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Another Possible Cancer Suppression Mechanism in Naked Mole Rats

last weekHealth / Aging : Fight Aging

Besides living for nine times longer than other, similarly sized rodent species, naked mole rats are also highly resistant to cancer, to the point at which only a handful of cases have ever been observed. The scientific community is seeking the roots of this cancer resistance to see if the mechanisms involved can form the basis for human therapies. Show More Summary

Investigating CD38 and NAD in Aging

last weekHealth / Aging : Fight Aging

Of late, there has been a growing interest in exploring mechanisms related to nicotinamide adenine dinucleotide (NAD) and the way in which their operation changes over the course of aging. This research has grown out of the last decade...Show More Summary

A So Far Weak Approach to Stimulating Autophagy to Slow Aging

last weekHealth / Aging : Fight Aging

The research materials for today offer one example of numerous parallel efforts to find a mechanism and drug candidate that can stimulate autophagy and thereby modestly slow the progression of aging. It is too early to say whether this...Show More Summary

The Thought Process That Ruins Relationships

It's fulfilling to feel secure in your intimate relationship, but the more you seek that fulfillment, the more problematic that relationship may become.

Suggesting that Higher Levels of IGF-1 Might Slow Atherosclerosis Progression

last weekHealth / Aging : Fight Aging

Researchers have found that a reduced level of insulin-like growth factor 1 (IGF-1) in mice accelerates the progression of atherosclerosis, one of the more dangerous of age-related cardiovascular issues. Atherosclerosis involves theShow More Summary

In Search of Early, Asymptomatic Stages of Alzheimer's Disease

last weekHealth / Aging : Fight Aging

Many signs of age-related disease start as early as the 30s, damage that is asymptomatic and minimal, but nonetheless exactly the same type of dysfunction that will later, when present to a much greater degree, cause age-related disease, frailty, and death. Show More Summary

Eliminate SHIP? This is Important, My Friends

At lunch last week with a friend who turns 65 early next year, we spent a great deal of time discussing Medicare choices. It's not an easy program to sort out, particularly when you are first signing up. Serendipity is...

Fight Aging! Newsletter, June 20th 2016

last weekHealth / Aging : Fight Aging

FIGHT AGING! NEWSLETTER June 20th 2016 Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent...Show More Summary

What Your Face Tells the World About You

We are constantly judged by our facial appearance. Although you can’t change your basic features, you do have the ability to change the messages your face communicates.

Be a Better Romantic Partner with This Simple Mental Trick

Inward-oriented thinking, or introspection, is a key aspect of mindfulness. Neuroscience shows us how introspection can help you understand the one you love as well as yourself.


JOHN OLIVER AND SAMANTHA BEE When John Oliver's most recent Last Week Tonight show on HBO was broadcast last Sunday night, fewer than 24 hours has passed since the attack at the Pulse nightclub in Orlando. Very little was known...

To What Degree is Alzheimer's a Lifestyle Disease?

2 weeks agoHealth / Aging : Fight Aging

Type 2 diabetes is the archetypal lifestyle disease, a metabolic dysfunction run out of control to the point at which it disrupts the crucial mechanisms of insulin metabolism. Diabetes isn't accelerated aging, but it has many of the same consequences when viewed from the high level: more damage, more disease, higher mortality. Show More Summary

Stem Cells from Young Mice Heal Stomach Ulcers in Old Mice

2 weeks agoHealth / Aging : Fight Aging

When it comes to the question of whether young stem cells and a young tissue environment are necessary for the success of stem cell therapies, there is evidence to support all of the possible answers. It is a confusing picture at the moment, and it is very possible that the answer varies by cell type. Show More Summary

Progress in Tissue Engineered Bone, Matching Natural Bone Structure

2 weeks agoHealth / Aging : Fight Aging

Researchers have announced progress in the production of larger sections of bone for transplantation. Once transplanted, the new bone serves as a template to provoke further regeneration to match the structure of the natural bone that is replaced. Show More Summary

When are Aches and Pains Serious?

2 weeks agoHealth / Aging : Time Goes By

Long-time TGB reader Jean Gogolin emailed recently with this query: ”I have a good friend who's 75 and has been practicing yoga for years. The other day she was complaining to her yoga teacher about her various aches and pains...

Replacing Neural Stem Cells in the Aging Hippocampus

2 weeks agoHealth / Aging : Fight Aging

Today I'll point out progress towards an as yet unrealized category of stem cell treatments involving the wholesale replacement of entire stem cell populations and their niches, to remove age-related damage and sustain tissue maintenance for the long term. Show More Summary

Restoring Osteocalcin Levels Reverses Age-Related Decline in Exercise Capacity

2 weeks agoHealth / Aging : Fight Aging

Osteocalcin levels decline with age, one of many age-related changes in production of specific proteins. Researchers here demonstrate that introducing additional osteocalcin restores age-related loss of exercise capacity in mice. This...Show More Summary

You Know You Need More Sleep. This May Be the Way to Get It.

Experts say we’re all sleep deprived, but it’s possible that those experts are creating the very deprivation they’re trying to prevent.

Human GDF11 Does Not Decline With Age

2 weeks agoHealth / Aging : Fight Aging

Researchers have in the past couple of years shown that GDF11 levels decline with age in mice, and that restoring youthful GDF11 in old mice improves numerous measures of health. The mechanism involved may be increased stem cell activity. Show More Summary

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