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New method IDs up to twice as many proteins and peptides in mass spectrometry data

An international team of researchers developed a method that identifies up to twice as many proteins and peptides in mass spectrometry data than conventional approaches. The method can be applied to a range of fields, including clinical settings and fundamental biology research for cancer and other diseases. The key to the new method's improved performance is its ability to compare data to so-called spectral libraries--essentially a pattern-matching exercise--rather than individual spectra or a database of sequences.
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