The path of the life sciences is to learn all there is to know about human biochemistry, regardless of use or application. The path of medicine, like the path of engineering, is to take what is known today and build the best and most useful technologies possible in that environment of incomplete knowledge. Show More Summary
File this post under Ronni was too weary and/or lazy to write on Wednesday. It happens to all of us, you know. I own an elegant, little easel frame. It is quite small – about two-and-a-half by three inches or...
There is a large body of evidence to link cognitive decline in aging with corresponding decline in blood vessel integrity. A variety of processes in aging contribute to failing elasticity and structural remodeling of blood vessel walls,...Show More Summary
Efforts to treat Alzheimer's disease by clearing the amyloid beta (A?) deposits and related precursors associated with the progression of the condition have proven to be challenging, beset with failures and complications. Wherever there...Show More Summary
A point I frequently make is that while there exists a wide range of potential approaches to the development of therapies to treat aging, it is important to divide these approaches into two buckets. Firstly there are potential therapies...Show More Summary
The general consensus among researchers is that over the last few centuries of increasing human life expectancy most of the early gains were due to reductions in mortality in youth, such as those caused by infectious disease, malnutrition, and the like. Show More Summary
It has become a tenet of old age that without plenty of friends and family, and an active social life, we are doomed to die before our time. In fact, one study, as reported in The Guardian last year, went...
Klotho is one of a range of longevity-associated genes identified in animal studies. You might recall that last year researchers identified a klotho variant associated with better cognitive function in humans. It didn't appear to protect against age-related decline as the researchers hoped, however. Show More Summary
It would be an interesting and possibly rather depressing exercise to compare funding for reversal of age-related hair loss to that for the effective treatment of various other aspects of aging. Hair restoration, I think, is fairly well funded in comparison with many lines of research that I consider to be far more important. Show More Summary
Whether in your relationships or your work life, it’s inevitable that you’ll be involved in a conflict with someone over something. These 17 principles will guide you in learning how best to put your emotions, motives, and communication skills to settle any of those conflicts in to produce successful results.
In 1999, four middle-ish-aged guys who were stars in the development of the still-emergent internet wrote a book about how the internet, an amazing global “conversation” platform whereby individuals could share information at blinding speeds that gave them, us –...
Immunotherapy is a promising approach for the treatment of Alzheimer's disease, in which immune cells are directed to attack amyloid aggregates or precursor proteins associated with the condition. More pertinently, this field of research...Show More Summary
More than six years ago a research group demonstrated that autophagy can be boosted in the liver to reverse some of the age-related decline in function of that organ. Old mice were shown to have some measures of liver function little different from young mice. Show More Summary
Would it be a demographic catastrophe if people were able to live significantly longer, or even became immortal?
Contrary to Santayana, some who cannot remember the past are doomed not to repeat it.The public option may be on life support, but we have already tried it, and it's a huge success.
Is tweeting for bird brains? Since when did the fashionistas declare exhibitionism to be the new black?
Obama's mistake was not going with the devil we know.
We have the best healthcare money can buy, if you can afford to buy it.