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N-acetyl cysteine improves efficacy of adoptive T cell immunotherapy for melanoma

(Medical University of South Carolina) Boosting the immune system's cancer-fighting ability is the aim of adoptive T cell immunotherapy, in which the patient's T cells are harvested, expanded, and then reinfused. Ensuring T cell persistence after reinfusion has been a challenge. In the Oct. 15, 2016 Cancer Research, investigators at the Medical University of South Carolina and Loyola University report that culturing T cells in N-acetyl cysteine significantly improves persistence.
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