Currently, no cure exists for Alzheimer's disease, the devastating neurological disease affecting more than 5 million Americans. But scientists are now reporting new progress on a set of compounds, initially developed for cancer treatment, that shows promise as a potential oral therapy for Alzheimer's. Their study appears in ACS' Journal of Medicinal Chemistry. read more
A type of immune cell widely believed to exacerbate chronic adult brain diseases, such as Alzheimer's disease and multiple sclerosis, can actually protect the brain from traumatic brain injury and may slow the progression of neurodegenerative diseases, according to research. Show More Summary
Roche’s Genentech unit just released a mid-stage study of a drug that seeks to slow the progression of Alzheimer’s by blocking the accumulation of a protein called amyloid beta. Like every other medicine that has attempted this approach – which remains the main one being pursued by drug companies to battle Alzheimer’s – the drug [...]
Frontotemporal dementia (FTD) is a cluster of progressive diseases that affect the regions of the brain that control personality, behavior, language, and decision-making. By Carole B. LarkinAlzheimer's Reading RoomAre you sure its Alzheimer's?...Show More Summary
While the drug, crenezumab, did not slow progression of the disease over all, at the highest doses it seemed to delay a decline in mental ability in patients with mild Alzheimer’s.
Researchers have conducted the first-ever analysis of clinical trials for Alzheimer's disease, revealing an urgent need to increase the number of agents entering the AD drug development pipeline and progressing successfully towards new therapy treatments.
Patients with Alzheimer's disease run a high risk of seizures. While the amyloid-beta protein involved in the development and progression of Alzheimer's seems the most likely cause for this neuronal hyperactivity, how and why this elevated activity takes place hasn't yet been explained – until now. read more
As my mother continued her decline from Alzheimer’s, it was disconcerting to ride the roller coaster of emotions. Wearing the daughter/caregiver hat I felt powerless to change the progression of her disease. By Elaine C PereiraAlzheimer's Reading Room As an Occupational herapist I believe it is. Show More Summary
His memory loss became apparent first. Like many people experiencing Alzheimer's in its early stages, my father began misplacing important objects and forgetting the names of people. As the disease progressed, his conversational skills...Show More Summary
The symptoms of dementia typically begin so mildly, and progress so slowly, that it’s easy to deny them until one day there may be a defining incident. Marie MarleyAlzheimer's Reading Room When a person begins to show signs of dementia, that person and their loved ones are sometimes in denial. Show More Summary
Famed cookbook author Paula Wolfert was diagnosed with Benson's syndrome (a variant of Alzheimer's) which has led her to swap exotic ingredients for foods that could help "stall the inevitable progression of her disease. She once wrote "volumes on preserved...
One of the most devastating forms of memory loss is Alzheimer's disease, an irreversible and progressive brain disorder that slowly destroys memory and thinking skills. +Alzheimer's Reading Room Subscribe to the Alzheimer's Reading Room...Show More Summary
Researchers here show an association between blood vessel stiffening and the deposition of ?-amyloid in people who have not yet developed Alzheimer's disease. In general we should not be surprised to see associations between different measurable aspects of aging, as aging is a global phenomenon resulting from a small number of root causes. Show More Summary
Researchers at the University of Texas Medical Branch at Galveston have discovered a way to potentially halt the progression of dementia caused by accumulation of a protein known as tau.Normally, tau protein is involved in microtubule formation, which acts as a brain cell's transportation system for carrying nutrients in and waste out. Show More Summary
A new clinical trial will soon begin testing whether early medical intervention in people at risk for Alzheimer's can slow down progression of disease pathology before symptoms emerge, as outlined in Science Translational Medicine. For...Show More Summary
A new clinical trial will soon begin testing whether early medical intervention in people at risk for Alzheimer's can slow down progression of disease pathology before symptoms emerge. As part of the overall prevention trial, neurodegenerative ethics experts will monitor how learning about their risk of developing Alzheimer's impacts trial participants.
Researchers at the University of Texas Medical Branch at Galveston have discovered a way to potentially halt the progression of dementia caused by accumulation of a protein known as tau. Normally, tau protein is involved in microtubule formation, which acts as a brain cell's transportation system for carrying nutrients in and waste out. Show More Summary
Two pivotal processes affected by copper may hasten the onset and progression of Alzheimer's. ? Dr Jeremy Dean is a psychologist and author of PsyBlog. His latest book is "Making Habits, Breaking Habits: How to Make Changes That Stick" Related...Show More Summary
Alzheimer's disease represents the most common form of dementia, with the early stages of the disease generally characterized with short term memory loss and learning difficulties that increase in severity as the patient progresses in age. Show More Summary
The progression of Alzheimer's may slow once symptoms appear and do significant damage, according to a study investigating an inherited form of the disease. Through an international study, researchers have found rapid neuronal damage begins 10 to 20 years before symptoms appear. Show More Summary