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More SIRT7 Improves Aged Stem Cell Regenerative Capacity

last weekHealth / Aging : Fight Aging

There is comparatively little study of sirtuin 7 (SIRT7) in comparison to the better known and greatly overhyped sirtuin 1 (SIRT1). All members of the sirtuin family have broad influence over a range of fundamental cellular processes,...Show More Summary

A Novel Approach in Engineering T Cells to Attack Cancer

last weekHealth / Aging : Fight Aging

A broad range of methods are under development to engineer T cells that can selectively attack cancer cells. If aggressive enough and selective enough, the immune system should in theory be able to tame and destroy most cancers, but the devil is in the details as is always the case in these matters. Show More Summary

Tissue Engineering of Lung and Gut Sections

last weekHealth / Aging : Fight Aging

The first practical outcome of tissue engineering research is not therapies, but rather improved tools for further scientific work in this and other fields. At present the structured tissue sections created in the laboratory are largely...Show More Summary

Considering the Path to Curing Blindness

last weekHealth / Aging : Fight Aging

The most prevalent causes of blindness are degenerative and associated with aging, the result of loss of cells and structure in the retina. There are numerous other causes, including optic nerve damage that can result from trauma, but these are fortunately less common. Show More Summary

Wise and Wily Old People

One of the good things the ageing of the huge baby boomer generation has spawned is an upsurge in research about old people, particularly brain and cognition research, and I follow it closely. Well, as much as possible. Most study.....

MicroRNAs Promote Heart Regeneration

last weekHealth / Aging : Fight Aging

Researchers have discovered a novel approach to spur greater regeneration in heart tissue: The heart tissue of mammals has limited capacity to regenerate after an injury such as a heart attack, in part due to the inability to reactivate a cardiac muscle cell and proliferation program. Show More Summary

At Some Point the "Anti-Aging" Industry Will Stop Producing Junk and Nonsense, and Will Actually Sell Meaningful Treatments

last weekHealth / Aging : Fight Aging

It is perfectly possible to build a tremendously successful business while failing to deliver on any of the initial motivating goals and ideals. The modern "anti-aging" industry is a perfect example of this point, written thousands of times over in the careers of salespeople and founders. Show More Summary

Why We Remember Things the Way We Want to Remember Them

When public figures erroneously report on events that didn’t actually happen in their lives, the whole world knows about it. However, false memories are a common occurrence in everyone’s day-to-day thinking. Remembering what you want to remember may be more a matter of identity than of failing memory.

Dying of Old Age Doesn't Feel So Great

last weekHealth / Aging : Fight Aging

There are a surprisingly large number of studies on personality traits and psychological states as they relate to health status in aging. I can't help but feel that all those funds should perhaps have gone towards generating more practical outcomes in the sciences, but it is what it is. Show More Summary

Crabby Old Lady on (Literally) Dying of Boredom

On Monday's post about Donald Hall's Essays at Eighty, Crabby Old Lady made particular note of a couple of readers who picked up and ran with the poet's thought about what bores him: ”You know what I find boring?” commented...

Targeting Nitric Oxide Metabolism in Calorie Restriction Mimetics

last weekHealth / Aging : Fight Aging

Calorie restriction mimetic treatments are those that recreate at least some part of the calorie restriction response. Calorie restriction with optimal nutrition alters near every measure of metabolism and slows near every measure of...Show More Summary

Continued Interest in Drugs that Might Slightly Slow Aging

2 weeks agoHealth / Aging : Fight Aging

Research institutions are willing to pour comparatively large sums into the pursuit of existing already developed and approved drugs that might, possibly, have some marginal, tiny effect on the course of degenerative aging. This is one...Show More Summary

What's Your Online Dating IQ?

It’s becoming socially more acceptable to admit to finding a mate online, but there remain many misconceptions about online dating. Find out your online dating IQ with this 8-item quiz that separates myth from reality.

The Surprising Facts about Online Dating

It’s becoming socially more acceptable to admit to finding a mate online, but there remain many misconceptions about online dating. Find out what you know, and don't know, about online dating sites with this 8-item true-false quiz.

TOM40 and Neurodegeneration

2 weeks agoHealth / Aging : Fight Aging

Mitochondria, the power plants of the cell, are important in aging. They are the descendants of symbiotic bacteria and contain their own DNA, separate from that in the cell nucleus. This mitochondrial DNA is just a remnant, however, as over the course of evolutionary time most of its genes have moved to the nucleus. Show More Summary

Data on Brain Aging and Early Signs of Alzheimer's Disease

2 weeks agoHealth / Aging : Fight Aging

The brain is impacted by the processes of degenerative aging for decades before the damage rises to noticeable levels. When the technologies exist to repair this damage, treatments should ideally begin in the middle of life, not wait until there are obvious signs of degeneration. Show More Summary

A Reason Old People Forget Things

2 weeks agoHealth / Aging : Time Goes By

About ten days ago, I wrote about being so forgetful now that I had gone to the store with only one item in mind and got home with six other things but not the apples I intended. According to the...

A Long Interview with Aubrey de Grey on London Real

2 weeks agoHealth / Aging : Fight Aging

Scientist and advocate Aubrey de Grey is the co-founder of the SENS Research Foundation, one of the most important organizations in aging research today, given its goal of turning the focus of the scientific community towards the implementation of rejuvenation biotechnology. Show More Summary

Failing Autophagy and Immune System Aging

2 weeks agoHealth / Aging : Fight Aging

Autophagy is one of the housekeeping processes responsible for recycling damaged mechanisms and structures in cells before they can cause further harm. A type of organelle called the lysosome performs the recycling, but lysosomal activity...Show More Summary

A Look at Peter Thiel's Biotechnology Investments

2 weeks agoHealth / Aging : Fight Aging

Investor and philanthropist Peter Thiel has given millions to support the rejuvenation biotechnology research programs funded by the SENS Research Foundation and Methuselah Foundation before it. He was one of the first wealthy individuals...Show More Summary

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