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US hospitals testing experimental therapies to prevent two common bacterial infections

(NIH/National Institute of Allergy and Infectious Diseases) NIAID-supported clinical sites in the US are participating in two ongoing international Phase 2 trials evaluating investigational antibody-based therapies aimed at preventing potentially antibiotic-resistant infections. Show More Summary

Immune Signature Predicts Asthma Susceptibility

Asthma is a chronic inflammatory disease driven by the interplay of genetics, environmental factors and a diverse cast of immune cells. In their latest study, researchers at La Jolla Institute for Allergy and Immunology (LJI) identified a subset of T cells, whose frequency serves as early childhood immune signature that predicts the risk of developing asthma later on.

Immune signature predicts asthma susceptibility

(La Jolla Institute for Allergy and Immunology) Asthma is a chronic inflammatory disease driven by the interplay of genetics, environmental factors and a diverse cast of immune cells. In their latest study, researchers at La Jolla Institute...Show More Summary

NIH study will assess biomarker as indicator of viral lower respiratory tract infection

(NIH/National Institute of Allergy and Infectious Diseases) A new clinical trial sponsored by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, aims to determine whether low...Show More Summary

NIH scientists adapt new brain disease test for Parkinson's, dementia with Lewy bodies

(NIH/National Institute of Allergy and Infectious Diseases) NIH scientists have modified a test for early diagnosis of prion diseases with the goal of improving early diagnosis of Parkinson's disease and dementia with Lewy bodies. The...Show More Summary

Ebola virus infects reproductive organs in monkeys

(NIH/National Institute of Allergy and Infectious Diseases) Ebola virus can infect reproductive organs of male and female macaques, according to a new study, suggesting humans could be similarly infected. Prior studies have revealed sexual transmission of Ebola virus, and viral RNA persisting in semen following recovery. Show More Summary

New research suggests your immune system can protect against MRSA infections

(Johns Hopkins Medicine) After years of investigation, researchers at Johns Hopkins, the University of California, Davis, and the National Institute of Allergy and Infectious Diseases have discovered how the immune system might protect a person from recurrent bacterial skin infections caused by Staphylococcus aureus (staph).

15 years later, PEPFAR continues to save lives

Experts from the National Institute of Allergy and Infectious Diseases have authored a perspective recognizing the United States President's Emergency Plan for AIDS Relief (PEPFAR) for 15 years of implementing an innovative program to prevent, treat, and care for persons living with HIV and AIDS.

15 years later, PEPFAR continues to save lives

(NIH/National Institute of Allergy and Infectious Diseases) Experts from the National Institute of Allergy and Infectious Diseases have penned a NEJM perspective recognizing the United States President's Emergency Plan for AIDS Relief...Show More Summary

Study links gut-homing protein levels with HIV infection risk, disease progression

(NIH/National Institute of Allergy and Infectious Diseases) For the first time, scientists have shown a relationship between the proportion of key immune cells that display high levels of a gut-homing protein called alpha-4 beta-7 at the time of HIV infection and health outcomes. Previous research illustrated this relationship in monkeys infected with a simian form of HIV.

NIH begins large HIV treatment study in pregnant women

(NIH/National Institute of Allergy and Infectious Diseases) NIH has launched a large international study to compare the safety and efficacy of three antiretroviral treatment regimens for pregnant women living with HIV and the safety of these regimens for their infants. Show More Summary

Flu infection study increases understanding of natural immunity

(NIH/National Institute of Allergy and Infectious Diseases) People with higher levels of antibodies against the stem portion of the influenza virus hemagglutinin (HA) protein have less viral shedding when they get the flu, but don't have fewer or less severe signs of illness, according to a new study. Show More Summary

America hit hard by 2017-2018 flu season

last monthHumor / odd : The Sideshow

Dr. Fauci of the National Institute of Allergy and Infectious Diseases shares insight.

NIH scientists find microbes on the skin of mice promote tissue healing, immunity

(NIH/National Institute of Allergy and Infectious Diseases) Beneficial bacteria on the skin of lab mice work with the animals' immune systems to defend against disease-causing microbes and accelerate wound healing, according to new research...Show More Summary

LJI researchers discover key driver of atopic dermatitis

(La Jolla Institute for Allergy and Immunology) Severe eczema, also known as atopic dermatitis, is a chronic inflammatory skin condition that is driven by an allergic reaction. In their latest study, researchers at La Jolla Institute reveal an important player that promotes skin inflammation in atopic dermatitis and the characteristic thickening of the skin.

NIH study supports use of short-term HIV treatment interruption in clinical trials

(NIH/National Institute of Allergy and Infectious Diseases) A short-term pause in HIV treatment during a carefully monitored clinical trial does not lead to lasting expansion of the HIV reservoir nor cause irreversible damage to the immune system, new findings suggest.

MERS antibodies produced in cattle safe, treatment well tolerated in phase 1 trial

(NIH/National Institute of Allergy and Infectious Diseases) An experimental treatment developed from cattle plasma for Middle East respiratory syndrome (MERS) coronavirus infection shows broad potential, according to a small clinical trial led by National Institutes of Health scientists and their colleagues. Show More Summary

Zika remains a research and public health challenge, say NIAID scientists

(NIH/National Institute of Allergy and Infectious Diseases) The Zika virus has become established in more than 80 countries, infected millions of people, and left many babies with birth defects. Although scientists have made progress...Show More Summary

Omalizumab improves efficacy of oral immunotherapy for multiple food allergies

(NIH/National Institute of Allergy and Infectious Diseases) Combining a 16-week initial course of the medication omalizumab with oral immunotherapy (OIT) greatly improves the efficacy of OIT for children with allergies to multiple foods, new clinical trial findings show. Show More Summary

San Diego Team Wins $ 6.9 Million Grant to Establish PrecISE Network Clinical Center

A team of physicians, scientists and biostatisticians from La Jolla Institute for Allergy and Immunology and UC San Diego School of Medicine joined forces across institutions to successfully compete for an $6.9 million grant to establish one of only 10 PrecISE Network Clinical Centers nationwide.

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