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Major Mouse Testing Program Hosts an AMA at /r/futurology Today

last weekHealth / Aging : Fight Aging

The researchers and advocates of the Major Mouse Testing Program will be answering your questions in an /r/futurology AMA ("Ask Me Anything") event later today. The organization is presently raising funds via crowdfunding in order to...Show More Summary

Heart Rate Variability and Pacemaker Cell Deterioration in Aging

last weekHealth / Aging : Fight Aging

Researchers here report on the details of pacemaker cell decline in aging. These cells drive the heartbeat, but as is the case for all tissues, they and their environment become damaged and dysfunctional in later life. Signaling mechanisms...Show More Summary

Fight Aging! Newsletter, May 16th 2016

last weekHealth / Aging : Fight Aging

FIGHT AGING! NEWSLETTER May 16th 2016 Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent...Show More Summary

Making a Good Impression Depends on Who You Want to Impress

If you had your choice, would you rather seem warm and caring or knowledgeable and intelligent? To pick the best strategy, consider who it is you’re trying to impress.

INTERESTING STUFF – 14 May 2016

NEW YORK TIMES OBITUARIES I still remember my surprise more than half a century ago when, at a radio station, I saw a stack of audio cassettes with such labels as “Eisenhower Obit.” Not that I had thought about it...

Yes, in Principle Aging can be Controlled and Altered to a Large Degree

last weekHealth / Aging : Fight Aging

The popular science article I'll point out here is written from a programmed aging point of view, in which - to simplify greatly - epigenetic change is considered to be the root cause of aging, changing the operation of cellular metabolism so as to generate damage, dysfunction, and death. Show More Summary

Drawbacks to Healthy Life Extension? What Drawbacks?

last weekHealth / Aging : Fight Aging

Gaining more years of healthy life through progress in medicine is a change with no downside, to my eyes. That many people strive to find problems, and that many more people seem disinterested in gaining more years, disinterested inShow More Summary

Autophagy Required for Cancer Metastasis

last weekHealth / Aging : Fight Aging

If researchers can shut down metastasis by targeting a fundamental mechanism common to all or even many cancers, then cancer becomes much more manageable and much less threatening. That is why it is worth paying attention to research that might produce useful results along those lines. Show More Summary

How Time Flies – Or Not Sometimes

Most old people agree that the older we get, the faster time goes by. But in under an hour early Tuesday morning, I had a good lesson in just how slowly time can pass in certain circumstances. By 8AM, I...

Why Do So Few Wealthy, Sick Individuals Fund Medical Research to Treat Their Conditions?

last weekHealth / Aging : Fight Aging

There are a lot of people who have both a medical condition and a lot of wealth - tens of millions of dollars or more. In this day and age, a fraction of that wealth is enough to produce a prototype treatment from scratch for many classes of condition, if you are willing to wait the decade or two that low-cost basic science takes to run its course. Show More Summary

An Example of Present Attitudes on Treating Aging in the Research Community

2 weeks agoHealth / Aging : Fight Aging

This open access paper is quite representative of attitudes in much of the aging research community. Scientists are excited by the obvious burst of progress and possibilities, and changing attitudes in the research community let them...Show More Summary

Reporting on a Recent Study of Mitochondrially Targeted Antioxidant SkQ1

2 weeks agoHealth / Aging : Fight Aging

Here, researchers report on a recent study of the ability of mitochondrially targeted antioxidants to modestly increase healthy life span in lower animals such as the flies used here. Mitochondria are important in the progression ofShow More Summary

Help Crowdfund Senescent Cell Clearance as a Therapy for Aging at the Major Mouse Testing Program

2 weeks agoHealth / Aging : Fight Aging

The cadence of SENS rejuvenation research fundraising this year will be a little different from that of past years. There will be more groups involved and more smaller initiatives running through existing crowdfunding sites for a start. Show More Summary

Towards Stem Cell Medicine that Doesn't Involve Stem Cell Transplants

2 weeks agoHealth / Aging : Fight Aging

In all but the most aged and damaged individuals, the beneficial effects of much of the present generation of stem cell transplant therapies could in principle be produced by stem cell populations already present in the body. These cells just need the right signals and instructions to be put to work. Show More Summary

Negligibly Senescent Species in the Context of Longevity Science

2 weeks agoHealth / Aging : Fight Aging

This popular science article focuses on the study of negligibly senescent species in the context of work aimed at adjusting the course of human aging. There is at least one negligibly senescent mammal, the naked mole-rat, but it seems...Show More Summary

Will I Live Long Enough to Use All This?

2 weeks agoHealth / Aging : Time Goes By

Have you seen those human interest stories that turn up now and then about super-dooper coupon clippers? You know, the mothers who feed a family of six for $3.27 a month because they are such world-class coupon collectors? I have...

Help to Crowdfund More Progress Towards DRACO Universal Antiviral Therapies

2 weeks agoHealth / Aging : Fight Aging

A new crowdfunding effort is running to gather funds and support to push forward with DRACO antiviral technology. DRACO stands for double-stranded RNA activated caspase oligomerizer, a class of designer molecules that can selectively destroy cells that are hosting viruses. Show More Summary

How to Get Along With People You Don’t Like Very Much

As hard as you try, you may find it impossible to get along with certain family members, coworkers, or acquaintances. This simple guide will give you the tricks you need.

GADD45? in the Mechanisms of Fasting and Calorie Restriction

2 weeks agoHealth / Aging : Fight Aging

Lower calorie intake, while still obtaining required levels of micronutrients, has long been demonstrated to improve near all measures of health, and leads to better quality of life, and modestly slows aging. A higher calorie intakeShow More Summary

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