Trend Results : Molecular

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CRISPR genetic editing takes another big step forward, targeting RNA

Scientists create new molecular scissors to correct protein imbalance in cellular model of dementia.

Potential cognitive effects of targeted drugs in children may be reversible with therapy

(American Association for Cancer Research) Young mice that received molecularly targeted therapies used to treat brain cancer in human patients sustained cognitive and behavioral deficits, but the deficits were largely reversible through environmental stimulation and physical exercise. Show More Summary

Cancer comes back all jacked up on stem cells

After a biopsy or surgery, doctors often get a molecular snapshot of a patient's tumor. This snapshot is important - knowing the genetics that cause a cancer can help match a patient with a genetically-targeted treatment. But recentShow More Summary

Molecular doorstop could be key to new tuberculosis drugs

(Rockefeller University) In discovering how an antibiotic kills the bacteria that cause tuberculosis, scientists open the door to new treatments for the disease -- and possibly others, as well.

Potential new way to limit antibiotic resistance spreading

(European Molecular Biology Laboratory) One of the biggest current threats to global health is the rise of multi-drug resistant bacteria, caused by the spreading of antibiotic resistance amongst them. In an attempt to help fight this threat, EMBL researchers have unraveled the molecular basis of a major antibiotic resistance transfer mechanism. Show More Summary

New imaging approach offers unprecedented views of staph infection

(Vanderbilt University Medical Center) Eric Skaar, Ph.D., M.P.H., and colleagues at Vanderbilt have combined multiple types of molecular imaging to probe an invasive Staphylococcus aureus infection in the mouse. Their integrated imaging...Show More Summary

Helle Ulrich receives ERC Proof of Concept Grant for her research on ubiquitin

(Johannes Gutenberg Universitaet Mainz) Molecular biologist Professor Helle Ulrich from the Institute of Molecular Biology and Johannes Gutenberg University Mainz has been awarded a Proof of Concept Grant from the European Research Council. Show More Summary

Improved capture of cancer cells could aid in disease tracking

(UNC Lineberger Comprehensive Cancer Center) In the journal Clinical Cancer Research, researchers reported that by forcing cancer cells to slow down and developing stronger molecular traps for them, they could identify large numbers of the cells in cancer patients undergoing radiation therapy.

PDUFA Dates, AdComms and Approvals – 2018 So Far

There would seem to be a momentum for new approvals brought on by a number of circumstances, not the least of which is the fact that last year saw a record number (47) of approvals for new molecular entities (NMEs), … Continue readi...

New method offers first look at super-cold carbon molecules

Science just got a little cooler in the Air Force Research Laboratory. Using a helium droplet method that chills molecular species to nearly absolute zero, researchers in the Aerospace Systems Directorate's Turbine Engine Division are able see carbon clusters, including soot precursors in combustion, in a completely new way.

NASA's Webb Telescope to make a splash in search for interstellar water

(NASA/Goddard Space Flight Center) Water is crucial for life, but how do you make water? Cooking up some H2O takes more than mixing hydrogen and oxygen. It requires the special conditions found deep within frigid molecular clouds, where dust shields against destructive ultraviolet light and aids chemical reactions. Show More Summary

Astronaut’s DNA different than his twin’s after year in space

NASA researchers found that astronaut Scott Kelly experienced molecular changes during his groundbreaking space flight, and while most of his genes returned to normal 7% have not yet changed back.

Assessing Recent Changes in the Pace of Secondary Aging

18 hours agoHealth / Aging : Fight Aging

Biological age, as opposed to chronological age, is driven by the intrinsic processes of primary aging, the accumulation of molecular damage outlined in the SENS rejuvenation research proposals, but also by the influence of the environment, secondary aging. Show More Summary

Study suggests molecular imaging strategy for determining molecular classifications of NSCLC

(Molecular Imaging Research Center (MIRC) of Harbin Medical University) Recent findings suggest a novel positron emission tomography (PET) imaging approach determining epidermal growth factor receptor (EGFR) mutation status for improved lung cancer patient management. The findings are published in the March 7 issue of Science Translational Medicine.

Novel PET imaging agent targets copper in tumors, detects prostate cancer recurrence early

(Society of Nuclear Medicine and Molecular Imaging) An Italian study featured in the March issue of The Journal of Nuclear Medicine demonstrates that a novel nuclear medicine imaging agent targeting copper accumulation in tumors can detect prostate cancer recurrence early in patients with biochemical relapse (rising prostate-specific antigen [PSA] level).

'Rheostat' identified that helps regulate cell death versus survival decisions

St. Jude Children's Research Hospital scientists have determined how a protein's disordered region serves as a molecular rheostat to help regulate cell survival.

Study suggests molecular imaging strategy for determining molecular classifications of NSCLC

Recent findings suggest a novel positron emission tomography (PET) imaging approach determining epidermal growth factor receptor (EGFR) mutation status for improved lung cancer patient management. The findings are published in the Mar. 7 issue of Science Translational Medicine.

New test extends window for accurate detection of Zika

(Columbia University's Mailman School of Public Health) Diagnosis of Zika infection is complex. Molecular tests for exposure are only reliable in the first two to three weeks after infection. Antibody tests are confounded by cross-reactivity of antibodies to Zika with similar viruses like dengue and yellow fever. Show More Summary

New molecular target could help ease asthma

Researchers have shown that the protein vascular endothelial growth factor A -- or VEGFA -- plays a major role in the inflammation and airway obstruction associated with asthma. The finding may eventually lead to new asthma treatments targeting VEGFA.

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