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Super-photostable fluorescent labeling agent for super-resolution microscopy

(Institute of Transformative Bio-Molecules (ITbM), Nagoya University) Chemists at ITbM, Nagoya University have developed a super-photostable fluorescent dye, PhoxBright 430 (PB430), to visualize cellular ultrastructure by super resolution microscopy. The exceptional photostability of this new dye enables continuous STED imaging and together with its ability to fluorescently label proteins, PB430 demonstrates its use in the 3D construction and multicolor imaging of biological structures.
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