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Untangling a cause of memory loss in neurodegenerative diseases

(NIH/National Institute of Neurological Disorders and Stroke) In mice genetically engineered to mimic aspects of human tauopathy disorders, the researchers restored some of the learning and memory deficits by blocking caspase-2 activity, which suggests that some of the cognitive loss seen in tauopathies might be reversible. The study was funded by the National Institutes of Health's National Institute of Neurological Disorders and Stroke and published in the journal Nature Medicine.
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