Hsp70 chaperone molecules help other proteins to fold, and were thought to bind mainly to unfolded proteins. Single-molecule experiments now suggest that Hsp70s can also stabilize almost fully folded proteins.
Binary and multiple star systems result from the fragmentation of dense material in young molecular clouds. Observations reveal that this can occur on small scales, supporting a previous model of star formation. See Letter p.483
Drug discovery is a long and difficult process that requires a comprehensive understanding of the molecular structures of compounds under investigation. It’s difficult to have an idea of the precise shape of complex molecules such as...Show More Summary
(University of the Basque Country ) Nearly 70 percent of the drugs currently being developed target membrane receptors. That is why in order to be able to advance in the development of more specific and more efficient drugs, the molecular mechanism that regulates the activity of these receptors needs to be deciphered. Show More Summary
Nearly 70% of the drugs currently being developed target membrane receptors. Located outside the cell, these receptors play a decisive role in transmitting information to the inside of the cell. That is why in order to be able to advance...Show More Summary
(Indiana University) Medical researchers at Indiana University have found evidence for a link between prostate cancer, which affects millions of men age 50 and older, and Ewing's sarcoma, a rare form of cancer that affects children and young adults. The results appear in the journal Cell Reports.
(Texas Biomedical Research Institute) A scientist was recently awarded a grant from the National Institutes of Health to study and identify molecular mechanisms underlying early atherosclerosis.
(Max Delbrück Center for Molecular Medicine in the Helmholtz Association) In order to use the CRISPR-Cas9 system to cut genes, researchers must design an RNA sequence that matches the DNA of the target gene. The new 'CrispRGold' program helps scientists to identify the most effective and specific RNA sequences. Show More Summary
(Charité - Universitätsmedizin Berlin) Scientists at the Charité - Universitätsmedizin Berlin found which molecules of the house dust mites are initially targeted by the immune system of children developing, even years later, allergic rhinitis and asthma. Show More Summary
(University of California - San Diego) Viruses hijack the molecular machinery in human cells to survive and replicate, often damaging those host cells in the process. Researchers at the University of California San Diego School of Medicine discovered that, for cytomegalovirus (CMV), this process relies on a human protein called CPEB1. Show More Summary
Viruses hijack the molecular machinery in human cells to survive and replicate, often damaging those host cells in the process. Researchers at the University of California San Diego School of Medicine discovered that, for cytomegalovirus (CMV), this process relies on a human protein called CPEB1. Show More Summary
Scientists at the Centro Nacional de Enfermedades Cardiovasculares Carlos III (CNIC) have defined the molecular organization underlying energy production in living cells. The discovery, published in the journal Nature, sheds light on...Show More Summary
(Baylor College of Medicine) Analysis of vast amounts of molecular data from a set of more than 1,000 non-small cell lung cancers identifies distinct subtypes, each with its own molecular profile and potentially different response to therapy.
In a discovery that advances the understanding of how marijuana works in the human body, an international group of scientists has, for the first time, created a three-dimensional atomic-level image of the molecular structure activated by tetrahydrocannabinol (THC), the active chemical in marijuana.
(National University of Singapore) Researchers from the Mechanobiology Institute at the National University of Singapore have revealed the molecular events leading to the regulation of cell growth and proliferation in response to stiffness of the extracellular matrix that surrounds them.
More than 100 million years ago, this molecular switch may have helped turn lizards into serpents.
Biologists have been contemplating evolutionary change since Charles Darwin first explained it.
Imagine what it would be like to watch how the individual atoms of molecules rearrange during a chemical reaction to form a new substance, or to see the compounds of DNA move, rearrange and replicate. Such capability would give unprecedented insight to understand and potentially control the processes.
(ICFO-The Institute of Photonic Sciences) Scientists can now directly track the locations of all the atoms of an entire molecule while one of its bonds breaks and a single proton escapes.
Album releases are generally a pretty serious undertaking, but I imagine the process is remarkably less stressful if the artist doing the releasing is constantly creating out of sheer impulse or enjoyment. It’s a lot easier to honor a request for a rainbow painting if all you do during your downtime is paint rainbows. Show More Summary