If surveying what is known of the pathology of age-related conditions, we find an array of cellular damage and metabolic waste accumulation that happens in everyone. The people with medical conditions have a lot more of one or more types of this damage and waste, however. Show More Summary
Gout, an extremely painful form of arthritis, may be linked to a reduced risk for Alzheimer’s disease.
Heart function has been associated with the development of dementia and Alzheimer's disease through a new study. Participants with decreased heart function, measured by cardiac index, were two to three times more likely to develop significant memory loss over the follow-up period.
The cognitive performance of persons with Alzheimer's disease and behavioral and psychological problems are linked to their performance of activities of daily living, according to a recent study. However, difficulties in cognitive performance...Show More Summary
Doctors write millions of prescriptions a year for drugs to calm the behavior of people with Alzheimer's disease and other types of dementia. But non-drug approaches actually work better, and carry far fewer risks, experts conclude in a new report.
Research related to cardiovascular, respiratory, and neurodegenerative diseases; cancer; food safety; biotechnology; and pharmaceuticals, among others, will be presented and discussed from March 22-26, 2015, at the San Diego Convention Center as part of the 54th Annual Meeting and ToxExpo of the Society of Toxicology (SOT).
Researchers have identified a promising new target in the battle against certain neurological diseases. A protein known as TREM2 has been proven effective in clearing away unwanted debris in the brain, the unchecked buildup of which can lead to both Alzheimer's disease and multiple sclerosis (MS)... Show More Summary
Scientists know that Alzheimer’s disease gains a foothold in a patient’s brain years before he or she first stashes car keys in the freezer, or gets lost coming home from the store. But a new study suggests that the changes in the brain that set the stage for Alzheimer’s may...
Yellow also is a color of angels, and in scripture it symbolizes a change for the better. My mom, who died of Alzheimer’s in a bruising battle with the disease, believed in angels. So do I, in the wake of my own diagnosis five years ago of Early Onset Alzheimer’s. Yellow—derived from the ancient Latin “Angelus,” translated “messenger” or “envoys”— resonates with peace.
A deficiency in the protein responsible for moving glucose across the brain's protective blood-brain barrier appears to intensify the neurodegenerative effects of Alzheimer's disease, according to a new mouse study. The research suggests that targeting the protein called GLUT1 could help prevent or slow the effects of Alzheimer's, especially among those at risk for the disease.
Amyloid -- an abnormal protein whose accumulation in the brain is a hallmark of Alzheimer's disease -- starts accumulating inside neurons of people as young as 20, a much younger age than scientists ever imagined, reports a surprising...Show More Summary
The brain-damaging protein in Alzheimer’s disease may start accumulating as early as in our 20s
Discovering that amyloid begins to accumulate so early in life is unprecedented in Alzheimer's research. By Alzheimer's Reading Room Amyloid -- an abnormal protein whose accumulation in the brain is a hallmark of Alzheimer's diseaseShow More Summary
In this Mayo Clinic Radio Health Minute, Dr. Keith Josephs comments on a study which may have found a new culprit when it comes to Alzheimer's disease. To listen, click the link below. TDP43 Study
Highlighting a potential target in the treatment of multiple sclerosis (MS) and Alzheimer's disease, new research suggests that triggering a protein found on the surface of brain cells may help slow the progression of these and other neurological diseases.
Researchers show that toning down the activity of the receptor TREM2 may help put a stop to neurodegeneration in Alzheimer's disease.
For the first time, scientists show that amyloid protein - a hallmark of Alzheimer's disease - can start to accumulate in the brain when we are 20 years old.
Mitochondrial dysfunction is a hallmark of neurodegenerative diseases including Alzheimer's disease (AD), with morphological and functional abnormalities limiting the electron transport chain and ATP production. A contributing factor of mitochondrial abnormalities is loss of nicotinamide adenine dinucleotide (NAD), an important cofactor in multiple metabolic reactions. read more
By Alzheimer's Reading RoomI thought some of you might find this information about the hippocampus and memory of interest. Ihe hippocampus is the first area of the brain affected by Alzheimer's disease.Excerpt from the article.The hippocampus...Show More Summary
"Our ultimate goal is to develop effective drug therapies at three different points in the pathological cascade of the disease to prevent, inhibit and cure Alzheimer’s." Building on its enormously successful “Whole Genome Sequencing”...Show More Summary