Data on the degree to which various age-related conditions contribute to mortality is actually a lot less precise than most people assume it to be. Cause of death in old age is often either ambiguous or ambiguously recorded, leading to the need for estimation and correction via statistical methods. Show More Summary
Recently, I ran across a quotation from Muriel Spark on the subject of growing old: ”Being over 70 is like being engaged in a war. All our friends are going or gone and we survive amongst the dead and the...
Researchers review the evidence from animal studies suggesting that stem cell transplants are a beneficial treatment for degenerative disc disease. This is a treatment that has been available via medical tourism for some years now, though...Show More Summary
This Sunday Elder Music column was launched in December of 2008. By May of the following year, one commenter, Peter Tibbles, had added so much knowledge and value to my poor attempts at musical presentations that I asked him to...
First impressions count almost more than any other aspect of our nonverbal behavior. Managing your own can prove vital in every aspect of your daily life from your social encounters to your romantic relationships. These 8 tips will ensure that your entrances will be both grand and great. read more
OSCAR WINNER: THE LADY IN NUMBER 6 For the past two Saturdays, the documentary about the 110-year-old pianist who was also the oldest Holocaust survivor was featured in this first spot on the list. So it makes sense that today...
The immune system becomes unruly and ineffective in old age: on the one hand it generates ever greater levels of harmful chronic inflammation, while on the other it no longer has a sufficient population of effective cells able to tackle new threats, scan for cancerous cells, and eliminate senescent cells from the body. Show More Summary
Last week, the Guardian published the results of a survey the newspaper had conducted about aging. It appears the U.K. government hasn't done any better preparing for the big demographic shift to an older population than the U.S. government has....
The prevailing wisdom is that the introduction of effective means to treat aging will reduce health care costs. After all, most expenditures are generated in the final stages of life, during the expensive and eventually futile process of trying to prevent the failure of constantly near-failing organs and systems. Show More Summary
A small but significant number of cells become overtaken by damaged, dysfunctional mitochondria over a lifetime, and this process is one of the contributing causes of degenerative aging. Mitochondria are important to many cellular processes, and quality control mechanisms aim to either repair damage or remove and replace damaged mitochondria. Show More Summary
I had just yesterday mentioned one of the ventures that researcher Alex Zhavoronkov is involved in, and today I hear that he and a team are launching In Silico Medicine in the US. No doubt the announcement was pushed forward to benefit...Show More Summary
TGB reader chlost, who blogs at Just My Life, sent this video that in a kneejerk manner of many years at doing this, I bookmarked for Saturday's Interesting Stuff list. But it kept pulling me back so I watched it...
These researchers propose that declining proteostasis with aging is something that starts abruptly in nematode worms, which they take as evidence for programmed aging - such as perhaps a coordinated lapse or other unfavorable changeShow More Summary
This review looks over progress in the use of stem cells treatments as a way to impact chronic inflammation and treat non-healing wounds: A chronic wound develops when a wound fails to heal within an expected time frame and fails to achieve functional closure. Show More Summary
In a better world, the US research community would receive the same level of comparatively enthusiastic and well-informed public support for longevity science that is seen in Russia, while the Russian research community would enjoy the same greater level of access to funding as is found in the US. Show More Summary
I don't think it is an overstatement to say that cataract surgery is a modern medical miracle. That said, there is some archaeological evidence that as far back as ancient Rome, surgery may have been performed to treat cataracts. Yeah,...
Mitochondria are bacteria-like organelles inside our cells tasked with the production of chemical energy stores, among other tasks. Like all organelles their collection of intricate protein machinery is wrapped by a membrane - or rather two membranes in this case, inner and outer. Show More Summary
This open access study has something for everyone to argue about, no matter your previous position on diet and health. The basic idea that lower dietary protein levels are beneficial and increase life expectancy is straightforward and supported by research on calorie restriction and methionine restriction. Show More Summary
Technological progress happens in waves, and this is just as much the case in longevity science as elsewhere. Ideas spread within a community, and are acted upon by diverse groups around the same time. Funding is found, companies and laboratories are established, work is accomplished across a few years, and in the course of that new ideas arise. Show More Summary
A new theory of long-term committed relationships proposes that the ability to seek self-expression predicts the greatest chances of its success. The process of achieving self-expression may make the stakes higher, but the potential rewards much more satisfying in the long term. read more