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“Copernican” Reassessment of the Human Mitochondrial DNA Tree

The Cambridge Reference Sequence is dead, long live the RSRS! Let's hope for a smooth transition. The supplement (the paper itself is open access). Table S5 within the supplement is very interesting, as it contains age estimates for the nodes of the new mtDNA phylogeny, and places the common mtDNA ancestor of humans (represented by the new reference sequence) at ~177,000 years.
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Could Screening For Mitochondrial DNA Mutations Improve Prostate Cancer Diagnosis?

Health : Medical News Today (3 years ago)

A new study that found DNA mutations throughout the mitochondrial genome were linked to increased levels of prostate specific antigen (PSA) and prostate cancer itself raises the interesting suggestion that perhaps screening a man's ... Read Post

Getting a TALEN-hold on mitochondrial disease

Health : Medical News Today (8 months ago)

A more specific method for deleting mutant mitochondrial DNA in human cells in order to combat diseases associated with mitochondrial dysfunction is reported in a paper published this week in Nature Medicine. These results may event... Read Post

A Midlife Crisis for the Mitochondrial Free Radical Theory of Aging

Health / Aging : Fight Aging (9 hours ago)

Here is an open access paper that covers some of the challenges that have faced the interpretation of just how and why it is that mitochondria have an important role in the aging process. The mitochondrial free radical theory of agi... Read Post


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