The Cambridge Reference Sequence is dead, long live the RSRS! Let's hope for a smooth transition.
The supplement (the paper itself is open access). Table S5 within the supplement is very interesting, as it contains age estimates for the nodes of the new mtDNA phylogeny, and places the common mtDNA ancestor of humans (represented by the new reference sequence) at ~177,000 years.
A new study that found DNA mutations throughout the mitochondrial genome were linked to increased levels of prostate specific antigen (PSA) and prostate cancer itself raises the interesting suggestion that perhaps screening a man's ... Read Post
A more specific method for deleting mutant mitochondrial DNA in human cells in order to combat diseases associated with mitochondrial dysfunction is reported in a paper published this week in Nature Medicine. These results may event... Read Post