A protein involved in the progression of Alzheimer's disease also has properties that could be helpful for human health, a research study has found. The discovery helps researchers better understand the complicated brain chemistry behind the development of Alzheimer's disease.
Pharmaceutical researchers on Wednesday presented new data from the clinical trials of three drugs that, the scientists said, show promise for slowing the progression of Alzheimer’s disease.Researchers presented new analyses of research data on drugs produced by Eli Lilly, Roche and Biogen. Show More Summary
I experienced the worst and best customer service experiences of my life from competing companies on the same day a few years ago. My widowed father's Alzheimer's disease had progressed to the point where he could no longer remain in an independent living apartment in his over-60 community. Show More Summary
Above, Dr. Matthew Norton, head of policy at Alzheimer’s Research UK, discusses the new drug. Scientists appear to have made a breakthrough in the battle against Alzheimer’s disease after announcing test results for a drug that appears...Show More Summary
A study sheds light on the influences of genetics on why some type 2 diabetics are at high risk for developing Alzheimer’s disease. While previous studies strongly suggested a causative role of diabetes in the onset and progression of Alzheimer’s disease dementia, the specific mechanistic interactions connecting diabetes and Alzheimer’s disease had not been previously described.
More than 4,000 scientists from around the world will gather in Washington this week to share the latest findings and ideas on Alzheimer’s disease, with some saying that the odds of finding effective treatments look promising even as an aging society increases the urgency of finding a cure.Read full article >>
Dementia is characterized by a progressive and debilitating decline in cognition, function and behavior. Its numbers are staggering: according to the World Health Organization, the total number of people with dementia worldwide in 2010 was estimated at 35.6 million and predicted to nearly double every 20 years, to 65.7 million in 2030 and 115.4 million […]
The amyloid cascade hypothesis of Alzheimer's disease (AD) posits that sticky aggregations or plaques of amyloid-beta peptides accumulate over time in the brain, triggering a series of events that ultimately result in the full-blown neurodegenerative disorder. Show More Summary
UC San Diego School of Medicine researchers report that the amyloid cascade hypothesis, long believed to describe the pathology of Alzheimer's disease, is not a fixed and invariable sequence of events. Rather, early indicators or biomarkers of the neurodegenerative condition vary by individual, making preclinical diagnoses more challenging.
Arguably the most urgent and seemingly intractable of all the healthcare issues facing us today is Alzheimer’s disease (AD), which is marked by progressive, inexorable loss of intellectual and social skills and ultimately, death. AsShow More Summary
A brain protein believed to be a key component in the progress of dementia can cause memory loss in healthy brains even before physical signs of degeneration appear, according to new research.
Making a connection is essential for the well being of people living with Alzheimer’s. There are four special activities that can typically reach and engage people at any point in the disease’s progression, even with those in the later stages who may no longer talk or smile, let alone recognize love ones. Show More Summary
More than 5 million Americans are living with Alzheimer's with no cure or treatment to reverse the progression. So medical professionals are constantly seeking ways to improve quality of life for their patients. One new method is a pilot...Show More Summary
The slow progress towards viable therapies for Alzheimer's disease based on clearance of ?-amyloid, such as via immunotherapy, has led to a broadening of approaches. Many research groups are looking at other theories on causative mechanisms...Show More Summary
From MedPage Today: CSF Biomarker May Predict Early AD Progression. Cerebrospinal fluid (CSF) levels of a certain brain protein may be a helpful predictor of progression to Alzheimer’s disease. Diabetes More Likely in Children in Stressful Homes. Show More Summary
A drug discovery could hold promise in the fight against the devastating effects of Alzheimer's Disease. Scientists, using a animal model, have completed research to suggest that the drug Edaravone could alleviate the progressive cognitive deficits of Alzheimer's Disease, a major social and economic burden worldwide.
Alzheimer's Reading Room By examining more than 3,600 postmortem brains, researchers at the Mayo Clinic found that the progression of dysfunctional tau protein drives the cognitive decline and memory loss seen in Alzheimer’s disease....Show More Summary
By examining more than 3,600 postmortem brains, researchers have found that the progression of dysfunctional tau protein drives the cognitive decline and memory loss seen in Alzheimer’s disease.
The struggle to show meaningful progress in treatment of Alzheimer's disease via clearance of amyloid has fueled significant investment into alternative hypotheses regarding the disease process. The biochemistry of Alzheimer's - andShow More Summary
By examining more than 3,600 postmortem brains, researchers at Mayo Clinic's campuses in Jacksonville, Florida, and Rochester, Minnesota, have found that the progression of dysfunctional tau protein drives the cognitive decline and memory loss seen in Alzheimer's disease.