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Progress in Understanding Plant Longevity is Interesting, But is it in Any Way Relevant?

11 hours agoHealth / Aging : Fight Aging

There is a portion of the life science community interested in the longevity of plants, though it is fairly disconnected from research into medicine and aging for the animal half of the planet. We can debate whether or not there is anything...Show More Summary

Avoiding Weight Gain Across the Whole Lifespan Correlates with a Lower Mortality Rate

23 hours agoHealth / Aging : Fight Aging

Research from the past few years has demonstrated that far better correlations between weight and mortality can be obtained by considering the history of individual weight rather than just taking snapshots of populations at a moment in time. Show More Summary

AUTEN-67 as an Example of an Autophagy-Enhancing Drug Candidate

23 hours agoHealth / Aging : Fight Aging

For more than a decade there has been some interest in the research community in developing treatments based on enhancing the cellular maintenance processes of autophagy. Higher levels of autophagy feature in many of the established animal lineages with modestly extended healthy longevity, created through genetic manipulation. Show More Summary

Inhibition of Mitochondrial Complex I Extends Life in Killifish and Zebrafish

yesterdayHealth / Aging : Fight Aging

In the open access paper linked below, researchers demonstrate modest life extension in the short-lived killifish and zebrafish species by inhibiting a specific portion of the protein machinery inside mitochondria, the power plants of...Show More Summary

HSP27 Attenuates Cardiac Aging in Mice

yesterdayHealth / Aging : Fight Aging

The various heat shock proteins play a role in the hormetic response to damage. When damaged, cells dial up their repair activities for a while, and if the damage is mild and brief, the result is a net gain in quality control. Less damage...Show More Summary

Macrophages Repair Broken Capillaries in the Brain

yesterdayHealth / Aging : Fight Aging

Here researchers investigate how immune cells in the brain work to fix tiny breakages of blood vessels. The link between vascular aging and neurodegeneration is most likely largely driven by breakage of blood vessels in the brain. Increased...Show More Summary

“About” Taking a Day Off

Life has intruded and for a day or two I need take a short break from writing that requires actual thought. So here are a couple of things that won't tax my brain and I hope will amuse you. PIGS...

Views of the Cost and Time Required to Build an Organ Engineering Industry

2 days agoHealth / Aging : Fight Aging

Below find linked an open access paper that looks at what has to be done to reach the goal of engineered patient-matched organs, built as needed for transplantation, and the resulting end to shortages and waiting lists. It is interesting for putting some figures on the table for time and cost for the various lines of development required. Show More Summary

How Time Can Bring You and Your Partner Even Closer

Conflict in relationships is often a situation people try their best to avoid. The more time you spend trying to work it through, the more it may actually increase your intimacy.

3 Ways to Predict a Partner May Be Unfaithful

A partner who is faithful, all other things being equal, is one who will make you happier. This 3-part checklist will help you spot the danger signs.

Give Your Relationship Some Time to Make it a Better One

Conflict in relationships is often a situation people try their best to avoid. The more time you spend trying to work it through, the more it may actually increase your intimacy.

The Surprising Psychology of Baby Naming

Your name was, in all likelihood, selected by your parents and you, in turn, will select names for the kids you decide to have. Here's what might influence that decision

Do You Know Which Buttons to Push With Your Partner?

Conflict in relationships is often a situation people try their best to avoid. The more time you spend trying to work it through, the more it may actually increase your intimacy.

A Sedentary Lifestyle Correlates with Greater Calcification of Heart Tissue

2 days agoHealth / Aging : Fight Aging

In recent years human studies of exercise and life expectancy have pointed to a correlation between time spent sedentary and mortality rate, and this correlation appears to be independent of the level of regular exercise undertaken. Here researchers look to calcification as a possible mechanism to explain this association. Show More Summary

Calorie Restriction Improves Quality of Life in Human Practitioners

2 days agoHealth / Aging : Fight Aging

Researchers have published an interesting set of results from one of a number of human studies of moderate calorie restriction that have taken place over the past decade. Reduced calorie intake has a beneficial effect on long-term health,...Show More Summary

ABT-737 is Another New Senolytic Drug Candidate, Working via BCL-W, BCL-XL, and Induced Apoptosis

3 days agoHealth / Aging : Fight Aging

Senolytic therapies are those that cause senescent cells to die while causing minimal side-effects. Developing methods to selectively destroy senescent cells has been on the SENS rejuvenation research agenda for going on fifteen years,...Show More Summary

Attempting to Extract Causation from the Correlation Between Retirement Age and Life Expectancy

4 days agoHealth / Aging : Fight Aging

Researchers here make an attempt to extract some insight into causation from longitudinal data on retirement age and subsequent mortality rates. If continuing to work on balance involves undertaking more physical activity than wouldShow More Summary

The Importance of Lysosomes in Aging and Longevity

4 days agoHealth / Aging : Fight Aging

The lysosome is a type of cellular component that serves as a recycling unit, breaking down unwanted proteins and structures into their raw materials. As such they play an important role in cellular housekeeping, the removal of damaged structures, machinery, and waste that will, if left unchecked, harm cells and cellular processes. Show More Summary

A Surprising Media Respect For an Elder

4 days agoHealth / Aging : Time Goes By

Ageist language isn't confined to such obvious demeaning labels as geezer, coot, biddy, etc. - or to “elderspeak,” the belittling forms of address such a “dearie,” and “sweetie” or speaking to old poople in a loud, slow voice. Much more...

Fight Aging! Newsletter, May 2nd 2016

4 days agoHealth / Aging : Fight Aging

FIGHT AGING! NEWSLETTER May 2nd 2016 Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent...Show More Summary

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