Post Profile






More Evidence for Senescent Cell Signaling to be a Cause of Age-Related Fibrosis

Regeneration and tissue maintenance are highly complex, regulated processes. Unfortunately, these processes run awry as the low-level molecular damage of aging increases over the years. Cells change their behavior, change the signals they produce, and one of the detrimental outcomes of these changes is fibrosis. This is the creation of scar-like collagen structures in place of the expected arrangement of cells and extracellular matrix.
read more

share

Related Posts


Senescent Cells May Enhance Viral Replication, Making Infections More Dangerous

Health / Aging : Fight Aging

An accumulation of senescent cells is one of the causes of degenerative aging. These cells secrete a mix of inflammatory and other signal molecules, producing numerous detrimental changes in surrounding tissues. As the number of sen...

Cellular Senescence in Aging as Adapted Tool of Development

Health / Aging : Fight Aging

An accumulation of senescent cells is one of the causes of degenerative aging. These are damaged or otherwise dysfunctional cells than stop dividing and start issuing signals that are disruptive to surrounding tissues. They should b...

Linking the Bad Behavior of Senescent Cells with Innate Immune Mechanisms

Health / Aging : Fight Aging

Senescent cells accumulate in tissues with age, and while they make up a comparatively small fraction of all cells even in late life, they nonetheless cause great harm. These cells actively secrete a potent mix of signals, the senes...

On the Topic of Senescent Cells: Should We All be Trying to Take Navitoclax?

Health / Aging : Fight Aging

Senescent cells accumulate with age, and secrete an unfortunate combination of signals that harms organs and tissues in numerous ways, such as via the production of increased chronic inflammation. This is one of the root causes of a...

Senescent Cells Implicated as a Cause of Idiopathic Pulmonary Fibrosis

Health / Aging : Fight Aging

The number of senescent cells in tissues grows with age, and these cells cause harm through forms of signaling that induce inflammation, destructively remodel the extracellular matrix, and alter the behavior of other cells for the w...

Comments


Copyright © 2016 Regator, LLC