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Arizona Cardinals vs. San Francisco 49ers Betting Odds, Analysis, NFL Pick

The Arizona Cardinals could be without injured quarterback Carson Palmer when they attempt to end a two-game straight up and against the spread losing streak Thursday night against the San Francisco 49ers at Levi's Stadium. The Cardinals are coming off a pair of outright losses as favorites, opening at 1-3 SU for the first time since 2011 while going 2-5 SU and 1-6 ATS over their past seven contests.
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