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Sirtuin Research Continues Ever Onward in Search of Relevance

last weekHealth / Aging : Fight Aging

As a result of failed commercial efforts a decade ago, research into sirtuins - particularly SIRT1 - in the context of aging is broader than it might otherwise be, and has a great deal of inertia. A lot of funding poured into this area,...Show More Summary

The Amateur Cancer Patient

Aside from a flu now and then, and a mystery illness 40 years ago that was never diagnosed but involved 11 days in hospital, I have never had a serious disease or condition until now. Throughout my adult years, when...

Pol III Inhibition Modestly Extends Life in Flies and Worms

last weekHealth / Aging : Fight Aging

As a general rule, a 10% extension of life in short-lived species is nothing of any great significance. There are an increasing number of methods shown to do this, such as the one noted here. Researchers have more than doubled the life...Show More Summary

An Example of a Pitfall in the Correlation of Excess Fat with Age-Related Disease

last weekHealth / Aging : Fight Aging

Terrible, slow moving age-related diseases that kill you also tend to make you lose weight along the way. Even the lengthy period of gradually increasing disability prior to full-blown disease can achieve that result. This point is very...Show More Summary

Aubrey de Grey Summarizes Rejuvenation Research at the MIT Technology Review

last weekHealth / Aging : Fight Aging

In this piece at the MIT Technology Review, Aubrey de Grey of the SENS Research Foundation summarizes the strategy of rejuvenation research based on periodic repair of the cell and tissue damage that causes aging. This is a philosophy...Show More Summary

There Will Be No Shortage of Geroprotector Drug Candidates

last weekHealth / Aging : Fight Aging

Portions of the research community are becoming quite proficient at churning out potential drug candidates for specific conditions based on processes that involve a lot more computation and modeling than actual laboratory work. The compound...Show More Summary

Obesity increases dementia risk

People who have a high body mass index (BMI) are more likely to develop dementia than those with a normal weight, according to a new study.

Gene variant that protects against Alzheimer's disease identified

Research details a novel and promising approach in the effort to treat Alzheimer's disease. Medical researchers have discovered a rare genetic variant that provides a protective effect for high-risk individuals -- elderly people who carry known genetic risk factors for Alzheimer's-- who never acquired the disease.

More than half of US children will have obesity as adults if current trends continue

If current trends in child obesity continue, more than 57 percent of today's children in the US will have obesity at age 35, according to a new study.

No Great Surprises in a Recent Study of Skin Aging

last weekHealth / Aging : Fight Aging

A recent study of skin aging brings no great surprises. The authors are focused on epigenetic changes that alter the rate of production of various proteins, and thus also alter the behavior and function of cells and tissues. People with...Show More Summary

8 Ways Your Inner Narcissist Leads You to Poor Decisions

Use these 8 research-based tips to guide you through making better decisions this holiday season when retailers are aiming for your weaknesses and your wallets.

8 Ways Insecurity and Narcissism Drive Your Urge to Shop

Use these 8 research-based tips to guide you through making better decisions this holiday season when retailers are aiming for your weaknesses and your wallets.

No evidence that gadolinium causes neurologic harm

There is no evidence that accumulation in the brain of the element gadolinium speeds cognitive decline, according to a new study.

The Life of a Bear (and an Old Woman)

One of my oldest blog friends, Darlene Costner, sent this clip a couple of weeks ago. It is from a 1988 French film, The Bear (L'Ours), written by Gerard Brach from James Oliver Curwood's novel and directed by Jean-Jacques Annaud......

Aging and the Unfolded Protein Response in the Endoplasmic Reticulum

last weekHealth / Aging : Fight Aging

The endoplasmic reticulum, like many structures in the cell, becomes dysfunctional in old tissues. Since it is involved in the later stages of the construction of properly formed proteins, this is one of the more problematic failures; degraded performance here has many secondary consequences. Show More Summary

Researchers Demonstrate a Larger Heart Muscle Patch, but Generating Blood Vessels Remains a Challenge

last weekHealth / Aging : Fight Aging

In the engineering of tissue grown from a cell sample, researchers are currently limited to building thin slices or small sections, no more than a few millimeters in thickness, the distance that nutrients can perfuse without a capillary network. Show More Summary

8 Ways Online Ads Appeal to the Inferior and Narcissistic

Use these 8 research-based tips to guide you through making better decisions this holiday season when retailers are aiming for your weaknesses and your wallets.

8 Ways to Build Your Self-Esteem to Resist Those Email Ads

Use these 8 research-based tips to guide you through making better decisions this holiday season when retailers are aiming for your weaknesses and your wallets.

8 Ways Online Retailers Prey on Your Feelings of Inferiority

It's feelings of inferiority that retailers try to tap into when pulling you toward their constant online lures. Use these 8 research-based tips to guide you into better decisions.

This Giving Tuesday, Help to Bring an End to Age-Related Disease, Pain, and Death

last weekHealth / Aging : Fight Aging

It is Giving Tuesday once more, a time to look ahead and consider how we can improve the future of humanity through philanthropy: to join forces and fund the projects that will build a better tomorrow. A time to not just think about it, but to take action - to make a difference. Show More Summary

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