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Measurable Amyloid Buildup Occurs Significantly Before Alzheimer's Disease

last weekHealth / Aging : Fight Aging

Named and formally recognized age-related diseases are the late stages of processes of damage that start much earlier in life. So it is never a surprise to see that specific forms of damage strongly associated with any one specific age-related...Show More Summary

Recent Research into the Details of Cellular Senescence

last weekHealth / Aging : Fight Aging

Today's papers are representative of present investigations that aim primarily to expand our knowledge of the details of cellular senescence. This is as opposed to efforts to immediately produce treatments that can address the impact of senescent cells on health. Show More Summary

10 Ways to Cope with Life's Unpleasant Tasks

Life often presents us with tasks that we’d rather not have to tackle. When faced with the inevitable, new research suggests how to make the whole process that much easier.

The One Thing Men Do That Irritates Women the Most

A man who presumes he knows more than the women around him can, without realizing it, engage in this one behavior sure to annoy his female companions. New research shows why.

An Update on the Effects on PAPP-A Knockout on Longevity in Mice

last weekHealth / Aging : Fight Aging

Deletion of pregnancy-associated plasma protein-A (PAPP-A) is one of a number of genetic alterations that have been used to produced lineages of long-lived mice. For researchers interested in translating this sort of discovery into treatments...Show More Summary

Another Potential Approach to the Creation of Tissue Engineered Cartilage

last weekHealth / Aging : Fight Aging

Cartilage is a comparatively simple, homogeneous tissue, and the medical community has a great deal of experience in treating cartilage injuries, so it is an obvious place to start for tissue engineers. Creating cartilage that has the...Show More Summary

I'm Not Dead Yet as a Path to Calorie Restriction Mimetics

last weekHealth / Aging : Fight Aging

INDY, I'm Not Dead Yet, is one of the earliest of longevity-associated genes to be documented. Researchers uncovered its effects in flies

I'm Not Dead Yet, a Review

last weekHealth / Aging : Fight Aging

INDY, I'm Not Dead Yet, is one of the earliest of longevity-associated genes to be documented. Researchers uncovered its effects in flies

From Mystery Malady to Pancreatic Cancer

As I mentioned on Friday, TGB reader dkzody last week commented that she had believed pancreatic cancer is hard to diagnose and wondered what my “mystery malady” was. Today, I'll tell you my experience with that mystery and my eventual...

Ghrelin Knockout Mice Eat Less But Fail to Live Longer as a Result

last weekHealth / Aging : Fight Aging

One of the many interesting but unresolved questions relating to calorie restriction and its beneficial effects on health and longevity is the role played by ghrelin. This hormone regulates appetite, but also has a range of other effects on metabolism. Show More Summary

Regeneration of Structured, Full-Thickness Skin, Including Hair Follicles

last weekHealth / Aging : Fight Aging

The tissue engineering company PolarityTE is claiming regrowth of correctly structured skin in pigs, incorporating hair follicles and various glands. The press release and company website are light on some of the more interesting details,...Show More Summary

Fight Aging! Newsletter, June 12th 2017

last weekHealth / Aging : Fight Aging

Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and...Show More Summary

ELDER MUSIC: Jazzical Gas

This Sunday Elder Music column was launched in December of 2008. By May of the following year, one commenter, Peter Tibbles, had added so much knowledge and value to my poor attempts at musical presentations that I asked him to...

Are Young Women With Older Men Looking for a Daddy?

Relationships with a significant age gap almost always trigger raised eyebrows. Research helps to determine whether those raised eyebrows are justified.

Are Young Women with their Older Men Looking for a Daddy?

Relationships with a significant age gap almost always trigger raised eyebrows. Research on the dynamics of older men-younger women shows if those raised eyebrows are justified.

INTERESTING STUFF – 10 June 2017

2 weeks agoHealth / Aging : Time Goes By

As you may imagine, since the diagnosis of pancreatic cancer and preparation for the coming surgery, I have not had a lot of time to collect material for this weekly compilation of “stuff.” But here is a shorter-than-usual list of.....

Advocacy for the Importance of Mitochondrial Function in Aging

2 weeks agoHealth / Aging : Fight Aging

The open access paper I'll point out today should be taken as an opinion piece rather than something more rigorous, I think. The authors link together a few findings from past years in order to make an argument about some of the specifics of mitochondrial function and its importance in aging. Show More Summary

The Classification and Screening of Geroprotector Drug Candidates

2 weeks agoHealth / Aging : Fight Aging

One faction in the aging research community defines drugs that modestly slow aging as "geroprotectors," and maintains an online database of studies and results for such drug candidates. These drug candidates generally work through alterations...Show More Summary

Some Reason for Hope

2 weeks agoHealth / Aging : Time Goes By

Although I could argue the point, it is possible there is always reason for hope and I found that on Wednesday during my consult with the surgeon and his team. Having decided that formality is a good posture to adopt...

A Report from the 2nd Scripps Symposium on the Biology of Aging

2 weeks agoHealth / Aging : Fight Aging

This open access paper reports on the proceedings at the 2nd Scripps Symposium on the Biology of Aging held earlier this year. Like much of the field now, the focus in unabashedly on intervening in the aging process, which is good to see. Show More Summary

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