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Life’s Endings and How We Make Sense out of Them

When something important in your life comes to an end, whether your career or your relationship, the process may be more difficult to cope with than you might realize. Ultimately, it’s your identity, and the sense you make of that ending, which will determine how you emerge from life’s transition points.

INTERESTING STUFF – 1 August 2015

11 hours agoHealth / Aging : Time Goes By

1965 MEDICARE SIGNING ON TIMES FRONT PAGE It's always fun to see newspaper front pages from important past events. (Hmmmm. With the internet and cell phones taking over news, will these historical artifacts disappear, I wonder?) Anyway, I missed posting...

DRACO Illustrates the Poor Funding Situation for Radical Departures from the Existing Status Quo

22 hours agoHealth / Aging : Fight Aging

DRACO, double-stranded RNA activated caspase oligomerizer, is a broadly applicable antiviral technology that has been under development at a slow pace for quite some time now. You might recall some publicity back in 2011, for example, but that marked the results of years of earlier work. Show More Summary

The Organoid Stage of the Tissue Engineering Revolution

yesterdayHealth / Aging : Fight Aging

The first stage for commercially useful tissue engineering is testing and further research, and that is actually well underway. Tissue sections for test and research purposes don't have to be large, and therefore the big problem of how to generate suitable blood vessel networks doesn't have to be solved yet. Show More Summary

Slowing Aging By Restricting Cryptic Transcription

yesterdayHealth / Aging : Fight Aging

Researchers have demonstrated slower aging in yeast by increasing H3K36 methylation, which has the effect of restricting certain forms of transcription, the first step in the process of gene expression whereby proteins are generated from their genetic blueprints. Show More Summary

A New Elder Playground in My Town

About two-and-a-half-years ago, I told you about elder playgrounds and that I was heading a small committee of the 50-plus Advisory Board of the City of Lake Oswego, to look into details of building one in Lake Oswego, Oregon. They....

The Struggle to Find Truth from a Position of Ignorance

yesterdayHealth / Aging : Fight Aging

Today I stumbled over a popular press article on the topic of longevity science, in which a fair amount of attention is given to Aubrey de Grey and the SENS Research Foundation vision for rejuvenation biotechnology. Like most such articles...Show More Summary

Targeting an Improvement in Protein Quality Control

2 days agoHealth / Aging : Fight Aging

A range of research efforts aim at finding ways to improve or enhance the activity of cellular maintenance mechanisms involved in ensuring quality control. Proteins are the building blocks of cell machinery but constantly become damaged or misfolded, which can then cause harm through incorrect function. Show More Summary

Supercentenarian Research Study

2 days agoHealth / Aging : Fight Aging

A number of ongoing research programs aim to collect more data on the biochemistry and genetics of the oldest of old people, and here is an example of one of them. I don't believe that these efforts contribute greatly towards building...Show More Summary

5 Ways to Deliver Bad News With a Minimum of Pain

Very few, if any, of us truly enjoys being the bearer of bad news. If you have no choice but to be that messenger, there are ways to get the job done with a minimum of damaged feelings. These 5 strategies will help you figure out how to make the best out of some of life’s unpleasant situations.

An Update on Spurring Heart Regeneration via PIM-1

2 days agoHealth / Aging : Fight Aging

A group of US researchers have demonstrated the potential to induce greater regeneration in heart tissue through overexpression of PIM-1. This is one of many varied approaches to generating greater repair and maintenance of tissues presently...Show More Summary

Towards Better Cryoprotectants, With an Eye on Thawing

3 days agoHealth / Aging : Fight Aging

Below find an interesting discussion of one research program aimed at producing a better class of cryoprotectant that enables tissue thawing without damage. The organ storage and cryonics industries have many of the same technical goals:...Show More Summary

Suggesting the Correlation Between Intelligence and Longevity is Mostly Genetic

3 days agoHealth / Aging : Fight Aging

Researchers building on twin study data are suggesting that the well-known correlation between greater intelligence and a little additional longevity is mostly genetic in nature, not a matter of more intelligent people making betterShow More Summary

Happy 50th Birthday, Medicare

3 days agoHealth / Aging : Time Goes By

Rejoice in our good fortune, my friends. Tomorrow, 30 July 2015, is the 50th anniversary of the day President Lyndon B. Johnson signed the Medicare bill into law. Take a look: Until I was poking around the internet to prepare...

The Wealthy are Just Like the Rest of Us in that Many Want to Do Good in the World

3 days agoHealth / Aging : Fight Aging

The public echo chamber is often crowded by class warfare sentiments, and they are rarely absent from any discussion of progress in medicine. The green-eyed monster of jealousy dons its best suit and those without power denounce those who have more of it because of their greater wealth. Show More Summary

How Do You Handle Your Insecurities?

It’s natural to feel insecure from time to time, but these feelings can get in the way of your happiness. Figuring out where those insecurities come from is the first step to overcoming them.

More Salivary Gland Engineering

4 days agoHealth / Aging : Fight Aging

Here is recent news of another team working to engineer salivary gland tissue, one of many parts of the body typically given little thought until it stops working. This team doesn't seem to be as close to a functional end result as the...Show More Summary

Transthyretin Amyloidosis is More Prevalent than Thought

4 days agoHealth / Aging : Fight Aging

Evidence suggests that transthyretin (TTR) amyloidosis, also known as senile systemic amyloidosis, is the condition that kills the oldest people, those who have survived every other aspect of aging to reach ages of 110 and greater. Here,...Show More Summary

The Failing Immune System and Its Role in Pulmonary Disease

4 days agoHealth / Aging : Fight Aging

In the paper quoted below, researchers review the links between immune system dysfunction in aging and pulmonary diseases - diseases of the lungs, ranging from infections to fibrosis. This is just one of many classes of medical condition that are much more serious and frequent in the elderly. Show More Summary

Altering Metabolism to Slow or Override Aspects of Aging

5 days agoHealth / Aging : Fight Aging

Below find linked a popular science article on some of the strands of research that aim at safely altering the operation of cellular metabolism to either (a) gently slow aging by reducing the pace at which underlying cell and tissue damage accumulates or (b) override some of the reactions to cellular damage that cause declines in tissue maintenance. Show More Summary

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