Following the breakup of a close romantic relationship, both partners are likely to experience distress. However, when the breakup is one brought about by the partner, this distress often translates into rebound sex. Who's at risk and who isn't depends on a complex set of 4 relationship factors. read more
THE GREAT ELIZABETH WARREN SPEECH It was Friday evening before the great Congress shutdown vote - 12 December. Massachusetts Senator Elizabeth Warren took to the microphones that evening to speak for we the people against Wall Street overreach – specifically,...
The cryonics industry provides the only alternative to the grave for people who will age to death prior to the advent of rejuvenation treatments. Sadly, even after four decades of service this remains a small industry and only a tiny...Show More Summary
The need to find meaning in your life might not be something you ponder on a daily basis but it lies at the root of your sense of worth. By answering these 5 questions, you can measure your progress toward that ultimate source of happiness. read more
PROGRAMMING REMINDER: Repeating an announcement I made a couple of days ago: Back in 2008, I made a presentation about web design for elders at the Gnomedex Conference in Seattle. I met a lot of young, interesting and engaged tech.....
Not all muscles in the body age equally, it seems, and those surrounding the eye are spared many of the degenerative changes that occur elsewhere. Investigating why this is the case may help to inform other lines of research that aim...Show More Summary
Life spans in short-lived animals can be made to vary far more in response to circumstances than the life spans of longer-lived animals. In the case of calorie restriction there is an evolutionary explanation in that if periods of famine...Show More Summary
Every few years a new hot thing emerges in the field of drug candidates to slow aging. It was sirtuins for a while and then rapamycin and there will be others in due course. This happens because it is very possible to raise funding,Show More Summary
Cells can enter a senescent state in response to damage, ceasing to divide. This reduces the risk of cancer under most circumstances, but is also a part of the wound healing process. This isn't all good, however. Senescent cells secrete...Show More Summary
Every election year, I am puzzled, and troubled too, that “my tribe” - elders – reliably votes in large numbers against its own best interests, electing Republican politicians who, almost to a person, want to cut Social Security and Medicare....
It was Aesop (c. 620-564 BC) in his fable titled The Fox and the Lion who is credited with the aphorism, familiarity breeds contempt. (You can read one version of the fable here. It's short – three sentences.) I have...
Life expectancy at birth is a statistical measure, internally consistent and useful for comparisons across time. Insofar as it has a real meaning it is the average expected life span of a person born now if medical technology going forward exactly repeated past availability and cost over the life spans of people presently at the end of life. Show More Summary
Many types of metabolic waste and byproduct molecules are generated by the normal operation of cellular metabolism. You can't run an engine without exhaust or a factory without waste generation. The majority of these unwanted outputs...Show More Summary
IMPORTANT PROGRAMMING NOTE: Back in 2008, I made a presentation about web design for elders at the Gnomedex Conference in Seattle. I met a lot of young, interesting and engaged tech workers there and one of the them was Dave...
Researchers here find an association between the amount of mitochondrial DNA (mtDNA) in tissues and the risk of frailty and mortality. The less mitochondrial DNA you have, the worse off you are likely to be, or so it seems. It is anShow More Summary
The latest Google Ventures annual report has a third of new investments going to the life sciences and health in the past year. This is of interest principally in the context of Calico Labs and its focus on finding ways to treat aging. Show More Summary
The protein ?-synuclein is involved in Parkinson's disease in much the same way that ?-amyloid is involved in Alzheimer's disease. These particular misfolded proteins accumulate with age to form deposits in everyone's brain tissues, but this is seen to occur to a much greater extent in those suffering from the related neurodegenerative condition. Show More Summary
Change is, as they say, an inevitable fact of life. However, it’s not always so easy to make those changes that you most desire. By adopting the mindset of the "agile innovator,” however, those changes might be easier to tackle than you think. read more
[EDITORIAL NOTE: Usually, on big holidays, I post a photo or video, something short as a celebration and let us otherwise have a day off from the blog. This year, a contributor to The Elder Storytelling Place sent a Hanukkah...
Collections of twins are the closest that researchers can get in humans to an ideal study situation in which a large number of genetically identical individuals follow the same life courses. Comparison studies with as many factors as...Show More Summary