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New report one of the most comprehensive studies on health effects of e-cigarettes

(National Academies of Sciences, Engineering, and Medicine) A new congressionally mandated report from the National Academies of Sciences, Engineering, and Medicine takes a comprehensive look at evidence on the human health effects of e-cigarettes. Show More Summary

A weak heart due to metabolic change

(German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ)) The heart derives its energy primarily from fatty acids. However, if a metabolic shift to other energy sources takes place, this can result in congestive heartShow More Summary

Developing the VTX-1 liquid biopsy system: Fast and label-free enrichment of circulating tumor cells

A new platform could change the way cancer is diagnosed and treated by automating the isolation of circulating tumor cells (CTCs) directly from cancer patient blood.

How breast cancer survivors can increase their reduced life expectancy

(University of Southern California) A USC study suggests regular exercise could add to the life expectancy of breast cancer survivors because it lowers their heightened risk of cardiovascular disease, Type 2 diabetes and possibly breast cancer recurrence. Show More Summary

TSRI researchers identify gene responsible for mesenchymal stem cells' stem-ness'

(Scripps Research Institute) Researchers at The Scripps Research Institute recently published a study in the journal Cell Death and Differentiation identifying factors crucial to mesenchymal stem cell differentiation, providing insight into how these cells should be studied for clinical purposes.

Boosting cancer therapy with artificial molecules

Researchers have created artificial molecules that can help the immune system to recognize and attack cancer tumors.

Researchers identify a protein that keeps metastatic breast cancer cells dormant

(Institute for Research in Biomedicine (IRB Barcelona)) A study headed by ICREA researcher Roger Gomis at the Institute for Research in Biomedicine (IRB Barcelona) has identified the genes involved in the latent asymptomatic state of breast cancer metastases. Show More Summary

Virus shown to be likely cause of mystery polio-like illness

A major review has identified strong evidence that a virus called Enterovirus D68 is the cause of a mystery polio-like illness that has paralyzed children in the US, Canada and Europe.

Swallowable test to detect pre-cancerous Barrett's esophagus

Investigators have developed a simple, swallowable test for early detection of Barrett's esophagus that offers promise for preventing deaths from esophageal adenocarcinoma.

Bioengineered soft microfibers improve T-cell production

Researchers have developed a new method for improving T cell manufacture by focusing on the materials involved in this process. Their study uses a polymer mesh to activate the T cells, a critical step for their production. This approach simplifies processing compared to systems in use today. Show More Summary

Hedgehog signaling proteins keep cancer stem cells alive

Scientists have discovered that the survival of cancer stem cells is dependent on the 'Hedgehog signaling pathway'. Targeting this pathway had previously shown no effect on the growth of colorectal cancer. Now, scientists have demonstrated that using different drugs to target a specific aspect of the pathway may yield better treatment outcomes for patients.

New drug combination helps kickstart the immune system to fight back against cancer

Scientists have found a way to boost the immune system to help it fight back against cancer. The breakthrough involves the first ever use of a combination of chemotherapy and a drug being trialed as a treatment for neonatal jaundice, that together help kick start the body's natural defenses.

Factor that doubles the risk of death from breast cancer identified

Researchers have discovered that the risk of death from breast cancer is twice as high for patients with high heterogeneity of the estrogen receptor within the same tumor as compared to patients with low heterogeneity. The study shows that the higher risk of death is independent of other known tumor markers and also holds true for Luminal A breast cancer.

Creation of synthetic horsepox virus could lead to more effective smallpox vaccine

Researchers created a new synthetic virus that could lead to the development of a more effective vaccine against smallpox. The discovery demonstrates how techniques based on the use of synthetic DNA can be used to advance public health measures.

Can mice really mirror humans when it comes to cancer?

A new study is helping to answer a pressing question among scientists of just how close mice are to people when it comes to researching cancer. The findings reveal how mice can actually mimic human breast cancer tissue and its genes, even more so than previously thought, as well as other cancers including lung, oral and esophagus.

New method to stop cells dividing could help fight cancer

Researchers have used a new strategy to shut down specific enzymes to stop cells from dividing. The method can be used as a strategy to fight cancer.

MIT Portugal is developing a Compression sleeve for breast cancer patients

(MIT Portugal Program) The project developed by the MIT Portugal PhD Student at the University of Minho Carlos Gonçalves, was considered the most innovative of the 9 projects incubated during 10 weeks by Startup Nano, a pioneer incubation...Show More Summary

New gene variant linked to deadly prostate cancer

Researchers have confirmed for the first time a mechanistic link between the gene HSD17B4 and deadly, treatment-resistant prostate cancer. The research shows that men who lack a certain subtype of the gene may be more susceptible to aggressive prostate cancer that does not respond to treatment.

CancerSEEK: Generalized screening for multiple cancer types

(American Association for the Advancement of Science) Researchers have developed a noninvasive blood test based on combined analysis of DNA and proteins that may allow earlier detection of eight common cancer types. In more than 1,000 patients, their method, dubbed CancerSEEK, detected cancer with a sensitivity of 69 to 98 percent (depending on cancer type).

Scientists identify potential target genes to halt progression of thyroid cancer

(Fundação de Amparo à Pesquisa do Estado de São Paulo) Research shows that expression of 52 microRNAs falls as the disease becomes more aggressive. Restoring levels of these molecules in the tumor could be a novel therapeutic strate...

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