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Improving Natural Mitochondrial DNA Repair Mechanisms as a Potential Way to Slow the Progression of Aging

3 hours agoHealth / Aging : Fight Aging

Our cells each contain hundreds of mitochondria, the descendants of symbiotic bacteria that are responsible for generating the chemical energy store molecule adenosine triphosphate (ATP) used to power cellular activity, as well as being deeply integrated with many other important cellular processes. Show More Summary

Are Old People (and Everyone Else) Sleeping All Wrong?

14 hours agoHealth / Aging : Time Goes By

ITEM 1: Everyone knows that insomnia is a common condition of growing old; it just comes with age, like wrinkles. ITEM 2: We also know that the proper and natural way to get a good night's sleep is to bed...

Towards Manufactured Blood

15 hours agoHealth / Aging : Fight Aging

One of the near future goals in the tissue engineering field is the low-cost mass-manufacture of blood, removing the need for donations and blood banks. Development leading towards mass produced blood has proven a slower process than hoped, however. Show More Summary

Investigating the Normal Regulation of Insulin Receptors in Aging

15 hours agoHealth / Aging : Fight Aging

Genetically altered organisms lacking an insulin receptor live longer. The related processes of insulin and growth hormone signaling are one of the better-studied areas of biochemistry in the context of aging as a result, largely focused on loss of function mutants and why they are long-lived. Show More Summary

The California Life Company is Secretive, but Sadly Also Probably Irrelevant

yesterdayHealth / Aging : Fight Aging

It will not be news to this audience that the California Life Company, or Calico for short, Google's venture into aging research, is secretive. Outside of the staff, few people can do more than read the tea leaves regarding what exactly they are up to. Show More Summary

Using CRISPR to Suppress Cytokine Receptors and Reduce Inflammation

yesterdayHealth / Aging : Fight Aging

Researchers believe they have established a method of reducing inflammation via epigenetic alterations that can in principle be broadly applied to a range of conditions in which inflammation is important. Inflammation is significantShow More Summary

Relations Between the Endoplasmic Reticulum and Mitochondria in Aging

yesterdayHealth / Aging : Fight Aging

This open access paper serves as a reminder that there is an enormous amount of complexity yet to be mapped and understood in cellular biochemistry, let alone in the way that this biochemistry changes over the course of aging. For example,...Show More Summary

Further Investigations of Cellular Senescence in Muscle Aging and Frailty

2 days agoHealth / Aging : Fight Aging

As a topic for aging research, cellular senescence passed its tipping point a few years ago. Prior to that growth of interest and attention it was a struggle to raise funding for this area of work, and thus it didn't matter how compelling the evidence was for its involvement in the processes of aging. Show More Summary

A Faster Way to Help Determine Who’s Psychopathic

It certainly is of great value to be able to sniff out a psychopath. There are many possible tests and quizzes; the latest entry promises to be the quickest, and maybe the best.

5 Steps to Get Anyone to Open Up to You

Curiosity about other people is a natural part of the human condition. Using knowledge from new research on persuasion, you can satisfy that curiosity with these 5 steps.

A Nanoparticle Cancer Vaccine Effective Against Multiple Varieties of Cancer

2 days agoHealth / Aging : Fight Aging

The most important projects in cancer research are those that might produce therapies effective against many different types of cancer. There are too many varieties of cancer and individual tumors can evolve too rapidly for the research community to achieve its goals by working on highly specific therapies. Show More Summary

Staying Sane in This Dark Night of the American Soul

2 days agoHealth / Aging : Time Goes By

It is no secret around here that I think John Oliver is the most brilliant of the bumper crop of smart, left-wing comedians we have now who help keep non-Trumpers a bit sane during this dark night of the American...

A Mechanism to Link Air Pollution and Cardiovascular Disease

2 days agoHealth / Aging : Fight Aging

Air pollution is associated with increased mortality and risk of a variety of age-related diseases, but as is often the case in human epidemiological data it isn't all that clear as how much of this is due to direct versus indirect effects. Show More Summary

More Evidence for Senescent Cells as a Significant Cause of Osteoarthritis

3 days agoHealth / Aging : Fight Aging

UNITY Biotechnology has obtained a large amount of venture funding in order to work on senolytic therapies, treatments capable of removing significant numbers of the senescent cells that accumulate with advancing age. Cellular senescence...Show More Summary

Five Ways to Fit in with Just About Any Crowd

There are times for individuality but other times when you want to blend into the crowd. New research on conformity and mental health suggests how to gain acceptance.

An Approach to Deliver Chimeric Antigen Receptor T Cells to Solid Tumors

3 days agoHealth / Aging : Fight Aging

The approaches to cancer therapies that we should pay attention to are those capable of targeting many different types of cancer. The only practical way to meaningfully accelerate progress towards robust control of cancer as a wholeShow More Summary

Exercise Improves Cognitive Function in Older Individuals

3 days agoHealth / Aging : Fight Aging

Researchers here analyze the results from dozens of papers in which exercise was shown to have a beneficial effect on cognitive function in older adults. The broad consensus is that the mechanisms for this effect primarily involve vascular health. Show More Summary

SENS Research Foundation Expands Collaboration with the Buck Institute to Work on Senescent Cells and Immune Aging

4 days agoHealth / Aging : Fight Aging

The SENS Research Foundation and the Buck Institute for Research on Aging are both based in the Bay Area, California, and collaborate on a small variety of projects relevant to the development of rejuvenation therapies. This includes...Show More Summary

Osteoarthritis as an Inflammatory Condition

4 days agoHealth / Aging : Fight Aging

This open access paper discusses current views on the degree to which osteoarthritis is driven by inflammation, as is the case for many other age-related diseases. With aging the immune system declines into a malfunctioning state ofShow More Summary

Evidence for Fat-Triggered Immune Dysfunction in the Liver to Contribute to the Symptoms of Type 2 Diabetes

4 days agoHealth / Aging : Fight Aging

In this research, scientists explore a link between the presence of excess fat and the dysfunctional blood sugar regulation that is characteristic of type 2 diabetes. The vast majority of type 2 diabetes patients suffer the condition...Show More Summary

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