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Molecules in the body more visible in new detection system, say scientists

A technique that will enhance the performance of magnetic resonance imaging (MRI) in identifying disease has now been developed by researchers.

Previous exposure to flaviviruses increases effects of Zika

Prior infection with dengue or West Nile virus can enhance the effects of Zika infection, a new study using human samples tested in mice finds.

Novel vulnerabilities in dengue virus discovered

Hidden vulnerabilities on the surface of the dengue virus have been found by researchers. This discovery offers exciting possibilities for development of drugs to target these weak spots for treatment of dengue and related viruses such as Zika.

Kidney transplants: White blood cells control virus replication

Certain white blood cells play an important role in bringing a harmful virus under control after kidney transplantations. These research results could contribute to improving control of immunosuppression, avoiding transplant rejection and developing relevant vaccines.

Larger doses of vitamin C may lead to a greater reduction in common cold duration

The relationship between vitamin C dosage and its effects on the duration of the common cold symptoms may extend to 6-8 grams per day.

How Zika virus rewires and repurposes invaded cells

New research reveals a high-resolution view of the Zika viral life cycle within infected cells and shows dramatic changes in the cell's architecture throughout the infection process. This novel perspective may lead to the development of new vaccines and treatments.

Addressing the threat of Zika virus to US blood supply

Certain screening methods that detect the genetic material of Zika virus can be used to ensure that donated blood supplies remain free of the virus, investigators have shown.

Long-term antibiotic use in early to mid-life linked to cancer-inducing polyps

(BMJ) Long-term antibiotic use in early to mid-life may be linked to a heightened risk of abnormal growths in the colon and rectum -- known as polyps or colorectal adenomas -- which precede the development of most cases of bowel cancer, reveals research published online in the journal Gut.

Developing adoptive T cell therapy for ovarian cancer

(Fred Hutchinson Cancer Research Center) Dr. Kristin Anderson from Fred Hutch will describe preclinical research on T-cell therapy showing how engineered T cells are able to kill both human and mouse ovarian cancer cells in the lab and significantly extend survival in a mouse model.

Supercomputers reveal how cell membranes keep cancer-causing proteins turned off

Two biophysicists have used supercomputers to show how cell membranes control the shape, and consequently the function, of a major cancer-causing protein.

Method identified to boost detection of highly cancerous stem cells

A subpopulation of highly cancerous stem cells has been discovered in a brain cancer cell line. The cells are not identified by standard tumor cell fluorescence detection methods. By investigating the pathways involved in breaking down...Show More Summary

Single-cell RNA sequencing reveals detailed composition of two major types of brain tumor

Detailed analysis of two brain tumor subtypes has revealed that they may originate from the same type of neural progenitor cells and be distinguished by gene mutation patterns and by the composition of their microenvironments.

Ultrasound and microbubbles flag malignant cancer in humans, Stanford-led study finds

(Stanford University Medical Center) A team led by researchers from the Stanford University School of Medicine has demonstrated a way to diagnose cancer without resorting to surgery, raising the possibility of far fewer biopsies.

Drugs widely used in cancer therapy increase toxicity of chemotherapy in mice

(University of Southern California) A short-term fast appears to counteract increases in blood sugar caused by common cancer drugs and protect healthy cells in mice from becoming too vulnerable to chemotherapy, according to new research from the University of Southern California.

New gene discovered that is driving drug resistance

A gene that is ‘revving the engine of cancer’ against the world’s most common breast cancer drug has been discovered by scientists.

Supercomputers reveal how cell membranes keep cancer-causing proteins turned off

(Case Western Reserve University) Two biophysicists from Case Western Reserve University School of Medicine have used supercomputers to show how cell membranes control the shape, and consequently the function, of a major cancer-causing protein.

PharmaMar presents new data on the treatment of MM and OC at the AACR Congress

(Pharmamar) PharmaMar (PHM:MSE) has presented new data on the mechanism of action of plitidepsin and lurbinectedin during the Annual Congress of the American Association of Cancer Research (AACR), which is being held in Washington D.C. (United States) on April 1-5.

Study finds more childhood cancer survivors would likely benefit from genetic screening

(St. Jude Children's Research Hospital) St. Jude Children's Research Hospital has completed the first whole genome sequencing of cancer survivors and found that 12 percent of childhood cancer survivors carry mutations linked to an increased risk of cancer.

Blood vessels and the immune system talk to each other

Tumor blood vessels and the immune system influence each other's functions, and propose that considering these bilateral effects in cancer therapy might improve outcomes, researchers have found.

Anti-cancer drug gets a boost when combined with antirheumatic

Combining an anticancer drug with an antirheumatic produces improved effects against tumors, scientists have discovered. The discovery opens a new path for drug-drug synergy.

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