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Reading between the genes

For a long time dismissed as 'junk DNA,' we now know that also the regions between the genes fulfill vital functions. Scientists have now developed a method to find regulatory DNA regions which are active and controlling genes.

Shedding light on the 'dark matter' of the genome

What used to be dismissed by many as 'junk DNA' is back with a vengeance as growing data points to the importance of non-coding RNAs (ncRNAs) -- genome's messages that do not code for proteins -- in development and disease. Researchers have developed a method that enables scientists to explore in depth what ncRNAs do in human cells.

Key gene in development of celiac disease has been found in 'junk' DNA

40% of the population carry the main risk factor for celiac disease but only 1% develop the disease. A newly found gene that influences its development has been found in what until recently has been known as ‘junkDNA. Celiac disease...Show More Summary

A key gene in the development of celiac disease has been found in 'junk' DNA

Coeliac disease is a chronic, immunological disease that is manifested as intolerance to gluten proteins present in wheat, rye and barley. This intolerance leads to an inflammatory reaction in the small intestine that hampers the absorption of nutrients. The only treatment is a strict, life-long, gluten-free diet. read more

'Junk' DNA plays role in preventing breast cancer

Supposed 'junk' DNA, found in between genes, plays a role in suppressing cancer, according to new research. The human genome contains around three meters of DNA, of which only about two per cent contains genes that code for proteins. Since the sequencing of the complete human genome in 2000, scientists have puzzled over the role of the remaining 98 per cent.

'Junk' DNA plays role in preventing breast cancer

Supposed "junk" DNA, found in between genes, plays a role in suppressing cancer, according to new research by Universities of Bath and Cambridge. The human genome contains around three metres of DNA, of which only about two per cent contains genes that code for proteins. Show More Summary

Matter: Telling Jewels From Junk in DNA

5 months agoHealth : NYTimes: Health

Some cellular DNA yields molecules that serve mysterious but important functions in the cell, new research suggests.

Not 'junk' anymore: Obscure DNA has key role in stroke damage

MADISON, Wis. -- A study of rats released today shows that blocking a type of RNA produced by what used to be called "junk DNA" can prevent a significant portion of the neural destruction that follows a stroke. The research points toward...Show More Summary

Defendant in Zion double murder accuses young victim's dad

The defense attorney for Jorge Torrez, accused of the 2005 murder of two young girls in Zion, said in court Tuesday that the state's DNA evidence is "junk," and he will argue at trial that Jerry Hobbs, who initially confessed to the murders but was later exonerated, is the likely killer. "Our defense...

Junk DNA: How much of our genetic material pulls its weight?

Science can’t decide if our genes have more or less value than the Baldwin brothers The post Junk DNA: How much of our genetic material pulls its weight? appeared first on Macleans.ca.

Junk DNA must be…fractal ballast!

I’ve now read two novel attempts to explain the existence of junk DNA. To a lot of people, the very idea of junk DNA is offensive: whatever process built us, whether divine fiat or the razor-sharp honing of natural selection, must be powerful, omnipotent or nearly so, and incapable of tolerating any noise or sloppiness,…

Three reasons why nobody should be surprised by junk DNA

Science writer Carl Zimmer just wrote an article in the New York Times about the junk DNA wars and it's worth a read. Zimmer presents conflicting expert opinions about the definition of 'junk' and the exact role that junk DNA plays in various genetic processes. Show More Summary

The Junk DNA Fight

From yesterday's New York Times Magazine, here's an excellent intro by Carl Zimmer to the Junk DNA Wars. In January, Francis Collins, the director of the National Institutes of Health, made a comment that revealed just how far the consensus has moved. Show More Summary

Man Unable Or Possibly Just Unwilling To Justify Majority Of Self

“Over millions of years, essential genes haven’t changed very much, while junk DNA has picked up many harmless mutations. Scientists at the University of Oxford have measured evolutionary change over the past 100 million years at every spot in the human genome. ‘I can today say, hand on my heart, that 8 percent, plus or […]

Cancer risk linked to DNA 'wormholes'

Single-letter genetic variations within parts of the genome once dismissed as 'junk DNA' can increase cancer risk through wormhole-like effects on far-off genes, new research shows. Researchers found that DNA sequences within 'gene deserts'...Show More Summary

JunkDNA’ from million-year-old viruses actually have vital role in human intelligence: study

last yearNews : The Raw Story

A study released today by researchers at Lund University in Sweden indicates that inherited viruses may be responsible for creating the complex neural networks that make up the human brain. For many years, the endogenous retroviruses that comprise about 5 percent of human DNA were thought to be...

No junk: Long RNA mimics DNA, restrains hormone responses

It arises from what scientists previously described as "junk DNA" or "the dark matter of the genome," but this gene is definitely not junk. The gene GAS5 acts as a brake on steroid hormone receptors, making it a key player in diseases such as hormone-sensitive prostate and breast cancer. read more

Splitting the Junk DNA Difference

A big dispute erupted in the genomics world in 2012 with the publication of the ENCODE consortium's data - and with their interpretation of it. How much of the human genome is functional? And just what does "functional" mean? The ENCODE...Show More Summary

Penn Team Finds Ovarian Cancer Oncogene in "Junk DNA"

A team has mined genomic sequences sequences to identify a non-protein-coding RNA whose expression is linked to ovarian cancer.

Penn team finds ovarian cancer oncogene in 'junk DNA'

PHILADELPHIA - Over the years researchers have made tremendous strides in the understanding and treatment of cancer by searching genomes for links between genetic alterations and disease. read more

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