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Circadian Clock's Inner Gears

New study identifies a handful of molecular machines that run circadian clocks, biomechanical oscillators that control physiology, metabolism and behavior on a 24-hour cycle. Findings dispel traditional view that key clock proteins act individually and provide the first structural glimpse of the body's circadian machine. Identifying protein complexes that operate the circadian clock could eventually lead to new treatments for disorders stemming from malfunctions in the system, including sleep problems, metabolic problems and cancer.
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