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UT Southwestern study shows how certain drugs alter metabolism of pancreatic cancer cells

Academics / General Science : Science Codex

DALLAS - Jan. 21, 2016 - UT Southwestern Medical Center researchers have found that cancer drugs known as CDK4/6-inhibitors alter the metabolism of pancreatic cancer cells, revealing a biologic vulnerability that could be exploited ...

How certain drugs alter metabolism of pancreatic cancer cells

Academics / General Science : ScienceDaily: Science Society

Cancer drugs known as CDK4/6-inhibitors alter the metabolism of pancreatic cancer cells, revealing a biologic vulnerability that could be exploited for therapeutic gain, researchers have found.

Study characterizes insulin secretion in response to metabolic stress

Academics / General Science : Science Codex

The development of type 2 diabetes is linked to persistent inflammation as a consequence of metabolic stress. Prolonged exposure to the proinflammatory molecule IL-1? is associated with reduced insulin secretion by pancreatic ? cell...

Mutant Kras drives pancreatic cancer maintenance via metabolic pathways

Academics / General Science : Science Codex

HOUSTON - A genetic mutation that drives the initiation of pancreatic cancer also manipulates metabolic pathways to support tumor growth and progression, scientists report in the journal Cell. This newly discovered role for the Kras...

Study reveals unexpected cell hijack method in pancreatic cancer

Academics / General Science : Science Codex

Pancreatic stellate cells, which normally aid tissue repair, unwittingly help pancreatic cancer grow and spread in a method of 'cell hijack' only seen before in brain and breast cancer, according to new research from Queen Mary Univ...

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