Post Profile

Does Blood Pressure Decrease in Late Life, and Why Would this Happen?

Blood pressure tends to increase with age, ultimately producing clinical hypertension in a sizable fraction of the population. This is driven by the progressive stiffening of blood vessels, which breaks the finely tuned feedback system that reacts to and controls blood pressure. Stiffening of blood vessels is in turn caused by factors such as calcification and inflammation resulting from cellular senescence, as well as cross-linking in the extracellular matrix that degrades tissue elasticity, and dysfunction of the muscle tissue that controls contraction and dilation of blood vessels.
read more


Related Posts

Hypertension Causes Brain Damage

Health / Aging : Fight Aging

The stiffening of blood vessels due to cross-linking in the extracellular matrix and other factors such as calcification is known to cause hypertension, and the elevated blood pressure of hypertension causes progressive damage to br...

MMP12 as a Mediator of Arterial Stiffening

Health / Aging : Fight Aging

Loss of elasticity in blood vessels is an important aspect of aging, as it creates hypertension and cardiovascular remodeling that ultimately leads to heart disease and death, along the way increasing the damage done by blood vessel...

Examining the Relationship Between Hypertension and Cognitive Decline

Health / Aging : Fight Aging

Blood pressure increases with age, driven by loss of elasticity in blood vessels, among other things, leading to the medical condition of hypertension. Here, researchers examine the complex associations between higher blood pressure...

A Measure of Just How Beneficial Clearing Cross-Links Might be for the Old

Health / Aging : Fight Aging

Hypertension, increased blood pressure with age, is caused by stiffening of blood vessels. That stiffening is in turn caused by some combination of cross-linking, cellular senescence, calcification, and inflammation. Cross-linking i...

Hypertension Causes Neural Damage in Part via Altered Macrophage Behavior

Health / Aging : Fight Aging

The increased blood pressure of age-related hypertension is driven by the stiffening of blood vessels. It harms fragile tissues, such as those of the kidney, directly through the physical processes of greater pressure. It also incre...


Copyright © 2016 Regator, LLC