Today I'll point out an open access critique of programmed aging theories by the originator of the disposable soma theory of aging, one of the modern views of aging as accumulated damage rather than programming. The question of how and why we age is wrapped in a lot of competing theory, but of great practical importance. Show More Summary
Ghrelin is related to the hunger response, but has a very broad range of influences on many tissues and systems, including immune system activities. Inflammaging is the name given to the inflammation-focused view of the characteristic decline and dysfunction of the immune system with aging. Show More Summary
The two people in that headline, John Oliver and me, don't really have anything to do with each other except that I think he is a national treasure, and we are both taking some time off. Last Sunday's episode of...
Rapamycin, an immunosuppressant and MTOR inhibitor, is known to slow aging in mice - though it has been debated whether this extension of life span is actually a slowing of aging versus a lower rate of cancer. Researchers here try aShow More Summary
As I mentioned last week, earlier this year Fight Aging! invested a modest amount in the Ichor Therapeutics initiative to develop a treatment for macular degeneration, joining a number of other amateur and professional investors in helping to get this venture started. Show More Summary
Feeling that you can be authentic in your relationships is certainly one of the keys to fulfillment. New research gives you the tools to test how well you measure up.
It is known that cells can transfer mitochondria from one to another under some circumstances, and here researchers demonstrate that they can transfer lysosomes as well. The lysosomes in a cell play the role of recycling units, breaking down damaged structures and waste proteins. Show More Summary
Researchers here demonstrate a method of improving the effectiveness of a stem cell therapy targeted to brain tissues, enabling the treatment to repair more of the damage caused by a stroke: A team of researchers has developed a therapeutic technique that dramatically increases the production of nerve cells in mice with stroke-induced brain damage. Show More Summary
Researchers have of late been mapping the activities and relationships of Forkhead box protein N1 (Foxn1) in the thymus, and the paper I'll point out today outlines some of the most recent findings. Sadly it isn't open access, but I'm sure that won't stop the determined reader in this day and age. Show More Summary
Good News on Medicare Observation Status Many readers have emailed about this issue - one that is boring to read about but crucial to understand. First, a short background: Medicare Observation Status has been a frightful bugaboo for beneficiaries for...
In this open access paper, results are presented for an animal study of an approach to increasing the pace of remyelination in the brain. Myelin acts as sheathing for the axons that connect nerve cells; when it is degraded, insufficiently maintained, or damaged, the result is dysfunction in the nervous system. Show More Summary
The lacrimal gland provides moisture for the eyes, and like all parts of our physiology is prone to decline and failure in old age. Dry eye conditions, some of which are painful and debilitating, are common in old people. Researchers...Show More Summary
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and...Show More Summary
This Sunday Elder Music column was launched in December of 2008. By May of the following year, one commenter, Peter Tibbles, had added so much knowledge and value to my poor attempts at musical presentations that I asked him to...
Regret may seem like a watered down version of an apology but, according to new research, honest feelings of regret will have more lasting effects on behavior.
THEY'RE KIDDING, RIGHT? Think about this as you watch: Someone, probably stoned out of his mind one evening, thought this up. But instead of having a laugh the next morning over the silliness of weed-induced ideas, he ran with it...
Across the last twenty years or so two very important, slow-moving battles over ideas and strategy have been fought within and around the aging research community. The first was to gain acknowledgement that the treatment of aging as a medical condition is a viable goal, and thus obtain the necessary support to make progress towards that goal. Show More Summary
First impressions can become last impressions if you’re not careful. These 6 common mistakes can prevent people from getting to know who you really are.
Whether you intend to or not, it’s very easy to get swept into the narcissistic bubble where you feel unusually special and entitled. When that bubble bursts, how will you survive?
Heat shock proteins such as the Hsp70 family are involved in the housekeeping processes that keep cells functioning well by destroying damaged proteins. They become active in response to stresses that cause a higher rate of damage to the protein machinery within cells, such as toxicity or heat - and hence the name. Show More Summary