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Scientists discover complex axis of immune suppression exploited by cancers

A new mechanism by which cancer cells evade destruction by the immune system has been discovered by a team of researchers. Their paper describes how immune cells known as group 2 innate lymphoid cells (ILC2s) are recruited by leukemic cells to suppress an essential anticancer immune response.

Red cosmetic powder used in Hindu ceremonies contain unsafe lead levels

(Rutgers University) Sindoor -- a cosmetic powder sold in the United States and used during Hindu religious and cultural ceremonies -- has unsafe levels of lead, according to a Rutgers University study. Researchers from the School of Public Health say at a minimum there is a need to monitor sindoor lead levels and make the public aware of the potential hazards.

Brain powered: Increased physical activity among breast cancer survivors boosts cognition

(University of California - San Diego) It is estimated that up to 75 percent of breast cancer survivors experience problems with cognitive difficulties following treatments, perhaps lasting years. Currently, few science-based options are available to help. Show More Summary

PharmaMar starts clinical studies with a new compound -PM14- in patients with solid tumors

(Pharmamar) With the motivation of finding a solution to the unmet needs of patients with different types of cancer, PharmaMar (MSE:PHM) announces the start of a Phase I clinical study with PM14, a new antitumor compound resulting from the company┬┤s internal investigation program for the treatment of patients with advanced solid tumors.

Treatment-resistant melanoma may be vulnerable to a drug holiday, study finds

A new study has uncovered the mechanisms by which treatment-resistant melanoma become vulnerable to cessation of a class of drugs called MAP kinase (MAPK)-targeted inhibitors. By identifying these mechanisms, the scientists discovered...Show More Summary

'Language of stem cells' discovered

Stem cells control the cells around them, inducing them to perform specific functions. This phenomenon of the "language of stem cells", which has now been discovered for the very first time, report investigators.

New lung cell type discovered

(Boston University School of Medicine) A recent study has identified a new lung cell type that is implicated in the body's innate immune defense against the bacteria Streptococcus pneumoniae -- one of the leading causes of pneumonia worldwide.

How patients are likely to respond to DNA drugs

Research could lead to improvements in treating patients with diseases caused by mutations in genes, such as cancer, cystic fibrosis and potentially up to 6,000 other inherited conditions.

MicroRNA helps cancer evade immune system

Researchers have discovered how oxygen-deprived tumors survive body's immune response, explains a new report.

How bacteria hinder chemotherapy

Scientists have found bacteria in pancreatic tumors that metabolize a common drug, explains a new report.

Altitude training for cancer-fighting cells

Oxygen starvation could toughen up immune T cells for cancer immunotherapy, reports a team of investigators.

ASTRO awards early-career research grants to physician-scientists

(American Society for Radiation Oncology) The American Society for Radiation Oncology (ASTRO) is awarding $275,000 in research awards to four early-career scientists as part of the Society's efforts to retain and foster the intellectual research talent currently entering the field of radiation oncology.

Springer Healthcare's Medicine Matters expands to include oncology and rheumatology resources

(Springer) Springer Healthcare has launched two new websites specializing in oncology and rheumatology to complement their flagship medical education platform, Medicine Matters diabetes. The three therapy-specific medical education platforms now form a family of products to support healthcare professionals around the world. Show More Summary

Sugary secrets of a cancer-related protein

The proteins in human cells are extensively decorated with different types of sugars, a phenomenon called glycosylation. These modifications greatly increase the diversity of protein structure and function, affecting how proteins fold, how they behave, and where they go in cells. Show More Summary

Low-level radiation exposure less harmful to health than other modern lifestyle risks

Low-level radiation exposure poses less of a health risk than other lifestyle threats, such as smoking, obesity and air pollution, according to new research. Human populations have always been exposed to ionizing radiation, and more so in modern life. Show More Summary

New inhibitor brings new hope for aggressive triple receptor-negative breast cancer

Researchers found a possible new treatment for aggressive triple receptor-negative breast cancer.

Chimera viruses can help the fight against lymphomas

Researchers have created a chimera virus that allows the study of molecules to treat cancers caused by human herpes virus infection in mice models of disease.

Thirdhand smoke exposure effects on liver and brain found to worsen over time

(University of California - Riverside) Thirdhand-smoke (THS) results when exhaled smoke and smoke emanating from the tip of burning cigarettes gets on surfaces such as clothing, hair, homes, and cars. Using a mouse model, researchers...Show More Summary

New study shows that genomic profiling can help improve treatment of brain tumors in children

(Wiley) The largest genomic profiling study ever conducted into a type of brain tumor known as glioma in children has identified genetic alterations in 96% of cases. As reported in The Oncologist, this genetic information could helpShow More Summary

Link between breast cancer and obesity influenced by type of obesity, says Chinese study

(Wiley) Obese women with large bellies may be at risk of developing a different subtype of breast cancer than those with widespread fat accumulation, according to a new study published in The Oncologist. This suggests that the link between breast cancer and obesity may be more complex than previously thought.

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