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AMP to recognize Eric Lander with 2016 Award for Excellence in Molecular Diagnostics

(Association for Molecular Pathology) Eric Lander, Ph.D., has earned this year's Association for Molecular Pathology (AMP) Award for Excellence in Molecular Diagnostics for his countless contributions to the field. The award will be presented at the AMP 2016 Annual Meeting. Show More Summary

Physical activity may offset some of alcohol's lethal harms

(University of Sydney) An international research collaboration, led by University of Sydney, has found that exercising at even basic recommended weekly physical activity levels (at least 150 minutes of moderate-intensity activity) may offset some of the harmful effects of drinking alcohol. Show More Summary

Cord blood transplant associated with high survival rate in high-risk leukemia patients

(Fred Hutchinson Cancer Research Center) Umbilical cord blood transplants may have advantages beyond offering an alternative stem cell source for leukemia patients without a traditional donor match, according to a study published today in The New England Journal of Medicine.

Patients with advanced lymphoma in remission after T-cell therapy

(Fred Hutchinson Cancer Research Center) In a paper published today in Science Translational Medicine, researchers from Fred Hutchinson Cancer Research Center shared data from an early-phase study of patients with advanced non-Hodgkin lymphoma (NHL) who received JCAR014, a Chimeric Antigen Receptor (CAR) T cell treatment, and chemotherapy. Show More Summary

10 Cancer Moonshot Blue Ribbon Panel recommendations embraced by NCI

(University of California - San Diego) When 28 distinguished individuals convened earlier this year to help shape the scientific mission at the National Cancer Institute (NCI) of Vice President Joe Biden's National Cancer Moonshot Initiative, they were given five months to draft guidelines to accelerate cancer research, prevention and care. Show More Summary

RIT and Rochester Regional Health collaborate to improve breast cancer screening

(Rochester Institute of Technology) Researchers at Rochester Institute of Technology and physicians at Rochester Regional Health are advancing thermal imaging techniques as a potentially safer and less invasive diagnostic tool for the detection of early-stage breast cancer. A National Science Foundation grant of $99,620 is supporting the two-year project.

Scientists identify genes that disrupt response to breast cancer treatment

(University of Illinois at Urbana-Champaign) In breakthrough research on breast cancer, a team at the University of Illinois discovered that higher levels of the nuclear transport gene XPO1 indicate when a patient is likely to be resistant to the popular drug tamoxifen. The team is led by food science and human nutrition professor Zeynep Madak-Erdogan.

LSU Health dentistry grant to help improve oral cancer survival

(Louisiana State University Health Sciences Center) Dr. Kitrina Cordell, Associate Professor and Head of the Department of Diagnostic Sciences at LSU Health New Orleans School of Dentistry, has been awarded a grant by the Academy of General Dentistry to develop a school-wide program to teach patients about self oral cancer screening. Show More Summary

Aberrant epigenetic regulation behind the intestinal symptoms in celiac disease

(Academy of Finland) Researchers at the University of Tampere discovered a regulation mechanism governing the intestinal homeostasis. Disturbances in this mechanism are implicated in celiac disease and possibly also in colorectal cancer.

CAR-T cell therapy makes strides in clinic free

(American Association for the Advancement of Science) In a phase 1 clinical study of 32 participants with advanced B cell non-Hodgkin lymphoma, immunotherapy with defined subsets of T cells, rather than whole T cell populations, showed strong antitumor activity.

Combination therapy shows promise for chronic myeloid leukemia

(University of Texas M. D. Anderson Cancer Center) A study in mice combining two inhibitor drugs for treatment of chronic myeloid leukemia has revealed potential for not only stopping the disease completely, but also significantly lowering the cost for treatment.

Computer simulation reveals p53 weak spots and opens new avenues against cancer

(Publicase Comunicação Científica) Using microsecond timescale molecular dynamics simulations, a new study published in Scientific Reports reveals p53 weak spots and sheds light on the protein instability, which is linked to its tendency to aggregate and form amyloid structures.

ESMO rewards outstanding oncologists

(European Society for Medical Oncology) The European Society for Medical Oncology (ESMO), the leading professional organization for medical oncology, has revealed the four outstanding recipients of its distinguished awards.

ESMO Women for Oncology awards Sumitra Thongprasert

(European Society for Medical Oncology) Professor Sumitra Thongprasert has been awarded the second ESMO Women for Oncology award, honoring her position as a role model for women in the profession and for her distinguished career.

Research shows it may be time to abandon dreaded digital rectal exam

(Wake Forest Baptist Medical Center) The dreaded finger exam to check for prostate cancer used to be a mainstay of check-ups for older men. With its value now in question, some doctors share the risks and benefits with their patients and let them decide. Show More Summary

Tumor microenvironment acts as a mechanism of resistance to chemotherapy

(IDIBELL-Bellvitge Biomedical Research Institute) Researchers from IDIBELL have published a new Oncotarget paper that highlights the importance of tumor environment as a source of resistance to treatment in colorectal cancer, the fourth most common cancer and the leading cause of cancer death worldwide.

CNIO scientists have discovered a specific molecular biomarker for malignant melanoma

(Centro Nacional de Investigaciones Oncológicas (CNIO)) Melanoma is one of the types of cancer that poses the greatest challenge to researchers because it manifests itself in many ways, it contains a large number of mutations and displays high metastatic capacity. Show More Summary

Deaths from ovarian cancer decline worldwide due to oral contraceptive use

(European Society for Medical Oncology) Deaths from ovarian cancer fell worldwide between 2002 and 2012 and are predicted to continue to decline in the USA, European Union and, though to a smaller degree, in Japan by 2020, according to new research published in the leading cancer journal Annals of Oncology. Show More Summary

Obesity linked to improved survival in kidney

(Dana-Farber Cancer Institute) Obesity almost always increases cancer risk and worsens outcomes, but researchers led by scientists at Dana-Farber Cancer Institute report that overweight patients with advanced kidney cancer had significantly longer survival than those who were normal or underweight.

New HIF-2 kidney cancer therapy more effective than current treatment, study shows

(UT Southwestern Medical Center) A new class of drugs called HIF-2 inhibitors is more effective and better tolerated than the standard of care drug sunitinib in treating kidney cancer, researchers with the Kidney Cancer Program at Harold C. Simmons Comprehensive Cancer Center have found.

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