Today I'll point out a very long post that argues we should pay more attention to the mechanisms of Hutchinson-Gilford progeria syndrome (HGPS, or simply progeria) in normal aging. Progeria is one of a small number of rare conditions in which patients have the appearance of accelerated aging. Show More Summary
Immunotherapy is a broad category, and covers many very different strategies for tackling cancer and other conditions by engineering immune cells or adjusting the behavior of the immune system as a whole. In this case, researchers have...Show More Summary
In this popular science article on the relationship between aging and age-related disease, a researcher discusses one of a number of approaches to producing a biomarker of aging, a sensitive measure of the degree to which an individual is impacted by the cell and tissue damage of aging. Show More Summary
That is the title of a new book by German philosopher Wilhelm Schmid. I quoted from it last June when I wrote about the value of habit; Schmid includes an entire chapter on that. I was reading an advance copy...
The folk at 21st Century Medicine have been working, largely unheralded, for years with the aim of improving the technologies used in cryopreservation of tissue. The goals are twofold: firstly to make cryonics a much more reliable and...Show More Summary
People whose narcissism leads them to believe in the myth of their own invincibility may be setting themselves up for a pretty hard fall.
Comparative biology is an important tool in aging research, as the analysis of similar species with widely divergent life spans can in theory point out the more important mechanisms of aging. The more similar the species the better,Show More Summary
Bone is constantly remodeled at the small scale, created by cells called osteoblasts and destroyed by cells called osteoclasts. One of the proximate causes of osteoporosis, age-related loss of bone mass and strength, is a growing imbalance between these two cell populations. Show More Summary
Is the present human life span enough? This was the topic for a recent debate, wherein Aubrey de Grey of the SENS Research Foundation and Brian Kennedy of the Buck Institute were matched against Ian Ground of Newcastle University and Paul Root Wolpe of the Emory Center for Ethics. Show More Summary
An interesting mechanism that appears to contribute to age-related hair loss was recently identified. It is unusual in that cells of one tissue structure are changing to cells of another as a result of age-related damage: ScientistsShow More Summary
Stem cell transplants spur greater regeneration in an injured heart that would normally be the case, and so far it appears to be the case that this is a matter of signaling that changes the behavior of native cells rather than the transplanted stem cells integrating with native tissue and generating new cells. Show More Summary
As stated clearly in a new, 2016 report from the Economic Policy Insitute (EPI), Social Security is a pillar of the American economy. It is the most effective anti-poverty program in the United States. For more than half of the...
This Sunday Elder Music column was launched in December of 2008. By May of the following year, one commenter, Peter Tibbles, had added so much knowledge and value to my poor attempts at musical presentations that I asked him to...
Your partner may have every intention of being faithful but, without any warning, someone else comes along and turns it all upside down. What will you do?
THE ULTIMATE CAT LADY Except when I was married for awhile half a century ago and we had four cats, I have always had one cat at a time. There is a reason for that: I'm pretty sure if I...
The more out of shape you are, the more pointless you may think it is to exercise. Research shows that anyone can exercise, and reap the benefits, regardless of age or fitness.
After the laboratory, the next stage of development in rejuvenation therapies involves the founding of biotechnology startups. There is no clear-cut point at which research stops being non-profit in the laboratory and starts being for-profit in a venture-funded startup. Show More Summary
As I've told you ad nauseum here, I started studying ageing 20-odd years ago because the received wisdom everywhere in those days was that getting old is awful, the worst thing that could happen to anyone. It consists, they all...
UPDATE 8AM PST Certainly this has gone viral already but I can't resist posting it. While the east coast snow storm is still in full surge, Tian Tian, a panda at the National Zoo in Washington, D.C., appears to be...
Researchers here find an association in an older study population between the presence of cytomegalovirus (CMV) - and other common herpesviruses - and the observed degree of cognitive decline. A good deal of evidence from past yearsShow More Summary