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The influence of the Isthmus of Panama in the evolution of freshwater shrimps in America

The evolution of freshwater shrimps species living in both sides of Central America, isolated by the closure of Isthmus of Panama (3 million years ago) were studied by molecular tools. Despite the small likelihood of species crossing...Show More Summary

Sialic acid shields human cells from attack by immune system

Biochemists have identified molecular structures that allow the immune system to tell friend from foe. The researchers identified and crystallized a complex that forms the contact point between the healthy human cell and the complement system. Show More Summary

Black Yeasts, Black Lichens and Rotting Wood: the Chaetothyriomycetidae

Pyrenula cruenta, copyright Gary Perlmutter. There is no denying that the advent of molecular phylogenetic analysis has been a boon for fungal systematics. It has allowed a much greater resolution of relationships than was previously...Show More Summary

Excessive contact between cellular organelles disrupts metabolism in obesity

Researchers have found a novel mechanism causing type 2 diabetes that could be targeted to prevent or treat the disease. The research highlights a previously unrecognized molecular pathway that contributes to the malfunction of liver cells in obesity, leading to insulin resistance and diabetes.

Alzheimer's - Molecular signals cause brain cells to switch into a hectic state

The research team showed that the pathological changes of the astrocytes can be mitigated by pharmacological treatment in Alzheimer's disease. By+Alzheimer's Reading Room The triggering molecules turned out to be energy carriers of the...Show More Summary

Novel regulatory mechanism for cell division found

A protein kinase or enzyme known as PKM2 has proven to control cell division, potentially providing a molecular basis for tumor diagnosis and treatment. A study, led by Zhimin Lu, M.D., Ph.D., professor of neuro-oncology at The University...Show More Summary

Novel Regulatory Mechanism for Cell Division Found

A protein kinase or enzyme known as PKM2 has proven to control cell division, potentially providing a molecular basis for tumor diagnosis and treatment.

Results of new drug, ASP8273, show response in patients with treatment-resistant NSCLC

Barcelona, Spain: In a second presentation looking at new ways of treating non-small cell lung cancer (NSCLC) that has both the EGFR and T790M mutations, researchers will tell the 26th EORTC-NCI-AACR [1] Symposium on Molecular Targets...Show More Summary

Researchers report way to target hard-to-hit site in disease pathway

CINCINNATI - Researchers have successfully targeted an important molecular pathway that fuels a variety of cancers and related developmental syndromes called "Rasopathies." Reporting their results Nov. 20 in Chemistry & Biology, scientists...Show More Summary

SCiO, A Portable Consumer Molecular Scanner That Can be Used With Food, Plants and Medications

5 days agoOdd : Laughing Squid

SCiO is a palm-sized spectrometer for consumers that scans a range of objects including food, plants, plastics and wood to gain information through their molecular footprint. Using the smartphone-enabled device, consumers get quick access...Show More Summary

Putting snails in the microwave…for science!

Yahoo answers tells me I shouldn’t put snails in the microwave, but this paper tells me otherwise: Galindo LA, Puillandre N, Strong EE, Bouchet P (2014) Using microwaves to prepare gastropods for DNA barcoding. Molecular Ecology Resources, 14(4): 700-705. This paper is so simple, yet so epic in so many ways: We have experimented with […]

Biochemists build largest synthetic molecular 'cage' ever

Biochemists have created the largest protein ever that self-assembles into a molecular cage. Their designed protein, which does not exist in nature, is hundreds of times smaller than a human cell. The research could lead to 'synthetic vaccines' that protect people from the flu, HIV and perhaps other diseases. Show More Summary

UCLA biochemists build largest synthetic molecular 'cage' ever

UCLA biochemists have created the largest-ever protein that self-assembles into a molecular "cage." The research could lead to synthetic vaccines that protect people from the flu, HIV and other diseases. At a size hundreds of times smaller...Show More Summary

When did insects evolve?

Just consult the chart. Be sure to click on the image to see it at a better resolution! This is from a paper that looked at the molecular phylogenies, and worked out estimated branch times. I like it. I want it on my wall. Insects are the most speciose group of animals, but the phylogenetic…

Phage-Derived Catalysts

I've been enjoying this recent paper in JACS, but then I always like to see intersections of molecular biology with organic synthesis. The authors, from CUNY and the University of Strathclyde, are using a phage display library to see if they can come up with displayed peptide combinations that are catalytic. Show More Summary

Cue Draws In $7.5M For Its Health Tracking Lab-In-A-Box

San Diego-based startup Cue believes the future of personal health fits in a small plastic box that — linked up to a smartphone or tablet — will give consumers the ability to monitor and quantify their personal health at a molecular level, right from the comfort of their own home. Read More

Synergistic effects of acute warming and low pH on cellular stress responses of the gilthead seabream Sparus aurata

The present study assesses the resilience of the Mediterranean gilthead seabream (Sparus aurata) to acute warming and water acidification, using cellular indicators of systemic to molecular responses to various temperatures and CO2 concentrations. Show More Summary

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