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An Interview with Bob Hariri of Human Longevity, Inc.

5 hours agoHealth / Aging : Fight Aging

Bob Hariri is a cofounder of Human Longevity, Inc., the present exemplar of the mainstream focus on genetics when it comes to aging and longevity. I've had my say as to why I think this sort of effort is likely only to incrementally improve the present state of medicine rather than actually deliver meaningful extension of healthy life. Show More Summary

Unlock the Car Door With Your Mind

15 hours agoHealth / Aging : Time Goes By

It's amazing what you can find on the internet. Sometimes I need to closely monitor myself so not to fall down a rabbit hole only to awaken as from a dream two hours later, my mind full of way too...

An Update on Reprogramming Glial Cells into Neurons

15 hours agoHealth / Aging : Fight Aging

Neuroglia are a variety of of types of support cell in the brain and nervous system. They perform all sorts of necessary tasks, some of which are still being uncovered, such as the recent discovery that recycling of damaged mitochondria in long axons is delegated to astrocyte glial cells rather than being performed by the nerve cell owning the axon. Show More Summary

Atherosclerosis Correlates with Cognitive Impairment

16 hours agoHealth / Aging : Fight Aging

Aging is a global phenomenon of damage accumulation throughout the body. Different people age at modestly different rates due to their lifestyle choices and environment, so correlations between different manifestations of the aging process...Show More Summary

Not Everyone Likes Mitochondrial DNA Damage as a Theory of Aging

yesterdayHealth / Aging : Fight Aging

There are factions within the research community who argue against mitochondrial DNA damage as an important cause of aging. That said, I think I could pick any present hypothesis on the biochemistry of aging and find a faction whose members don't think much of it. Show More Summary

5 Questions that Will Test Your Sense of Meaning in Life

The need to find meaning in your life might not be something you ponder on a daily basis but it lies at the root of your sense of worth. By answering these 5 questions, you can measure your progress toward that ultimate source of happiness. read more

An Antidote for JOWS

End-of-year holidays now last for four months, 120 days from September through December. There is no escaping them and each reaches its peak of frenzy during the week in which it falls – this week, for one example. Potential blog...

Initial Evidence for Glycogen Buildup in the Brain to Contribute to Aging

yesterdayHealth / Aging : Fight Aging

This research suggests another type of metabolic waste should be added to those already known to contribute to degenerative aging. Given where the researchers presently stand, one logical next step might be to run mouse life span studies...Show More Summary

Lysosomal Dysfunction in Atherosclerosis

yesterdayHealth / Aging : Fight Aging

Atherosclerosis is the build up of fatty plaques known as atheromas in blood vessel walls, leading to death or injury when blood vessels suffer structural failure or part of a plaque breaks loose to block a blood vessel elsewhere. Plaques...Show More Summary

Experimentation in Regenerative Reprogramming

2 days agoHealth / Aging : Fight Aging

Salamanders and zebrafish are among the species that can regenerate limbs and even large portions of vital organs after injury, and the regrown portions of their anatomy are just the same as the original. We mammals cannot do this: we can manage fingernails, occasionally fingertips at a very early age, and portions of the liver, but that is about it. Show More Summary

Investigating Nail Stem Cells

2 days agoHealth / Aging : Fight Aging

Nails are one of the few parts of the human body that can regenerate completely after loss in adults. So why not dig deeper into the biology of the stem cells involved? Perhaps it will teach us something more about why only a few types of mammalian tissue are capable of such complete regeneration. Show More Summary

Restoring Function to Old Pancreatic Islets

2 days agoHealth / Aging : Fight Aging

Researchers here transplant pancreatic islets from old to young mice and see restored function. They conclude that replacing the microvasculature that supplies blood to the tissue is the important change in this process, but I suspect...Show More Summary

Elder Surveillance For Their Own Good

2 days agoHealth / Aging : Time Goes By

Okay, they usually call it “monitoring” instead of surveillance to sound less Orwellian but don't be fooled - it is surveillance. It's not quite here yet but the groundswell is increasing as commercial development and science research projects in Japan,...

What Lonely People Seek from Facebook

Critics of social media argue that people who spend time on Facebook become social introverts due to their reliance on virtual rather than face-to-face interactions. However, a closer look at the research reveals that loneliness is the cause, not the result, of heavy Facebook use. read more

INTERESTING STUFF – 22 November 2014

4 days agoHealth / Aging : Time Goes By

“DEAD” WOMAN WAKES IN MORGUE REFRIGERATOR Back in the 1950s, there was a chilling and deservedly famous Alfred Hitchcock Presents TV episode about a man, played by Joseph Cotton, so paralyzed in an accident that the coroner believes he is...

Why Do We Advocate for Rejuvenation Research?

5 days agoHealth / Aging : Fight Aging

Yesterday, I had occasion to spend six hours or so in the emergency room of a medical center largely focused on treating serious conditions that are most prevalent in old people. A part of that experience by necessity involved listening to the comings, goings, and conversations of those present. Show More Summary

Why We Fantasize About Other Partners

When partners in a long-term relationship have fantasies of infidelity, is this the same as actual cheating? It’s possible to be unfaithful in fantasy and still have a rewarding and fulfilling relationship, as long as you understand the origins of your fantasies. They may even benefit your relationship. read more

The Gift of Freedom in the Third Act of Life

5 days agoHealth / Aging : Time Goes By

”I’ve learned my lines. The house lights have dimmed and I’ve just walked center stage for the third act of the play I started writing long ago. And within the physical, economic and intellectual framework of being an 'old guy,'...

Lamin-B and Immunosenescence

5 days agoHealth / Aging : Fight Aging

The aging of the immune system isn't just a matter of damage, it is also inherent in the structure of a limited number of immune cells over time becoming ever more devoted to remembering threats rather than fighting them. As this research...Show More Summary

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