I noticed this study today which reinforces the well-known correlation between wealth and longevity, but more strongly reinforces the point that people age at different rates. If you have developed more pronounced age-related disease or disability at 70, then your odds of reaching 90 are not so good in comparison to your more healthy peers. Show More Summary
Researchers have demonstrated that acarbose, a drug used to treat type 2 diabetes, extends life in mice. This should probably be taken as speculative until more studies are run, as another treatment for type 2 diabetes, metformin, has erratic results on life span in rodent studies. Show More Summary
Cryonics is the science and industry of preserving the physical structure of the mind on death, indefinitely preventing its decay through low-temperature storage. At some point future technology will be capable of restoring a preserved...Show More Summary
The proteome is the set of all proteins expressed by an organism; stability in expression levels over time indicates fewer changes in the operation of metabolism, which might also indicate slower aging. Looking at proteomic stability...Show More Summary
On Monday, Democratic Senator Elizabeth Warren of Massachusetts gave an important speech on the floor of U.S. Senate about our retirement crisis. It's only about five-and-a-half minutes and if you have watched it, please do: As you know, to end...
This open access review paper on the characteristic changes of aging that occur in lung tissue and function illustrates the importance of immune system decline as a component of the frailty of aging. It impacts all of the major organs. Show More Summary
A fair-sized fraction of present aging research relates to epigenetic changes that occur with aging. Epigenetics is the study of gene expression, the process by which proteins are produced from genetic blueprints, and the many different ways in which gene expression changes in response to health and environmental factors. Show More Summary
Some of you were nice enough to say kind things about my appearance in this photograph taken during the conference I attended at the Business Innovation Factory in Providence, Rhode Island a couple of weeks ago. If you have been...
A hormetic process is one in which a little damage spurs damage repair mechanisms into an extended effort, leading to a net positive gain. A number of means of extending life in laboratory animals involve hormesis, and many of thoseShow More Summary
Calorie restriction extends life and improves health in nearly every species tested to date. Sensing of levels of methionine, an essential amino acid, appears to be one of the controlling mechanisms involved in the shift of metabolism into a state that ensures greater longevity. Show More Summary
One of the most important divides in the aging research community today is that between the view of aging as a result of the stochastic accumulation of cellular and molecular damage and the view of aging as resulting from an evolved genetic program. Show More Summary
When you hear the term “role model,” you’re likely to conjure up an image of a young child looking up to a parent, teacher, or older sibling. You may think we grow out of our need for these inspirational figures in our lives, but as it turns out, having a role model can provide important life lessons, no matter what your age. read more
In the United States, beauty and aging are believed not to be related. But that is only because our idea of beauty is so crabbed and stunted – applied only to physical beauty and then to only one kind: youthful....
Using gene therapy to alter levels of specific proteins in a targeted fashion is an intermediary advance in medicine for age-related conditions. Practical applications of this technology should provide an improvement over what came before,...Show More Summary
An example of early stage progress towards building new kidney tissue to replace aged or diseased kidneys, or for use in bioartificial kidney devices: For the first time, [researchers] have generated three-dimensional kidney structures...Show More Summary
As you might be aware, the SENS Research Foundation is the leading light when it comes to funding the most meaningful research into human rejuvenation. The Foundation staff have the plan, the allied network of researchers and laboratories, and are gathering the necessary funds from philanthropists and a grassroots community of supporters. Show More Summary
When a news alert box popped onto my computer screen that Nobel Prize-winning author Doris Lessing had died at her home in London on Sunday, I stopped what I was doing and thought about how I have reached the age...
Targeted killing of cancer cells is the future of cancer treatment, an approach that results in better outcomes and fewer side-effects. Numerous different mechanisms to target and destroy specific types of cell have been developed in...Show More Summary
Scientist Steven Austad is well known in the field of aging research. For the past few years he has penned a column for a Texas paper - the sort of public engagement that I'd like to see more researchers undertake on a regular basis....Show More Summary
This Sunday Elder Music column was launched in December of 2008. By May of the following year, one commenter, Peter Tibbles, had added so much knowledge and value to my poor attempts at musical presentations that I asked him to...