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Histone 1, the guardian of genome stability

(Institute for Research in Biomedicine (IRB Barcelona)) Genomic instability is the main risk factor for tumor development in humans. Therefore understanding its origin and and exploring therapeutic targets is paramount.Histone 1 silences a region of the genome that causes irreparable DNA damage when translated and is lethal for the organism.
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Histone 1, the guardian of genome stability

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Genomic instability is the main risk factor for tumor development in humans. Therefore understanding its origin and and exploring therapeutic targets is paramount. Histone 1 silences a region of the genome that causes irreparable DN...

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