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Researchers discover new enzymes central to cell function

(Case Western Reserve University) Doctors have long treated heart attacks, improved asthma symptoms, and cured impotence by increasing levels of a single molecule in the body: nitric oxide. The tiny molecule can change how proteins function. Show More Summary

Researchers develop swallowable test to detect pre-cancerous Barrett's esophagus

(Case Western Reserve University) Investigators at Case Western Reserve University School of Medicine and University Hospitals Cleveland Medical Center have developed a simple, swallowable test for early detection of Barrett's esophagus that offers promise for preventing deaths from esophageal adenocarcinoma.

For Better Customer Service, Offer Options, Not Apologies

Jagdip Singh, a professor of marketing at the Weatherhead School of Management at Case Western Reserve University, explains his research team’s new findings about customer satisfaction. He says apologizing is often counterproductive and that offering customers different possible solutions is usually more effective. Show More Summary

The presence of sexual violence in neighborhoods erodes feelings of safety

(Case Western Reserve University) Feelings about the frequency of rape or other forms of sexual assault in a neighborhood are significantly tied to women's -- but not men's -- perceptions of its safety, according to new research.

New antifungal provides hope in fight against superbugs

(Case Western Reserve University) Microscopic yeast have been wreaking havoc in hospitals around the world -- creeping into catheters, ventilator tubes, and IV lines -- and causing deadly invasive infection. One culprit species, Candida auris, is resistant to many antifungals, meaning once a person is infected, there are limited treatment options. Show More Summary

How does mothers' cocaine use during pregnancy affect boys and girls differently?

(Case Western Reserve University) With a focus on gender, new NIH-funded research continues two decades of study at Case Western Reserve University into effects of prenatal cocaine exposure.

Researchers receive $2.8 million to repurpose FDA-approved drugs to treat Alzheimer's disease

(Case Western Reserve University) Researchers from Case Western Reserve University School of Medicine and collaborators have received a five-year, $2.8 million grant from the National Institute on Aging to identify FDA-approved medications that could be repurposed to treat Alzheimer's disease. Show More Summary

Zooming in on protein to prevent kidney stones

(Case Western Reserve University) Researchers have applied Nobel prize-winning microscope technology to uncover an ion channel structure that could lead to new treatments for kidney stones. In a recent study published in Nature Structural...Show More Summary

Selective suppression of inflammation could deplete HIV and control HIV activation

(Case Western Reserve University) A class of anti-inflammatory drugs already FDA-approved for rheumatoid arthritis could 'purge' the reservoir of infected immune cells in people infected by HIV, according to new research.

Fish use deafness gene to sense water motion

Fish sense water motion the same way humans sense sound, according to new research out of Case Western Reserve University School of Medicine. Researchers discovered a gene also found in humans helps zebrafish convert water motion into electrical impulses that are sent to the brain for perception. Show More Summary

Fish use deafness gene to sense water motion

(Case Western Reserve University) Fish sense water motion the same way humans sense sound, according to new research out of Case Western Reserve University School of Medicine. Researchers discovered a gene also found in humans helps zebrafish convert water motion into electrical impulses that are sent to the brain for perception. Show More Summary

Two studies find stress reprograms cells

(Case Western Reserve University) In a pair of publications, researchers have shown how cells adapt to stressors -- like water loss -- by reprogramming their internal signaling networks. The studies describe previously unknown mechanisms that cells use to send signals between cellular machinery and avoid cell death. Show More Summary

Researchers find possible markers for earlier diagnosis of aggressive tongue cancer

(Case Western Reserve University) Squamous cell carcinoma of the tongue, also known as oral tongue cancer, is an aggressive form of cancer that generally affects older people. in a new study published in Oncotarget, a team of researchers...Show More Summary

Researchers Repurpose Immune-Activating Cytokine to Fight Breast Cancer

The most lethal form of breast cancer could have a new treatment option, according to new research out of the Case Comprehensive Cancer Center at Case Western Reserve University School of Medicine. In the Proceedings of the NationalShow More Summary

Researchers repurpose immune-activating cytokine to fight breast cancer

(Case Western Reserve University) The most lethal form of breast cancer could have a new treatment option, according to new research out of the Case Comprehensive Cancer Center. In PNAS, researchers showed triple-negative breast cancer cells are highly vulnerable to interferon-? -- a potent antimicrobial that also activates the immune system. Show More Summary

Probing Alzheimer's at both ends of the spectrum

(Case Western Reserve University) Researchers from Case Western Reserve University School of Medicine have received two grant awards, in partnership with investigators from other institutions, from the National Institutes of Health to conduct major studies on Alzheimer's disease, the most common form of memory loss and other forms of dementia in older persons.

Probing Alzheimer's at Both Ends of the Spectrum

Researchers from Case Western Reserve University School of Medicine have received two grant awards, in partnership with investigators from other institutions, from the National Institutes of Health to conduct major studies on Alzheimer's disease, the most common form of memory loss and other forms of dementia in older persons.

Researcher receives NIH grants to uncover connection between brain development and autism

(Case Western Reserve University) Tony Wynshaw-Boris, M.D., Ph.D., has received two five-year grants totaling more than $5 million from the National Institute of Mental Health of the NIH to uncover links between abnormal embryonic brain development and autism.

CWRU School of Medicine's Mark Griswold, PhD Elected 2017 Fellow of the National Academy of Inventors

Mark A. Griswold, PhD, a professor in the Department of Radiology at Case Western Reserve University School of Medicine, has been elected to the National Academy of Inventors 2017 Fellows Program, the highest professional distinction accorded to academic inventors.

Space scientist, geologist Farouk El-Baz to receive 2018 Inamori Ethics Prize

(Case Western Reserve University) For his life's work, geologist Farouk El-Baz, a NASA scientist on the Apollo space program's site-selection committee, will receive the 2018 Inamori Ethics Prize from the Inamori International Center for Ethics and Excellence at Case Western Reserve University during a ceremony and academic symposium Sept. 13-14.

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