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Kelsey Moody on Antoxerene and the Near Future of Applied Aging Research

11 hours agoHealth / Aging : Fight Aging

Antoxerene formally launched today, concurrently with a $1.5 million funding round, a spin-off venture of Ichor Therapeutics. I recently had the chance to ask Kelsey Moody at Ichor Therapeutics a few questions on the new lines of work...Show More Summary

Genetic mutation encourages longevity in men

A mutation in the gene for the growth hormone receptor promotes longevity, increasing men's lifespan by an average of 10 years, scientists have discovered.

Changes in Microvesicles as a Potential Marker of Cellular Senescence

19 hours agoHealth / Aging : Fight Aging

One of the ways in which cells communicate and react to one another is via vesicles, small membrane-wrapped packets of proteins. Cell signaling in general is an important part of the detrimental effects of senescent cells on tissue function...Show More Summary

Are Children an Elder Hazard?

20 hours agoHealth / Aging : Time Goes By

In the nature of callow youth, when I was a teenager - and maybe a young woman too - I noted with some disdain that the homes of old people I knew were often in need of a design update....

Starting in on the Identification of Mechanisms by which Gut Bacteria Influence Aging

20 hours agoHealth / Aging : Fight Aging

It is now fairly well established that gut bacteria have a degree of influence on the pace of aging, though just how much of individual variation can be explained in this way is still a question mark. The next step in the process of investigation is to identify the most significant mechanisms involved. Show More Summary

Venture Funds for Longevity Science: an Interview with Laura Deming

yesterdayHealth / Aging : Fight Aging

Laura Deming runs the Longevity Fund, which was arguably the first of the current small group of venture funds focused on supporting companies that commercialize implementations of aging research, depending on how we want to classify the incubator activities of the Methuselah Foundation over the past decade. Show More Summary

Are Narcissists Able to Tell the Truth About Themselves?

Because people high in narcissism seem so focused on their impressions, you'd think they lie in psychological testing. New research shows when narcissists are most likely to lie.

Delivering RNA to Make Heart Cells Divide More Readily

yesterdayHealth / Aging : Fight Aging

Heart regeneration has been something of a theme this past week. Here, researchers report on a method of spurring greater cell division in the cardiomyocyte population of the heart, cells that usually divide very little. Greater division...Show More Summary

A New Book on the History of Longevity Advocacy, a Backdrop to the Present

yesterdayHealth / Aging : Fight Aging

Ilia Stambler has published a new book on advocacy for longevity science. If you liked his last book, which is freely available online, and covered the recent history of longevity science, the past century of aspirations and efforts to address aging as a medical condition, then you should probably take a look at this one. Show More Summary

Clearing Senescent Cells Partially Reverses Osteoporosis in Mice

2 days agoHealth / Aging : Fight Aging

Senescent cells accumulate in tissues with age, a consequence of the normal operation of cellular biochemistry. While these cells can be beneficial in small numbers and for short period of times, such as while playing a role in wound...Show More Summary

Link between cells associated with aging, bone loss

A causal link between senescent cells -- the cells associated with aging and age-related disease -- and bone loss has been found in mice. Targeting these cells led to an increase in bone mass and strength.

Eclipse Day Reveals Some Personal Changes

2 days agoHealth / Aging : Time Goes By

I don't know about everyone else but if, like me, you live within the path of today's eclipse or within easy driving distance, the event has been a local news story to rival President Trump. All right, that's not quite...

Early Steps in the Tissue Engineering of Intervertebral Discs

2 days agoHealth / Aging : Fight Aging

In this paper, researchers report on progress towards the manufacture of intervertebral discs suitable for transplantation. These tissue structures sit between the bones of the spine, the vertebrae. A sizable proportion of the population suffers at least some degree of degenerative disc disease even quite early in later life. Show More Summary

The Processes of Atherosclerosis Damage the Heart in Addition to Blood Vessels

2 days agoHealth / Aging : Fight Aging

The end stage of atherosclerosis involves blood vessels with walls that are distorted and weakened by inflamed fatty deposits, and the vessel itself narrowed. Sooner or later something important ruptures catastrophically, causing death or serious injury. Show More Summary

ELDER MUSIC: The Jealous Kind

3 days agoHealth / Aging : Time Goes By

This Sunday Elder Music column was launched in December of 2008. By May of the following year, one commenter, Peter Tibbles, had added so much knowledge and value to my poor attempts at musical presentations that I asked him to...

Fight Aging! Newsletter, August 21st 2017

3 days agoHealth / Aging : Fight Aging

Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and...Show More Summary

What Your Earliest Food Memories Say About You

Memories of food associated with growing up influence you in ways you never realized. New research shows the role that food memory plays in adapting to adult life.

INTERESTING STUFF – 19 August 2017

4 days agoHealth / Aging : Time Goes By

EDITORIAL NOTE: After my surgery in June, I stopped publishing Interesting Stuff on Saturdays. I couldn't spend as much time playing around online for good items nor did I have the energy to write it. I'm slowly coming back and...

Exercise Restores Failing Autophagy in Damaged Heart Tissue

5 days agoHealth / Aging : Fight Aging

Despite the very promising progress in aging research that has taken place since the turn of the century, it remains the case that exercise and calorie restriction are still the most reliable and and beneficial methods of improving long-term health and life expectancy. Show More Summary

A Successful Trial of Gene Therapy to Spur Vascular Growth in Heart Disease

5 days agoHealth / Aging : Fight Aging

One approach to the structural damage that takes place in heart disease is to attempt to spur growth of new blood vessels, to deliver nutrients to heart tissue that is currently poorly supplied. Gene therapy is in principle well suited to this goal, as a range of genes are known to be involved in regulating the processes of blood vessel generation. Show More Summary

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