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Boosted Microglial Function as an Alzheimer's Therapy

4 hours agoHealth / Aging : Fight Aging

The immune system is a very efficient mechanism for certain types of task, if it can just be harnessed and put to work. Left to its own devices throughout most of a life span it can effectively destroy misbehaving cells, remove some types of harmful protein aggregates, and of course defend against self-replicating invaders of many different types. Show More Summary

Aging in Place – Your Town

14 hours agoHealth / Aging : Time Goes By

I grew up in suburban Oregon and California so I had a good deal of experience with suburban living before I moved here to Lake Oswego, Oregon, four years ago. I also lived for 40 years in New York City...

Effects of Lifestyle or Effects of Aging?

17 hours agoHealth / Aging : Fight Aging

There is a distinction to be drawn between primary and secondary aging, which at this time we might consider as the division between the things you can't yet do anything about on the one hand versus the things can you do something about on the other. Show More Summary

Attempts to Reduce Systematic Inflammation in Aging

17 hours agoHealth / Aging : Fight Aging

Chronic inflammation increases with aging due to a progressive dysfunction of the immune system: it is overactive but yet ineffective, like a failing engine running hot. Inflammation is a necessary part of the immune response, but if...Show More Summary

Are You as Socially Introverted as You Seem?

If you don't want to look socially introverted, you may want to remove those earphones you're wearing. Although you may enjoy the entertainment our mobile devices provide as they provide a soundtrack to our day, you may also be sending unintentional cues telling other people to stay away. read more

INTERESTING STUFF – 13 September 2014

2 days agoHealth / Aging : Time Goes By

ELDERS REACT TO 50 SHADES OF GREY MOVIE TRAILER Have you read the 50 Shades of Gray books? I haven't but there has been so much talk that I certainly know the general idea. In this video, the “Elder React...

Near Term Outcomes in Healthcare Costs Resulting from Piecemeal Progress Towards a Cure for Aging

3 days agoHealth / Aging : Fight Aging

The cure for aging is often naively envisaged as a single treatment, but this won't be the case in reality. Aging is caused by a variety of distinct parallel processes all running at the same time, producing forms of damage that accumulate in and between cells. Show More Summary

Kicking the Bucket List

3 days agoHealth / Aging : Time Goes By

I stole that title from a blog post at The New Yorker this week because it perfectly expresses my sentiments on the topic. I didn't like the 2007 movie and even more, I dislike the cultural adoption of the idea...

Considering Intracellular Amyloid Beta in Alzheimer's Disease

3 days agoHealth / Aging : Fight Aging

There is a growing diversity of views in the Alzheimer's research community regarding mechanisms and future directions, which is probably to be expected given the slow path to results on the consensus approach of removing amyloid ?.Show More Summary

Recent Work on SkQ1 and Vascular Inflammation

3 days agoHealth / Aging : Fight Aging

SkQ1 is a mitochondrially targeted antioxidant, and there is evidence to show that it can modestly extend life in mice. Mitochondria are important in the aging process, and one of the ways in which they interact with surrounding cell biology is by generating damaging reactive oxygen species (ROS). Show More Summary

Inducing Heat Shock Protein 70 as a Basis for Therapies

4 days agoHealth / Aging : Fight Aging

Most research into intervening in the aging process is focused on slowing aging. It is a search for ways to safely alter metabolism in order to reduce the rate at which unrepaired cellular and molecular damage accumulates. This damage...Show More Summary

Still Learning from Our Parents

4 days agoHealth / Aging : Time Goes By

There was no wiggle room with my dad. When I was a kid, if my chores were left undone, if my bed was not made just so, if I was late for anything or if there was a grade below...

A Clinical Trial of Induced Pluripotent Stem Cells for Macular Degeneration

4 days agoHealth / Aging : Fight Aging

Induced pluripotent stem (iPS) cells have been moving towards practical use in medicine quite rapidly since their discovery eight years ago, and here researchers will run a first test in a human patient: A Japanese patient with a debilitating eye disease is about to become the first person to be treated with induced pluripotent stem cells. Show More Summary

Getting Closer to Type 2 Diabetes Raises Cancer Risk

4 days agoHealth / Aging : Fight Aging

Type 2 diabetes is for the majority of sufferers a self-inflicted problem. It is usually a consequence of becoming fat and sedentary: if you avoid both of those, then it is unlikely to happen to you. Even in the comparatively late stages...Show More Summary

"When Google is throwing $100 million at aging research, why fund SENS?"

5 days agoHealth / Aging : Fight Aging

There is an art to writing press releases for large joint ventures, and one part of it involves setting out the largest number you can vaguely justify in terms of dollars that will be spent in the future. You can look at the recent joint...Show More Summary

Internet Advertising and My Brain Health

5 days agoHealth / Aging : Time Goes By

Today is Net Neutrality Day and thousands of websites have joined together in a brief slowdown of the loading of their pages to point out what will happen if the FCC decides to create paid internet “fast lanes” for big...

Applying Targeting Mechanisms to Stem Cell Therapy

5 days agoHealth / Aging : Fight Aging

The cancer research community has developed a wide range of mechanisms that can be used to more accurately target a delivered therapy to specific locations in the body or specific types of cell. Many of these methods are largely independent...Show More Summary

"Why am I waiting to do something about this?"

5 days agoHealth / Aging : Fight Aging

Here is a little more context for yesterday's launch of the Palo Alto Longevity Prize. Like myself all of the regular readers of Fight Aging! had an awakening at some point in time, a moment in which we suddenly realized that aging could and should be cured with future advances in medicine. Show More Summary

Are You the Type to Make Your Partner Jealous?

Jealousy is one of the most unpleasant emotions we can experience. For some people, however, jealousy becomes a tool they use to manipulate their partners. Find out if you- or your partner- are the jealousy-inducing type with this 18-item quiz. read more

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