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Immune-matched stem cells prevent rejection of retinal transplants in animals

(Cell Press) Stem cell-based transplantation approaches hold great potential for treating a wide range of eye diseases, but progress has been limited by concerns about cost, safety, and effectiveness. In two related studies, published Sept. 15 in Stem Cell Reports, scientists in Japan overcame a part of these concerns by demonstrating the successful transplantation of stem cell-derived retinal cells generated from immunologically matched donor animals without the need for harmful immunosuppressants.
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