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Normal tissue BRCA1 methylation associated with risk for high-grade ovarian cancer

(American College of Physicians) Normal tissue BRCA1 methylation is associated with risk for high-grade ovarian cancer and may occur as a prenatal event. These findings are published in Annals of Internal Medicine.

MKSAP: 65-year-old man with chronic kidney disease

Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians. A 65-year-old man is evaluated during a follow-up visit for stage G3b/A3 chronic kidney disease due to diabetic nephropathy. He reports doing well with good baseline exercise tolerance and no shortness of breath. Medical history is also significant for type 2 […]

UC researchers find protein that mediates formation of HER2-driven breast cancer

(University of Cincinnati Academic Health Center) Researchers at the University of Cincinnati College of Medicine have identified for the first time that the estrogen receptor-binding protein MED1 is a critical mediator of HER2-driven breast cancer, identifying it as a potential therapeutic target.

Identical twins can share more than identical genes

(Baylor College of Medicine) Independent of their identical genes, identical twins share an additional level of molecular similarity that influences their biological characteristics.

MKSAP: 25-year-old man is evaluated in follow-up after HIV testing

Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians. A 25-year-old man is evaluated in follow-up after HIV testing. He states he has sex with other men and usually uses condoms. He had a negative HIV test result 1 year ago. He feels well today but reports having a flulike […]

The 10 Biggest Fitness Trends Of 2018

The American College of Sports Medicine's annual survey found the top fitness trends of 2018, according to professionals. Here's what to watch for this year.

Dietary sugar linked to increasing bacterial epidemics

(Baylor College of Medicine) The increasing frequency and severity of healthcare-associated outbreaks caused by bacterium Clostridium difficile have been linked to the widely used food additive trehalose.

Medical students, 1885

2 weeks agoHumor / odd : TYWKIWDBI

Photo taken at the Women's Medical College of Philadelphia, now known as Drexel College of Medicine.Photo via the OldSchoolCool subreddit (sepia removed and cropped for size).

MKSAP: 64-year-old man with diabetes

Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians. A 64-year-old man is evaluated for his quarterly diabetes care follow-up visit. Point-of-care HbA1c level is not at goal for...Show More Summary

Introducing internet-based testing for STIs doubles testing uptake in South London boroughs

The randomised controlled trial of more than 2,000 people in Lambeth and Southwark was led by the London School of Hygiene & Tropical Medicine and King's College London¹, in partnership with SH:24, a digital sexual health service.

Wells Fargo Stagecoach Horse Returns from Splint Bone Fracture for Rose Parade Appearance

The off leader of this four-horse hitch recovered from a fractured splint bone following treatment at the University of Georgia College of Veterinary Medicine and will be leading the first six-horse hitch to pull the Wells Fargo Stagecoach in the 2018 Rose Bowl Parade in Pasadena, California next weekend. Show More Summary

MKSAP: 63-year-old man with mid-upper back pain

Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians. A 63-year-old man is evaluated for severe mid-upper back pain following a minor fall 1 day ago. He also notes progressive fatigue of 6 months’ duration and a 6.8-kg (15-lb) weight loss. Medical history is notable for an 80-pack-year smoking history, […]

G-quadruplex regulates breast cancer-associated gene

(Baylor College of Medicine) For breast cancer, carrying protein CD44s, instead of CD44v, has a survival advantage. Researchers have now discovered a mechanism by which cells can regulate switching between the two proteins, opening options for the development of novel therapeutic strategies to control cancer growth in the future.

MKSAP: 48-year-old man with knee pain and swelling

Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians. A 48-year-old man is evaluated for a 2-day history of right anterior knee pain and swelling. The pain began suddenly and has increased in intensity. He currently rates his pain as an 8 on a 10-point scale. He has no knee […]

Cedars-Sinai Helps a Future Physician Grow From Cradle to Medical School

Shannon Sullivan, 26, a student at Howard University College of Medicine in Washington D.C., has already co-authored a major study in a prominent neuroscience journal and earned a coveted fellowship. She traces her career ambitions to...Show More Summary

Atoh1, a potential Achilles' heel of Sonic Hedgehog medulloblastoma

(Baylor College of Medicine) Tyrosine 78 in Atoh1 is phosphorylated exclusively in 'tumor-initiating cells' in sonic hedgehog medulloblastoma and reducing the levels of Atoh1 promotes tumor regression in mice and provides a potential future strategy for treating this type of tumor.

Clinicians Who Ignore Nitric Oxide (NO) Function Put Their Patients at Risk

Dr. Nathan Bryan, Baylor College of Medicine and one of the leading experts in nitric oxide biochemistry and physiology said today, "healthcare providers, especially those helping patients with cardiovascular issues and age-related disease, are not using perhaps the most important 'tool' in their 'toolbox,' restoring nitric oxide function. Show More Summary

Pediatric immunologist Jordan S. Orange recognized for healing through research

(The Academy of Medicine, Engineering & Science of Texas) Jordan Scott Orange, M.D., Ph.D., of Baylor College of Medicine is the recipient of the 2018 Edith and Peter O'Donnell Award in Medicine from The Academy of Medicine, Engineering and Science of Texas (TAMEST).

Typhoid fever toxin has a sweet tooth

(Cornell University) Although the insidious bacterium Salmonella typhi has been around for centuries, very little is actually known about its molecular mechanisms. A new study from researchers at the College of Veterinary Medicine addresses this knowledge gap and may lead to novel, targeted treatments.

ACP calls for elimination of physician compensation disparities

(American College of Physicians) In a new position statement on Compensation Equity and Transparency in the Field of Medicine, the American College of Physicians (ACP) asserts that physicians should receive equitable compensation based on comparable work and compensation should not vary based on characteristics of personal identity.

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