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Are new therapies for Crohn's disease and chronic pancreatitis on the horizon?

Cellular and Molecular Gastroenterology and Hepatology (CMGH) is committed to publishing impactful digestive biology research covering a broad spectrum of themes in GI, hepatology and pancreatology. We wanted to share two new CMGH articles,...Show More Summary

Scientists predict cell changes that affect breast cancer growth

JUPITER, FL - April 28, 2016 - Designing effective new drugs, especially drugs to fight cancer, demands that you know as much as you can about the molecular workings of cancer growth. Without that, it's like planning to fight a war against an enemy you've never seen. read more

Stem cell study finds mechanism that controls skin and hair color

A pair of molecular signals controls skin and hair color in mice and humans -- and could be targeted by new drugs to treat skin pigment disorders like vitiligo, according to a report by scientists at NYU Langone Medical Center. read more

DNA Strings Turned Into Molecular Thermometers

At the University of Montreal scientists have created a DNA-based thermometer that is so tiny that it can be inserted into cells to read the temperature inside. The inspiration came from seeing naturally occurring molecules being used to sense the temperature in the biological world. Show More Summary

Scientists using artificial intelligence to develop tastier vegan foods (Video)

This food-tech startup is using artificial intelligence to create plant-based foods that taste and smell like their animal-based counterparts, down to the molecular level.

Coral 'toolkit' allows floating larvae to transform into reef skeletons

Key components of the molecular 'toolkit' that allow corals to build their skeletons (called biomineralization) has been desicribed in that new article that also outlines when -- in the transformation from floating larvae to coral skeleton -- these components are used.

We share molecular armor with coral reefs

A new study has found that one particular molecule found in reef ecosystems plays a similar immunological role in corals as it does in humans. From an evolutionary standpoint, this suggests the molecule's immune function dates back at least 550 million years.

Chemists use DNA to build the world's tiniest thermometer

Researchers have created a programmable DNA thermometer that is 20,000x smaller than a human hair. One of the main advantages of using DNA to engineer molecular thermometers is that DNA chemistry is relatively simple and programmable. So, the research team has created various DNA structures that can fold and unfold at specifically defined temperatures.

We share a molecular armor with coral reefs

Coral reefs face many threats. Ocean acidification, algal takeover caused by overfishing and exploding populations of harmful microbes all jeopardize the health of the world's most productive and diverse marine ecosystems. read more

BIDMC Scientist Barbara B. Kahn, MD, Awarded Banting Medal from American Diabetes Association

Beth Israel Deaconess Medical Center's Barbara B. Kahn, MD, an international leader in the field of diabetes, endocrinology and metabolism whose research has identified fundamental molecular mechanisms underlying obesity, insulin resistance...Show More Summary

DNA Day 2016: Get tested, learn more about what makes you unique

On April 25, 1953, Nature first published the research spearheaded by James Watson and Francis Crick on the molecular structure of DNA. 63 years later, DNA analysis and manipulation play major roles in nearly every aspect of our liv...

Ultrafast photoelectron imaging grasps competition in molecular autoionization

Using time-, energy- and angular-resolved photoelectron imaging, a team of researchers has been able to make snapshots of coupled Rydberg orbitals evolving in time during an ultrafast autoionization process.

How vibrio cholera is attracted by bile revealed

A group of researchers has revealed their finding that the molecular mechanism that Vibrio cholerae, the etiological agent of cholera, is attracted by bile. This group has also successfully detected the ligand binding to the bacteria chemoreceptor in vivo for the first time. These results may significantly advance research on mechanism and control of V. cholerae.

New Study Confirms Importance of Body Image During Chemotherapy

A new study produced by an interdisciplinary team led by Prof. Antonio Giordano, director of the Sbarro Institute for Cancer Research and Molecular Medicine at Temple University, tracks the development process and efficacy of the Italian...Show More Summary

Cell-Penetrating Peptide Delivers Drugs on a Molecular Level

A team at Kennesaw State University have developed a novel cell-penetrating peptide (CPP) technology capable of carrying other molecular "cargos" directly into living cells, coupling with them and then successfully uncoupling after delivering its payload. Cargos can be therapeutic molecules like antibodies that fight against parasites and diseases, or anti-cancer proteins.

Genes that control smooth muscle contraction identified

A new molecular pathway has been identified that is critical for maintaining the smooth muscle tone that allows the passage of materials through the digestive system.

How skeletal stem cells form the blueprint of the face

Timing is everything when it comes to the development of the vertebrate face. In a new study, researchers have identified the roles of key molecular signals that control this critical timing.

Gateway to the brain

Scientists have derived a structural model of a transporter at the blood-brain barrier called Mfsd2a. This is the first molecular model of this critical transporter, and could prove important for the development of therapeutic agents that need to be delivered to the brain --- across the blood-brain barrier. Show More Summary

Cpf1: CRISPR-enzyme scissors cutting both RNA and DNA

Scientists delineate molecular details of a new bacterial CRISPR-Cpf1 system and open possible avenue for alternative gene editing uses like targeting several genes in parallel.

UMMS scientists identify genes that control smooth muscle contraction

WORCESTER, MA - Researchers at UMass Medical School have identified a new molecular pathway critical for maintaining the smooth muscle tone that allows the passage of materials through the digestive system. This finding, based on studying...Show More Summary

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