Alzheimer's disease (AD) progresses inside the brain in a rising storm of cellular chaos as deposits of the toxic protein, amyloid-beta (A?), overwhelm neurons. An apparent side effect of accumulating A? in neurons is the fragmentation...Show More Summary
Though shot in the stolidly inconspicuous style of a low-rated cable drama, Still Alice is rarely anything short of compelling, in part because its sense of progression and scale offers such a distinctively unsentimental take on the terminal-countdown tearjerker. Show More Summary
Aricept is not a cure for Alzheimer's disease, and it does not stop Alzheimer's. When it works well, it is designed to slow the progression of Alzheimer's and improve behavior. Bob DeMarcoAlzheimer's Reading Room The use of Aricept for Alzheimer's disease is controversial. Show More Summary
"Inadequate funding remains the single most important impediment to progress in achieving the research goal of the Alzheimer's National Plan." By Bob DeMarco Alzheimer's Reading Room The U.S. Government has initiated a major effort to prevent and effectively treat Alzheimer's disease by 2025. Show More Summary
Most of the research community proceeds under the assumption that amyloid, deposits of misfolded proteins that form in tissues, is a causative agent in Alzheimer's disease. Amyloid levels rise with age, probably due to progressive failure of clearance mechanisms. Show More Summary
A new preclinical study indicates that THC, the active ingredient in marijuana, may slow or halt the progression of Alzheimer's disease. Alzheimer's Reading Room THC (Tetrahydrocannabinol) is the active ingrient in marijuana that produces a psychoactive reaction. Show More Summary
Tampa, FL (Aug. 26, 2014) -- Extremely low levels of the compound in marijuana known as delta-9-tetrahydrocannabinol, or THC, may slow or halt the progression of Alzheimer's disease, a recent study from neuroscientists at the University...Show More Summary
Research will look to produce compound derivatives of punicalagin for a drug that would treat neuro-inflammation and slow down the progression of Alzheimer's disease, scientists report. The onset of Alzheimer's disease can be slowed and some of its symptoms curbed by a natural compound that is found in pomegranate. Show More Summary
Even though Lewy body dementia is second only to Alzheimer's disease as the most common cause of progressive dementia, affecting 1.3 million Americans, the symptoms of LBD are not well recognized by many physicians, especially primary care physicians and other general practitioners. Show More Summary
While there has been progress made in the fight against Alzheimer's, our understanding of the dispiriting disease remains somewhat limited, with a definitive cure yet to be found. The latest development comes at the hands of researchers...Show More Summary
American artist William Utermohlen (1933-2007) was diagnosed with Alzheimer’s disease in 1995. For the remaining five years of his life, he painted self-portraits which revealed the progression of the disease and its effects, as well as Mr. Utermohlen's heartbreaking, desperate attempts to understand what was happening to him.
Currently, no cure exists for Alzheimer's disease, the devastating neurological disease affecting more than 5 million Americans. But scientists are now reporting new progress on a set of compounds, initially developed for cancer treatment, that shows promise as a potential oral therapy for Alzheimer's. Their study appears in ACS' Journal of Medicinal Chemistry. read more
A type of immune cell widely believed to exacerbate chronic adult brain diseases, such as Alzheimer's disease and multiple sclerosis, can actually protect the brain from traumatic brain injury and may slow the progression of neurodegenerative diseases, according to research. Show More Summary
Roche’s Genentech unit just released a mid-stage study of a drug that seeks to slow the progression of Alzheimer’s by blocking the accumulation of a protein called amyloid beta. Like every other medicine that has attempted this approach – which remains the main one being pursued by drug companies to battle Alzheimer’s – the drug [...]
Frontotemporal dementia (FTD) is a cluster of progressive diseases that affect the regions of the brain that control personality, behavior, language, and decision-making. By Carole B. LarkinAlzheimer's Reading RoomAre you sure its Alzheimer's?...Show More Summary
While the drug, crenezumab, did not slow progression of the disease over all, at the highest doses it seemed to delay a decline in mental ability in patients with mild Alzheimer’s.
Researchers have conducted the first-ever analysis of clinical trials for Alzheimer's disease, revealing an urgent need to increase the number of agents entering the AD drug development pipeline and progressing successfully towards new therapy treatments.
Patients with Alzheimer's disease run a high risk of seizures. While the amyloid-beta protein involved in the development and progression of Alzheimer's seems the most likely cause for this neuronal hyperactivity, how and why this elevated activity takes place hasn't yet been explained – until now. read more
As my mother continued her decline from Alzheimer’s, it was disconcerting to ride the roller coaster of emotions. Wearing the daughter/caregiver hat I felt powerless to change the progression of her disease. By Elaine C PereiraAlzheimer's Reading Room As an Occupational herapist I believe it is. Show More Summary
His memory loss became apparent first. Like many people experiencing Alzheimer's in its early stages, my father began misplacing important objects and forgetting the names of people. As the disease progressed, his conversational skills...Show More Summary