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Research Uncovers Defender Against Cancer-Promoting Liver Damage

The liver reacts to chronic injury by walling it off with scar tissue and calling in immune cells with inflammatory signals. If cancer arises, the resulting inflammation then stokes tumor progression. Scientists at the Sanford Burnham Prebys Medical Discovery Institute (SBP) have discovered that a key signaling protein helps suppress inflammation and scarring. The results, published today in Cancer Cell, represent another foundational step towards better treatments for liver cancer.
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(Sanford-Burnham Prebys Medical Discovery Institute) The liver reacts to chronic injury by trying to wall it off with scar tissue and calling in immune cells with inflammatory signals. If cancer arises, the resulting inflammation th...

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