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Elder Use of Marijuana

3 hours agoHealth / Aging : Time Goes By

[DISCLOSURE: I've been smoking pot recreationally since I was in high school with no ill effects I can see. I don't do so often nowadays because in my old age, it makes me cough too much. I haven't gotten around...

Projecting out Current Life Expectancy Trends to 2030

5 hours agoHealth / Aging : Fight Aging

I think it a given that trend projection at the present time is going to greatly underestimate gains in life expectancy over the next few decades. This present decade and the next encompass a transition from palliative and compensatory...Show More Summary

Is a Clone Born at Age Zero?

6 hours agoHealth / Aging : Fight Aging

In the overlap between research into aging and research into regeneration there is some interest in what exactly it is that happens between fertilization and later development of a zygote that enables old reproductive cells to produce young children. Show More Summary

An Interview with Aschwin de Wolf on Cryonics at LongeCity

16 hours agoHealth / Aging : Fight Aging

Aschwin de Wolf of Advanced Neural Biosciences and the Institute for Evidence-Based Cryonics (IEBC) is a noted advocate for cryonics as an industry and area of research. He was recently interviewed by the folk over at LongeCity, and as usual it makes for interesting reading. Show More Summary

What Happens When Narcissism Turns Malignant

Narcissism is one of the Dark Triad traits that also include psychopathy and Machiavellianism. New research that sadism brings its own unique contribution to the equation.

A novel principle to mobilize neurons for brain repair

Restorative neuroscience is a rapidly advancing scientific field considering our progressively aging society. Redirecting immature neurons that reside in specific brain areas towards the sites of brain damage is an appealing strategy for the therapy of acute brain injury or stroke. Show More Summary

The Risks of Current Approaches to Rebooting the Immune System

yesterdayHealth / Aging : Fight Aging

The present approaches to rebooting the immune system have shown considerable promise in treatment of autoimmune diseases such as multiple sclerosis. Unfortunately the current methods of immune destruction involve chemotherapy, which...Show More Summary

Identification of a Potential Autophagy Enhancement Drug

yesterdayHealth / Aging : Fight Aging

Researchers here note the identification of a drug candidate to enhance autophagy, a process of cellular housekeeping responsible for removing damaged proteins and structures in the cell. Enhanced autophagy is associated with many of...Show More Summary

The Media Meanders on the Topic of Enhanced Longevity

yesterdayHealth / Aging : Fight Aging

For various reasons, such as people promoting their books, the mainstream media has been giving more attention than usual these past few weeks to the topic of healthy life extension. The quality of the resulting articles is fairly low, as is usually the case. Show More Summary

SkQ1 Slows Accelerated Aging in Mitochondrial Mutator Mice

2 days agoHealth / Aging : Fight Aging

Mice engineered to generate a high level of deletion mutations in mitochondrial DNA exhibit accelerated aging. As in most cases of accelerated aging, we can debate whether or not it is correct to call it accelerated aging. The important...Show More Summary

A Diet of Old Tissues Modestly Shortens Life Span

2 days agoHealth / Aging : Fight Aging

In an interesting series of experiments, researchers found evidence for a diet of old tissues to modestly reduce life span in flies and mice. If speculating on specific mechanisms, we might look to the various forms of metabolic waste...Show More Summary

A Thank You. Presidents' Day. And More

2 days agoHealth / Aging : Time Goes By

Does anyone else have trouble tracking federal holidays after retiring? Sure, I have no problem with Independence Day, Thanksgiving Day and the other big ones. But today, Presidents' Day, regularly escapes me. One consequence is that I told at least...

Vitamin B3 prevents glaucoma in laboratory mice

In mice genetically predisposed to glaucoma, vitamin B3 added to drinking water is effective at preventing the disease. The vitamin administration was surprisingly effective, eliminating the vast majority of age-related molecular changes and providing a remarkably robust protection against glaucoma. Show More Summary

Fight Aging! Newsletter, February 20th 2017

3 days agoHealth / Aging : Fight Aging

Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and...Show More Summary

ELDER MUSIC: A Fifth of Classical Gas

3 days agoHealth / Aging : Time Goes By

FINAL DAY OF THE 2017 TGB DONATION DRIVE At last, you have reached the final day of the 2017 TGB donation drive. If you don't know what that is, you can find out details in last Monday's post. If you...

A Super-Quick Way to Determine Who’s Psychopathic

It certainly is of great value to be able to sniff out a psychopath. There are many possible tests and quizzes; the latest entry promises to be the quickest, and maybe the best.

INTERESTING STUFF – 18 February 2017

4 days agoHealth / Aging : Time Goes By

TIME GOES BY 2016 DONATION WEEK REMINDER It's almost over – just one more day of the annual TGB donation week. If you have been AWOL this week, you can learn more here. If you have donated, I thank you....

Discussions of Stem Cell Rejuvenation

4 days agoHealth / Aging : Fight Aging

Earlier this week I noticed a couple of very readable open access papers in which the authors discuss the potential for rejuvenation of stem cells as a means to address some aspects of aging. Reversing age-related stem cell decline has...Show More Summary

Elders, Stress and the U.S. Government

5 days agoHealth / Aging : Time Goes By

There is a lot to do today so let's start with the winners of the drawing for Norm Jenson's book, Mostly Anecdotal: Stories that we told you about on Wednesday. May I have a drum roll please. And the winners...

Examining Changes in Fat Tissue Metabolism with Aging and Calorie Restriction

5 days agoHealth / Aging : Fight Aging

Here researchers look at some of the changes wrought in the metabolism of fat tissue, both over the course of aging, and under conditions of calorie restriction. Calorie restriction is the practice of eating fewer calories while still obtaining optimal levels of micronutrients. Show More Summary

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