summary

Polygenic risk score may identify Alzheimer's risk in younger populations

For the first time, scientists have determined that an Alzheimer's disease (AD) polygenic risk score can be used to correctly identify adults with mild cognitive impairment (MCI) who were only in their 50s.

'Filter' hones GWAS results to help researchers avoid dead ends

A genetics research team has solved a dilemma facing researchers who use genomewide association studies (GWAS) by developing a new approach that strategically 'filters' which genes are worth further study. The researchers hope this strategy...Show More Summary

Stem-cell study points to new approach to Alzheimer's disease

Improving the trafficking of brain-cell proteins to reduce toxic buildup holds possibilities for new therapies against Alzheimer's disease.

A neuron can cause a domino effect

If the sense of smell disappears, this can indicate a disease such as Alzheimer's or Parkinson's disease. However, unlike previously assumed, general degenerations in the nervous system do not play a leading role in the loss of the sense of smell with increasing age, but individual nerve cells or classes of nerves are decisive.

ALS-linked protein's journey into nervous system cells more complex than we thought

Scientists have developed a better understanding of a key protein associated with brain diseases including ALS (motor neuron disease) and dementia by studying how it enters central nervous system cells.

Unpacking asymmetric cell division

Scientists have found a new role for proteins that play important roles in asymmetric division, which may play a role in tumor formation or neurodevelopmental disorders.

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