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Study identifies a potential biomarker for pancreatic tumor grade

(JCI Journals) This month in the JCI, a team led by Richard Tomasini at INSERM analyzed the expression of proteins in PDA tumors to determine how cells in the tissue surrounding tumors contribute to tumor aggressiveness. They found that cells in tumor-surrounding tissue supported increased tumor growth and metastasis in PDA tumors when they contained extracellular vesicles that expressed a protein called annexin 6.
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