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Novel precision medicine trial for metastatic pancreatic cancer

(Columbia University Medical Center) The Lustgarten Foundation has awarded Columbia University's Herbert Irving Comprehensive Cancer Center (HICCC) a three-year grant, as part of its Translational Clinical Program, to test a new precision medicine approach to the treatment of metastatic pancreatic cancer.

From a novel support group to a book, learning from seven widowed fathers

(UNC Lineberger Comprehensive Cancer Center) UNC Lineberger Comprehensive Cancer Center's Donald Rosenstein, MD, and Justin Yopp, PhD, have published 'The Group: Seven Widowed Fathers Reimagine Life,' which tells the story of personal...Show More Summary

UNC Lineberger awarded $11.9M grant to study radiation treatments for prostate cancer

(UNC Lineberger Comprehensive Cancer Center) The Patient-Centered Outcomes Research Institute has awarded UNC Lineberger Comprehensive Cancer Center's Ronald C. Chen, MD, MPH, a five-year, nearly $12 million grant to fund a comparative study of intensity-modulated radiation therapy and proton beam for prostate cancer.

Researchers Repurpose Immune-Activating Cytokine to Fight Breast Cancer

The most lethal form of breast cancer could have a new treatment option, according to new research out of the Case Comprehensive Cancer Center at Case Western Reserve University School of Medicine. In the Proceedings of the NationalShow More Summary

Researchers repurpose immune-activating cytokine to fight breast cancer

(Case Western Reserve University) The most lethal form of breast cancer could have a new treatment option, according to new research out of the Case Comprehensive Cancer Center. In PNAS, researchers showed triple-negative breast cancer cells are highly vulnerable to interferon-? -- a potent antimicrobial that also activates the immune system. Show More Summary

How Defeating THOR Could Bring a Hammer Down on Cancer

Researchers at the University of Michigan Comprehensive Cancer Center uncovered a novel gene they named THOR. It's a long non-coding RNA that plays a role in cancer development. Knocking it out can halt the growth of tumors.

How defeating THOR could bring a hammer down on cancer

(Michigan Medicine - University of Michigan) Researchers at the University of Michigan Comprehensive Cancer Center uncovered a novel gene they named THOR. It's a highly conserved long non-coding RNA that plays a role in cancer development. Knocking it out can halt the growth of tumors.

National Academy of Inventors and University of New Mexico Comprehensive Cancer Center announce 2017 NAI Fellows

Dr. Cheryl L. Willman of the University of New Mexico Comprehensive Cancer Center has been named a Fellow of the National Academy of Inventors (NAI).

Skin cancer treatment selfie goes viral, has public health lessons

(UNC Lineberger Comprehensive Cancer Center) In a new study, researchers analyzed the impact of one viral social media post in generating awareness about skin cancer.

Immunotherapy strategy could be beneficial for relapsed acute myeloid leukemia

ATLANTA - University of North Carolina Lineberger Comprehensive Cancer Center researchers report that pairing an immunotherapy drug with chemotherapy proved beneficial for some patients with acute myeloid leukemia whose disease did not respond to standard treatment or had relapsed.

Using software, researchers predict tumor markers that could be immune targets

(UNC Lineberger Comprehensive Cancer Center) Researchers report at the 59th Annual American Society for Hematology Annual Meeting in Atlanta on Saturday, Dec. 9, that they were able to validate their approach for predicting markers - called minor histocompatibility antigens - in a group of patients with blood cancers.

Immunotherapy strategy could be beneficial for relapsed acute myeloid leukemia

(UNC Lineberger Comprehensive Cancer Center) UNC Lineberger Comprehensive Cancer Center researchers will present preliminary results from an ongoing phase II trial of chemotherapy and pembrolizumab in relapsed or refractory acute myeloid leukemia at the 59th American Society of Hematology Annual Meeting in Atlanta on Saturday, Dec. 9.

Biological factors don't fully explain racial disparities for breast cancer type

(UNC Lineberger Comprehensive Cancer Center) The biological features of patients' tumors partially explained a racial disparity for women with hormone receptor-positive, HER2-negative breast cancer, but UNC Lineberger Comprehensive Cancer Center researchers said it didn't explain it completely. Show More Summary

Study Uses Genetic Testing to Personalize Treatment for Deadly Blood Cancer

A clinical trial using genetic testing to match acute myeloid leukemia (AML) patients with new therapies is now open at the University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center (UMGCCC). The center is one of seven cancer centers nationwide participating in the Beat AML(r) Master Trial, sponsored by the Leukemia & Lymphoma Society (LLS).

National Experts Map Out Adolescent and Young Adult (AYA) Cancer Research Agenda

Researchers at the Case Comprehensive Cancer Center at Case Western Reserve University School of Medicine, are focusing their efforts on adolescent and young adult (AYA) cancer research. More than 50 leaders from top cancer research institutions will gather this Friday, December 8, in Atlanta to identify a strategic plan for combating AYA cancer for the next three to five years.

Nat'l experts map out AYA cancer Rresearch agenda

(Case Western Reserve University) Researchers at the Case Comprehensive Cancer Center at Case Western Reserve University School of Medicine, are focusing their efforts on adolescent and young adult (AYA) cancer research. More than 50...Show More Summary

New test provides accurate measure of DNA damage from chemical compounds

A new biomarker test developed by researchers at Georgetown Lombardi Comprehensive Cancer Center and their colleagues can help predict, with up to 90 percent certainty, which chemical compounds can cause DNA damage that could lead to cancer. The study was published early online the week of December 4, 2017, in PNAS.

New test provides accurate measure of DNA damage from chemical compounds

(Georgetown University Medical Center) A new biomarker test developed by researchers at Georgetown Lombardi Comprehensive Cancer Center and their colleagues can help predict, with up to 90 percent certainty, which chemical compounds can cause DNA damage that could lead to cancer.

The Leukemia & Lymphoma Society awards grant to Savoldo for immunotherapy research

(UNC Lineberger Comprehensive Cancer Center) A grant from The Leukemia & Lymphoma Society will help fund clinical research led by UNC Lineberger's Barbara Savoldo, MD, PhD, into an investigational chimeric antigen receptor (CAR) T-cell treatment for acute lymphoblastic leukemia that would include a built-in 'safety switch.'

Study reveals new mechanism used by cancer cells to disarm attacking immune cells

(Ohio State University Wexner Medical Center) A new study by researchers at The Ohio State University Comprehensive Cancer Center -- James Cancer Hospital and Solove Research Institute identifies a substance released by pancreatic cancer cells that protects them from attack by immune cells called macrophages.

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