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How whip-like cell appendages promote bodily fluid flow

(Nagoya University) Researchers at Nagoya University revealed that a molecule called Daple is essential for the correct orientation and coordinated beating of cilia on the surface of cells lining ventricles in the brain. Without Daple, the cilia develop a random arrangement and cannot produce a uniform flow of CSF. This in turn leads to a build-up of fluid, which is associated with swelling of the head, known as hydrocephalus.
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