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Case Western Reserve University Receives NIH Funding to Participate in Launch of Genomics Center on Alzheimer's Disease

Case Western Reserve University School of Medicine is one of six recipients of a five-year, $10.8 million award from the National Institute on Aging, part of the National Institutes of Health, to establish the Coordinating Center for Genetics and Genomics of Alzheimer's disease.

Penn Medicine Team and Collaborators Receive NIH Award to Launch Genomics Center on Alzheimer's Disease

A five-year, projected $10.8 million award from the National Institute on Aging will establish the Coordinating Center for Genetics and Genomics of Alzheimer's Disease, a joint venture of researchers from the Perelman School of Medicine at the University of Pennsylvania and five other institutions.

National Institutes of Health Chooses Mayo Clinic for Biobank, but what is a Biobank?

ROCHESTER, Minn. — On May 26, the National Institutes of Health (NIH) awarded Mayo Clinic $142 million over five years to serve as home for the 1-million-person Precision Medicine Initiative® (PMI) biobank. Precision Medicine Defined: Precision, or personalized medicine, is a model of care that customizes medical treatment to each individual. To illuminate differences and […]

Time to Put a Stop to Workplace Bullying

By RONALD WYATT, MD Civility is a system value that improves safety in health care settings. The link between civility, workplace safety and patient care is not a new concept. The 2004 Institute of Medicine report, “Keeping Patients Safe: Transforming the Work Environment of Nurses,” emphasizes the importance of the work environment in which nurses

The Truth About Your Vitamins And Supplements

Nutritional supplements are big business. It’s estimated that 64% of people use medicinal plants for therapeutic purposes. According to the National Institutes of Health, U.S. sales of dietary supplements reached $36.7 billion in 2014.[1] The herbal medicine market is worth $60 billion globally and growing fast. Show More Summary

ClinicalTrials.gov vs. Drugs@FDA: A comparison of results reporting for new drug trials

Pharmaceutical companies and other sponsors of clinical drug trials are required to report results to ClinicalTrials.gov, a registry run by the U.S. National Library of Medicine (NLM) at the National Institutes of Health (NIH). It's the largest clinical trials database, currently holding registrations from about 200,000 trials. read more

New TSRI method opens door to development of many new medicines

LA JOLLA, CA--June 15, 2016--Scientists at The Scripps Research Institute (TSRI) have developed a powerful new method for finding drug candidates that bind to specific proteins. read more

Foundation Medicine wants to find 'software bugs' in your genome to fight cancer

What won Alexis Borisy over was the idea of software bugs. Borisy, now a partner at Third Rock Ventures, along with four scientists affiliated with MIT and Harvard's Broad Institute who were leaders in cancer genomics got started back in 2008 working on what would soon become Foundation Medicine (No. Show More Summary

New TSRI Method Opens Door to Development of Many New Medicines

Scientists at The Scripps Research Institute have developed a powerful new method for finding drug candidates that bind to specific proteins, an advance that can be applied to a large set of proteins at once, even to the thousands of distinct proteins directly in their native cellular environment.

Mouse model shows that Notch activation can drive metastatic prostate cancer

HOUSTON - (June 13, 2016) - Notch signaling is involved in prostate cancer and, in a paper published today in The Journal of Clinical Investigation, researchers from Baylor College of Medicine and other institutions have shown that, in a mouse model of the disease, Notch promotes metastasis, or the ability of the tumors to spread to other organs. read more

MS Cure: Immune System Replacement Reverses Devastating Disease, Offers Hope To Millions

This week, scientists at the Ottawa Hospital Research Institute announced that they have finally discovered a cure for MS. Dr. Harold Atkins is Medical Director of the Regenerative Medicine Program at the Ottawa Hospital Research Institute, and he is convinced that a treatment called IAHSCT can now be used to treat people whose lives have... Show More Summary

New Institute for Diabetes and Metabolic Health Debuts at UC San Diego

The University of California San Diego School of Medicine has launched the Institute for Diabetes and Metabolic Health (IDMH), a new cross-disciplinary, collaborative effort to address one of the nation's leading public health threa...

New antiviral drugs could come from DNA 'scrunching'

PHILADELPHIA - Evidence of DNA "scrunching" may one day lead to a new class of drugs against viruses, according to a research team from the Perelman School of Medicine at the University of Pennsylvania, the Georgia Institute of Technology, and Columbia University. Show More Summary

PLOS Medicine Podcast episode 1: The Actionable Cancer Genome

PLOS Medicine’s Senior Research Editor Clare Garvey interviews Elaine Mardis and Marc Ladanyi, Guest Editors for our Special Issue on the Actionable Cancer Genome   Elaine Mardis is co-Director of the McDonnell Genome Institute and Robert E. and

UCLA, Cleveland Clinic and UCSD Collaboration Demonstrates Potential Treatment Breakthrough for Advanced Brain Cancer

Doctors at UCLA, Cleveland Clinic, University of California San Diego School of Medicine and additional institutions have achieved a milestone in development of a treatment for people with recurrent glioblastoma, the most common and aggressive form of brain cancer, by successfully demonstrating a modified virus that can extend the lives of patients with recurrent glioblastoma.

Hunting for Huntington’s Disease Treatments in the New Millennium

Karen Ring, of the California Institute for Regenerative Medicine, gives an update from the HD CARE symposium at UC Irvine. “Over the next five to ten years, we want to make Huntington’s disease an increasingly

Prevention of Genetic Breast Cancer Within Reach

An international team led by researchers at the Austrian Institute of Molecular Biotechnology (IMBA) in Vienna and the University of Maryland School of Medicine in Baltimore discovered that genetically determined breast cancer can be largely prevented by blocking a bone gene. Show More Summary

What You Need to Know About Clock Genes and Your Health

I recently attended the Institute for Functional Medicine's annual conference. Dr. Jeffrey Bland gave a fascinating overview of the most recent research on clock genes. These are a variety of genes in our bodies (and in most living things) that regulate life functions. Show More Summary

NIH Awards Mayo Clinic $145M to Create Biobank for Precision Medicine Initiative

The National Institutes of Health (NIH) has awarded Mayo Clinic $142 million over five years as part of President Obama’s Precision Medicine Initiative to create the world’s largest biobank for the PMI Cohort Program. Mayo Clinic will...Show More Summary

Mayo Clinic to be Home of National Precision Medicine Initiative (PMI) Cohort Program Biobank

ROCHESTER, Minn. — Mayo Clinic will be awarded $142 million in funding over five years by the National Institutes of Health (NIH) to serve as the national Precision Medicine Initiative (PMI) Cohort Program biobank. The biobank will hold a research repository of biologic samples, known as biospecimens, for this longitudinal program that aims to enroll 1 […]

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