It’s becoming socially more acceptable to admit to finding a mate online, but there remain many misconceptions about online dating. Find out your online dating IQ with this 8-item quiz that separates myth from reality.
Targeting myostatin and related biochemistry is well demonstrated to increase muscle mass and strength in mammals such as laboratory mice. There are even rare natural mutants, including a few cows and humans, who lack normal myostatin and are as a result exceptionally strong in comparison to their peers. Show More Summary
[PERSONAL NOTE: I've not been feeling well for a couple of days – a bad cold or mild flu (this year's vaccine missed a strain or two) – so when I take a few minutes off from napping, I'm writing...
The systematic loss of muscle mass and strength with age is given the name sarcopenia. One of the potential contributing causes involves progressive dysfunction in processing of the amino acid leucine, and this might in theory be partially offset by leucine supplementation in the diet. Show More Summary
The lesson to take away from the last fifteen years of study of the genetics of longevity is that genetic variation in humans is simply not all that important throughout most of life. Aging is caused by damage, and certainly during the...Show More Summary
Using the recent development of killifish as a model organism as a starting point, this popular science article looks at some of the more recent high profile developments in the study of aging. It largely takes the longevity dividend party line of talking about extending healthy life span without extending overall life span, however. Show More Summary
A number of lines of research suggest that the benefits of calorie restriction for health and longevity largely derive from increased cellular housekeeping processes such as autophagy. For example, the calorie restriction response requires neuropeptide Y (NPY), and here researchers explore the linkage of NPY with autophagy. Show More Summary
Or, for that matter, any other kind of information? There are some general rules of thumb that anyone with even minimal critical thinking skills probably uses: • Who is doing the writing? What are his/her credentials? (If there is n...
One of the things that turns up in large sets of data on weight and mortality - by which I really mean amount of fat tissue and mortality - is that both maintaining excess fat tissue and later the loss of that fat tissue are associated with increased mortality. Show More Summary
It is known that greater educational achievement is associated with greater longevity, and this is one facet of a web of related correlations between various measures of intelligence, wealth, and health. To my eyes this probably allShow More Summary
Here is an interesting post from the Buck Institute on sources of funding for fundamental research into aging, with tables listing the various contributing organizations. While looking through the list, it is worth bearing in mind that for really early stage, high risk, novel research the largest sources are unavailable. Show More Summary
Whenever there is an auto accident involving an elder driver, there are hysterical calls to snatch licenses from people when they turn 65. What makes me laugh (ruefully) is that U.S. elected officials are eager to raise retirement age for...
Google is pouring a large amount of money into aging research via the Calico Labs initiative. Their declared aim is to produce treatments that impact the whole of age-related degeneration, and their open support of that goal is certainly...Show More Summary
When it comes to improving your memory, you may have to revise everything you thought can help. New research shows that to remember more, you might have to try remembering less.
Yesterday's post, Part 2 of this series, was supposed to be the end of it. But two pertinent things happened that make it worth extending for a day – especially because I think the topic of elder dating deserves a...
A number of the efforts undertaken by the ever industrious Alex Zhavoronkov of InSilico Medicine involve reaching out into new communities to educate and raise awareness on the need for longevity science and the prospects for developing the means to treat aging. Show More Summary
The struggle to show meaningful progress in treatment of Alzheimer's disease via clearance of amyloid has fueled significant investment into alternative hypotheses regarding the disease process. The biochemistry of Alzheimer's - andShow More Summary
DNA methylation is an epigenetic alteration in which genes are decorated with methyl groups. It is one of a range of epigenetic processes that establish a feedback loop linking the pace at which specific proteins are built from genetic...Show More Summary
Autophagy is one of the cellular housekeeping processes responsible for promptly clearing out damaged proteins and cell components before they cause more harm. Autophagic activity declines with age, in part due to a build up of resilient metabolic waste in lysosomes, the organelles responsible for breaking down materials and structures for recycling. Show More Summary
It is uncontroversial that the age-related deterioration of the vascular system leads to damage to the brain, causing cognitive decline and then dementia. Progressive stiffening due to cross-links and calcification and inflammation-driven...Show More Summary