Multivariate analysis of cognitive tests in Alzheimer's disease identifies five distinct groups of Alzheimer's disease patients, and suggests that multivitamins might slow progression only in certain groups.
Inflammation in the brain contributes to the progression of Alzheimer's disease. This has been known for some time, but there has been surprisingly little progress in building anti-inflammatory treatments. Some years ago, one approach using existing anti-inflammatory drugs failed in clinical trials, for example. Show More Summary
The way in which Alzheimer's brain changes progress is linked to poor control of protein in specific areas of the brain. New research maps these changes.
Researchers have identified a protein essential for building memories that appears to predict the progression of memory loss and brain atrophy in Alzheimer's patients. Their findings suggest there is a link between brain activity and the presence of this protein.
AMES, Iowa - Iowa State University researchers have identified a protein essential for building memories that appears to predict the progression of memory loss and brain atrophy in Alzheimer's patients. read more
A drug that targets tau tangles in the brain has produced strong results in a large clinical trial, slowing the progression of the disease in hundreds of people
Long-term treatment with broad spectrum antibiotics decreased levels of amyloid plaques, a hallmark of Alzheimer's disease, and activated inflammatory microglial cells in the brains of mice in a new study by neuroscientists from the University of Chicago.
Scientists at the Montreal Neurological Institute and Hospital have used a powerful tool to better understand the progression of late-onset Alzheimer's disease (LOAD), identifying its first physiological signs. read more
Scientists have used a powerful tool to better understand the progression of late-onset Alzheimer's disease (LOAD), identifying its first physiological signs. Rsearchers analyzed more than 7,700 brain images from 1,171 people in various...Show More Summary
Scientists may have overcome a major roadblock in the development of Alzheimer's therapies by creating a new technology to observe ? in the back of the eye ? progression of the disease before the onset of symptoms. Clinical trials are to start in July to test the technology in humans according to a paper recently published in Investigative Ophthalmology & Visual Science ( IOVS).
Three children of Broncos owner Pat Bowlen are no longer working for the team, the Denver Post reported Tuesday. Bowlen resigned control of the team in 2014 due to the progression of Alzheimer’s disease. Team president Joe Ellis assumed control and added the CEO title, while John Elway retained control of football operations, as general…
Bucking a century of progress, the US death rate rose in 2015 for the first time in a decade—largely due to increasing rates of overdose as well as suicide and Alzheimer’s, The New York Times reports. This article was originally published by The Influence, a news site that covers the full...
This paper explores the mechanisms by which the amyloid associated with the progression of Alzheimer's disease can be cleared naturally outside the brain. It raises the possibility that finding ways to reduce amyloid outside the brain will allow existing transport and clearance mechanisms to export and remove more of the amyloid from the brain. Show More Summary
After Alzheimer's, Parkinson's disease (PD) is the leading neurodegenerative disorder, affecting close to a million Americans, with 50,000 new cases diagnosed every year. A progressive disorder of the nervous system affecting movement, PD typically strikes adults in mid-life. Show More Summary
This research indicates that Tau is a better marker of progression to Alzheimer’s disease than amyloid beta. A study using a new PET imaging agent shows that measures of tau protein in the brain more closely track cognitive decline due to Alzheimer's disease compared with long-studied measures of amyloid beta. Show More Summary
Cedars-Sinai neuroscience researchers are studying whether extensive changes in lifestyle among patients with mild cognitive impairment can slow the progression of Alzheimer's disease. The research comes amid a sharp rise in the numbers of people affected by Alzheimer's disease, the most common form of dementia. Show More Summary
Thanks to positron emission tomography (PET) imaging of tau, which has only recently become available, researchers now report that tau tangles provide a good indication of cognitive decline in later stages of the disease. The study,Show More Summary
It’s well-established that the accumulation of two types of naturally occurring proteins in the brain—amyloid beta and tau—are central factors that contribute to the progression of Alzheimer’s disease. Up until this point, scientists have mainly focused their research on amyloid beta proteins, because there is no effective way to image tau. Show More Summary
Researchers have provided initial and somewhat speculative data to suggest that the decrease in body temperature that occurs in old age may speed the progression of mechanisms implicated in Alzheimer's disease: "We know that the incidence of Alzheimer's is low before age 65, but doubles every 5 to 6 years afterward. Show More Summary
Mayo Clinic's Dr. Ron Petersen is one of several experts testifying on Capitol Hill today at 2:30 pm EDT. The U.S. Senate Special Committee on Aging is holding a hearing on Alzheimer’s disease:“Finding a Cure: Assessing Progress Toward the Goal of Ending Alzheimer’s by 2025”. WATCH LIVE at 2:30 p.m. EDT. Chairman Collins, Ranking Member McCaskill will examine […]