Blog Profile / ScienceDaily: Healthy Aging

Filed Under:Health / Aging
Posts on Regator:333
Posts / Week:5.1
Archived Since:September 12, 2016

Blog Post Archive

Epigenetic aging linked to bipolar disorder

Bipolar disorder may involve accelerated epigenetic aging, which could explain why persons with the disorder are more likely to have -- and die from -- age-related diseases, according to researchers.

People say they want to live longer -- if in good health

Individually most people only want to live long lives if they will be healthy, according to a new study.

Inhibiting TOR boosts regenerative potential of adult tissues

Adult stem cells replenish dying cells and regenerate damaged tissues throughout our lifetime. We lose many of those stem cells, along with their regenerative capacity, as we age. Working in flies and mice, researchers discovered that TOR, a nutrient sensing pathway which is central to the aging process, drives the loss of adult stem cells. Show More Summary

Mutations in neurons accumulate as we age; may explain normal cognitive decline and neurodegeneration

Researchers used whole-genome sequencing of individual neurons and found strong evidence that brain mutations accumulate as we age. They also found that mutations accumulate at a higher rate in people with genetic premature aging disorders causing early brain degeneration.

Canola oil linked to worsened memory and learning ability in Alzheimer's

Canola oil is one of the most widely consumed vegetable oils, yet little is known about its health effects. Now, a study links canola oil consumption in the diet with worsened memory, worsened learning ability and weight gain in mice which model Alzheimer's disease. It's the first study to suggest that canola oil is more harmful than healthful for the brain.

Number of genetic markers linked to lifespan triples

Researchers have studied 389,166 volunteers who gave DNA samples to the UK Biobank, US Health and Retirement Study and the Wisconsin Longitudinal Study. In addition to confirming the eight genetic variants that had already been linked to longevity, this study found 17 more to expand the list of known variants affecting lifespan to 25 genes, with some sex-specific.

Genes behind higher education linked to lower risk of Alzheimer’s

Using genetic information, researchers provide new evidence that higher educational attainment is strongly associated with a lower risk of Alzheimer’s disease.

Alzheimer's damage in mice reduced with compound that targets APOE gene

People who carry the APOE4 genetic variant face a substantial risk for developing Alzheimer's disease. Now, researchers have identified a compound that targets the APOE protein in the brains of mice and protects against damage induced by the Alzheimer's protein amyloid beta. The findings indicate that APOE could potentially be a real target for treatment or prevention.

Healthy mitochondria could stop Alzheimer's

Using a bioinformatics and experimental approach, scientists have found that rendering mitochondria resistant to damage can halt diseases caused by amyloid toxicity, such as Alzheimer's disease.

When the nose doesn't know: Can loss of smell be repaired?

Researchers are examining the behavior of stem cells within the context of aging and loss of smell. They report mechanisms to regenerate adult stem cells in mice to restore smell cells: it mimics induced pluripotency, but is simpler, involving only two Yamanaka factors.

Obesity increases dementia risk

People who have a high body mass index (BMI) are more likely to develop dementia than those with a normal weight, according to a new study.

Gene variant that protects against Alzheimer's disease identified

Research details a novel and promising approach in the effort to treat Alzheimer's disease. Medical researchers have discovered a rare genetic variant that provides a protective effect for high-risk individuals -- elderly people who carry known genetic risk factors for Alzheimer's-- who never acquired the disease.

More than half of US children will have obesity as adults if current trends continue

If current trends in child obesity continue, more than 57 percent of today's children in the US will have obesity at age 35, according to a new study.

No evidence that gadolinium causes neurologic harm

There is no evidence that accumulation in the brain of the element gadolinium speeds cognitive decline, according to a new study.

Link between immune function, osteoarthritic pain and progression

Monocytes, the white blood cells necessary to regulate immune responses, were more activated and pro-inflammatory in women with osteoarthritis, and that elevated inflammation and body mass index were associated with this increased activation, report investigators.

Severity of post-operative delirium relates to severity of cognitive decline

There is increasing evidence that the level of delirium in post-surgical patients is associated with the level of later cognitive decline in those same patients.

Health of people with cystic fibrosis shows positive trends in US and Canada

Research comparing cystic fibrosis patients in the United States and Canada showed that, although patients' nutritional status and lung function improved in both countries from 1990 to 2013, the US improvement rate was faster. Nutritional status and lung function are related to survival in cystic fibrosis. Show More Summary

Good cells gone bad: Scientists discover PINK-SNO[W]

A new study is the first to show precisely how a process in nerve cells, called the S-nitrosylation (SNO) reaction, may contribute to Parkinson's disease.

New mechanisms found of cell death in neurodegenerative disorders

New mechanisms of cell death have now been discovered, which may be involved in debilitating neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease, report scientists.

New details on aged brain, Alzheimer's and dementia

In a comprehensive analysis of samples from 107 aged human brains, researchers have discovered details that will help researchers better understand the biological bases for Alzheimer's disease and dementia in older populations.

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