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Top stories in health and medicine, August 26, 2014

From MedPage Today: Adrenaline: The Best and Worst of Drugs. Despite it being the first-line adrenergic drug for patients with cardiac arrest, few studies in humans have assessed epinephrine’s effectiveness. Increase E-Cig Regulation, Says AHA. Show More Summary

The Wisdom Of Providing Consumers Access To Test Results Needs Careful Consideration.

The drivers of the PCEHR Program are keen to have results included in the PCEHR. There have been some recent articles that bear on this issue.First we have:Study: Many patients don’t understand electronic lab resultsAuthor Name Jennifer...Show More Summary

Submission To The PCEHR Review - Sent By E-Mail Today.

PCEHR Review Consultation Submission - DG More - August 2014 IntroductionThe following submission has been prepared to offer some commentary and input to the process now underway, being facilitated by Deloitte, to ascertain stakeholder...Show More Summary

DNR/DNI: More code than status

“If a tree falls in a forest and no one is around to hear it, does it make a sound?” Chances are that many of you have duked this out with your college roommates back in the day, but how about this one? “If a doctor and a patient make an advance care plan, but […]

IP Gloves Help Prevent Spread of Infection Thanks to Clever Trick (VIDEO)

Medical gloves are a great way to help prevent the spread of infection from person to person within clinical environments, but traditional gloves are are difficult to take off without contaminating the wrists in the process. A new product...Show More Summary

When medications devalue the opportunity to listen

When I hear debate over the association between SSRIs (selective serotonin re-uptake inhibitors, a class of antidepressant medication) and suicidal behavior in children and adolescents, I am immediately brought back to a night in the early 2000s.  As the covering pediatrician I was called to the emergency room to see a young man, a patient […]

Inaugural Clinical Alarm Safety Symposium

Clinical alarm safety can be hard to achieve, and once […]

Withings Aura Sleep Assist System Now Available for Purchase

Having unveiled its Aura sleep system at CES in January of this year, Withings is now making the innovative product available for purchase. The Aura includes a sensor that’s placed under the mattress capable of continuously monitoring the person’s heart rate, breathing, and movement while sleeping. Show More Summary

Desorption Electrospray Ionization for Brain Tumor Identification

NBIB-funded researchers have developed a new and more efficient method for screening brain tumors. The method uses a technique called Desorption Electrospray Ionization Mass Spectrometry (DESI MS) to screen for 2-hydroxyglutarate (2-HG), a metabolite which is formed from a mutation in the brain tumor inducing gene IDH. Show More Summary

Small Molecules - Really, Really Small

Mentioning such a small compound as pirfenidone prompts me to put up the graphic shown below: these are the smallest commonly used drugs that I can think of. (OK, there's cocaine as a nasal anaesthetic - no, really - but that's where I draw the line at "commonly used". Show More Summary

Medtronic’s Viva CRT-P with AdaptivCRT Approved in U.S.

Medtronic‘s Viva cardiac resynchronization therapy-pacemaker (CRT-P) received FDA approval for use on appropriate patients with heart failure or atrioventricular (AV) block. The device made its debut in Europe earlier this year, featuring...Show More Summary

Surgeons can’t be responsible for every mistake

Several months ago, a post called, “Everything’s my fault: How a surgeon says I’m sorry,” appeared here on It was written by a plastic surgeon who feels that no matter goes wrong with a patient, surgeons should never blame anyone else. She gave some examples such as the lab losing a specimen, a chest x-ray that […]

Undetectable high sensitive troponin I in PE

Associated with favorable prognosis in this study, and the potential for outpatient treatment. Via Hospital Medicine Virtual Journal Club.

How listing side effects on TV ads can sell more drugs

I must not be the only person to wonder how pharmaceutical companies succeed with direct to consumer advertisements when, stuck in the middle of all their TV ads, are those long lists of side effects.  You know what I mean.  After watching a smiling and attractive person running through a field after receiving some wonder […]

Citable Garbage

Experimental and Clinical Cardiology used to be a reputable journal. Now it's a trash heap piled with crap. No, literally - the Ottawa Citizen newspaper has proof, thanks to reporter Tom Spears (who's an experienced hand at this). The...Show More Summary

InterMune Bought

It has been a bizarre ride for InterMune, its employees, and its investors. But now it ends with Roche buying them for $8.3 billion dollars, a sum that would have brought incredulous stares a few years ago. The deal makes sense for Roche, and it will provide investors a rationale for years as they buy into small biopharma companies - trying to pick the next InterMune, you know.

The uphill climb of complex care management

In an ironic analogy to the recent Occupy Wall Street movement publicizing the wealth gap between America’s elite and the general public, the health care world also has its own infamous 1%. According to the Agency for Healthcare Research and Quality’s 2012 report, the top 1% of health care seekers incurs nearly a third of […]

Roche CEO On Intermune Deal: ‘This Is A Growth Story’

Since its founding in 1998, Brisbane, Calif.-based Intermune, a startup focused on lung diseases, has exemplified the vagaries of the biotechnology industry. Its first drug, ActImmune for two rare congenital diseases, was a flop sold off to Vidara Pharmaceuticals for just $55 million. In his efforts to promote the medicine, former chief executive Scott Harkonen [...]

Mobile App Usage Surges. Will Pharma Ads Follow?

According to the 2014 U.S. Mobile App Report by Comscore, U.S. digital consumers now spend more time using mobile apps than they do  on desktop computers (see chart below). "Total U.S. digital media time spent has jumped 24 percent in...Show More Summary

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