There are a number of people, researchers and advocates, in the longevity science community who have a good understanding of present research and knowledge, but who then build on that understanding to assemble what look to me to be completely the wrong conclusions about how best to proceed towards extending healthy life spans. Show More Summary
One of the ongoing themes in stem cell research is the discovery that numerous tissues thought to be static or poor at regeneration are in fact generating new cells, and can in fact regenerate under some circumstances. If the rudiments...Show More Summary
Since it was announced more than two weeks ago, you are likely to be way ahead of me about this: on Monday 27 October, the French cosmetic company L'Oreal named 69-year-old actor Helen Mirren their latest spokesperson for the U.K......
There are two choices: do nothing and probably age to death, or support research into longevity science and live for much longer in good health if it is successful. Since you are here and reading this, the dice are already rolling for the rest of your life. Show More Summary
The search for longevity-associated genes continues, and the evidence taken as a whole suggests that the situation is very complex. So far the evidence strongly suggests that potentially hundreds or thousands of genes each provide aShow More Summary
The SENS Research Foundation is perhaps the only group in the world to presently focus on organizing, advocating, and carrying out research into the biotechnologies required for treatments capable of reversing degenerative aging. The pains and frailties of aging are the consequence of unrepaired damage to cells and tissues. Show More Summary
The practice of heterochronic parabiosis, linking the circulatory systems of old and young mice and observing the results, produces measurable beneficial changes in the tissues of the old mice. Researchers have identified a few proteins...Show More Summary
Evidence for blood group differences to be meaningfully involved in natural variations in longevity is nebulous at best. Nonetheless, papers emerge every so often on this topic to theorize and collect more evidence, but continue to reinforce...Show More Summary
Kentucky Senator and 2016 presidential hopeful, Rand Paul, thinks so. Here is what he told Politico this week in an interview with Mike Allen: “'I think all the polls show if [Senator Hillary Clinton] does run, she’ll win the Democrat...
Aubrey de Grey is originator of the SENS rejuvenation research programs and presently Chief Science Officer at the SENS Research Foundation, the umbrella organization dedicated to ensuring that therapies to treat and reverse degenerative aging are developed as soon as possible. Show More Summary
In a close relationship, it’s natural for partners to expect to receive both emotional and practical care and support. People also judge whether their partners are “good enough” for them. These 19 items will tell whether a sense of emotional entitlement will spell doom or boom for your relationship’s future. read more
Mitochondria are bacteria-like organelles that swarm in their thousands in each of our cells, and they are important in aging because they can suffer forms of damage that negatively impact the functionality of their host cell. The mitochondrial...Show More Summary
A few weeks ago The New York Times published a splashy feature containing photo portraits and short interviews with a baker's dozen of people who have continued to work full speed into their ninth and tenth decades. The long-time, former...
One of the roles of the enzyme telomerase is to extend the repeating telomere DNA sequences at the ends of chromosomes, thus lengthening the replicative life span of cells. Telomere length is a part of the clock mechanism limiting the life span of ordinary cells, and it decreases with each cell division. Show More Summary
Aging research is still mostly a matter of investigation, gathering data and validating theories without a hint of any intent to build treatments to help the aged. This terrible state of affairs is changing, however, and the prospects...Show More Summary
Narcissists may seem as though they’re completely in love with themselves, but at the root of their inflated egos are deeply-held feelings of inferiority. Arguments and criticism therefore bring out their worst fears. Perhaps instead of self-love we should think of narcissists as experiencing self-hate. read more
The ageism of pundits and the press, of movies and television, even comedians, is so ubiquitous that most Americans don't believe there is such a thing. That makes it big news (on this website, if not elsewhere) when a professional....
Present work on artificial blood tends to focus on narrow areas of functionality in which short-term augmentation of the capabilities of natural blood are useful, such as oxygen transport and clotting. From these diverse paths a wholly...Show More Summary
When creating patient-matched cells for use in regenerative therapies the present approach is to generate pluripotent cells, such as induced pluripotent stem cells, from an easily obtained sample, and then guide those cells to differentiate into the desired cell type. Show More Summary
This Sunday Elder Music column was launched in December of 2008. By May of the following year, one commenter, Peter Tibbles, had added so much knowledge and value to my poor attempts at musical presentations that I asked him to...