Trend Results : Progression of Alzheimer's


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Arguing for Tau to be More Important than Amyloid-? in Alzheimer's Disease

3 days agoHealth / Aging : Fight Aging

This isn't the first paper I've seen to argue the point that there should be a greater focus on tau aggregation in Alzheimer's disease, and that tau may be more important to the progression of the condition. As I'm sure the readers here are aware, Alzheimer's is characterized by the buildup of both amyloid-? and tau in the brain. Show More Summary

Alzheimer’s Treatment Works in Mice, But What About Humans?

2 weeks agoTechnology / Gadgets : Geek.com

Great news: Scientists are making progress in preventing Alzheimer’s among mice. Humans, however, are another story. A recent study by the UK’s National Institution of Aging (NIA) suggests a potential new target for […] The post Alzheimer’s Treatment Works in Mice, But What About Humans? appeared first on Geek.com.

Senescent Cells Contribute to Vascular Dysfunction and the Biochemistry of Alzheimer's Disease

3 weeks agoHealth / Aging : Fight Aging

Researchers here make an effort to link the age-related accumulation of senescent cells in vascular tissue with some of the better known biochemistry of Alzheimer's disease. Progressive vascular dysfunction is an important componentShow More Summary

Alzheimer's disease: Neuronal loss very limited

(McGill University) Frequently encountered in the elderly, Alzheimer's is considered a neurodegenerative disease, which means that it is accompanied by a significant, progressive loss of neurons and their nerve endings, or synapses. A joint French and Canadian study published in Scientific Reports now challenges this view.

Two Examples of Recent Work on Novel Drug Candidates to Treat Alzheimer's Disease

last monthHealth / Aging : Fight Aging

Absent any greater context on Alzheimer's disease research, one might look back at the past twenty years of clinical trials and consider this medical condition to be an insurmountable obstacle at our present stage of progress in biotechnology. Show More Summary

Nothing We Know Of Stops Dementia: Broad Review Rules Out Drugs, Exercise, And Brain-Training Games

Few afflictions carry the existential dread that dementia does. While it's bad enough that there isn't a treatment that can stop the progression of Alzheimer's once it's apparent, a new series of papers published this week suggests something even more disheartening. There might be nothing you can do to prevent it, either. More »      

Describing an Inflammatory Feedback Loop in Alzheimer's Disease

2 months agoHealth / Aging : Fight Aging

The research noted here improves the understanding of how inflammation acts to drive the progression of Alzheimer's disease, despite being secondary to the well-known deposition of amyloid-? observed in the condition. Alzheimer's disease is considered to be in part an inflammatory condition. Show More Summary

Inflammation drives progression of Alzheimer's

According to a study by scientists of the German Center for Neurodegenerative Diseases (DZNE) and the University of Bonn now published in the journal "Nature", inflammatory mechanisms caused by the brain's immune system drive the progression of Alzheimer's disease. Show More Summary

Inflammation drives progression of Alzheimer's

Inflammatory mechanisms caused by the brain's immune system drive the progression of Alzheimer's disease, according to new research. These findings, which rely on a series of laboratory experiments, provide new insights into pathogenetic mechanisms that are believed to hold potential for tackling Alzheimer's before symptoms manifest. Show More Summary

Lasers Could Lead to Better Understanding of Neurodegenerative Conditions Like Alzheimer's

Researchers will be using powerful lasers to look into the brains of animals to watch neurons firing as a way study the progression of neurodegenerative diseases.

Lasers could lead to better understanding of neurodegenerative conditions like Alzheimer's

(University of Colorado at Boulder) Boulder researchers are embarking on a new project to study the progression of neurodegenerative diseases like Alzheimer's by using a new laser technique to measure neurons firing deep inside animal brains.

Imaging technique shows progress Alzheimer's disease

Using ‘Raman’ optical technology, scientists can now produce images of brain tissue that is affected by Alzheimer’s disease. The images include the surrounding areas, already showing changes.

Recent Research Implicates Astrocytes in the Progression of Alzheimer's Disease

3 months agoHealth / Aging : Fight Aging

Astrocytes are one of a number of different classes of supporting cells of the brain, and researchers here investigate how they might be involved in the progression of Alzheimer's disease - though with the caution they they are looking at early-onset Alzheimer's linked to specific mutations. Show More Summary

Environmental Factors in Development of Alzheimer’s Disease

Alzheimer’s disease is one of those conditions where genetics is known to play a profound role but is not the sole factor in disease development and progression. The evidence is mounting that the environment has a great deal to do with the development of this neurodegenerative disorder. Moreover, it is now known that the right […]

Microbial Theories of Alzheimer's Disease are Gaining Support

6 months agoHealth / Aging : Fight Aging

The lack of concrete progress in the amyloid clearance approach to Alzheimer's disease, despite significant investment and many clinical trials over the past decade, has led to a great deal of theorizing in the research community. Is...Show More Summary

Physical activity and dementia: another negative study, another void in news coverage

If you Google the search terms “physical activity” and “Alzheimer’s disease,” you will be served up a long list of links that almost exclusively tout the notion that exercise could help prevent or slow down the progression of dementia. They are reassuring and hopeful messages but arguably not representative of the mixed science on this […]

Could olfactory loss point to Alzheimer's disease?

(McGill University) Simple odor identification tests may help track the progression of Alzheimer's disease before symptoms actually appear, particularly among those at risk.

Role for lysosome transport in Alzheimer's disease progression revealed

Researchers have discovered that defects in the transport of lysosomes within neurons promote the buildup of protein aggregates in the brains of mice with Alzheimer's disease. The study suggests that developing ways to restore lysosome transport could represent a new therapeutic approach to treating the neurodegenerative disorder.

Scientists reveal role for lysosome transport in Alzheimer's disease progression

(Rockefeller University Press) Researchers from Yale University School of Medicine have discovered that defects in the transport of lysosomes within neurons promote the buildup of protein aggregates in the brains of mice with Alzheimer's disease. Show More Summary

The fractal zealots

Paul Alper points to this news report by Ian Sample, which goes: Psychologists believe they can identify progressive changes in work of artists who went on to develop Alzheimer’s disease The first subtle hints of cognitive decline may reveal themselves in an artist’s brush strokes many years before dementia is diagnosed, researchers believe... Show More Summary

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