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Liver ATF4 Upregulation Common to Many of the Reliable Means of Slowing Aging in Mice

4 hours agoHealth / Aging : Fight Aging

There are a score or more ways to reliably slow aging in mice, methods that include a few classes of drug, various single gene alterations, and calorie restriction. The most exceptional of these methods extends life by 60% or so, but most are in the much more modest 10-20% range at best. Show More Summary

This Week in Tabloids: Everyone is PREGNANT and/or DUMPED

Welcome back to Midweek Madness, in which in which we we struggle vainly to make meaning of the vast abyss contained within the pages of Star, Us Weekly, OK!, Life & Style and InTouch. This week: BEYONCÉ PREGNANT, MARIAH DUMPED, and KIM both PREGNANT & DUMPED. Read more...

Puppies Playing with their Mothers: A Compilation

7 hours agoOdd : Neatorama

YouTube Link Moms teach us so much about what we'll need to know later in life. For a dog, that means a ton of carefree playtime. This compilation video features dog mothers of various breeds playing with their young offspring and seemingly having a grand time doing so. Via Tastefully Offensive.

The Real Meaning Of Life Begins When You Find A Cause

NBA and college basketball great Jimmy Walker once said to me, "Ray, you were one of the best outside shooters in college basketball and the highest vote getter in Boston history, when you were Mayor of Boston, so now that you are out...Show More Summary

When So-called Experts Say Don’t Do a Business Plan…

… don’t be confused. What they really mean is …  Don’t do a long static formal business plan. Do a lean, just-big-enough business plan. Deal with it as a constantly-renewing latest version, with a shelf life of a few weeks at most. Don’t fill it with excess supporting information. They won’t even look at a...

Lifetime implies murder in new 'Brittany Murphy Story' trailer

The official cause of actress Brittany Murphy's 2009 death is cardiac arrest, but Lifetime's upcoming movie about her life suggests she may have died by a more sinister means. In the new trailer for "The Brittany Murphy Story," the belated...Show More Summary

Animal Planet Is Giving a Whole New Meaning to 'Labor Day'

If you have nothing to do over Labor Day, why not turn on your computer and spend it watching THE MIRACLE OF LIFE? All holiday weekend, Animal Planet will be showing a live feed on its website of various species giving birth and spoiler alert: it will be intense, slimy and have a damn cute ending. Read more...

Disabled Gamer Talks About How Twitch Saved His Life

Ken Worrall plays Diablo, World of Warcraft and Starcraft on Twitch under the name NoHandsKen. It means a whole lot to him, because as a result of an accident 20 years ago, Ken has Tetraplegia. Read more...

30 Crucial Things to Know About Life

Nick Crocker, over at Medium, has spent a great deal of time trying to find the best means of living life and living it well. Here are the top 30 things he believes are crucial to keep in mind at all times. 1. Remember you will die. Maybe even today. Show More Summary

"Much of the time, the law is settled and plain. But life turns up new problems..."

"... and lawyers, officials, and citizens debate the meaning of terms that seemed clear years or even months before. For in the end laws are just words on a page — words that are sometimes malleable, opaque, as dependent on context and...Show More Summary

Water delivery drivers dice with death in war-torn Gaza

Mohammed al-Khatib fears for his life every time he gets behind the wheel. In wartime, providing drinking water to homes and schools in Gaza means dicing with death. At 23, Khatib is a veteran of two previous wars between Hamas and Israel, in 2008 and 2012, but nothing prepared him for the bombings, shredded nerves and death toll this time around. Show More Summary

25 Great, Geektastic School Supplies For All Your Back to School Needs - Apologies for uttering the dreaded "s" word.

5 days agoOdd : Geekosystem

I may do an impromptu glance of complete and utter glee every time I remember I never have to go to school another day in my life, but there's one thing I do miss, and that's school supplies. I mean, yeah, "office supplies" are awesome, and they're basically the same thing, but that just sounds so... Show More Summary

We Say This With All Our Heart

It's been a very challenging week for us. Life can be especially hard at times. But your support and encouragement means sooooo much to us! Thank you! TRULY! From the bottom of our heart! We thank you and appreciate you so much! Big hug to you all! And thank you, also, to our advertisers - they help make this all [...]

People Who Live Near Fixed-Rail Transit Are Happier

6 days agoUnited States / Seattle : Slog

The Atlantic: Jason Cao, a transport policy scholar at the University of Minnesota, has conducted a short but tidy study that demonstrates just what good public transit can mean to a person's life. His findings, in a word: satisfaction. Show More Summary

Keeping Your Corporate Life Successful

6 days agoOdd : Thought Catalog

The other side of wearing branded stilettos; working in a corporate means business.

Microbes Found Beneath Antarctic Ice: What It Means for Alien Life Hunt

The discovery of a complex microbial ecosystem far beneath the Antarctic ice may be exciting, but it doesn't necessarily mean that life teems on frigid worlds throughout the solar system, researchers caution. Scientists announced today (Aug. Show More Summary

Amber Portwood Makes Heartbreaking and Scary Confession

Post by Joanna Mazewski. Just when you thought Amber Portwood was finally back on track with her new life, her latest revelation proves that she has a long road to recovery ahead of her. I mean, it's so bad you can't help but ache for...Show More Summary

Frisky Eats: 11 Ways To Spike Your Lemonade

When life gives you lemons, make alcoholic lemonade, that’s what I say (no wonder I didn’t have one of those roadside lemonade stands as a kid). Anyway, today is National Lemonade Day, which means it’s the perfect time to kick your drink game up a notch. Forget about just adding a simple splash of vodka [...]

The Ivy League, Mental Illness, and the Meaning of Life

William Deresiewicz explains how an elite education can lead to a cycle of grandiosity and depression. 

Meet The Newest Game That Will Take Over Your Life

Now that the 2048 craze is finally dying down and you thought you'd get back to your productive self, a new contender called Hextris has entered the ring. Hextris is a simple reincarnation of Tetris in hexagon form. Meaning that colored...Show More Summary

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