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Use of a Fasting-Mimicking Diet to Attenuate Progression of Multiple Sclerosis

5 hours agoHealth / Aging : Fight Aging

Valter Longo's research group has for the past few years been gathering data in clinical trials on the effects of a short-term low-calorie diet that achieves enough of the benefits of fasting to be useful. In essence the researchersShow More Summary

Nanoparticles to Target Atherosclerotic Plaques

5 hours agoHealth / Aging : Fight Aging

This popular science article takes a look at efforts to develop nanoparticles capable of reducing the size of plaques in blood vessels produced by the processes of atherosclerosis. These plaques narrow and deform blood vessels, ultimately breaking apart to cause blockages and ruptures of blood vessels that are often fatal. Show More Summary

The Use of Stem Cell Therapies to Treat Osteoarthritis

22 hours agoHealth / Aging : Fight Aging

Today I'll point out a review paper that covers a few approaches to stem cell therapy in the context of treating osteoarthritis, a degenerative condition of the joints. Arguably the most demonstrably successful branch of stem cell medicine...Show More Summary

Memorial Day 2016

Today, we honor the men and women who have died while serving in America's armed forces. Today, there will be parades in thousands of cities and towns throughout the country. Today, there will also be the annual National Memorial Da...

Reviewing What is Known of FGF23 and Klotho Signaling in Aging

yesterdayHealth / Aging : Fight Aging

In past years researchers have demonstrated in animal studies that reduced levels of klotho can shorten life span while increased levels modestly extend life span. The underlying mechanisms are complex and not fully understood. As is...Show More Summary

Telomere Length Suggested as the Mechanism Limiting Heart Regeneration

yesterdayHealth / Aging : Fight Aging

Evolution has left mammals with only a limited ability to regenerate heart tissue. Unlike very regenerative species such as salamanders or zebrafish, we lose most of our ability to heal the heart very early in life. Here, researchers...Show More Summary

Are You Flirting More Than You Realize?

Whether or not you intend to, you may be sending out signals that you’re sexually available. See which of the 5 flirting types fits your own behavior.

Fight Aging! Newsletter, May 30th 2016

2 days agoHealth / Aging : Fight Aging

FIGHT AGING! NEWSLETTER May 30th 2016 Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent...Show More Summary


3 days agoHealth / Aging : Time Goes By

MAN DRIVES SAME CAR FOR 77 YEARS It was a happy day for me when, having moved to New York City in early 1969, I could sell the car. It didn't please me when I left Manhattan and needed a...

Disruptive Change in Aging Research Arrives from the Outside

3 days agoHealth / Aging : Fight Aging

Disruption is a part of progress. All communities of research and development go through cycles in which (a) the established mainstream and its insiders become slow and ineffective, (b) outsiders become frustrated given the unrealized...Show More Summary

10 Ways to Know That It's Time to Go

Sometimes it's hard know when it’s time to leave. These 10 tips will help you figure out the best way to make an exit.

Expectations Versus Reality About Old Age

4 days agoHealth / Aging : Time Goes By

Not too long ago, my Canadian blog friend, doctafil, emailed a story from the Montreal Gazette that contained a lot of statistics and information about how people are growing old in Canada. The serendipity is that it arrived when I....

Tinkering with Sensory Pathways as an Approach to the Development of Calorie Restriction Mimetics

4 days agoHealth / Aging : Fight Aging

Most laboratory species - such as flies, worms, mice, and other mammals - have been shown to age somewhat more slowly in response to calorie restriction; it changes near every measure of metabolism and improves near every measure of health. Show More Summary

DNA Damage as an Important Determinant of Vascular Aging

4 days agoHealth / Aging : Fight Aging

The authors of this paper argue that stochastic mutational damage to nuclear DNA is important in the progression of vascular aging, the declining function and structural integrity of blood vessels. It is more or less the consensus hypothesis...Show More Summary

Borrowed Immune Cells to Fight Cancer

4 days agoHealth / Aging : Fight Aging

It is an unfortunate fact of life that many promising avenues of medical research languish partially developed and unfunded. It isn't unusual to see potentially transformative medical technologies linger with little further progress for a decade or more after their first triumphant discovery. Show More Summary

The Best Way to Move on After a Breakup

Getting over the end of your relationship can be a difficult process, but finding the silver lining will help you move on.

The Possibility of Reducing Amyloid in the Brain by Reducing it Elsewhere

5 days agoHealth / Aging : Fight Aging

This paper explores the mechanisms by which the amyloid associated with the progression of Alzheimer's disease can be cleared naturally outside the brain. It raises the possibility that finding ways to reduce amyloid outside the brain will allow existing transport and clearance mechanisms to export and remove more of the amyloid from the brain. Show More Summary

Arguing for More and Better Studies of the Comparative Biology of Aging

5 days agoHealth / Aging : Fight Aging

In this open access paper, the author argues for greater investigation of the fundamentals of aging in various species, for more comparisons of the biochemistry of aging between wild and laboratory populations, and for greater collaboration...Show More Summary

When Looking at Stem Cell Activity, Even Short-Lived Sea Urchins Appear to be Negligibly Senescent

5 days agoHealth / Aging : Fight Aging

The paper I'll share today takes a look at stem cells over the course of aging in different sea urchin species that exhibit radically different life spans, ranging from a few years to somewhere north of a century. A fair number of marine...Show More Summary

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