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Criticizing Programmed Theories of Aging

13 hours agoHealth / Aging : Fight Aging

Today I'll point out an open access critique of programmed aging theories by the originator of the disposable soma theory of aging, one of the modern views of aging as accumulated damage rather than programming. The question of how and why we age is wrapped in a lot of competing theory, but of great practical importance. Show More Summary

Ghrelin Receptor and Inflammaging

yesterdayHealth / Aging : Fight Aging

Ghrelin is related to the hunger response, but has a very broad range of influences on many tissues and systems, including immune system activities. Inflammaging is the name given to the inflammation-focused view of the characteristic decline and dysfunction of the immune system with aging. Show More Summary

Ronni Bennett's and John Oliver's Vacation

The two people in that headline, John Oliver and me, don't really have anything to do with each other except that I think he is a national treasure, and we are both taking some time off. Last Sunday's episode of...

Shorter Period of Rapamycin Treatment in Mice Produces Greater Slowing of Aging

yesterdayHealth / Aging : Fight Aging

Rapamycin, an immunosuppressant and MTOR inhibitor, is known to slow aging in mice - though it has been debated whether this extension of life span is actually a slowing of aging versus a lower rate of cancer. Researchers here try aShow More Summary

An Interview with Kelsey Moody of Ichor Therapeutics, Bringing a SENS Therapy for Macular Degeneration to the Clinic

yesterdayHealth / Aging : Fight Aging

As I mentioned last week, earlier this year Fight Aging! invested a modest amount in the Ichor Therapeutics initiative to develop a treatment for macular degeneration, joining a number of other amateur and professional investors in helping to get this venture started. Show More Summary

3 Ways to Be More Authentic in Your Intimate Relationships

Feeling that you can be authentic in your relationships is certainly one of the keys to fulfillment. New research gives you the tools to test how well you measure up.

Cells can Transfer Lysosomes, Spreading Damaging Age-Related Waste Materials

2 days agoHealth / Aging : Fight Aging

It is known that cells can transfer mitochondria from one to another under some circumstances, and here researchers demonstrate that they can transfer lysosomes as well. The lysosomes in a cell play the role of recycling units, breaking down damaged structures and waste proteins. Show More Summary

Enhancing Cell Therapy to Enable Greater Recovery Following Stroke

2 days agoHealth / Aging : Fight Aging

Researchers here demonstrate a method of improving the effectiveness of a stem cell therapy targeted to brain tissues, enabling the treatment to repair more of the damage caused by a stroke: A team of researchers has developed a therapeutic technique that dramatically increases the production of nerve cells in mice with stroke-induced brain damage. Show More Summary

Mapping the Role of Foxn1 in Thymic Function

2 days agoHealth / Aging : Fight Aging

Researchers have of late been mapping the activities and relationships of Forkhead box protein N1 (Foxn1) in the thymus, and the paper I'll point out today outlines some of the most recent findings. Sadly it isn't open access, but I'm sure that won't stop the determined reader in this day and age. Show More Summary

Good and Bad “Entitlement” News From Congress and Trump World

3 days agoHealth / Aging : Time Goes By

Good News on Medicare Observation Status Many readers have emailed about this issue - one that is boring to read about but crucial to understand. First, a short background: Medicare Observation Status has been a frightful bugaboo for beneficiaries for...

Development of a Cell Therapy to Increase Remyelination in the Brain

3 days agoHealth / Aging : Fight Aging

In this open access paper, results are presented for an animal study of an approach to increasing the pace of remyelination in the brain. Myelin acts as sheathing for the axons that connect nerve cells; when it is degraded, insufficiently maintained, or damaged, the result is dysfunction in the nervous system. Show More Summary

Towards a Regenerative Therapy for the Lacrimal Gland and Dry Eyes

3 days agoHealth / Aging : Fight Aging

The lacrimal gland provides moisture for the eyes, and like all parts of our physiology is prone to decline and failure in old age. Dry eye conditions, some of which are painful and debilitating, are common in old people. Researchers...Show More Summary

Fight Aging! Newsletter, August 22nd 2016

3 days agoHealth / Aging : Fight Aging

Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and...Show More Summary

When You've Been Bad, Is it Enough to Say You're Sorry?

Regret may seem like a watered down version of an apology but, according to new research, honest feelings of regret will have more lasting effects on behavior.

INTERESTING STUFF – 20 August 2016

5 days agoHealth / Aging : Time Goes By

THEY'RE KIDDING, RIGHT? Think about this as you watch: Someone, probably stoned out of his mind one evening, thought this up. But instead of having a laugh the next morning over the silliness of weed-induced ideas, he ran with it...

The Geroscience Network: Determined to Slow Aging through Medical Science

5 days agoHealth / Aging : Fight Aging

Across the last twenty years or so two very important, slow-moving battles over ideas and strategy have been fought within and around the aging research community. The first was to gain acknowledgement that the treatment of aging as a medical condition is a viable goal, and thus obtain the necessary support to make progress towards that goal. Show More Summary

6 Ways to Make a Bad First Impression

First impressions can become last impressions if you’re not careful. These 6 common mistakes can prevent people from getting to know who you really are.

When the Narcissist's Bubble Bursts

Whether you intend to or not, it’s very easy to get swept into the narcissistic bubble where you feel unusually special and entitled. When that bubble bursts, how will you survive?

Investigating the Role of Hsp70 in Clearing out Damaged Proteins

5 days agoHealth / Aging : Fight Aging

Heat shock proteins such as the Hsp70 family are involved in the housekeeping processes that keep cells functioning well by destroying damaged proteins. They become active in response to stresses that cause a higher rate of damage to the protein machinery within cells, such as toxicity or heat - and hence the name. Show More Summary

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