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Recent Papers on Energy Metabolism and Longevity

11 hours agoHealth / Aging : Fight Aging

Here I'll point out a couple of papers on the topic of energy, metabolism, and natural variations in longevity. One of the many ways of looking at the operation of metabolism is from the point of view of energy consumption and expenditure:...Show More Summary

Stem Cells Age as Well

23 hours agoHealth / Aging : Fight Aging

Today I thought I'd point out an interesting post from the Buck Institute team on the topic of stem cell aging. The good news here is that the characteristic age-related decline of stem cell function is an issue that the research community has to engage with on the way to developing effective treatments based on their work. Show More Summary

So: At What Age Do You Want to Become Diseased and Die?

yesterdayHealth / Aging : Fight Aging

Here are a few thoughts on the need for advocacy in longevity science from Rejuvenaction: People don't think that ageing is a disease because they're used to thinking that it's just a stage of life. They will start to finally acceptShow More Summary

A Rare Replication of a Human Longevity-Associated Gene Variant in Different Study Populations

yesterdayHealth / Aging : Fight Aging

It isn't often at all that researchers find an association between longevity and genetic variants in humans that holds up in different study populations. This is quite the contrast with shorter-lived species such as mice, where significant effects on longevity via genetic variants are near commonplace. Show More Summary

Cellular Senescence and Parkinson's Disease

yesterdayHealth / Aging : Fight Aging

The Buck Institute here provides a popular science look at links between cellular senescence and the development of Parkinson's disease. The proximate cause of the symptoms of Parkinson's is the diminishing numbers and function of a small collection of dopamine generating neurons in the brain. Show More Summary

The Latest Glenn Foundation Funding for Aging Research

yesterdayHealth / Aging : Fight Aging

In past years the Glenn Foundation for Medical Research has reinforced the mainstream of the aging research community with grants of a few million dollars apiece to establish or expand laboratories in many major universities and research centers. Show More Summary

60 is Not the New 40

Nor 70 the new 50 but people are still trying to sell that to us. If you pay too much attention to media chatter, you can easily be convinced that old age is a nice, smooth continuation of midlife. If...

Naked Mole Rats Retain Neural Plasticity Across a Life Span

2 days agoHealth / Aging : Fight Aging

Two of the many topics of interest found in the study of longevity are (a) the long-lived naked mole rat and (b) the processes by which the mammalian brain generates new neurons and connections to maintain itself. Today I'll point out...Show More Summary

The Compassionate Way to End a Relationship

Ending a relationship involves pain for both partners, regardless of who initiates the breakup. Although the well-known song proclaims there are 50 ways to leave your lover, the literature identifies 47. People high in compassionate love will be the most likely to use the least painful of these breakup strategies.

Population Life Expectancy Inversely Correlated with Childhood Autoimmune Disease Incidence

2 days agoHealth / Aging : Fight Aging

A researcher here runs the numbers to demonstrate an inverse correlation between autoimmune disease incidence and life expectancy. It is interesting to speculate on the mechanisms here, which are probably not going to turn out to beShow More Summary

The Prospects for Stem Cells to Treat Chronic Wounds

2 days agoHealth / Aging : Fight Aging

Based on the evidence to date, stem cell transplants could be used to treat chronic, non-healing wounds that occur in older patients, though work to be accomplished in order to achieve this goal. Here is an open access review paper on...Show More Summary

Investigations of the INDY Gene Illustrate that "Very Slow" is the Default Speed of Aging Research

3 days agoHealth / Aging : Fight Aging

Here I point out a recent review on the topic of INDY gene manipulations and consequent increased longevity via altered metabolic processes. Given just how long ago this gene was discovered, and how similar at a high level the research...Show More Summary

An Early Attempt to Work Around Immunosenescence

3 days agoHealth / Aging : Fight Aging

Researchers have recently demonstrated a partial restoration of immune response in aged mice using a combination of existing Toll-like receptor agonists. This might be seen as a first step on the road to ways to reverse those aspects of immune system failure with age that depend more on misconfiguration rather than cellular damage. Show More Summary

Does Hollywood Ageism Have Anything To Do with You and Me?

3 days agoHealth / Aging : Time Goes By

In recent weeks there has been a minor flurry of media information – tidbits, mostly – about age and work in relation to female movie stars. I had been sitting on a quotation from actor Maggie Gyllenhaal, wondering what I...

Are Mitochondrial Mutations Really All That Important?

4 days agoHealth / Aging : Fight Aging

Prompted by attention given to a recent study claiming to cast doubt on the primary role of damaged mitochondria in aging, here is a lengthy and detailed article from the SENS Research Foundation on what is known of mitochondrial DNA damage and aging. Show More Summary

9 Ways to Handle Nosy People

Some questions are just too personal, but you’re worried that if you don’t answer them, you’ll seem rude. These 9 tips will give you a graceful way to duck the question and help you protect you from future, similar, assaults on your privacy. You'll also gain important insight into yourself and your sensitivities in the process.

Who Do You Fear, and Why?

Being afraid of another person, except in very rare cases, doesn’t really make sense. It’s time to sort out how much of your fear of others is based in reality and how much is based on your own preconceived notions. Overcoming those fears will help you improve both your relationships and your well-being.

Who Are You Afraid of, and Why?

Being afraid of another person, except in very rare cases, doesn’t really make sense. It’s time to sort out how much of your fear of others is based in reality and how much is based on your own preconceived notions. Overcoming those fears will help you improve both your relationships and your well-being.

INTERESTING STUFF – 27 June 2015

5 days agoHealth / Aging : Time Goes By

ELDERS BENEFIT FROM SUPREME COURT DECISION TOO It was an important win for the American people on Thursday when, in a 6-3 decision, the Supreme Court upheld Obamacare subsidies. A lost could have meant the destruction of the entire law....

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