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Scientists create therapy-grade stem cells using new cocktail to reprogram adult cells

Researchers have developed a new cocktail that's highly effective at coaxing adult cells to become quality pluripotent stem cells (iPSCs). Using a new combination of reprogramming factors, they produced a higher quality result than the traditional formula. The new mix delivers fewer colonies of iPSCs, but 80% of them pass the toughest pluripotency test.

Scientists create therapy-grade stem cells using new cocktail to reprogram adult cells

Researchers at the Hebrew University of Jerusalem have developed a new cocktail that is highly effective at coaxing adult cells to become quality pluripotent stem cells. Regenerative medicine is a new and expanding area that aims to replace lost or damaged cells, tissues or organs through cellular transplantation. Show More Summary

Stem Cells: Plenty of Hope, but Halting Progress

yesterdayHealth : NYT: Health

Though enthusiasm for potential advances in disease and injury treatments often outstrips the science, thousands of clinical trials are now underway to figure out how to best use stem cells.

Spinal Cord Injury and Stem Cell Therapy

2 days agoOdd : It Thing!

Stem cells have the unique ability to divide and replicate into various types of tissues for the purpose of repairing and replacing tissue damaged or destroyed by disease processes or injury. Stem cells may also replicate and remain stem cells without having a specialized function. The unusual properties of these cells, which are present in [...]

USC researchers discover the healing power of 'rib-tickling'

Unlike salamanders, mammals can't regenerate lost limbs, but they can repair large sections of their ribs. In a new study in the Journal of Bone and Mineral Research, a team directed by USC Stem Cell researcher Francesca Mariani takes a closer look at rib regeneration in both humans and mice. read more

Re-expression of an embryonic signaling pathway in Melanoma utilizes different receptors

Metastatic melanoma is a highly aggressive skin cancer whose incidence is on the rise at an alarming rate. Research has revealed that metastatic tumor cells share similar signaling pathways with embryonic stem cells to sustain plasticity and growth. Show More Summary

Stem Cell Transplant First

NeurologicaBlog is very meta. I like to not only communicate science, but explore how best to communicate science, including thinking about how to communicate the need to think about thinking. (Cue the endless meta-regression.) For example, there is often much to criticize about how science news is reported in the general media. Part of the [...]

FASTER, PLEASE: Japanese woman is first recipient of next-generation stem cells: Surgeons implante…

FASTER, PLEASE: Japanese woman is first recipient of next-generation stem cells: Surgeons implanted retinal tissue created after reverting the patient’s own cells to ‘pluripotent’ state.

Faster way found to create insulin-producing cells

A study highlighting a protocol to convert stem cells into insulin-producing cells has been published by researchers. The new procedure could be an important step in the fight against type 1 diabetes. The protocol can turn stem cells into reliable, insulin-producing cells in about six weeks, far quicker than the four months it took using previous methods.

Woman Receives First Stem Cell Therapy Using Her Own Skin Cells

5 days agoHealth : Healthland

A Japanese woman is the first to receive retinal cells made from her own skin cells

Scientists revert human stem cells to pristine state

Researchers have resolved a long-standing challenge in stem cell biology by successfully 'resetting' human pluripotent stem cells to a fully pristine state, at a point of their greatest developmental potential.

Neurochemical imbalance in schizophrenia discovered

Using human induced pluripotent stem cells (hiPSCs), researchers have discovered that neurons from patients with schizophrenia secrete higher amounts of three neurotransmitters broadly implicated in a range of psychiatric disorders.

Breakfast Wrap: Thursday Night's Top Stories

This Could Be A First Glimpse Of Windows 9 Yes, there is a Start button. Induced Stem Cells Will Be Tested On Humans For The First Time Macular degeneration patients are first on the list. This Universal Mount Will Let You Use Any Phone On Your Handlebars And it’s virtually thief-proof by design. Show More Summary

Diabetes researchers find faster way to create insulin-producing cells

University of British Columbia, in collaboration with BetaLogics Venture, a division of Janssen Research & Development, LLC, has published a study highlighting a protocol to convert stem cells into insulin-producing cells. The new procedure...Show More Summary

A non-toxic strategy to treat leukemia

A study comparing how blood stem cells and leukemia cells consume nutrients found that cancer cells are far less tolerant to shifts in their energy supply than their normal counterparts. The results suggest that there could be ways to target leukemia metabolism so that cancer cells die but other cell types are undisturbed. read more

Scientists discover neurochemical imbalance in schizophrenia

Using human induced pluripotent stem cells (hiPSCs), researchers at Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California, San Diego have discovered that neurons from patients with schizophrenia secrete higher amounts of three neurotransmitters broadly implicated in a range of psychiatric disorders. read more

Scientists Discover Neurochemical Imbalance in Schizophrenia

Using human induced pluripotent stem cells (hiPSCs), researchers at Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California, San Diego have discovered that neurons from patients with schizophrenia secrete higher amounts of three neurotransmitters broadly implicated in a range of psychiatric disorders.

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