Today I'll point out a couple of recent research publications on the topic of the molecular mechanisms of exercise: how it might work to improve health, how it extends healthy life span but not maximum life span in animal studies, and how the response to exercise might be safely improved or otherwise manipulated. Show More Summary
We typically think of habits as bothersome behaviors that affect us as individuals. However, there are habits that couples develop which can be just as bothersome, if not more so. By keeping us from getting the most we can out of our closest bonds with others, they can stand in between us and true relationship happiness.
For some years a faction of researchers have argued that Alzheimer's disease really should be considered a type 3 diabetes, based on the shared risk factors and what is known of the way that it ties into the mechanisms associated with insulin resistance. Show More Summary
An important factor in the speed of development, cost, and availability of future stem cell therapies is the existence of an efficient, reliable way to create large numbers of the specific cell types needed. This is one of the main limiting factors for many areas of medical development in cell-based regenerative medicine. Show More Summary
On Saturday I asked if readers would be interested In a single “interesting stuff” item on Tuesdays and Thursdays since I no longer write full blog posts on those days and I often have more interesting stuff than there is...
Last week we launched the Fight Aging! fundraiser for SENS rejuvenation research programs, work on the biotechnologies needed to repair the cellular and molecular damage that causes aging and all age-related disease. Do we want to see meaningful progress towards the defeat of degenerative aging in our lifetime? Yes, yes we do. Show More Summary
It’s never pleasant to be the target of an insult. However, before you let an insulting remark get the better of you, stop and consider who’s doing the insulting. It’s likely that it’s just a narcissist, trying to feel better by making you feel bad.
Researchers are now able to compare the mutational damage to nuclear DNA in individual long-lived cells such as neurons, which is a step towards measuring how much of this damage there is and how it varies over time and from cell to cell. Show More Summary
This article paints a picture of David Sinclair as one of the important researchers in the move towards treating aging as a medical condition. I'd say that he's certainly good at publicity and fundraising, and has more than done hisShow More Summary
Below is a repost from December 2012, right after the Sandy Hook shootings, and at first I hesitated to publish it again. Then I changed my mind. With yet another god-awful massacre, I think that we in our little community...
This Sunday Elder Music column was launched in December of 2008. By May of the following year, one commenter, Peter Tibbles, had added so much knowledge and value to my poor attempts at musical presentations that I asked him to...
In the traditional world of dating, men ask and women wait to be asked. A new dating app is changing the rules, but what makes women wait in the first place?
EDITORIAL NOTE: I try to keep this weekly links post to nine items or fewer because I believe that too much choice is no choice at all. Even so, I've gone overboard today but there was just so much interesting...
Given the BioViva press release I pointed out earlier today, you may be interested in listening to a Longevity Day roundtable held yesterday, since Elizabeth Parrish of BioViva was participating, as well as Keith Comito of the Life Extension Advocacy Foundation, and a few other names you might recognize. Show More Summary
Have you noticed that it's bill increase season? It is for me – the time of year when notices of an uptick in price arrive from the companies that provide products and services one cannot cancel or do without. My...
Gene therapy to raise levels of the natural antioxidant catalase in mitochondria is one of many methods shown to modestly extend life in mice. Cancer is so very prevalent in mice that it is frequently worth asking whether or not life...Show More Summary
BioViva is one of the small groups interested in bringing telomerase therapies to humans sooner rather than later. It seems they have started in on their small long-term trial of human gene therapy for telomerase activation, and have treated the first volunteer. Show More Summary
Today I'm pleased to announce the launch of this year's Fight Aging! matching fundraiser in support of the work of the SENS Research Foundation, funding scientific programs to speed progress towards working rejuvenation therapies and an end to frailty and disease in aging. Show More Summary
There is something about the prospect of treating the causes of aging and greatly extending healthy life spans that makes otherwise sensible people throw common sense out of the window. If I had a dime for every time I saw incoherent...Show More Summary
Researchers here propose that the domestic dog population is overlooked as a cost-effective source of data on aging. It is certainly the case that there is a broad variation in life span as well as size between canine breeds, and comparative...Show More Summary