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The Geroprotectors Database: Curated Lifespan Study Data

12 hours agoHealth / Aging : Fight Aging

The Geroprotectors online database was recently announced, a curated reference of lifespan data studies carried out in recent years. It isn't surprising to see João de Magalhães on the list of those involved, given his past focus onShow More Summary

Are You and Your Partner Faking Intimacy?

Being involved in a truly intimate relationship means that you reveal your real self to your partner. The question is whether the self you show to your partner is authentic or sham. Find out whether you and your partner are being as honest as possible with each other.

CD47 as a Cancer Target May Rely on Dendritic Cells Rather than Macrophages

22 hours agoHealth / Aging : Fight Aging

CD47 is a marker for cancer cells in a broad range of cancers, and thus targeting it offers the prospect of a cancer treatment that can be applied to many more patients than is usually the case. A number of research groups are working...Show More Summary

The Mainstream View of Longevity Science: Drug Discovery to Slightly Slow Aging

23 hours agoHealth / Aging : Fight Aging

As the paper linked here illustrates, pharmacology remains the main focus for that part of the research community interested in intervening in the aging process. Those involved understand that this progress is very slow and very expensive...Show More Summary

Is Science on Course to Reverse Ageing?

23 hours agoHealth / Aging : Time Goes By

Ever since humankind climbed down from the trees, people have been looking for a fountain of youth along with its companion aspiration, immortality. Many a myth is based on these yearnings including the Greek legend in which Eos, goddess of...

An Illustrative Consideration of Mitochondrial Haplogroup Differences in Human Longevity

yesterdayHealth / Aging : Fight Aging

In the open access paper quoted here, researchers suggest that variations in the MOTS-c peptide encoded in mitochondrial DNA may have some effect on life expectancy in at least some human populations. The present landscape of statistical...Show More Summary

How to Do the Right Thing (Almost) Every Time

Temptation is a normal part of life, whether in love, business, or food. As much as you want to stay on the straight and narrow, you may be faced with a choice that greatly tests your resolve. Here’s how to make sure that you stick to your own moral compass.

Raised Levels of FKBP1b Restore Calcium Regulation and Improve Cognitive Function in Aging Rats

yesterdayHealth / Aging : Fight Aging

Researchers here argue that failing calcium regulation provides a meaningful contribution to neurodegeneration, and demonstrate improvement in old rats via altered levels of a protein involved in calcium metabolism. As is the case for most research, this identifies only one step of cause and consequence in longer chain of events. Show More Summary

Autoimmunity as a Possible Side-Effect of Cancer Immunity

yesterdayHealth / Aging : Fight Aging

It has long been hypothesized that there is a link between autoimmune conditions and the immune response to cancer, and this article covers some of the high points. Autoimmune conditions are a set of complicated failure modes in a very complex system, in which the immune system attacks the patient's own tissues. Show More Summary

Calorie Restriction: Good for Humans

2 days agoHealth / Aging : Fight Aging

Results from the most recent two year CALERIE trial of human calorie restriction were published earlier this year, but the associated publicity materials have only just now made it to the presses. Calorie restriction, or to be more precise...Show More Summary

Baby Boomers and Social Networking: The Revolutionary Powers for Change with Twitter, Facebook, LinkedIn, and YouTube

2 days agoHealth / Aging : Boomers

The Internet provides Baby Boomers with the most potent medium in history to effect change, nearby and far away. Social networks are no longer merely local and temporal but rather global and eternal. We have daily opportunities to influence hundreds, thousands or even millions with a single Tweet, Facebook post, YouTube, or Linked-In update. Show More Summary

Insight into the Machinations of Classifying Aging as a Disease

2 days agoHealth / Aging : Fight Aging

The open access paper quoted here provides some insight into present attempts to change the regulatory classification of aging in the lab and the clinic: the prospect for meaningful progress in the science is real, but regulation is holding things back, which is why so many articles have appeared of late on whether or not aging is a disease. Show More Summary

Dietary Glycemia Correlates with Visual Health in Aging

2 days agoHealth / Aging : Fight Aging

Researchers here note a correlation between glycemic index, a measure of the impact of carbohydrate content of food on blood glucose, and risk of suffering age-related blindness. Given the comparatively large influence of calorie intake...Show More Summary

“How to Age Gracefully”

2 days agoHealth / Aging : Time Goes By

Last month, a long-running Canadian Broadcasting Corporation (CBC) radio program, Wiretap, came to an end. The show and its host, Jonathan Goldstein, had been charming listeners on the CBC, SiriusXM radio and Public Radio International (PRI) radio for 11 years....

October 1st is International Longevity Day: Events are Planned

3 days agoHealth / Aging : Fight Aging

October 1st is the UN International Day of Older Persons, but our community would like it to also be Longevity Day, a time to remind the world that research into human rejuvenation is practical, that near-future therapies are plausible, and that all of this will move much faster with greater funding and support. Show More Summary

What Happens When a Narcissist's Love Turns Into Rage

No one like being rejected or left, but for narcissistic individuals, a rejection can become the stimulus for a dangerous over-reaction. If you’ve ever been the target of one of these attacks, you know how frightening it can be. Understanding the cause of your ex’s rage can help both of you cope more reasonably.

A Study Shows Older People are Now Smarter but Less Fit

3 days agoHealth / Aging : Fight Aging

Trends in technology and increasing wealth improve health due to greater access to better forms of medicine, but also tend to produce a fatter, less fit older population, a consequence of the broadening range of attractive and affordable transportation devices and calories. Show More Summary

Chimeric Antigen Receptor T-cells versus Solid Tumors

3 days agoHealth / Aging : Fight Aging

The future of cancer research is targeting, meaning the ability to destroy cancer cells efficiently and with few to no side-effects on normal tissues. Chimeric antigen receptor (CAR) T-cells are a step forward in this regard, and have proven to be an effective treatment for leukemia in trials. Show More Summary Officially Launches, Crowdfunding the Development of a Cure For Aging

4 days agoHealth / Aging : Fight Aging

Philanthropy has an important role in funding medical research, and thus crowdfunding will have an equally important role in the years ahead: it is collaborative philanthropic, the diverse will of the public, organized and made real....Show More Summary

Rejuvenation Biotechnology 2015 Wraps Up on a High Note

4 days agoHealth / Aging : Fight Aging

An official release from the SENS Research Foundation on the recent Rejuvenation Biotechnology 2015 conference: The Rejuvenation Biotechnology conference brings together experts from research, academia, industry, policy, finance andShow More Summary

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