|Filed Under:||Health / Aging|
|Posts on Regator:||333|
|Posts / Week:||5.1|
|Archived Since:||September 12, 2016|
Bipolar disorder may involve accelerated epigenetic aging, which could explain why persons with the disorder are more likely to have -- and die from -- age-related diseases, according to researchers.
Individually most people only want to live long lives if they will be healthy, according to a new study.
Adult stem cells replenish dying cells and regenerate damaged tissues throughout our lifetime. We lose many of those stem cells, along with their regenerative capacity, as we age. Working in flies and mice, researchers discovered that TOR, a nutrient sensing pathway which is central to the aging process, drives the loss of adult stem cells. Show More Summary
Researchers used whole-genome sequencing of individual neurons and found strong evidence that brain mutations accumulate as we age. They also found that mutations accumulate at a higher rate in people with genetic premature aging disorders causing early brain degeneration.
Canola oil is one of the most widely consumed vegetable oils, yet little is known about its health effects. Now, a study links canola oil consumption in the diet with worsened memory, worsened learning ability and weight gain in mice which model Alzheimer's disease. It's the first study to suggest that canola oil is more harmful than healthful for the brain.
Researchers have studied 389,166 volunteers who gave DNA samples to the UK Biobank, US Health and Retirement Study and the Wisconsin Longitudinal Study. In addition to confirming the eight genetic variants that had already been linked to longevity, this study found 17 more to expand the list of known variants affecting lifespan to 25 genes, with some sex-specific.
Using genetic information, researchers provide new evidence that higher educational attainment is strongly associated with a lower risk of Alzheimer’s disease.
People who carry the APOE4 genetic variant face a substantial risk for developing Alzheimer's disease. Now, researchers have identified a compound that targets the APOE protein in the brains of mice and protects against damage induced by the Alzheimer's protein amyloid beta. The findings indicate that APOE could potentially be a real target for treatment or prevention.
Using a bioinformatics and experimental approach, scientists have found that rendering mitochondria resistant to damage can halt diseases caused by amyloid toxicity, such as Alzheimer's disease.
Researchers are examining the behavior of stem cells within the context of aging and loss of smell. They report mechanisms to regenerate adult stem cells in mice to restore smell cells: it mimics induced pluripotency, but is simpler, involving only two Yamanaka factors.
People who have a high body mass index (BMI) are more likely to develop dementia than those with a normal weight, according to a new study.
Research details a novel and promising approach in the effort to treat Alzheimer's disease. Medical researchers have discovered a rare genetic variant that provides a protective effect for high-risk individuals -- elderly people who carry known genetic risk factors for Alzheimer's-- who never acquired the disease.
If current trends in child obesity continue, more than 57 percent of today's children in the US will have obesity at age 35, according to a new study.
There is no evidence that accumulation in the brain of the element gadolinium speeds cognitive decline, according to a new study.
Monocytes, the white blood cells necessary to regulate immune responses, were more activated and pro-inflammatory in women with osteoarthritis, and that elevated inflammation and body mass index were associated with this increased activation, report investigators.
There is increasing evidence that the level of delirium in post-surgical patients is associated with the level of later cognitive decline in those same patients.
Research comparing cystic fibrosis patients in the United States and Canada showed that, although patients' nutritional status and lung function improved in both countries from 1990 to 2013, the US improvement rate was faster. Nutritional status and lung function are related to survival in cystic fibrosis. Show More Summary
A new study is the first to show precisely how a process in nerve cells, called the S-nitrosylation (SNO) reaction, may contribute to Parkinson's disease.
New mechanisms of cell death have now been discovered, which may be involved in debilitating neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease, report scientists.
In a comprehensive analysis of samples from 107 aged human brains, researchers have discovered details that will help researchers better understand the biological bases for Alzheimer's disease and dementia in older populations.