This isn't the first paper I've seen to argue the point that there should be a greater focus on tau aggregation in Alzheimer's disease, and that tau may be more important to the progression of the condition. As I'm sure the readers here are aware, Alzheimer's is characterized by the buildup of both amyloid-? and tau in the brain. Show More Summary
Great news: Scientists are making progress in preventing Alzheimer’s among mice. Humans, however, are another story. A recent study by the UK’s National Institution of Aging (NIA) suggests a potential new target for […] The post Alzheimer’s Treatment Works in Mice, But What About Humans? appeared first on Geek.com.
Researchers here make an effort to link the age-related accumulation of senescent cells in vascular tissue with some of the better known biochemistry of Alzheimer's disease. Progressive vascular dysfunction is an important componentShow More Summary
(McGill University) Frequently encountered in the elderly, Alzheimer's is considered a neurodegenerative disease, which means that it is accompanied by a significant, progressive loss of neurons and their nerve endings, or synapses. A joint French and Canadian study published in Scientific Reports now challenges this view.
Absent any greater context on Alzheimer's disease research, one might look back at the past twenty years of clinical trials and consider this medical condition to be an insurmountable obstacle at our present stage of progress in biotechnology. Show More Summary
Few afflictions carry the existential dread that dementia does. While it's bad enough that there isn't a treatment that can stop the progression of Alzheimer's once it's apparent, a new series of papers published this week suggests something even more disheartening. There might be nothing you can do to prevent it, either. More »
The research noted here improves the understanding of how inflammation acts to drive the progression of Alzheimer's disease, despite being secondary to the well-known deposition of amyloid-? observed in the condition. Alzheimer's disease is considered to be in part an inflammatory condition. Show More Summary
According to a study by scientists of the German Center for Neurodegenerative Diseases (DZNE) and the University of Bonn now published in the journal "Nature", inflammatory mechanisms caused by the brain's immune system drive the progression of Alzheimer's disease. Show More Summary
Inflammatory mechanisms caused by the brain's immune system drive the progression of Alzheimer's disease, according to new research. These findings, which rely on a series of laboratory experiments, provide new insights into pathogenetic mechanisms that are believed to hold potential for tackling Alzheimer's before symptoms manifest. Show More Summary
Researchers will be using powerful lasers to look into the brains of animals to watch neurons firing as a way study the progression of neurodegenerative diseases.
(University of Colorado at Boulder) Boulder researchers are embarking on a new project to study the progression of neurodegenerative diseases like Alzheimer's by using a new laser technique to measure neurons firing deep inside animal brains.
Using ‘Raman’ optical technology, scientists can now produce images of brain tissue that is affected by Alzheimer’s disease. The images include the surrounding areas, already showing changes.
Astrocytes are one of a number of different classes of supporting cells of the brain, and researchers here investigate how they might be involved in the progression of Alzheimer's disease - though with the caution they they are looking at early-onset Alzheimer's linked to specific mutations. Show More Summary
Alzheimer’s disease is one of those conditions where genetics is known to play a profound role but is not the sole factor in disease development and progression. The evidence is mounting that the environment has a great deal to do with the development of this neurodegenerative disorder. Moreover, it is now known that the right […]
The lack of concrete progress in the amyloid clearance approach to Alzheimer's disease, despite significant investment and many clinical trials over the past decade, has led to a great deal of theorizing in the research community. Is...Show More Summary
If you Google the search terms “physical activity” and “Alzheimer’s disease,” you will be served up a long list of links that almost exclusively tout the notion that exercise could help prevent or slow down the progression of dementia. They are reassuring and hopeful messages but arguably not representative of the mixed science on this […]
(McGill University) Simple odor identification tests may help track the progression of Alzheimer's disease before symptoms actually appear, particularly among those at risk.
Researchers have discovered that defects in the transport of lysosomes within neurons promote the buildup of protein aggregates in the brains of mice with Alzheimer's disease. The study suggests that developing ways to restore lysosome transport could represent a new therapeutic approach to treating the neurodegenerative disorder.
(Rockefeller University Press) Researchers from Yale University School of Medicine have discovered that defects in the transport of lysosomes within neurons promote the buildup of protein aggregates in the brains of mice with Alzheimer's disease. Show More Summary
Paul Alper points to this news report by Ian Sample, which goes: Psychologists believe they can identify progressive changes in work of artists who went on to develop Alzheimer’s disease The first subtle hints of cognitive decline may reveal themselves in an artist’s brush strokes many years before dementia is diagnosed, researchers believe... Show More Summary