Ospreys are without Jeff Hassler and Tyler Ardron as they face Newcastle Falcons in their first-ever European Challenge Cup tie.
Team news as Connacht host Newcastle in Friday's European Rugby Challenge Cup fixture at Galway (19:45 GMT).
Team news as Newcastle visit Brive in Friday's European Challenge Cup fixture at Stade Amedee-Domenech (18:30 GMT).
Canadian wing Jeff Hassler signs a one-year extension to remain with the Ospreys until 2018.
Team news as Harlequins host Stade Francais in Thursday's European Rugby Challenge Cup fixture at The Stoop (19:45 BST).