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Paralysed rats walk again after breakthrough surgery using stem cells from a human's mouth

Scientists have healed a rat's severed spinal cord. Stem cells from a human’s mouth were used in the process. Researchers hope to test the pioneering surgery on humans in the future. Seeing a rat scurry by would send many people running...Show More Summary

Crowding in the skin: Stem cells sense neighborhood density to make decisions

Human skin is a remarkable organ serving as a barrier protecting us from pathogens, toxic substances and others. Our skin needs to constantly renew throughout our lifetime as well as change its size to perfectly fit and cover the body. Show More Summary

Study Identifies Barriers to Transplant Therapy to Treat Multiple Myeloma Among Racial Minority Groups

A study by researchers at Mayo Clinic's campus in Jacksonville, Florida has found that barriers to patients receiving stem cell therapy as part of their treatment for multiple myeloma include income, education, insurance status and access to care at an academic center or facility that treats a high volume of patients.

New Technique Allows Mass Production of Bioengineered Liver Tissue

21 hours agoIndustries / Medical : medGadget

Researchers at Yokohama City University and Cincinnati Children’s Center for Stem Cell and Organoid Medicine have developed a large-scale method to produce bioengineered liver tissue from human induced pluripotent stem cells (iPSCs)....Show More Summary

Crowding in the skin

Stem cells sense neighbourhood density to make decisions on their behaviour

Cytotwister, A Unique 3D Stem Cell Bioreactor: Interview with Dr. Hsin-Hsin Shen of Industrial Technology Research Institute

Stem cells are up-and-coming therapies, and a major engineering problem has been scaling up the cell manufacturing to create enough cells for different therapeutic applications. Cytotwister, from the Industrial Technology Research Institute (ITRI) in Taiwan, makes a step towards solving that with a unique 3D stem cell bioreactor system that addresses common issues in stem […]

Low-Dose Treatment with Interleukin-2 Across Multiple Studies Shows Benefits in Chronic Graft-Versus-Host Disease

Daily low doses of the immune signaling protein interleukin-2 (IL-2) can safely benefit patients who develop chronic graft-versus-host disease following stem cell transplants, including particular benefit in pediatric patients in one small study, report scientists from Dana-Farber Cancer Institute.

Study explores use of checkpoint inhibitors after relapse from donor stem cell transplant

(Dana-Farber Cancer Institute) Immunotherapy agents known as checkpoint inhibitors have shown considerable promise in patients with hematologic cancers who relapse after a transplant with donor stem cells. Preliminary results from the...Show More Summary

Immunotherapy Drug for Rheumatoid Arthritis Nearly Eliminates Severe Acute Graft-Versus-Host Disease after Hematopoietic Stem Cell Transplant

Results from a phase 2 clinical trial, presented by Seattle Children's Research Institute at the 59th American Society of Hematology (ASH) Annual Meeting, show that the drug Abatacept (Orencia) nearly eliminated life-threatening severe acute graft-versus-host disease (GvHD) in patients receiving hematopoietic stem cell transplants.

OCDA obtains $7.8 million settlement against two Orange County companies accused of selling fetal tissue for profit

SANTA ANA – The Orange County District Attorney’s Office has obtained a $7.8 million settlement in a civil lawsuit against two Yorba Linda medical companies accused of illegally profiting from the sale fetal tissue and stem cells. Under the agreement filed Friday in Orange County Superior Court, DaVinci Biosciences and its sister company, DV Biologics, […]

Inhibiting TOR boosts regenerative potential of adult tissues

Adult stem cells replenish dying cells and regenerate damaged tissues throughout our lifetime. We lose many of those stem cells, along with their regenerative capacity, as we age. Working in flies and mice, researchers discovered that TOR, a nutrient sensing pathway which is central to the aging process, drives the loss of adult stem cells. Show More Summary

Common virus may help inform treatment planning for stem cell transplant patients

A genetic relationship has been found between the reactivation of the human cytomegalovirus and the onset of graft-versus-host disease (GVHD), a potentially deadly condition in which the immune system attacks healthy tissue following a bone marrow or stem cell transplant.

Novel harvesting method rapidly produces superior stem cells for transplantation

A new method of harvesting stem cells for bone marrow transplantation may make the donation process more convenient and less unpleasant for donors while providing cells that are superior to those acquired by current protocols.

Increased Autophagy Improves Stem Cell Activity and Restores Bone Loss in Mice

3 days agoHealth / Aging : Fight Aging

Researchers here provide evidence for increased autophagy, achieved via targeting mTOR to mimic some of the response to calorie restriction, to improve stem cell function in old mice. As a result some of the loss of bone mass and strength that occurs with age was reversed. Show More Summary

mTOR and the Age-Related Decline in Stem Cell Activity

3 days agoHealth / Aging : Fight Aging

As a companion piece to an earlier post on the relationship between the mechanistic target of rapamycin (mTOR) gene and cellular senescence in aging, you might take a look at the research here that investigates the relationship between mTOR and the characteristic decline in stem cell activity that occurs with advancing age. Show More Summary

#FiercePierce: 2-Year-Old Patient Beats Back Leukemia and Inspires Thousands of Potential Stem Cell Donors

2-year-old Children's Hospital Los Angeles patient Pierce Kelly beats leukemia thanks to a stem cell donor in France and inspires thousands of potential donors.

A common virus may help inform treatment planning for stem cell transplant patients

(Virginia Commonwealth University) a team of scientists from VCU Massey Cancer Center have shown a genetic relationship between the reactivation of the human cytomegalovirus and the onset of graft-versus-host disease (GVHD), a potentially deadly condition in which the immune system attacks healthy tissue following a bone marrow or stem cell transplant.

Research papers shed light on decade-long stem cell mystery

A series of studies led by Monash University researcher Associate Professor Jose Polo have this week shed light on vital, yet previously unclear, aspects of cell reprogramming.

Novel harvesting method rapidly produces superior stem cells for transplantation

(Massachusetts General Hospital) A new method of harvesting stem cells for bone marrow transplantation -- developed by a team of investigators from the Massachusetts General Hospital Cancer Center and the Harvard Stem Cell InstituteShow More Summary

3-D mini brains accelerate research for repairing brain function

Hospitals are making mini brains from human stem cells, putting researchers on a fast track to repair the nervous system after injury or disease of the brain and spinal cord. Researchers have developed a new system to reduce the time...Show More Summary

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