Axons extend from nerve cells, grouped in bundles to form nerves, with the longest axons running for a meter or more. When severed they tend not to regrow, a limitation that researchers are trying to work around. Here is one of a number...Show More Summary
Targeting antioxidants to the mitochondria inside cells has been shown to produce enough of a benefit to build therapies for a number of conditions, with better outcomes than standard antioxidant treatments. Researchers developing mitochondrially...Show More Summary
That's the first half of a maxim that is crucial to understanding what old age is like and if you've been hanging out at this blog for awhile, you've read it before: If you seen one old person, you've seen...
This Sunday Elder Music column was launched in December of 2008. By May of the following year, one commenter, Peter Tibbles, had added so much knowledge and value to my poor attempts at musical presentations that I asked him to...
We tend to associate whining with the behavior of toddlers, but there are plenty of adults who could equal the whininess of any two-year-old. These 6 tips will help you turn your complaints into effective strategies to get others to gladly give you what you want.
SMART WATCHES FOR OLD PEOPLE There have long been pendants for elders to wear around our necks to make it one-touch easy to call for help in an emergency. Now there are at least two companies making these devices more...
Many researchers investigate inflammation, but like everything involving the immune system it is a very complex collection of processes, yet to be fully understood, and especially in the role it plays in degenerative aging. The greater...Show More Summary
If verified by other laboratories, this seems like a meaningful step forward in understanding the physical structure of memory. A greater knowledge of the biological basis for memory storage has important applications in many fields,...Show More Summary
The number of scientific conferences covering the molecular biology of aging seems to be growing. Here is a recently published report from a conference held last year, for example: Aging is a fundamental problem that the world is currently facing. Show More Summary
American Independence Day is a great, dramatic story. Here are its bare bones. Thomas Jefferson, just 33 years old in the year of 1776, resisted writing the Declaration of Independence. He was John Adams' choice and Adams prevailed. Quoting Adams'...
Here I'll point out a couple of papers on the topic of energy, metabolism, and natural variations in longevity. One of the many ways of looking at the operation of metabolism is from the point of view of energy consumption and expenditure:...Show More Summary
Today I thought I'd point out an interesting post from the Buck Institute team on the topic of stem cell aging. The good news here is that the characteristic age-related decline of stem cell function is an issue that the research community has to engage with on the way to developing effective treatments based on their work. Show More Summary
Here are a few thoughts on the need for advocacy in longevity science from Rejuvenaction: People don't think that ageing is a disease because they're used to thinking that it's just a stage of life. They will start to finally acceptShow More Summary
It isn't often at all that researchers find an association between longevity and genetic variants in humans that holds up in different study populations. This is quite the contrast with shorter-lived species such as mice, where significant effects on longevity via genetic variants are near commonplace. Show More Summary
The Buck Institute here provides a popular science look at links between cellular senescence and the development of Parkinson's disease. The proximate cause of the symptoms of Parkinson's is the diminishing numbers and function of a small collection of dopamine generating neurons in the brain. Show More Summary
In past years the Glenn Foundation for Medical Research has reinforced the mainstream of the aging research community with grants of a few million dollars apiece to establish or expand laboratories in many major universities and research centers. Show More Summary
Nor 70 the new 50 but people are still trying to sell that to us. If you pay too much attention to media chatter, you can easily be convinced that old age is a nice, smooth continuation of midlife. If...
Two of the many topics of interest found in the study of longevity are (a) the long-lived naked mole rat and (b) the processes by which the mammalian brain generates new neurons and connections to maintain itself. Today I'll point out...Show More Summary
Ending a relationship involves pain for both partners, regardless of who initiates the breakup. Although the well-known song proclaims there are 50 ways to leave your lover, the literature identifies 47. People high in compassionate love will be the most likely to use the least painful of these breakup strategies.
A researcher here runs the numbers to demonstrate an inverse correlation between autoimmune disease incidence and life expectancy. It is interesting to speculate on the mechanisms here, which are probably not going to turn out to beShow More Summary