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Study reveals potential new strategy to prevent Alzheimer's disease

(Baylor College of Medicine) Sunduing early disease events and the subsequent development of brain pathology in experimental animal models prevents Alzhemer's disease.

International team discovers novel Alzheimer's disease risk gene among Icelanders

(Baylor College of Medicine) A novel genetic risk factor for late-onset Alzheimer's disease among Icelanders.

UA receives $10.3 million to help unlock the mystery of Alzheimer's in women

(University of Arizona Health Sciences) Why do more women than men get Alzheimer's disease? In their quest to find the answer, neuroscientist Roberta Diaz Brinton, Ph.D., and her colleagues in the Center for Innovation in Brain Science...Show More Summary

Treatment approach used in cancer holds promise for Alzheimer's disease

New Alzheimer's treatment could be delivered as nasal spray, say scientists. Researchers have developed a novel treatment that could block the development of Alzheimer's disease using microscopic droplets of fat to carry drugs into the brain. Show More Summary

Advances made in Alzheimer's research

A major advance has been made in Alzheimer’s research, say researchers. They showed how a diseased vertebrate brain can naturally react to Alzheimer’s pathology by forming more neurons. Two proteins (Interleukin-4 and STAT6) have been identified to be relevant for this process. Show More Summary

Newly identified rare Alzheimer's disease gene mutation more common in Icelandic people

(PLOS) People with Icelandic heritage are more likely to carry a novel rare mutation in the TM2D3 gene, which leads to greater risk for Alzheimer's disease, based on a new study published Oct. 14, 2016, in PLOS Genetics by Johanna Jakobsdottir of the Icelandic Heart Association, Sven van der Lee of Erasmus University in Rotterdam, and colleagues.

Neurostimulation for Drug Addiction: Therapy of the Future

Neurostimulation is being investigated as a tool used to treat many neurological disorders, like depression, Alzheimer disease, Parkinson disease, bipolar disorder, schizophrenia, and addiction. For most of these conditions, neurostimulation...Show More Summary

Penn Physician Argues for "Meaningful" Update to National Alzheimer's Act

A key strategy missing from the ambitious Alzheimer's disease plan signed into law by President Obama six years ago could send investigational drugs down a precarious pipeline, argue two physicians.

Tweaking the immune response might be a key to combat neurodegeneration

(DZNE - German Center for Neurodegenerative Diseases) Patients with Alzheimer's or other neurodegenerative diseases progressively loose neurons yet cannot build new ones. However, modulating the immune response might help the human brain to better cope with such conditions and regenerate. Show More Summary

Newly identified rare Alzheimer's disease gene mutation more common in Icelandic people

A rare variant in the TM2D3 gene is linked to increased risk and earlier onset of Alzheimer’s disease, say researchers, who have discovered that this mutation is more commonly found in Icelandic people.

BU researcher awarded grants to better understand Alzheimer's disease

(Boston University Medical Center) Sudha Seshadri, MD, professor of neurology at Boston University School of Medicine (BUSM), has been awarded three grants this year totaling nearly $20 million from the National Institute on Aging (NIA) and the National Institute of Neurological Disorders and Stroke (NINDS). Show More Summary

6 Treatable Conditions That Mimic Dementia

3 days agoNews : Huffington Post

The troublesome symptoms of dementia may actually be caused by an unrelated problem whose symptoms copycat Alzheimer’s disease. Dr. Gary Small, a noted expert on Alzheimer’s disease and co-author with Gigi Vorgan of the best-sellingShow More Summary

Family asks for public's help finding woman with Alzheimer's disease who vanished at LACMA

Police and family members are asking the public to help find a 55-year-old woman with Alzheimer’s disease who went missing during a visit to the Los Angeles County Museum of Art. Nancy Paulikas was last seen exiting the restroom at LACMA about 3 p.m. Saturday. She appeared to walk toward a museum...

PGC-1? Gene Therapy Slows Alzheimer's Progression in Mouse Model

4 days agoHealth / Aging : Fight Aging

It is always a good idea to look closely at the biochemistry involved in any potential Alzheimer's disease therapy that shows promise in mouse models. There is perhaps more uncertainty for Alzheimer's than most other age-related conditions...Show More Summary

Newly Identified Rare Alzheimer's Disease Gene Mutation More Common in Icelandic People

A rare variant in the TM2D3 gene linked to increased risk and earlier onset of Alzheimer's disease.

Alzheimer’s disease, dementia progression and onset linked to chronic sleep disturbances, poor sleep quality

Alzheimer’s disease and dementia progression and onset are linked to chronic sleep disturbances. Study lead Domenico Praticò explained, “The big biological question that we tried to address in this study is whether sleep disturbanceShow More Summary

Untangling a cause of memory loss in neurodegenerative diseases

Tauopathies are a group of neurodegenerative disorders, including Alzheimer's disease that are characterized by the deposition of aggregates of the tau protein inside brain cells. A new study reveals that the cutting of tau by an enzyme called caspase-2 may play a critical role in the disordered brain circuit function that occurs in these diseases. Show More Summary

Mild cognitive impairment patients with anxiety face faster Alzheimer’s disease progression: Study

Mild cognitive impairment (MCI) patients with anxiety face faster Alzheimer’s disease progression. The risk of Alzheimer’s disease in mild cognitive impairment patients with mild, moderate, and severe anxiety was found to increase by...Show More Summary

More Evidence for Transthyretin Amyloid to Associate with Osteoarthritis

last weekHealth / Aging : Fight Aging

There is some evidence for the deposition of misfolded proteins into solid structures known as amyloid to contribute to the development of arthritis. Amyloid is better known for its role in Alzheimer's disease, but there are a number...Show More Summary

Dysfunction in neuronal transport mechanism linked to Alzheimer's disease

Researchers have confirmed that mutation-caused dysfunction in a process cells use to transport molecules within the cell plays a previously suspected but underappreciated role in promoting the heritable form of Alzheimer's disease, but also one that might be remedied with existing therapeutic enzyme inhibitors.

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