All Blogs / Health / Diseases & Conditions / Cancer / New


Long-sought mechanism of metastasis is discovered in pancreatic cancer

An important discovery establishes a cause of metastasis in pancreatic cancer. Using organoids grown from patient tissues and transplanted in mouse models of the illness, the team pinpoints an epigenetic re-programming of gene enhancers...Show More Summary

Genome-wide cancer 'dependency map' now revealed

In one of the largest efforts to build a comprehensive catalog of genetic vulnerabilities in cancer, researchers have identified more than 760 genes upon which cancer cells from multiple types are strongly dependent for their growth and survival. Show More Summary

Errors made by 'DNA spellchecker' revealed as important cause of cancer

Important processes that create mutations that cause cancer have been identified by researchers studying the genomes of more than 1,000 tumors. Many mutations in human cancers are caused by mistakes made by a repair mechanism or 'DNA spellchecker' rather than the actual damage to DNA caused by the environment. Show More Summary

Case Western Reserve University School of Medicine faculty receives funding

(Case Western Reserve University) Alex Huang has been awarded a $150,000 St. Baldrick's Foundation Innovation Award.

Cancer-death button gets jammed by gut bacterium

A type of bacterium is associated with the recurrence of colorectal cancer and poor outcomes, research show. Scientists found that Fusobacterium nucleatum in the gut can stop chemotherapy from causing a type of cancer cell death called apoptosis.

Researchers release first draft of a genome-wide cancer 'dependency map'

(Broad Institute of MIT and Harvard) In one of the largest efforts to build a comprehensive catalog of genetic vulnerabilities in cancer, researchers have identified more than 760 genes upon which cancer cells from multiple types are strongly dependent for their growth and survival. Show More Summary

Cancer-death button gets jammed by gut bacterium

(Michigan Medicine - University of Michigan) Researchers at Michigan Medicine and in China showed that a type of bacterium is associated with the recurrence of colorectal cancer and poor outcomes. They found that Fusobacterium nucleatum in the gut can stop chemotherapy from causing a type of cancer cell death called apoptosis.

Long-sought mechanism of metastasis is discovered in pancreatic cancer

(Cold Spring Harbor Laboratory) An important discovery at CSHL establishes a cause of metastasis in pancreatic cancer. Using organoids grown from patient tissues and transplanted in mouse models of the illness, the team pinpoints anShow More Summary

Errors made by 'DNA spellchecker' revealed as important cause of cancer

(Center for Genomic Regulation) CRG scientists identify important processes that create mutations that cause cancer by studying the genomes of more than 1,000 tumors. Many mutations in human cancers are caused by mistakes made by a repair mechanism or 'DNA spellchecker' rather than the actual damage to DNA caused by the environment. Show More Summary

Stem cell therapy attacks cancer by targeting unique tissue stiffness

A stem cell-based method can selectively target and kill cancerous tissue while preventing some of the toxic side effects of chemotherapy by treating the disease in a more localized way, report investigators.

E-cigarette use may encourage experimentation with tobacco, study finds

(University of Stirling) Young people who have tried an e-cigarette may be more likely to go on to smoke cigarettes compared with those who have not, a study led by University of Stirling researchers has suggested.

Research evaluates impact of surgical modality on breast-specific sensuality

Does the type of surgery used to treat breast cancer impact a woman's sensuality and sexual function in survivorship? New research analyzed the association of surgical modality with sexual function and found that breast-specific sensuality and appearance satisfaction are better with lumpectomy and may correlate with improved sexual function post-operatively.

Study uncovers potential 'silver bullet' for preventing and treating colon cancer

In preclinical experiments, researchers have uncovered a new way in which colon cancer develops, as well as a potential 'silver bullet' for preventing and treating it. The findings may extend to ovarian, breast, lung, prostate and potentially other cancers that depend on the same mechanism for growth.

Americans are quitting smoking in higher numbers; study suggests e-cigarettes help

(University of California - San Diego) University of California San Diego School of Medicine and Moores Cancer Center researchers performed a population-level analysis of national surveys conducted from 2001 to 2015 and found that in the United States the smoking cessation rate increased for the first time in 15 years. Show More Summary

Gene mutations in smoking-related cancers identified

African-Americans typically have worse outcomes from smoking-related cancers than Caucasians, but the reasons for this remain elusive. However, scientists have now taken a big step toward solving this puzzle.

UCI stem cell therapy attacks cancer by targeting unique tissue stiffness

(University of California - Irvine) A stem cell-based method created by University of California, Irvine scientists can selectively target and kill cancerous tissue while preventing some of the toxic side effects of chemotherapy by treating the disease in a more localized way.

How body may detect early signs of cancer

Fresh insights into how cells detect damage to their DNA -- a hallmark of cancer -- could help explain how the body keeps disease in check. Scientists have discovered how damage to the cell's genetic material can trigger inflammation, setting in motion processes to remove damaged cells and keep tissues healthy.

Anti-cancer chemotherapeutic agent inhibits glioblastoma growth and radiation resistance

A unique and previously unidentified molecular mechanism has been discovered that maintains glioma stem cells, report investigators. They have tested it as a potential therapeutic target in glioblastoma, using a novel small molecule inhibitor they designed and synthesized

Biomarkers for identifying tumor aggressiveness

Future early-stage colon cancer patients could benefit from specific genetic tests that forecast their prognosis and help them make the right decision regarding chemotherapy. Two of the biomarkers are the MACC1 gene, high levels of which...Show More Summary

Penn Center for Precision Medicine awards $565,000 in second Accelerator grants

(University of Pennsylvania School of Medicine) The Penn Center for Precision Medicine Accelerator Fund awarded eight research teams from Penn Medicine in their second round of funding for the implementation of personalized medicine projects across a range of clinical specialties,

Copyright © 2015 Regator, LLC