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6 Ways to Turn the Worst Part of Your Day into the Best

Getting to places on time, whether work or social occasions, can be a hassle. New research based on travel habits of commuters shows how to be less stressed and more punctual.

RIPK1 as a Target to Reduce Microglial Dysfunction in Alzheimer's Disease

4 days agoHealth / Aging : Fight Aging

One component of most neurodegenerative diseases is that classes of immune cells resident in the brain adopt disruptive, inflammatory behaviors. This is a reaction in some way to growing levels of damage in the form of aggregated proteins, such as amyloid-? and tau in Alzheimer's disease, but it isn't a helpful reaction. Show More Summary

A Question of Organ Recitals

4 days agoHealth / Aging : Time Goes By

A few days ago in a comment, a reader made an approving reference to a friend who refused to take part in groups of old people who indulge in “organ recitals” - that supposedly clever but disparaging phrase for discussion...

Encapsulated Stem Cells Improve Heart Regeneration

4 days agoHealth / Aging : Fight Aging

Researchers here report on a cheaper implementation of encapsulation for transplanted stem cells, preventing the recipient's immune system from attacking cells originating from a different individual or even different species. SinceShow More Summary

6 Best Ways to Beat Procrastination and Get There on Time

Getting to places on time, whether work or social occasions, can be a hassle. New research based on travel habits of commuters shows how to be less stressed and more punctual.

6 Best Ways to Stop Procrastinating and Get There on Time

Getting to places on time, whether work or social occasions, can be a hassle. New research based on travel habits of commuters shows how to be less stressed and more punctual.

An Introduction to DAF-16 and FOXO in the Context of Aging and Longevity

5 days agoHealth / Aging : Fight Aging

In the early 1990s Cynthia Kenyon and others produced the first C. elegans nematode worms to exhibit significantly extended longevity through a single gene mutation, in daf-2, the nematode version of the insulin-like growth factor 1 (IGF-1) receptor, and went on to map the relevant nearby biochemical landscape of these mutants. Show More Summary

6 Ways to Get Where You Need to Be On Time

Getting to places on time, whether work or social occasions, can be a hassle. New research based on travel habits of commuters shows how to be less stressed and more punctual.

Aiming to Develop Monoclonal Antibodies for Glucosepane

5 days agoHealth / Aging : Fight Aging

Funded by the SENS Research Foundation and allied philanthropists, the researchers at the Spiegel Lab are working on the tools needed to build the means to remove glucosepane cross-links from aged tissue. Like clearance of senescentShow More Summary

Is Dementia Incidence in Decline?

5 days agoHealth / Aging : Fight Aging

When the population as a whole is aging because of historical changes in birth and mortality rates, meaning that an increasing percentage of people are older rather than younger with each passing year, it is perfectly possible to observe...Show More Summary

HSP90 Inhibitors as Another New Class of Potential Senolytic Drug Compounds

6 days agoHealth / Aging : Fight Aging

The increasing number of senescent cells present in older tissues is one of the root causes of degenerative aging. It is also the closest to being effectively reversed. An open access paper describing the evidence for HSP90 inibitors to selectively destroy senescent cells was published earlier this month. Show More Summary

Reviewing the Effects of Exercise on Mitophagy and Mitochondrial Function

6 days agoHealth / Aging : Fight Aging

Mitochondrial damage is important in aging, and many of the means shown to modestly slow aging in various species involve increased cellular maintenance activities directed towards mitochondria. One of these is mitophagy, a specialized form of autophagy that recycles damaged mitochondria. Show More Summary

What Medigap Changes Mean For Elders

6 days agoHealth / Aging : Time Goes By

[EDITORIAL NOTE: Today's post is a bit wonkier than I usually publish but it is important for U.S. readers who will become eligible for Medicare in the next two years, and for current beneficiaries too. It shouldn't be hard to...

The First Practical Means of Human Rejuvenation are Not Distant

6 days agoHealth / Aging : Fight Aging

The first, narrowly focused rejuvenation therapies based on repair of the cell and tissue damage that causes aging already exist. They are entering trials, they are under development in companies. Senolytic therapies to clear senescent...Show More Summary

Fight Aging! Newsletter, September 18th 2017

last weekHealth / Aging : Fight Aging

Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and...Show More Summary

ELDER MUSIC: 1925

This Sunday Elder Music column was launched in December of 2008. By May of the following year, one commenter, Peter Tibbles, had added so much knowledge and value to my poor attempts at musical presentations that I asked him to...

8 Signs That Someone May Be Living With Social Anxiety

One of the most common forms of anxiety people experience involves an extreme fear of being judged by others. Find out how you can identify and cope with social anxiety’s symptoms.

14 Questions to Ask About the Quality of Your Relationship

Considering the many factors involved in relationships, it might seem impossible to narrow them down to a reasonable number. New research shows which are the 14 common elements.

INTERESTING STUFF – 16 September 2017

PETER TIBBLES' BIRTHDAY Today is the birthday of TimeGoesBy's inimitable Sunday musicologist. I'm not sure which one exactly but it's in the area of early 70s. His musical knowledge is phenominally wide and deep, and he's funny too. Let's start...

Brain halves increase communication to compensate for aging, study finds

Increased communication between distant brain regions helps older adults compensate for the negative aspects of aging, reports a new study.

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