Post Profile

“Copernican” Reassessment of the Human Mitochondrial DNA Tree

The Cambridge Reference Sequence is dead, long live the RSRS! Let's hope for a smooth transition. The supplement (the paper itself is open access). Table S5 within the supplement is very interesting, as it contains age estimates for the nodes of the new mtDNA phylogeny, and places the common mtDNA ancestor of humans (represented by the new reference sequence) at ~177,000 years.
read more


Related Posts

"The worm in the fruit of the mitochondrial DNA tree"

Academics / Anthropology : John Hawks Anthropology Weblog

François Balloux (2009) has a polemic in the online access area of Heredity presenting references about mtDNA selection, and arguing that the use of this single genetic marker is no longer warranted without support from other loci. ...

Examining Mitochondrial DNA Damage With Aging in Human Tissues

Health / Aging : Fight Aging

We age in part because mitochondrial DNA accumulates mutations, probably via oxidative damage. Mitochondria exist as bacteria-like self-replicating herds within our cells, and mitochondrial function is essential to cellular processe...

Climate Shaped the Worldwide Distribution of Human Mitochondrial DNA Sequence Variation – Balloux et al: Proceedings Royal Society B

Academics / Anthropology :

This looks like a pretty interesting paper, postulating that mtDNA diversity is lower in populations residing in cooler climates – it’s free to access here, and in the meantime, here’s the abstract: There is an ongoing discussion in...

mtDNA from Late Bronze Age West Siberia (Stary Sad)

Academics / Anthropology : Dienekes' Anthropology Blog

From the paper: All of the samples studied have a different sequence of mitochondrial DNA HVR I (Table). An analysis of haplotype structure enabled its attribution to five mitochondrial DNA haplogroups: western Eurasian U2e, U5a, T ...

Another look at mtDNA

Biology / Genetics : Gene Expression

The new article in The American Journal of Human Genetics, A “Copernican” Reassessment of the Human Mitochondrial DNA Tree from its Root, is open access, so you should check it out. The discussion gets to the heart of the matter: Su...


Copyright © 2016 Regator, LLC