One component of most neurodegenerative diseases is that classes of immune cells resident in the brain adopt disruptive, inflammatory behaviors. This is a reaction in some way to growing levels of damage in the form of aggregated proteins, such as amyloid-? and tau in Alzheimer's disease, but it isn't a helpful reaction. Show More Summary
Researchers from the University of Bari in Italy have created algorithms that can analyze MRI scans to identify structural changes in the brain that signify a person is afflicted with the disease, reports the Times. Unlike human doctors, the AI doesn’t need to specifically be told to looks for signs of Alzheimer’s in brain scans. Show More Summary
People with chronic gum inflammation for 10 or more years were 70 percent more likely than people without periodontitis to develop Alzheimer’s disease.
A new study challenges the traditional understanding of Alzheimer's disease, as scientists point to a new gene that may be responsible for the illness.
On Friday, Sept. 22, UCI MIND and Alzheimer's Orange County will co-host the 28th Annual Southern California Alzheimer's Disease Research Conference, themed "The Elephant in the Room: Sensitive Subjects in Dementia Care." It will highlight...Show More Summary
Physical aggression among people with dementia is not unusual. A study showed that one-third of patients with the diagnosis Alzheimer’s disease or frontotemporal dementia were physically aggressive towards healthcare staff, other patients, relatives, animals and complete strangers. This manifestation of disease must be both understood and addressed in the right way.
Scientific literature in recent years has focused extensively on one genetic risk factor for Alzheimer's disease, the ApoE4 gene variant. A recent study raises flags that scientists should investigate another important player, the TOMM40 gene.
A new study shows that hypometabolism in the medial prefrontal areas is specifically associated with Alzheimer's disease-related nutritional problems, and decrease in fat mass may have a key role.
(IOS Press) Obu, Japan, September 15, 2017 - A new study from the Multimodal Neuroimaging for AD Diagnosis (MULNIAD) study, which is a prospective study implemented at the National Center for Geriatrics and Gerontology (NCGG), provides...Show More Summary
Alzheimer’s disease is one of those conditions where genetics is known to play a profound role but is not the sole factor in disease development and progression. The evidence is mounting that the environment has a great deal to do with the development of this neurodegenerative disorder. Moreover, it is now known that the right […]
The notorious genetic marker of Alzheimer's disease and other forms of dementia, ApoE4, may not be a lone wolf. Researchers from USC and the University of Manchester have found that another gene, TOMM40, complicates the picture. Although ApoE4 plays a greater role in some types of aging-related memory ability, TOMM40 may pose an even greater risk for other types.
(University of Southern California) Scientific literature in recent years has focused extensively on one genetic risk factor for Alzheimer's disease, the ApoE4 gene variant. A recent study published in PLOS ONE raises flags that scientists should investigate another important player, the TOMM40 gene.
A machine-learning algorithm that examines MRI scans can identify alterations in how different regions of the brain are connected that indicate future disease
/PRNewswire-USNewswire/ -- Nearly 200 academic and industry researchers came together to share updates on preclinical and clinical-stage Alzheimer's disease research at the 18th Annual Conference on Alzheimer's Drug Discovery. The two-day...Show More Summary
(Lund University) Physical aggression among people with dementia is not unusual. A study from Lund University in Sweden showed that one-third of patients with the diagnosis Alzheimer's disease or frontotemporal dementia were physically aggressive towards healthcare staff, other patients, relatives, animals and complete strangers. Show More Summary
(Mary Ann Liebert, Inc./Genetic Engineering News) A new study has demonstrated the potential to use a frequency distribution-based index of brain functional connectivity as a biomarker for detecting Alzheimer's disease and mild cognitive impairment.
The simple new technique could offer vastly superior predictions of disease severity in a huge range of conditions with a genetic component, including Alzheimer's, autism, cancer, cardiovascular disease, diabetes, obesity, schizophrenia and depression.
(University of Virginia Health System) The simple new technique could offer vastly superior predictions of disease severity in a huge range of conditions with a genetic component, including Alzheimer's, cancer, cardiovascular disease, diabetes, obesity, schizophrenia and depression.
A team of researchers has determined the structure of an amyloid fibril with previously unachieved resolution. The fibrils of the body's own amyloid beta protein are the main constituent of Alzheimer's disease related and characteristic pathological protein deposits in the brain. Show More Summary
In the largest and most conclusive study of its kind, researchers have analyzed blood samples to create a novel and non-invasive way of helping to diagnose Alzheimer's disease and distinguishing between different types of neurodegenerative disorders. Show More Summary