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The One Best Way to Conquer Your Anxiety is to Prevent It

Fear is becoming an increasing reality of daily life, but you don’t have to be overwhelmed by this highly negative emotion. New research shows how to prevent it in the first place.

INTERESTING STUFF – 30 August 2016

3 hours agoHealth / Aging : Time Goes By

NOTE FROM THE EDITOR: Today's Interesting Stuff is longer than usual and there are no animals this week. But there are several campaign-related videos and a whole lot related to old age. There was a large amount of good stuff...

A Review of Telomerase as a Therapeutic Target

15 hours agoHealth / Aging : Fight Aging

Telomerase provides the primary mechanism by which cells lengthen their telomeres. In our species only stem cells and cancer cells do this, while in mice more types of cell use more telomerase. Telomere length determines the limit to cell divisions, a little of the length being lost each time a cell divides. Show More Summary

Building a Tau Immunotherapy that does not Increase Inflammation

yesterdayHealth / Aging : Fight Aging

Alzheimer's disease is associated with the aggregation of misfolded amyloid-? and tau proteins. The consensus position is that these aggregates are the primary cause of pathology, though the biochemistry involved is exceedingly complex and still being mapped. Show More Summary

How Extracellular Matrix Scaffolds Influence Cell Behavior in Therapies

yesterdayHealth / Aging : Fight Aging

One approach to regenerative medicine is to use donor extracellular matrix as a scaffolding material. The extracellular matrix is the support structure created by cells that determines the structural properties of a tissue. Its presence...Show More Summary

A Meditation on Making New Friends While Old

Judging by the number of online stories about loneliness and feeling alone many, many people are longing for a close friend. A best friend. Most of all, someone to trust. These articles are usually written by people much younger tha...

The Effects of Retirement are Complex

yesterdayHealth / Aging : Fight Aging

Whenever looking at correlations between behavior and lifespan, or behavior and health, one should always ask whether calorie intake or physical activity level could be involved. Both animal and human studies tell us that the effects...Show More Summary

A Smad7 Gene Therapy to Inhibit Age-Related Muscle Loss is in Development

2 days agoHealth / Aging : Fight Aging

There are always many ways to influence any specific process in cells and tissues. When it comes to enhanced muscle growth, the most popular approaches so far are myostatin inhibition, such as via gene knockout or the use of antibodies, or increased levels of the myostatin inhibitor follistatin. Show More Summary

GPR17 as a Target to Reduce Measures of Aging in the Brain

2 days agoHealth / Aging : Fight Aging

Researchers here note that leukotriene receptor antagonists appear to reduce inflammation and increase plasticity in the brains of rats. They pin down the receptor GPR17 as a protein of interest in this effect. While not directly addressing...Show More Summary

Exercise and TERRA in Telomere Biology

2 days agoHealth / Aging : Fight Aging

Occasionally I'll post research that is only tenuously relevant to aging, but nonetheless fascinating. That is the case for this article and open access paper on a fairly new and still poorly understood area of telomere biology. TheShow More Summary

The Surprising Psychology of the Email Hack

All too often we hear of a public figure whose email was hacked. What they thought was private becomes grist for the media mill. How would you feel if someone targeted you?

More Details on SENS Research Foundation's ALT Cancer Program

3 days agoHealth / Aging : Fight Aging

The SENS Research Foundation is currently raising funds for the next step in its cancer research program: building one of the necessary foundations for a universal cancer therapy, one form of treatment that can in principle halt all types of cancer. Show More Summary

Weeping with Joy at Clinton's Nomination

3 days agoHealth / Aging : Time Goes By

I sure did surprise myself when that happened yesterday evening. I had written something else for today but then I turned on television, the Democratic convention, and burst into tears – tears of joy - when Secretary...

Stem Cell Therapy as a Potential Glaucoma Treatment

3 days agoHealth / Aging : Fight Aging

Researchers here provide evidence in mice to suggest that stem cell treatments could be used to address some forms of glaucoma, usually caused by an increase in pressure in the eye that can damage the optic nerve and other structures. Show More Summary

Your Identity and Its Surprising Role in Your Email

All too often we hear of a public figure whose email was hacked. What they thought was private becomes grist for the media mill. How would you feel if someone targeted you?

A Few of the More Interesting of Recent Alzheimer's Research Results

3 days agoHealth / Aging : Fight Aging

A large fraction of the public funding devoted to aging research goes towards Alzheimer's disease, a very broad set of initiatives that dovetail with other large investments in mapping and understanding the biochemistry of the brain....Show More Summary

Your Identity and Its Surprising Role in Email

All too often we hear of a public figure whose email was hacked. What they thought was private becomes grist for the media mill. How would you feel if someone targeted you?

What Would You Do if Your Email Got Hacked?

All too often we hear of a public figure whose email was hacked. What they thought was private becomes grist for the media mill. How would you feel if someone targeted you?

Progress in the Use of Bioscaffolds for Muscle Regeneration

4 days agoHealth / Aging : Fight Aging

Researchers have demonstrated some restoration of strength in patients with severe muscle injuries, using scaffold materials derived from the extracellular matrix (ECM) of pig tissues. This is an incremental step forward towards theShow More Summary

Nanog May Improve Function of Old Stem Cells

4 days agoHealth / Aging : Fight Aging

In this research, the scientists involved investigate a potential role for the gene nanog in the aging of stem cells, a prospect that has been studied for a few years now. Nanog is involved in pluripotency, the ability of embryonic stem cells to generate any cell type, but, as is the case for most cellular biology, not in a straightforward way. Show More Summary

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