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The New York Stem Cell Foundation Annual Conference

(New York Stem Cell Foundation) NYSCF's 12th Annual Translational Stem Cell Research Conference convenes global leaders in translational stem cell and neuroscience research to present their latest work towards new treatments and cures for the most devastating diseases and injuries currently facing the world. Show More Summary

FDA-approved clinical trial tests stem cells to heal wounds

(Sanford Health/Sanford Research) Sanford Health is launching its second adipose-derived stem cell clinical trial -- this one to focus on non-healing leg wounds.

Reviewing Cdc42 as a Means to Make Hematopoietic Stem Cells Functionally Young

15 hours agoHealth / Aging : Fight Aging

Hematopoietic stem cells (HSCs), responsible for generating blood and immune cells, decline with age. This is one of the reasons why old immune systems suffer from a low rate of replacement of cells. For some years now, researchers have...Show More Summary

Stem cell platform sheds new light on beginnings of human development

Researchers at University of Toronto's Medicine By Design have engineered a new platform to study the earliest stages of human development in the lab, pulling back the curtain on key biological processes that until now have taken place inside the uterus, beyond the gaze of scientists.

Inflammation: Memory beyond immunity

2 days agoAcademics : Nature AOP

Epithelial stem cells maintain the skin's epidermis and promote wound healing in response to injury. Scientists from two fields discuss implications of the discovery that these stem cells harbour a memory of previous injuries, which enables skin to respond rapidly to subsequent assaults.

Inflammatory memory sensitizes skin epithelial stem cells to tissue damage

2 days agoAcademics : Nature AOP

After acute inflammation, epithelial stem cells retain a memory that accelerates restoration of the skin barrier during subsequent tissue damage, and this enhancement is dependent on the AIM2 inflammasome and its downstream effector...

German research advances in cancer and blood disorders reported in human gene therapy

(Mary Ann Liebert, Inc./Genetic Engineering News) Virotherapy capable of destroying tumor cells and activating anti-tumor immune reactions, and the use of engineered hematopoietic stem cells (HSCs) to deliver replacement genes that have the potential to cure blood diseases are among the key areas of gene therapy being advanced by German researchers.

Multiple Sclerosis: Oligodendrocytes from stemmcells

(Heinrich-Heine University Duesseldorf) A scientific collaboration between stem cell researchers of the Heinrich-Heine-University Duesseldorf, Germany, led by Prof. Patrick Küry (Neurology) and by Prof. James Adjaye (Stem Cell Research...Show More Summary

Parabiosis Restores Some Kidney Function in Aged Animals

2 days agoHealth / Aging : Fight Aging

In parabiosis studies, a young and old animal have their circulatory systems linked. This is shown to improve measures of aging in the old animal, such as regenerative capacity, stem cell activity, and so forth. There is considerable...Show More Summary

Mesenchymal Stem Cell Transplants Trialed as a Therapy for Age-Related Frailty

3 days agoHealth / Aging : Fight Aging

At least one group is running trials of stem cell transplants as a potential treatment for age-related frailty syndrome: the scope of the possible in the near term is to find way to incrementally improve the condition, not produce a sizable reversal, but that is an improvement over the current situation, given that there is no effective treatment. Show More Summary

Resolving traffic jams in human ALS motor neurons

(VIB (the Flanders Institute for Biotechnology)) A team of researchers at VIB and KU Leuven used stem cell technology to generate motor neurons from ALS patients carrying mutations in FUS. They found disturbed axonal transport in these motor neurons, but also identified genetic and pharmacological strategies that mitigate this defect.

Genomics researchers showcase their applications of Droplet Digital PCR at ASHG 2017 Annual Meeting

(Chempetitive Group) During the conference, researchers will discuss how Droplet Digital PCR helps them screen stem cells for harmful mutations as well as how Droplet Digital PCR provides early detection of transplant rejection and delivers absolute quantification of gene expression to investigate cancer.

Bolstering Fat Cells Offers Potential New Leukemia Treatment

Killing cancer cells indirectly by powering up fat cells in the bone marrow could help acute myeloid leukemia patients, according to a study from McMaster University's Stem Cell and Cancer Research Institute and published in Nature Cell Biology.

BrainStorm enrolls first patients in advanced ALS stem cell trial

TEL AVIV (Reuters) - BrainStorm Cell Therapeutics said the first patients have been enrolled in a late-stage trial of its treatment for amyotrophic lateral sclerosis (ALS) at Massachusetts General Hospital and UC Irvine Medical Center in California.

Stem Cells From Umbilical Cords of Newborn Babies Show Promise in Repairing Heart Damage

In a first-of-its-kind study published in Circulation Research, an American Heart Association journal, researchers from Universidad de los Andes in Chile found that stem cells derived from the umbilical cords of newborn babies may lead to repairs in damaged hearts and improvements in heart muscle. “We are encouraged by our findings because they could pave […]

USC team finds a potentially better way to treat liver cancer

A Keck School of Medicine of USC research team has identified how cancer stem cells survive. This finding may one day lead to new therapies for liver cancer, one of the few cancers in the United States with an incidence rate that continues to balloon.

3-D Packaging of DNA Regulates Cell Identity

A new study suggests that the ability of a stem cell to differentiate into cardiac muscle (and by extension other cell types) depends on what portions of the genome are available for activation, which is controlled by the location of DNA in a cell's nucleus.

3-D packaging of DNA regulates cell identity

(University of Pennsylvania School of Medicine) A new study suggests that the ability of a stem cell to differentiate into cardiac muscle (and by extension other cell types) depends on what portions of the genome are available for activation, which is controlled by the location of DNA in a cell's nucleus.

USC team finds a potentially better way to treat liver cancer

(University of Southern California) A USC research team has identified how cancer stem cells survive. This finding may one day lead to new therapies for liver cancer. James Ou and his colleagues found that mitophagy, the removal of damaged mitochondria, is a potential therapeutic target. Show More Summary

Swedish prosecutor says will not charge Italian stem cell surgeon

STOCKHOLM (Reuters) - Swedish prosecutors said on Thursday they were ending without charges an investigation into surgeon Paolo Macchiarini after finding no legal evidence he caused the death of three patients.

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