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Bone marrow inflammation predicts leukemia risk

(Cell Press) Cancer is generally thought to arise from genetic damage within individual cells, but recent evidence has suggested that abnormal signaling in the surrounding tissue also plays an important role. In a study published Sept. 22 in Cell Stem Cell, researchers show that inflammatory signaling in the bone marrow tumor environment is a key driver of malignancy and predicts the development of leukemia in mice and humans.
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