The immune system is a very efficient mechanism for certain types of task, if it can just be harnessed and put to work. Left to its own devices throughout most of a life span it can effectively destroy misbehaving cells, remove some types of harmful protein aggregates, and of course defend against self-replicating invaders of many different types. Show More Summary
I grew up in suburban Oregon and California so I had a good deal of experience with suburban living before I moved here to Lake Oswego, Oregon, four years ago. I also lived for 40 years in New York City...
There is a distinction to be drawn between primary and secondary aging, which at this time we might consider as the division between the things you can't yet do anything about on the one hand versus the things can you do something about on the other. Show More Summary
Chronic inflammation increases with aging due to a progressive dysfunction of the immune system: it is overactive but yet ineffective, like a failing engine running hot. Inflammation is a necessary part of the immune response, but if...Show More Summary
This Sunday Elder Music column was launched in December of 2008. By May of the following year, one commenter, Peter Tibbles, had added so much knowledge and value to my poor attempts at musical presentations that I asked him to...
If you don't want to look socially introverted, you may want to remove those earphones you're wearing. Although you may enjoy the entertainment our mobile devices provide as they provide a soundtrack to our day, you may also be sending unintentional cues telling other people to stay away. read more
ELDERS REACT TO 50 SHADES OF GREY MOVIE TRAILER Have you read the 50 Shades of Gray books? I haven't but there has been so much talk that I certainly know the general idea. In this video, the “Elder React...
The cure for aging is often naively envisaged as a single treatment, but this won't be the case in reality. Aging is caused by a variety of distinct parallel processes all running at the same time, producing forms of damage that accumulate in and between cells. Show More Summary
I stole that title from a blog post at The New Yorker this week because it perfectly expresses my sentiments on the topic. I didn't like the 2007 movie and even more, I dislike the cultural adoption of the idea...
There is a growing diversity of views in the Alzheimer's research community regarding mechanisms and future directions, which is probably to be expected given the slow path to results on the consensus approach of removing amyloid ?.Show More Summary
SkQ1 is a mitochondrially targeted antioxidant, and there is evidence to show that it can modestly extend life in mice. Mitochondria are important in the aging process, and one of the ways in which they interact with surrounding cell biology is by generating damaging reactive oxygen species (ROS). Show More Summary
Most research into intervening in the aging process is focused on slowing aging. It is a search for ways to safely alter metabolism in order to reduce the rate at which unrepaired cellular and molecular damage accumulates. This damage...Show More Summary
There was no wiggle room with my dad. When I was a kid, if my chores were left undone, if my bed was not made just so, if I was late for anything or if there was a grade below...
Induced pluripotent stem (iPS) cells have been moving towards practical use in medicine quite rapidly since their discovery eight years ago, and here researchers will run a first test in a human patient: A Japanese patient with a debilitating eye disease is about to become the first person to be treated with induced pluripotent stem cells. Show More Summary
Type 2 diabetes is for the majority of sufferers a self-inflicted problem. It is usually a consequence of becoming fat and sedentary: if you avoid both of those, then it is unlikely to happen to you. Even in the comparatively late stages...Show More Summary
There is an art to writing press releases for large joint ventures, and one part of it involves setting out the largest number you can vaguely justify in terms of dollars that will be spent in the future. You can look at the recent joint...Show More Summary
Today is Net Neutrality Day and thousands of websites have joined together in a brief slowdown of the loading of their pages to point out what will happen if the FCC decides to create paid internet “fast lanes” for big...
The cancer research community has developed a wide range of mechanisms that can be used to more accurately target a delivered therapy to specific locations in the body or specific types of cell. Many of these methods are largely independent...Show More Summary
Here is a little more context for yesterday's launch of the Palo Alto Longevity Prize. Like myself all of the regular readers of Fight Aging! had an awakening at some point in time, a moment in which we suddenly realized that aging could and should be cured with future advances in medicine. Show More Summary
Jealousy is one of the most unpleasant emotions we can experience. For some people, however, jealousy becomes a tool they use to manipulate their partners. Find out if you- or your partner- are the jealousy-inducing type with this 18-item quiz. read more