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Best treatment option written in cancer's genetic script

An international collaboration has shown proof-of-concept that truly personalized therapy will be possible in the future for people with cancer. Details of how a knowledge bank could be used to find the best treatment option for people with acute myeloid leukemia are published in a new report.

Potentially reversible changes in gene control 'prime' pancreatic cancer cells to spread

(Johns Hopkins Medicine) A multicenter team of researchers reports that a full genomic analysis of tumor samples from a small number of people who died of pancreatic cancer suggests that chemical changes to DNA that do not affect the DNA sequence itself yet control how it operates confer survival advantages on subsets of pancreatic cancer cells.

Sunbed users get melanoma at a younger age

Melanoma is the most dangerous type of skin cancer with the strongest increase in incidence in the last decade, and the incidence rates have never been as high. The World Health Organization based International Agency for Research on...Show More Summary

Markers for prostate cancer death can identify men in need of more aggressive treatment

A prostate specific antigen (PSA) nadir greater than 0.5 ng/mL following radiation and androgen deprivation therapy appears to identify men prior to PSA failure who are at high-risk for dying early as a result of treatment failure for their prostate cancer, research shows.

New research holds promise for personalized lung cancer treatments

New research has uncovered distinct types of tumors within small cell lung cancer that look and act differently from one another. Scientists also identified a targeted drug combination that worked well with one specific tumor type. The study findings suggest small cell lung cancer should not be treated as a uniform disease.

Removable airway stent could revolutionize surgery

A knitted rag sock inspired this professor and MD to develop a stent that can easily be removed after it has done its job. 

American Cancer Society honors exemplary cancer caregivers with Lane W. Adams Quality of Life Award

(American Cancer Society) Six outstanding individuals have been honored with the American Cancer Society Lane W. Adams Quality of Life Award, a prestigious national honor for their leadership in serving the complex needs of cancer patients and their families.

New study shows promise for repurposing anti-malarial drug for cancer treatment

Chloroquine – a drug currently used to treat malaria – may be useful in treating patients with metastatic cancers, a new study suggests.

Reducing the radioresistance of cancer

Some cancer cells are protected from radiation therapy through an interaction of interleukin-6 with the Nrf2-antioxidant pathway, researchers have found. The discovery is believed to improve methods of increasing cancer's radiosensitivity.

Reducing the radioresistance of cancer

(Kumamoto University) Researchers from Kumamoto University in Japan have discovered that some cancer cells are protected from radiation therapy through an interaction of interleukin-6 with the Nrf2-antioxidant pathway. The discovery is believed to improve methods of increasing cancer's radiosensitivity.

How well do we understand the relation between incorrect chromosome number, cancer?

Researchers report surprising results of experiments intended to explore the consequences of having too many or too few chromosomes, a phenomenon that biologists call aneuploidy. They were surprised to find that having one extra chromosome actually supresses cancer, contrary to long-held belief.

Master regulator of cellular aging discovered

Scientists have discovered a protein that fine-tunes the cellular clock involved in aging.

Advanced metastatic midgut neuroendocrine tumors: New drug in development shows improved progression-free survival for patients

A new therapy in development for the treatment of midgut neuroendocrine tumors, a rare type of cancer that occurs in the small intestine and colon, shows improved progression-free survival and response rates for patients with advanced disease.

Seeing vape pen in use boosts desire to smoke among young adults

(University of Chicago Medical Center) The newer e-cigarette vape pens (AKA vaporizers) may not look like cigarettes, but they stimulate the urge to smoke as powerfully as watching someone smoke a traditional tobacco cigarette.

Huntsman Cancer Institute research holds promise for personalized lung cancer treatments

(University of Utah Health Sciences) New research from scientists at Huntsman Cancer Institute (HCI) at the University of Utah uncovered distinct types of tumors within small cell lung cancer that look and act differently from one another. Show More Summary

Columbia, NewYork-Presbyterian and non-profit Life Raft Group form cancer partnership

(Columbia University Medical Center) Collaboration will investigate the efficacy of a system biology approach to identifying treatment options for patients with advanced gastrointestinal stromal tumors.

Cost, technology issues are barriers to real-time cancer patient symptom reporting

In a perspective article, a researcher addresses the need for – and the barriers preventing – electronic reporting of patients’ symptoms between visits.

Researchers develop novel treatment to prevent graft-versus-host-disease

Graft-versus-host-disease (GVHD) is the leading cause of non-relapse associated death in patients who receive stem cell transplants. In a new study, researchers show that a novel treatment can effectively inhibit the development of GVHD in mice and maintain the infection- and tumor-fighting capabilities of the immune system.

Cost, technology issues are barriers to real-time cancer patient symptom reporting

(UNC Lineberger Comprehensive Cancer Center) In a perspective published in the New England Journal of Medicine, UNC Lineberger Comprehensive Cancer Center researcher Ethan Basch, M.D., M.Sc., addressed the need for -- and the barriers preventing -- electronic reporting of patients' symptoms between visits.

Moffitt researchers develop novel treatment to prevent graft-versus-host-disease

(H. Lee Moffitt Cancer Center & Research Institute) Graft-versus-host-disease (GVHD) is the leading cause of non-relapse associated death in patients who receive stem cell transplants. In a new study published as the cover story in Science...Show More Summary

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