In the context of ongoing work on the beneficial effects of young ovaries in old mice, it is interesting to note that researchers have now managed to engineer functional mouse ovary tissue that produces eggs. The starting point was a cell sample, converted into induced pluripotent stem cells. Show More Summary
Researchers here identify a protein that increases regeneration in the central nervous system following injury, or to restore lost plasticity and ability to adapt in later life. Spurring greater regrowth of damaged nerves is of great interest to the research community, and a range of approaches are underway at various stages of development. Show More Summary
We’ve all come to know about defense mechanisms, but usually from the perspective of Freudian theory. This new view redefines nine of them in a more rational manner.
When it comes to the scope of history, the state of the present, and the future ahead, most people are overly pessimistic. Millennialism never really goes away. The past is seen in rose-tinted hues, the present is experienced against...Show More Summary
A nonsteroid anti-inflammatory drug used for treating colds suppresses the spread of bladder cancers and reduces their chemoresistance in mice, raising hopes of a future cure for advanced bladder cancers, report researchers.
It is always a good idea to look closely at the biochemistry involved in any potential Alzheimer's disease therapy that shows promise in mouse models. There is perhaps more uncertainty for Alzheimer's than most other age-related conditions...Show More Summary
Researchers here demonstrate a method of interfering in the spread of alpha-synuclein aggregates, an approach that may slow the progression of synucleopathies such as Parkinson's disease. Like a number of other age-related neurodegenerative...Show More Summary
Last week, TGB reader, Elizabeth Archerd contacted me with a topic suggestion for Time Goes By: ”...can we talk about how to manage home cooking as we age? “...My eating habits are great, according to every medical person I know,...
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and...Show More Summary
This Sunday Elder Music column was launched in December of 2008. By May of the following year, one commenter, Peter Tibbles, had added so much knowledge and value to my poor attempts at musical presentations that I asked him to...
You may have a feeling that you can’t quite identify in meeting someone for the first time. New research shows which signals you respond to, and why.
One of the more recent innovations in calorie restriction research has nothing to do with the science, and everything to do with figuring out how to pull more funding into the field. There is never enough funding for research in anyShow More Summary
BOB DYLAN WINS NOBEL PRIZE IN LITERATURE On Thursday, the winner of the Nobel Prize in Literature was announced in Stockholm and it was one of our generation – the poet/troubador Bob Dylan, age 75. Here is the moment when...
Not so very many years ago it was noted that transplanting young ovaries into old mice resulted in extended life. There is still no good understanding of why this happens, and which of the numerous changes produced by this transplantation...Show More Summary
A supporter recently asked the SENS Research Foundation staff whether the implementation of rejuvenation therapies that follow the SENS model of damage repair would prevent the development of cancer, since cancer is predominantly an age-related disease. Show More Summary
RONNI HERE: Remember last month when I told you that my friend Judith Graham, a trustworthy and respected reporter on the “age beat,” had begun a new column at one of the most trustworthy and respected health websites we have,...
In the research linked below, scientists describe a potentially beneficial point of interference in a tau-related mechanism of neurodegeneration: targeted sabotage of this mechanism can restore lost cognitive function and otherwise turn back some of the effects of a tauopathy, at least in the engineered mouse lineages used. Show More Summary
There is some evidence for the deposition of misfolded proteins into solid structures known as amyloid to contribute to the development of arthritis. Amyloid is better known for its role in Alzheimer's disease, but there are a number...Show More Summary
SIWA Therapeutics is one of a number of companies that have been around for some years, working away at the problem of senescent cells and their contribution to age-related disease at a slow pace. It is probably the case that some of...Show More Summary
Researchers have confirmed that mutation-caused dysfunction in a process cells use to transport molecules within the cell plays a previously suspected but underappreciated role in promoting the heritable form of Alzheimer's disease, but also one that might be remedied with existing therapeutic enzyme inhibitors.