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Experts Uncover First Molecular Events of Organ Rejection

Researchers at the University of Pittsburgh and the University of Toronto have uncovered the first molecular steps that lead to immune system activation and eventual rejection of a transplanted organ.

Kopchicks give $10.5 million gift to MD Anderson UTHealth Graduate School for fellows

(University of Texas Health Science Center at Houston) Just as he has changed the lives of people suffering from a devastating genetic disease, molecular endocrinologist John J. Kopchick, Ph.D., and his wife, Charlene, of Athens, Ohio,...Show More Summary

Atomic imperfections move quantum communication network closer to reality

An international team led by the University of Chicago's Institute for Molecular Engineering has discovered how to manipulate a weird quantum interface between light and matter in silicon carbide along wavelengths used in telecommunications.

A single electron's tiny leap sets off 'molecular sunscreen' response

In experiments at the Department of Energy's SLAC National Accelerator Laboratory, scientists were able to see the first step of a process that protects a DNA building block called thymine from sun damage: When it's hit with ultraviolet light, a single electron jumps into a slightly higher orbit around the nucleus of a single oxygen atom.

Combined molecular biology test is the first to distinguish benign pancreatic lesions

(American College of Surgeons) When performed in tandem, two molecular biology laboratory tests distinguish, with near certainty, pancreatic lesions that mimic early signs of cancer but are completely benign. The lesions almost never progress to cancer, so patients may be spared unnecessary pancreatic cancer screenings or operations. Show More Summary

MD Anderson UTHealth Graduate School Receives $10.5 Million Gift

Just as he has changed the lives of people suffering from a devastating genetic disease, molecular endocrinologist John J. Kopchick, Ph.D., and his wife, Charlene, of Athens, Ohio, are paving the way for future scientists to do the same with a transformative $10.5 million gift to The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences.

UV-sensing protein in the brain of a marine annelid zooplankton

Researchers at Institute for Molecular Sciences reported that a photoreceptive protein expressed in the brain a marine annelid zooplankton (Platynereis dumerilii) is UV-sensitive. This work was carried out as a collaborative work of Drs. Show More Summary

Scientists uncover potential mechanism for HPV-induced skin cancer

(PLOS) Scientists have identified a molecular pathway by which some types of human papilloma virus (HPV) might increase the risk of skin cancer, particularly in people with the rare genetic disorder epidermodysplasia verruciformis (EV). The novel pathway is described in PLOS Pathogens.

Molecular biology: A liquid reservoir for silent chromatin

3 days agoAcademics : Nature AOP

The protein HP1 mediates compaction of DNA into a repressive structure called heterochromatin. Analysis reveals that HP1 has liquid-like properties, offering a fresh perspective on genome organization.

Selective sp3 C–H alkylation via polarity-match-based cross-coupling

3 days agoAcademics : Nature AOP

The functionalization of carbon–hydrogen (C–H) bonds is one of the most attractive strategies for molecular construction in organic chemistry. The hydrogen atom is considered to be an ideal coupling handle, owing to its relative abundance in organic molecules and its availability for functionalization at almost any stage in a synthetic sequence. Show More Summary

Molecular test for common causes of vaginitis receives FDA approval

(Johns Hopkins Medicine) Johns Hopkins researchers report that a molecular diagnostic test accurately distinguishes among the three most common causes of vaginitis, an inflammation of vaginal tissue they say accounts for millions of visits to medical clinics and offices in the US each year.

Enzyme catalyzed decomposition of 4-hydroxycyclophosphamide

(Bentham Science Publishers) Oxazaphosphorine cytostatics (Cyclophosphamide, Ifosfamide) are often used and very effective anticancer agents; but so far little is known about the molecular basis for the antitumor effect.

Optical centrifuge magnetizes molecular gas

Technique could produce large numbers of spin-polarized electrons

The Journal of Nuclear Medicine impact factor increases

(Society of Nuclear Medicine) The Journal of Nuclear Medicine (JNM) -- the flagship publication of the Society of Nuclear Medicine and Molecular Imaging -- is again ranked among the top medical imaging journals worldwide, according to the 2016 Journal Citation Reports© published by Thomson Reuters. Show More Summary

Thousands of genes influence most diseases, Stanford researchers report

(Stanford University Medical Center) In a provocative new perspective piece, Stanford researchers say that disease genes are spread uniformly across the genome, not clustered in specific molecular pathways, as has been thought.

A top Wall Street analyst explains why you should put just as much work into a LinkedIn message as an interview

Matthew Eckler has an unusual background for a Wall Streeter. He didn't attend a top business school, nor did he get a degree in finance of economics. The senior biotech analyst holds a BS in biology and a PhD in molecular biology. And...Show More Summary

Unlock molecular secrets with mobile game BioBlox2-D

(Imperial College London) BioBlox2D is a new free mobile computer game inspired by tackling one of the hardest problems in biological science -- how molecules fit together.

The anatomy of Orion

The Orion molecular cloud is a large complex of hot young stars, nebulae, and dark clouds of gas and dust located in the constellation of Orion. Two particularly famous sights in the night sky, the Orion Nebula and the Horsehead Nebula, are members of this complex, which is relatively nearby, only about 1500 light-years away. Show More Summary

Blood-based lung cancer test shows promise: Mayo Clinic Radio Health Minute

In a new study by Mayo Clinic and the molecular diagnostics company Exact Sciences, a blood-based cancer test has shown high accuracy for detecting lung cancer at all stages. "We were very pleased to see those results," says Dr. David Ahlquist, a Mayo Clinic gastroenterologist who previously worked with Exact Sciences to develop a colon cancer […]

Using photoluminescent nanorods as ultimate probes of fluid flow

A Franco-Dutch international collaboration involving researchers from the laboratories of Condensed Matter Physics and Hydrodynamics at Paris-Saclay University and the Van't Hoff Institute for Molecular Sciences at the University of Amsterdam has resulted in a new method for very precise determination of fluid flow in capillary networks in realtime. Show More Summary

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