Chronic inflammation is important in neurodegenerative conditions such as Alzheimer's disease, but how much of that is due to age-related dysfunction of the immune system versus the presence of pathogens? Inflammation is a necessary part of the immune response when it is working correctly, after all. Show More Summary
Cancer is thought to be a disease of aging because we accumulate randomly distributed damage to nuclear DNA as we age. The older you are the more of this damage you have. Sooner or later the right combination of mutations occur in aShow More Summary
Common genetic variants contribute to individual differences in longevity when considered statistically across thousands of individuals and decades of their lives. But even statistically common genetic variations are not particularly important until later life. Show More Summary
The way we feel is, for better or worse, reflected by our nonverbal communication. The way you reveal, understand, and manage your emotions can mean the difference between successful and unsuccessful interactions from casual to intimate long-term relationships. read more
Hardly a day goes by that you don't bump into the phrase, successful ageing. Well, you do if you read as much about growing old as I do and it is one of the most empty phrases I know. What...
Comparative biology is a matter of studying differences between species that might provide insight into how particular cellular mechanisms of interest actually work - or might be altered so as to work better. The world has many species...Show More Summary
Paul Allen is funding a new large-scale life science project to follow up on the Brain Atlas. This time the goal is to fill in the unknown reaches of cellular metabolism: Billionaire Paul Allen has a new target for scientific philanthropy: Unraveling the inner workings of human cells. Show More Summary
As I'm sure you're all aware, back in October Fight Aging! launched a matching fundraiser in support of the work of the SENS Research Foundation. Together Christophe and Dominique Cornuejols, Dennis Towne, Håkon Karlsen, Jason Hope,Show More Summary
Many of you sent a link to the Wall Street Journal Encore section titled “Why Everything You Think About Aging May be Wrong.” The sections of the report are divided into six myths about depression, cognitive decline, employment productivity, loneliness,...
In the field of tissue engineering at present the work on simpler tissues and smaller tissue sections is the closest to widespread commercial realization. Most of the leading lines of research and development involve the use of decellularization,...Show More Summary
The Golgi apparatus is a large structure in the cell that sets up transport of proteins to cell components by packaging and labeling the proteins to ensure they are sent to specific destinations. It is also involved in numerous other...Show More Summary
This Sunday Elder Music column was launched in December of 2008. By May of the following year, one commenter, Peter Tibbles, had added so much knowledge and value to my poor attempts at musical presentations that I asked him to...
People make excuses for all sorts of reasons, and although we’ve come to accept this as an ordinary fact of life, it doesn’t make it any easier to put up with ones from the people we love. These 5 tips will help reduce the likelihood that the person you love will use on one you. read more
People make excuses for all sorts of reasons, and although we’ve come to accept this as an ordinary fact of life, it doesn’t make it any easier to put up with ones that we know aren’t real. These 5 tips will help you make phony excuses less of a problem in your life and in the lives of people you care about. read more
OLD NFL COACHES WINNING The Arizona Cardinals was a struggling team two years ago when they hired the third oldest head coach in the history of the NFL. Then, that guy hired three assistant coaches who are even older than...
It has been some years since sarcopenia was coined as a name for the characteristic loss of muscle mass and strength that occurs with aging, one of many attempts - some successful - to carve off an aspect of aging and obtain regulatory approval to work on treating it. Show More Summary
An increasing number of websites – Reuters, Popular Science, the Chicago Sun-Times among them - have turned off their online comments sections. According to a story at World News Publishing Focus, one reason is ”The arduous task of moderating the...
When considering the impact on life expectancy and long-term health the data tells us that obesity and smoking are in the same ballpark. Here is a recent research publication that puts some numbers to the very real costs of being overweight. Show More Summary
This article talks generally about the current directions in aging research and recent developments while managing to entirely avoid mention of SENS-style rejuvenation research. Reading this you'd think that the only possible approach...Show More Summary
I rarely write obituaries, because once you start where do you stop? Perhaps a hundred and fifty thousand lives are lost every day, most due to aging and its consequences, and it isn't just the few people you happened to exchange emails with who are worthy of notice. Show More Summary