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Chemotherapy may be better for certain patients with advanced lung cancer

Academics / General Science : Science Codex

Among patients with advanced non-small cell lung cancer without a mutation of a certain gene (EGFR), conventional chemotherapy, compared with treatment using epidermal growth factor receptor tyrosine kinase inhibitors, was associate...

Afatinib shows clinical benefit for lung cancer patients with brain metastases

Academics / General Science : Science Codex

DENVER - Non-small cell lung cancer (NSCLC) patients with common epidermal growth factor (EGFR) mutations and brain metastases showed improved progression-free survival (PFS) and response from the EGFR tyrosine kinase inhibitor (TKI...

Smoking Status Seems To Be Most Important Prognostic Factor, Not EGFR Mutation, In Non-Small Cell Lung Cancer

Health : Medical News Today

Recent studies have demonstrated that molecular-targeted agents, such as epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKI), may prolong survival of selected patients based on tumor biomarkers. The presence of ...

Osimertinib given as first-line treatment may alter biology of EGFR mutated NSCLC

Academics / General Science : Science Codex

GENEVA, Switzerland, 14 April 2016 - The third generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) osimertinib is effective in the first-line treatment of EGFR mutated non-small-cell lung cancer (NSCLC...

Combining RNA Interference With Tyrosine Kinase Inhibitors Or Cetuximab Enhances Lung Cancer Therapy

Health : Medical News Today

Non-small cell lung cancer (NSCLC), the most common form of lung cancer, is usually treated with surgery and chemotherapy. However, a small group of patients can also be helped by treatment with tyrosine kinase inhibitors (TKI). New...

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