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Linking Inflammation, Immune Dsyfunction, and Intestinal Aging

3 hours agoHealth / Aging : Fight Aging

Today I noticed a set of interesting research materials in which the authors report on their investigation of links between chronic inflammation and intestinal dysfunction in aging. Growing inflammation is characteristic of aging in an age in which near everyone puts on a great deal of weight as they get older. Show More Summary

New guidelines could help improve research into vascular cognitive impairment

New guidelines have been developed that it is hoped will help to progress research into vascular cognitive impairment following a study that brought together the views of over 150 researchers in 27 countries.

6 Ways to Stand Out From the Crowd

Going along with the crowd seems to be our default mode, as supported by recent neuroscience research. These six tips will give you the skills to stand out.

More Investigation of the 5q33.3 Locus in Human Longevity

13 hours agoHealth / Aging : Fight Aging

The search for gene variants associated with human longevity has turned up only two reliable correlations to date, with a couple more in the tentative bucket awaiting further confirmation. The effects of all of these are not large; individually, each represents only a small increase in the odds of a longer life. Show More Summary

Aging as the Evolutionary Cost of Complexity, Driven by Mitochondrial Dynamics

13 hours agoHealth / Aging : Fight Aging

This popular science article walks through a new interpretation of one class of evolutionary theory of aging, envisaging the existence of aging as being necessary for the formation of complex life forms with active metabolism and high energy demands. Show More Summary

The First Sneak Attack on Medicare, Social Security Has Already Happened

13 hours agoHealth / Aging : Time Goes By

And we didn't even know it. Remember, back on the morning of 3 January when the new 115th Congress convened, Republicans had already voted in secret the night before to shut down the Office of Congressional Ethics (OCE)? And how,...

The Latest Analysis of Calorie Restriction in Primates: Benefits to Health and Longevity

yesterdayHealth / Aging : Fight Aging

The latest analysis of data on primate longevity under conditions of calorie restriction was published today, and sides with the claims of extended longevity and improved health made a few years ago. Two long-running studies of calorie...Show More Summary

How to Listen with All Four of Your Ears

We typically think of communication in terms of the two channels of verbal and nonverbal behavior. New research shows how our 4 ears can get tuned in under the right conditions.

Towards a Better Understanding of the Effects of Tiny Strokes on Cognitive Decline

yesterdayHealth / Aging : Fight Aging

In recent years it has become clear that we all suffer many tiny, unnoticed strokes as we age. These involve the rupture or blockage of small blood vessels in the brain and resulting damage and cell death in a very small area of tissue. Show More Summary

A Delicious TGB Extra

Time Goes By does not usually publish on Tuesday but this is too delicious to hold back especially because it does have a sell-by date - Friday 20 January – after which it is not as rich. It happened Sunday...

VCAM1 as a Potential Harmful Signal in Old Blood

yesterdayHealth / Aging : Fight Aging

Heterochronic parabiosis, linking the circulatory systems of an old and a young mouse, benefits the old mouse in that it reduces some measures of aging. Researchers initially focused on possible beneficial signals in young tissues and...Show More Summary

Persistent infection keeps immune memory sharp, leading to long-term protection

For many infectious diseases, a single bout of the illness protects a person against contracting it again. Sometimes, the infecting microbe persists in the body long after symptoms resolve. Now, researchers studying the tropical parasite...Show More Summary

Considering Pan-mTOR Inhibitors as Alternatives to Rapamycin

2 days agoHealth / Aging : Fight Aging

For a number of years now, mechanistic target of rapamycin (mTOR) has been the focus of a fair amount of research into aging. Goals include gaining a better understanding of the way in which metabolism determines natural variations in...Show More Summary

A Profile of Craig Venter and Human Longevity Inc.

2 days agoHealth / Aging : Fight Aging

Despite all the publicity, Human Longevity Inc. is a personalized medicine company rather than a longevity science company, intended to be the seed for a new industry that provides an incremental advance on present day customization of medicine through use of genetics. Show More Summary

Fitness in Older Adults Correlates with Improved Brain Activity and Memory

2 days agoHealth / Aging : Fight Aging

Researchers here add more data to the known correlations between specific measures of fitness and cognitive function in later life. There are any number of potential mechanisms linked to exercise that might explain a slower age-related...Show More Summary

How Do You Want to Live the Rest of Your Life?

2 days agoHealth / Aging : Time Goes By

EDITORIAL NOTE: Here is an old-fashioned word for you: nonplussed (to be surprised and confused so much that you are unsure how to react). That's how I feel. There is such a gigantic amount to be said following the nominee...

Fight Aging! Newsletter, January 16th 2017

3 days agoHealth / Aging : Fight Aging

Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and...Show More Summary


3 days agoHealth / Aging : Time Goes By

(You will find Part 1 of Toes Up here.) This Sunday Elder Music column was launched in December of 2008. By May of the following year, one commenter, Peter Tibbles, had added so much knowledge and value to my poor...

Will Senescent Cell Clearance Therapies Sink the Pensions and Annuities Industry?

4 days agoHealth / Aging : Fight Aging

The annuities and pensions industries, private and public, include some of the largest of all financial institutions. Collectively they are enormous, representing a staggering amount of money under management. To simplify a complex picture greatly, most of these programs take the form of a wager against longevity. Show More Summary

INTERESTING STUFF – 14 January 2017

4 days agoHealth / Aging : Time Goes By

SOMETHING SPECIAL HAPPENED AT THE SUPERMARKET Between an old person and a four-year-old kid. MY GOD, I WILL MISS BARACK AND MICHELLE OBAMA On 6 January at the White House, Michelle Obama gave gave her final speech as First Lady....

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