Scientists have transformed skin cells from patients with Huntington's disease into the type of brain cell affected by the disorder. The resulting mass of neurons serves as a new tool to study the degenerative and eventually fatal neurological condition, according to the researchers.
(Washington University School of Medicine) Scientists at Washington University School of Medicine in St. Louis have transformed skin cells from patients with Huntington's disease into the type of brain cell affected by the disorder.Show More Summary
Pictured are reprogrammed cells from a 71-year-old patient with Huntington's disease. Originally skin cells, these have been converted into medium spiny neurons, the cell type affected in Huntington's disease. Sampling skin cells from...Show More Summary
Scientists have established a mouse model for the human disease SCA6. SCA6 is characterized by movement deficits and caused by similar genetic alterations as Chorea Huntington. The mouse model will be used to investigate the disease mechanisms. Experiments suggest that an impairment of eye blink conditioning could be an early disease symptom.
A preclinical, large animal model of Huntington's disease has been developed for assessing new therapeutics, which could ultimately provide better treatment options, possibly including altering the course of the disease.
Over the weekend, the Backyard Skeptics in Orange County, California gathered at Huntington Beach because they planned to tear certain pages out of the Bible. When uproar ensued, they altered their plans a bit — they decided to rip up … Continue reading ?