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Specific protein triggers changes in neurons in brain reward center linked to cocaine addiction

New research reveals that repeated exposure to cocaine decreases the activity of a protein necessary for normal functioning of the brain's reward system, thus enhancing the reward for cocaine use, which leads to addiction. Investigators were also able to block the ability of repeated cocaine exposure, to induce addiction.
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Mount Sinai Researchers Find Promising New Drug Targets for Cocaine Addiction

Health : Newswise Medical News (8 months ago)

Finding suitable drug targets for treating cocaine addiction has proved daunting, but for the first time, researchers have shown that abundant enzyme PARP-1 and the sidekick-1 gene are found to enhance the brain's reward system. Read Post

Opioid Abuse Initiates Specific Protein Interactions in Neurons in Brain's Reward System

Health : Newswise Medical News (7 months ago)

Opiate use triggers changes in the protein RGS9-2 in neurons in the brain's reward center. Repeated use affects analgesic relief and tolerance, as well as addiction. Read Post

Specific protein triggers changes in neurons in brain reward center linked to cocaine addiction

Academics / General Science : Science Codex (2 years ago)

New research from Mount Sinai Medical Center in New York reveals that repeated exposure to cocaine decreases the activity of a protein necessary for normal functioning of the brain's reward system, thus enhancing the reward for coca... Read Post


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