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First Total Synthesis of Ceanothine D

Proposed structure of a cyclopeptide alkaloid found in red root synthesized
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(University of Pittsburgh) Alkaloids are natural nitrogen-containing compounds produced by plants and microbes. These molecules, such as morphine and quinine, are important human medicines. Alkaloids are typically polycyclic in natu...

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In 1928, chemists Otto Diels and Kurt Alder first documented diene synthesis, a chemical reaction important for synthesizing many polymers, alkaloids and steroids. Their work on this mechanism, which came to be known as the Diels–Al...

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