Trend Results : Howard Hughes Medical Institute

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Mosquito brain atlas aims to reveal neural circuitry of behavior

(Howard Hughes Medical Institute) HHMI researchers have built, the first map of the female mosquito brain. The new resource may ultimately uncover the circuitry behind biting and other behaviors.

Ancient DNA tells tales of humans' migrant history

(Howard Hughes Medical Institute) Fueled by advances in analyzing DNA from the bones of ancient humans, scientists have dramatically expanded the number of samples studied -- revealing vast and surprising migrations and genetic mixing of populations in our prehistoric past.

CRISPR-based technology can detect viral DNA

(Howard Hughes Medical Institute) Technology that's been used to edit genomes can also spot snippets of DNA. Such detective work may enable rapid, reliable ways to identify infections and cancer.

Clues to aging found in stem cells' genomes

(Howard Hughes Medical Institute) In fruit flies, repeating genetic elements shrink with age, but then expand in future generations, a resurgence that may help explain how some cells stay immortal.

Time to publish peer referee comments?

A meeting at the Howard Hughes Medical Institute last week asked whether journals should start publishing the reviews they receive on papers. As reported by Jeffrey Brainard in Science, the consensus was yes: “Researchers debate whether...Show More Summary

How Zika infection drives fetal demise

(Howard Hughes Medical Institute) An interferon cell receptor spurs cell suicide in fetuses infected with the Zika virus and could play a role in certain pregnancy complications.

Hunting for immune cells' cancer targets

(Howard Hughes Medical Institute) A method developed by HHMI investigators sifts through hundreds of millions of potential targets to find a precise cancer beacon. The results may lead to better immunotherapies, which harness the immune system to attack tumors.

CRISPR treatment prevents hearing loss in mice

(Howard Hughes Medical Institute) A single treatment of a genome editing agent partially preserved hearing in mice with genetic deafness. The work could one day help scientists treat certain forms of genetic hearing loss in humans.

Chory and Walter awarded breakthrough prizes

(Howard Hughes Medical Institute) HHMI Investigators Joanne Chory and Peter Walter are among five scientists honored for transformative advances toward understanding living systems and extending human life.

New silicon probes record activity of hundreds of neurons simultaneously

(Howard Hughes Medical Institute) Neuroscientists who want to follow the nervous system's cellular conversations will soon have access to easy-to-use technology that simultaneously monitors neural activity at hundreds of different sites within the brain.

Electron microscopy uncovers unexpected connections in fruit fly brain

(Howard Hughes Medical Institute) Janelia scientists have used a powerful microscopy technique to discover new connections in the memory and learning center of the Drosophila brain.

Mini-microscopes reveal brain circuitry behind social behavior

(Howard Hughes Medical Institute) A microscope lens implanted deep inside a mouse's brain shows different patterns of neural activity when the mouse interacts with males, females, or other stimuli. Now, researchers have discovered that sexual experience can trigger long-term changes in these brain patterns.

300 neurons traced in extensive brain wiring map

(Howard Hughes Medical Institute) A vast effort by a team of Janelia Research Campus scientists is rapidly increasing the number of fully-traced neurons in the mouse brain. Researchers everywhere can now browse and download the 3-D data.

Whole genome sequencing identifies new genetic signature for autism

(Howard Hughes Medical Institute) An analysis of the complete genomes of 2,064 people reveals that multiple genetic variations could contribute to autism. The work suggests that scanning whole genomes may one day be useful for clinical diagnostics.

Rosbash awarded 2017 Nobel Prize in Physiology or Medicine

(Howard Hughes Medical Institute) The Nobel Assembly at the Karolinska Institute announced today that Michael Rosbash, a Howard Hughes Medical Institute (HHMI) investigator at Brandeis University, Jeffrey C. Hall of Brandeis University and Michael W. Show More Summary

New role for fragile X protein could offer clues for treatment

(Howard Hughes Medical Institute) The protein behind fragile X syndrome, a leading cause of autism and intellectual disability, controls a suite of genetic regulators.

3-D protein structure offers insight into rapid communication by brain cells

(Howard Hughes Medical Institute) New HHMI research reveals how three proteins help brain cells synchronize the release of chemical signals. A similar interaction may play a role in how cells secrete insulin and airway mucus, too.

New fluorescent dyes could advance biological imaging

(Howard Hughes Medical Institute) Scientists at HHMI's Janelia Research Campus have developed a new method for fine-tuning the structure of rhodamine dyes, and can now create a colorful palette of fluorescent molecules.

Expanding access to new tools to study childhood cancers

Howard Hughes Medical Institute (HHMI) scientists have created an extensive resource for studying pediatric cancers, which they are sharing widely to help accelerate research.

Expanding access to new tools to study childhood cancers

(Howard Hughes Medical Institute) HHMI Investigator Michael Dyer and colleagues are widely sharing data and samples from nearly 100 new tumor models representing 12 pediatric cancers.

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