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Chory and Walter awarded breakthrough prizes

(Howard Hughes Medical Institute) HHMI Investigators Joanne Chory and Peter Walter are among five scientists honored for transformative advances toward understanding living systems and extending human life.

New silicon probes record activity of hundreds of neurons simultaneously

(Howard Hughes Medical Institute) Neuroscientists who want to follow the nervous system's cellular conversations will soon have access to easy-to-use technology that simultaneously monitors neural activity at hundreds of different sites within the brain.

Electron microscopy uncovers unexpected connections in fruit fly brain

(Howard Hughes Medical Institute) Janelia scientists have used a powerful microscopy technique to discover new connections in the memory and learning center of the Drosophila brain.

Mini-microscopes reveal brain circuitry behind social behavior

(Howard Hughes Medical Institute) A microscope lens implanted deep inside a mouse's brain shows different patterns of neural activity when the mouse interacts with males, females, or other stimuli. Now, researchers have discovered that sexual experience can trigger long-term changes in these brain patterns.

300 neurons traced in extensive brain wiring map

(Howard Hughes Medical Institute) A vast effort by a team of Janelia Research Campus scientists is rapidly increasing the number of fully-traced neurons in the mouse brain. Researchers everywhere can now browse and download the 3-D data.

Whole genome sequencing identifies new genetic signature for autism

(Howard Hughes Medical Institute) An analysis of the complete genomes of 2,064 people reveals that multiple genetic variations could contribute to autism. The work suggests that scanning whole genomes may one day be useful for clinical diagnostics.

Rosbash awarded 2017 Nobel Prize in Physiology or Medicine

(Howard Hughes Medical Institute) The Nobel Assembly at the Karolinska Institute announced today that Michael Rosbash, a Howard Hughes Medical Institute (HHMI) investigator at Brandeis University, Jeffrey C. Hall of Brandeis University and Michael W. Show More Summary

New role for fragile X protein could offer clues for treatment

(Howard Hughes Medical Institute) The protein behind fragile X syndrome, a leading cause of autism and intellectual disability, controls a suite of genetic regulators.

3-D protein structure offers insight into rapid communication by brain cells

(Howard Hughes Medical Institute) New HHMI research reveals how three proteins help brain cells synchronize the release of chemical signals. A similar interaction may play a role in how cells secrete insulin and airway mucus, too.

New fluorescent dyes could advance biological imaging

(Howard Hughes Medical Institute) Scientists at HHMI's Janelia Research Campus have developed a new method for fine-tuning the structure of rhodamine dyes, and can now create a colorful palette of fluorescent molecules.

Expanding access to new tools to study childhood cancers

Howard Hughes Medical Institute (HHMI) scientists have created an extensive resource for studying pediatric cancers, which they are sharing widely to help accelerate research.

Expanding access to new tools to study childhood cancers

(Howard Hughes Medical Institute) HHMI Investigator Michael Dyer and colleagues are widely sharing data and samples from nearly 100 new tumor models representing 12 pediatric cancers.

Origins of DNA folding suggested in archaea

(Howard Hughes Medical Institute) Proteins in archaea bend strands of DNA in a way that's similar in eukaryotes, new research from HHMI investigator and colleagues reveals. That similarity hints at the evolutionary origin of the elaborate folding that eukaryotic cells use to cram their genome into a nucleus.

Rewired taste system reveals how flavors move from tongue to brain

(Howard Hughes Medical Institute) By creating mice with mixed-up taste sensors, HHMI Investigator Charles Zuker and colleagues show how the taste system continually remakes itself.

The first civilizations of Greece are revealing their stories to science

(Howard Hughes Medical Institute) A new analysis of genome sequences from the ancient Minoans and Mycenaeans by HHMI investigator and colleagues offers insight into the origins of these Bronze Age cultures.

Study identifies enzyme that protects cells from toxic fat

A new study from Harvard T.H. Chan School of Public Health and Howard Hughes Medical Institute sheds light on how a key fat-producing enzyme helps protect cells from a toxic form of fat.

Artificial intelligence helps build brain atlas of fly behavior

(Howard Hughes Medical Institute) Scientists at HHMI's Janelia Research Campus created comprehensive brain maps linking different groups of neurons to specific behaviors, using a machine-learning program that annotated more than 225 days of videos of flies -- a feat that would have taken humans some 3,800 years.

24 schools commit to diversity and inclusion through HHMI Inclusive Excellence initiative

(Howard Hughes Medical Institute) HHMI has selected 24 schools in the first round of the Inclusive Excellence initiative, a program that aims to help increase the capacity of colleges and universities to effectively engage all students so that they can be successful in science, especially undergraduates who enter four-year institutions via nontraditional pathways.

Tufts University awarded $1 million grant to boost diversity in natural sciences

(Tufts University) A group of faculty at Tufts University's School of Arts and Sciences has received a $1 million grant from the Howard Hughes Medical Institute (HHMI) to broaden participation and cultivate the talents of undergraduate students of diverse backgrounds in the natural sciences.

Engineers genetically modified a dragonfly to carry a tiny solar-powered backpack

Researchers at Charles Stark Draper Laboratory and Howard Hughes Medical Institute have created a tiny insect drone. A dragonfly was genetically modified so that that it can be piloted remotely through pulses in its nerve cord. It carries a small backpack with electronics and a solar panel that powers it. But this isn't the first animal cyborg. Show More Summary

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