(Baylor College of Medicine) Sunduing early disease events and the subsequent development of brain pathology in experimental animal models prevents Alzhemer's disease.
(Baylor College of Medicine) A novel genetic risk factor for late-onset Alzheimer's disease among Icelanders.
(University of Arizona Health Sciences) Why do more women than men get Alzheimer's disease? In their quest to find the answer, neuroscientist Roberta Diaz Brinton, Ph.D., and her colleagues in the Center for Innovation in Brain Science...Show More Summary
New Alzheimer's treatment could be delivered as nasal spray, say scientists. Researchers have developed a novel treatment that could block the development of Alzheimer's disease using microscopic droplets of fat to carry drugs into the brain. Show More Summary
A major advance has been made in Alzheimer’s research, say researchers. They showed how a diseased vertebrate brain can naturally react to Alzheimer’s pathology by forming more neurons. Two proteins (Interleukin-4 and STAT6) have been identified to be relevant for this process. Show More Summary
(PLOS) People with Icelandic heritage are more likely to carry a novel rare mutation in the TM2D3 gene, which leads to greater risk for Alzheimer's disease, based on a new study published Oct. 14, 2016, in PLOS Genetics by Johanna Jakobsdottir of the Icelandic Heart Association, Sven van der Lee of Erasmus University in Rotterdam, and colleagues.
Neurostimulation is being investigated as a tool used to treat many neurological disorders, like depression, Alzheimer disease, Parkinson disease, bipolar disorder, schizophrenia, and addiction. For most of these conditions, neurostimulation...Show More Summary
A key strategy missing from the ambitious Alzheimer's disease plan signed into law by President Obama six years ago could send investigational drugs down a precarious pipeline, argue two physicians.
(DZNE - German Center for Neurodegenerative Diseases) Patients with Alzheimer's or other neurodegenerative diseases progressively loose neurons yet cannot build new ones. However, modulating the immune response might help the human brain to better cope with such conditions and regenerate. Show More Summary
A rare variant in the TM2D3 gene is linked to increased risk and earlier onset of Alzheimer’s disease, say researchers, who have discovered that this mutation is more commonly found in Icelandic people.
(Boston University Medical Center) Sudha Seshadri, MD, professor of neurology at Boston University School of Medicine (BUSM), has been awarded three grants this year totaling nearly $20 million from the National Institute on Aging (NIA) and the National Institute of Neurological Disorders and Stroke (NINDS). Show More Summary
The troublesome symptoms of dementia may actually be caused by an unrelated problem whose symptoms copycat Alzheimer’s disease. Dr. Gary Small, a noted expert on Alzheimer’s disease and co-author with Gigi Vorgan of the best-sellingShow More Summary
Police and family members are asking the public to help find a 55-year-old woman with Alzheimer’s disease who went missing during a visit to the Los Angeles County Museum of Art. Nancy Paulikas was last seen exiting the restroom at LACMA about 3 p.m. Saturday. She appeared to walk toward a museum...
It is always a good idea to look closely at the biochemistry involved in any potential Alzheimer's disease therapy that shows promise in mouse models. There is perhaps more uncertainty for Alzheimer's than most other age-related conditions...Show More Summary
A rare variant in the TM2D3 gene linked to increased risk and earlier onset of Alzheimer's disease.
Alzheimer’s disease and dementia progression and onset are linked to chronic sleep disturbances. Study lead Domenico Praticò explained, “The big biological question that we tried to address in this study is whether sleep disturbanceShow More Summary
Tauopathies are a group of neurodegenerative disorders, including Alzheimer's disease that are characterized by the deposition of aggregates of the tau protein inside brain cells. A new study reveals that the cutting of tau by an enzyme called caspase-2 may play a critical role in the disordered brain circuit function that occurs in these diseases. Show More Summary
Mild cognitive impairment (MCI) patients with anxiety face faster Alzheimer’s disease progression. The risk of Alzheimer’s disease in mild cognitive impairment patients with mild, moderate, and severe anxiety was found to increase by...Show More Summary
There is some evidence for the deposition of misfolded proteins into solid structures known as amyloid to contribute to the development of arthritis. Amyloid is better known for its role in Alzheimer's disease, but there are a number...Show More Summary
Researchers have confirmed that mutation-caused dysfunction in a process cells use to transport molecules within the cell plays a previously suspected but underappreciated role in promoting the heritable form of Alzheimer's disease, but also one that might be remedied with existing therapeutic enzyme inhibitors.