THE ONLY KNOWN FOOTAGE OF ANNE FRANK It's grainy, black-and-white shot on 22 July 1941, but you know immediately that it is Anne Frank. She is leaning out of the second-floor window of her home in Amsterdam watching a bride...
The internet has not been kind to bookstores especially the small independents that have played such an important part of communities for at least a couple of hundred of years and are such a pleasure to visit. Two I know...
It's always good to listen to viewpoints that you happen to disagree with. This is why I pay attention to research strategies and researchers informed by programmed aging theories such as the hyperfunction hypothesis that builds on antagonistic pleiotropy. Show More Summary
This is a good example of first generation cell therapies that have been available via medical tourism for quite some time, with enough information available for patients to make an informed decision about use, but are only now working...Show More Summary
It is always going to be easier to develop treatments for non-vital organs, and in some cases work on cell therapies for those organs can be simpler and less costly for other, unrelated reasons. Thus progress is faster in these areas,...Show More Summary
Readers sometimes send me interesting questions about getting old (as if you think I actually have answers). When they are specific and about topics on which there is a body of knowledge and consensus from experts, I can act as...
Icebreakers are a traditional way to overcome the original awkwardness that many people feel when they first form a group. Whether it’s with a class, a set of co-workers, or a volunteer committee, a little psychology will go a long way toward building group cohesion and identity.
The varied approaches to research developed over past decades by the aging research community are driven by two things: firstly that we live for a long time, and secondly the absence of a way to accurately determine an individual's biological age. Show More Summary
Aging is accumulated cell and tissue damage, and the slow growth of healthy human life expectancy that has taken place over the past two centuries thus reflects a lesser load of a damage present in individuals of a given age. The old...Show More Summary
The available evidence from animal studies shows that lack of exercise causes poor health and a shorter life expectancy, while moderate regular exercise causes better health and a longer life expectancy. In humans the data can largely only show correlations rather than cause and effect, but the same pattern emerges. Show More Summary
Élie Metchnikoff was a noted figure in the first days of modern immunology at the close of the 19th century. He is credited with coining the term gerontology for the study of aging. Members of the energetic European grassroots community of longevity advocates have recently proposed to celebrate Metchnikoff's anniversary each year. Show More Summary
We live in an era of very rapid change driven by technological progress. Today's world is enormously different from that of three or four decades past: consider the pervasive effects of the revolution in communications and computing technologies that has taken place over that time. Show More Summary
When I was a kid, old people regularly annoyed me with a mantra they used as a catchall comment to discussions of even the mildest difficulties: “As long as you've got your health.” they repeated. “As long as you've got...
Age-related macular degeneration has a fairly direct relationship to the accumulation of a mix of metabolic wastes called lipofuscin in long-lived retinal cells. There are other contributing causes, but that is an important one. Cell...Show More Summary
The development of fairly consistent, accurate means to measure biological age - as opposed to chronological age - from a tissue sample is an important thread in aging research. Aging is a process of damage accumulation, and rejuvenation would be achieved through damage repair. Show More Summary
As you make your way through life, you are guided by both the long- and short-term goals you’ve set for yourself. However, your plans may take an unexpected turn. From research on “career shocks,” you can learn to manage the unexpectedly good and bad that life throws your way whether in your career or your relationships.
It is known that cellular repair processes are important in the determination of life span. Many of the methods of modestly slowing aging in laboratory species are accompanied by increased rates of cellular housekeeping, the recycling of damaged proteins and cell components. Show More Summary
Cryonics is the low-temperature preservation of the deceased in order to grant them a chance at a renewed life when technologies for restoration are developed. One of the big outstanding questions is the degree to which cryopreservation successfully preserves the fine structure of the brain and thus the data of the mind. Show More Summary
There are a lot of theories of aging. Simply outlining the numerous categories of theory and offering a few comments as to which of the better known theories are currently well supported, dead, or disputed is a fairly detailed undertaking. Show More Summary
Hsp22 is a heat shock protein in the fly genome. Like other heat shock proteins it is involved in hormesis, wherein cells repair themselves more aggressively in response to heat, toxins, and other forms of stress. If the stress is mild or short-lived then the result is a net reduction in cellular damage. Show More Summary