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“Copernican” Reassessment of the Human Mitochondrial DNA Tree

The Cambridge Reference Sequence is dead, long live the RSRS! Let's hope for a smooth transition. The supplement (the paper itself is open access). Table S5 within the supplement is very interesting, as it contains age estimates for the nodes of the new mtDNA phylogeny, and places the common mtDNA ancestor of humans (represented by the new reference sequence) at ~177,000 years.
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Another look at mtDNA

Biology / Genetics : Gene Expression (3 years ago)

The new article in The American Journal of Human Genetics, A “Copernican” Reassessment of the Human Mitochondrial DNA Tree from its Root, is open access, so you should check it out. The discussion gets to the heart of the matter: Su... Read Post

Could Screening For Mitochondrial DNA Mutations Improve Prostate Cancer Diagnosis?

Health : Medical News Today (4 years ago)

A new study that found DNA mutations throughout the mitochondrial genome were linked to increased levels of prostate specific antigen (PSA) and prostate cancer itself raises the interesting suggestion that perhaps screening a man's ... Read Post

Discovery Of 'Quadruple Helix' DNA In Human Cells Opens Up Possibilities For A New Generation Of Targeted Therapies For Cancer

Health : Medical News Today (2 years ago)

In 1953, Cambridge researchers Watson and Crick published a paper describing the interweaving 'double helix' DNA structure - the chemical code for all life. Now, in the year of that scientific landmark's 60th Anniversary, Cambridge ... Read Post


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