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End-of-life hospital and healthcare use among older adults with Alzheimer's disease

3 minutes agoHealth : EurekAlert: Health

(American Geriatrics Society) A team of researchers from Belgium recently studied how people with Alzheimer's disease use medical services during their final months. The goal was to learn more about the best ways to help older adults with dementia at the end of their lives. Their study was published in the Journal of the American Geriatrics Society.

Arguing for Tau to be More Important than Amyloid-? in Alzheimer's Disease

8 hours agoHealth / Aging : Fight Aging

This isn't the first paper I've seen to argue the point that there should be a greater focus on tau aggregation in Alzheimer's disease, and that tau may be more important to the progression of the condition. As I'm sure the readers here are aware, Alzheimer's is characterized by the buildup of both amyloid-? and tau in the brain. Show More Summary

Data detectives shift suspicions in Alzheimer's from usual suspect to inside villain

(Georgia Institute of Technology) The pursuit of the usual suspect in Alzheimer's research may be distracting from a more direct culprit in the disease, according to a study that analyzed data from 51 published experiments. P-tau looked a good bit more culpable than amyloid-beta plaque.

Neurons Fight Back Early in Brain Disease

A therapeutic target to preserve vision in glaucoma patients could have treatment ramifications for age-related neurodegenerative disorders like Alzheimer's and Parkinson's, according to findings released today in the Proceedings of the National Academy of Sciences (PNAS).

Data Detectives Shift Suspicions in Alzheimer's from Usual Suspect to Inside Villain

The pursuit of the usual suspect in Alzheimer's research may be distracting from a more direct culprit in the disease, according to a study that analyzed data from 51 published experiments. P-tau looked a good bit more culpable than amyloid-beta plaque.

"In Pursuit of Memory" author on the future of treating Alzheimer's

Alzheimer's disease is a growing health crisis with more than five million Americans estimated to have it. That number could top 15 million by 2050. British neuroscientist Dr. Joseph Jebelli has studied Alzheimer's throughout his career...Show More Summary

FDA opens new path for Alzheimer's therapy as failures mount

U.S. drug regulators want to let drugmakers test Alzheimer's disease treatments on patients years before the disease shows outward signs, and could approve the therapies based on subtle biological signals rather than proof they alleviate symptoms. The Food and Drug Administration proposal will...

Not being aware of memory problems predicts onset of Alzheimer's disease

(McGill University) Doctors who work with individuals at risk of developing dementia have long suspected that patients who do not realize they experience memory problems are at greater risk of seeing their condition worsen in a short time frame, a suspicion that now has been confirmed by a team of McGill University clinician scientists.

Alzheimer's drug repairs brain damage after alcohol binges in rodents

(Duke University Medical Center) A drug used to slow cognitive decline in Alzheimer's disease could offer clues on how drugs might one day be able to reverse brain changes that affect learning and memory in teens and young adults who binge drink.

BACE1 Deletion Eliminates Amyloid Deposits in a Mouse Model of Alzheimer's Disease

6 days agoHealth / Aging : Fight Aging

BACE1 is one of the proteins involved in early stages of the production of amyloid-?, a form of metabolic waste that aggregates into solid deposits in the aging brain, and is characteristic of Alzheimer's disease. Inhibition of BACE1...Show More Summary

Surgical instruments may spread Alzheimer’s proteins

Amyloid protein, which is linked to Alzheimer’s disease, may be spread via surgical implements, but there isn’t evidence yet that this can transmit the disease

New study reverses Alzheimer's in mice, while similar big clinical trial fails

6 days agoTechnology / Gadgets : Gizmag

A new study has successfully reversed both the biological and behavioral hallmarks of Alzheimer's disease in mouse models. The research found that slowly depleting the presence of a certain enzyme can reverse the formation of amyloid plaques in the brain. Show More Summary

Poor fitness linked to weaker brain fiber, higher dementia risk

Scientists have more evidence that exercise improves brain health and could be a lifesaving ingredient that prevents Alzheimer's disease.

Pimavanserin: Relief from psychosis in dementia, without devastating side-effects

New research has found that pimavanserin significantly improves psychosis symptoms in people with Alzheimer's disease, without the devastating side-effects of currently used antipsychotics. The research found an even greater benefit in those with the most severe psychotic symptoms.

Can Nicotinamide Riboside Help Prevent Alzheimer's?

The supplement nicotinamide riboside (NR) – a form of vitamin B3 – prevented neurological damage and improved cognitive and physical function in a new mouse model of Alzheimer’s disease. by Alzheimer's Reading Room The results of the...Show More Summary

Poor fitness linked to weaker brain fiber, higher dementia risk

(UT Southwestern Medical Center) Scientists have more evidence that exercise improves brain health and could be a lifesaving ingredient that prevents Alzheimer's disease.

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