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The complex acid-base problem – my interpretation

Patient had been feeling poorly for a few days with progressive dyspnea and weakness. Denied fever, chills or sweats. No past medical history – had avoided physicians for more than 40 years. 141 96 36 105 2.8 20 1.5 On 2 liters nasal oxygen pH 7.45 pCO2 29 pO2 55 HCO3 20 My interpretation 1. The […]

Being an attending means being a teacher. Take that job seriously.

“Sometimes a simple, almost insignificant gesture on the part of a teacher can have a profound formative effect on the life of a student.” – Paulo Freire Think back to a moment when a teacher or “authority” figure gave you a compliment. We all have them, from kindergarten to high school to college and sometimes […]

The sad story of how “never events” prevent obese patients from getting new hips

Daytime TV advertising is dominated by two players. Pharmaceutical companies with direct to consumer pitches and the so-called “toxic tort.” How confusing it must be to the average person to see a new drug pushed by one commercial, to be immediately followed by another commercial from a lawyer trying to sue for the known side […]

You have access to a doctor 24 hours per day. When should you call one?

Patients are entitled to receive medical advice 24 hours a day. If you call your doctor at 3 a.m., you will reach a physician who will advise you. Of course, it may not be your own personal physician as this individual cannot be expected to be available 365 days a year until he retires. Physicians […]

News Roundup, July 2015: CVS Health, Allergan, Specialty Pharmacies, and Amy Schumer

The hot and hazy days of summer are here. Cool off with my refreshing selection of articles that cut through the steamy haze. In this issue: A handy primer on CVS Health’s history and strategy Allergan’s CEO explains how channel consolidation...Show More Summary

Advertising The Future Health Care Marketplace

By MITCH ROTHSCHILD Looking out the train window at a NJ Transit Coastline stop, I saw the future of shopping in health care. On the platform were side-by-side advertisements for health plans. Typically the domain of Broadway shows, mobile carriers and whiskey makers, seeing not one, but two insurance companies vie for mind space among

At 50, Medicare and Medicaid Face the Challenge of a New Generation of Super-Expensive Drugs

By STEVEN FINDLAY Happy birthday Medicare and Medicaid!   Fifty years old today.   Middle age.  Congratulations.  You’ve survived a lot—and 76 million baby boomers and 60 million low-income Americans are mighty glad you’re still around, covering one in three Americans, with solvency until 2030 at last accounting. Unfortunately, the challenges are not going to let up. 

New Optical Technology Adds Zoom, Auto Focus to Endoscopes

Modern clinical endoscopes are still limited in their ability to visualize difficult to reach areas. Some endoscopes have zooming and auto-focus features, but the extra necessary components are making them bulkier. Now researchers at...Show More Summary

ReShape Dual Balloon Non-Surgical Alternative to Stomach Stapling FDA Approved

ReShape Medical‘s dual-balloon weight loss system has been approved by the FDA as an option for patients who have contraindication for or looking to avoid traditional bariatric surgery. The ReShape procedure doesn’t involve any surgery and is completely reversible. Show More Summary

The Move is Nigh

The day for the big Pipeline move is almost at hand! Friday's posts here will be the last on the Corante site, and the new one at Science Translational Medicine will go live on Monday morning. I'll post the new URL shortly. I wantedShow More Summary

Another Alzheimer's IPO

I've been saying a lot of unkind things about Axovant, the insta-company that's taking a discarded GSK Alzheimer's candidate and running with it. But thanks to Adam Feuerstein, I have another company to roll my eyes about. They have a completely different Alzheimer's plan - they've taken a discarded Pfizer candidate and are running with it. Show More Summary

Entresto, Blockbuster, or Just Over Hyped? - Whatever, It Will Cost $4500 a Year

The newest drug for congestive heart failure, Entresto, a fixed combination of valsartan and sacubitril, has just hit the market at an elevated price. Like other drugs recently introduced as blockbusters, the high price does not seem clearly justified by clinical evidence about the drug's benefits and harms. Show More Summary

Livongo Health Uses Big Data to Advance Diabetes Care

Liaison Technologies, an industry-recognized leader in cloud-based integration and data management offerings, today announced that its ALLOY Health™ platform has been chosen by Livongo Health™ to speed adoption of Livongo’s chronic condition health management program. Show More Summary

Kareo Raises $55M to Expand Small Physician Practice EHR

  Kareo, a cloud-based EHR provider for independent medical practices has closed $55.4 million in additional funding led by Montreux Equity Partners with participation from Silver Lake Partners and all of Kareo’s existing investors.Show More Summary

Former Teva Employee Blames Firing on Helping Feds With Bribery Probe

A former Teva employee claims she was fired for helping U.S. officials with their investigation into FCPA violations.

Pharmalot.. Pharmalittle.. Good Morning: We’re Catching up on Glaxo, MannKind and Lots More!!

Good morning, everyone, and how are you today? The heat continues to rise higher here on the Pharmalot campus, where we are hoping for storm clouds to wash away the humidity that has so far characterized the past few days. One can dream,...Show More Summary

KLAS Announces Top-Performing Vendors in 2015 Midterm Performance Review: Software & Services Report

Thousands of healthcare providers at physician offices, clinics, hospitals and IDNs in Northern America weighed in to provide feedback about healthcare technology software vendors in 93 market segments. The KLAS 2015 Midterm Performance...Show More Summary

The Long March Toward Medicare

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Health Trackers Are Changing The Experience of Pregnancy

The revolution of health tracking is getting closer to pregnancy with every new device or gadget that is designed to help expectant mothers measure health parameters about themselves or their babies. With my wife, we are looking forward to having kids as soon as possible and I won’t be able to resist the temptation to […]

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