Scientists have devised a novel DNA vaccine approach through molecular design to improve the immune responses elicited against one of the most important cancer antigen targets.
With a background in molecular genetics, the head of iPad Rehab leads a team of mostly women who fix severely damaged iPhones and iPads, even without manufacturer support.
(Massachusetts General Hospital) Massachusetts General Hospital researchers have identified a mechanism that controls the expression of genes regulating the growth of the most aggressive form of medulloblastoma, the most common pediatric brain tumor.
Using her background in molecular genetics, Jessa Jones has pioneered a new form of board-level iPhone repair. She's teaching the world to fix devices that no one, not even Apple, thought it was possible to fix.
Sometimes cells resist medication by spitting it back out. Cancer cells, in particular, have a reputation for defiantly expelling the chemotherapy drugs meant to kill them. Researchers at The Rockefeller University have shed new light on a molecular pump that makes this possible, by determining its three-dimensional structure, down to the level of atoms.
(Rockefeller University) Sometimes cells spit out things we don't want them to--like medications. Researchers have determined the three-dimensional structure of a tiny pump that expels, among other things, chemotherapy agents. This new knowledge could lead to the design of more effective drugs.
(The Wistar Institute) Scientists at The Wistar Institute and Inovio Pharmaceuticals, Inc. have devised a novel DNA vaccine approach through molecular design to improve the immune responses elicited against one of the most important cancer antigen targets.
Sugar can damage cell proteins via glycation. Now, study finds glycation damage in enzyme for immune function and insulin regulation in early Alzheimer's.
You already know that sugar isn't the best thing for your health, but new research out of England might just give you another reason to avoid the white stuff. Scientists there say they've discovered a molecular link between blood sugar...Show More Summary
(Max Delbrück Center for Molecular Medicine in the Helmholtz Association) Small 'bubbles' frequently form on membranes of cells and are taken up into their interior. The process involves EHD proteins -- a focus of research by Prof. Oliver Daumke of the MDC. He and his team have now shed light on how these proteins assemble on the surface of a cell and reshape its membrane.
Fathers who use cocaine at the time of conceiving a child may be putting their sons at risk of learning disabilities and memory loss. The findings of the animal study were published online in Molecular Psychiatry by a team of researchers from the Perelman School of Medicine at the University of Pennsylvania.
(Saint Louis University) In a recent paper, Joel Eissenberg, Ph.D., professor of biochemistry and molecular biology at Saint Louis University, explores questions that stem from new advances in direct-to-consumer DNA tests, which have the effect of separating the physician-patient relationship from access to new personal health data.
(University of Bath) For the first time a molecular 'tipping point' has been demonstrated in Alzheimer's, linking high blood sugar with this debilitating disease
(Molecular Biology and Evolution (Oxford University Press)) New research recently published in the scientific journal, Molecular Biology and Evolution, by a team of scientists from Ireland and India resolved a 195-year old confusionShow More Summary
(Chinese Academy of Sciences Headquarters) A research term led by Prof. ZHANG Donghui from State Key Laboratory of Molecular Reaction Dynamics of Dalian Institute of Chemical Physics has carried out an accurate quantum dynamics study of the H' + CH4 ¡ú CH3H' + H substitution reaction and its isotope analogies. Show More Summary
The CRISPR/Cas9 (CRISPR) technique has been used to modify genes in animals, plants and fungi, organisms different from and more complex than the bacteria in which the molecular components originally evolved. It has undergone several refinements since its introduction, each iteration proving more accurate, with fewer off-target effects. Show More Summary
A new, evidenced-based clinical practice guideline on molecular biomarker testing for patients with colorectal cancer identifies opportunities for improving patient outcomes.
Optimal protein synthesis requires bases in transfer RNAs to be modified. A key modification has been shown to involve an unusual two-step mechanism that entails the sequential activities of two enzymes. See Letter p.494
T cells of the immune system often fail to target cancer cells because they enter a dysfunctional state known as exhaustion. Molecular analysis of T-cell exhaustion provides insights into the clinical use of these cells.
Researchers from The University of Queensland's Institute for Molecular Bioscience (IMB) have developed a faster and more accurate method for assembling genomes which could help clinicians rapidly identify antibiotic-resistant infections.