If you've ever been hit with an 'intestinal bug', you've felt the effects of infectious microbes on your digestive system. But scientists don't fully understand what's going on in gut infections like that - or in far more serious ones. Now, a team of scientists will tackle that issue in a new way.
In an effort to grow placenta cells to better study the causes of pre-eclampsia, researchers serendipitously discovered a previously unknown form of human embryonic stem cell.
Researchers are optimistic that a stem cell treatment they successfully tested in rats will slow or reverse the effects of early-stage age-related macular degeneration in humans.
Fifteen years after California entrepreneur and downhill ski champion Mike May underwent a pioneering stem cell procedure, researchers investigate how functional his vision is. "With sight-restoration procedures becoming more developed,...Show More Summary
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Age-related macular degeneration has a fairly direct relationship to the accumulation of a mix of metabolic wastes called lipofuscin in long-lived retinal cells. There are other contributing causes, but that is an important one. Cell...Show More Summary
A gene critical to controlling the body's ability to create blood cells and immune cells from blood-forming stem cells -- known as hematopoietic stem cells -- has been discovered by researchers. Along with helping scientists better understand...Show More Summary
An injection of stem cells into the eye may soon slow or reverse the effects of early-stage age-related macular degeneration, according to new research from scientists at Cedars-Sinai. Currently, there is no treatment that slows the progression of the disease, which is the leading cause of vision loss in people over 65.
Research led by the University of Michigan Life Sciences Institute has identified a gene critical to controlling the body's ability to create blood cells and immune cells from blood-forming stem cells--known as hematopoietic stem ce...
Children with 'bubble boy disease' who undergo gene therapy have fewer infections and hospitalizations than those receiving stem cells from a partially matched donor, new research suggests. Children with SCID-X1 are born with a genetic defect that prevents them from developing a normal immune system. Show More Summary
Cancerous tumors have the ability to evade targeted therapies by activating alternative pathways. Tumors also contain cancer stem cells, believed responsible for metastasis and drug resistance. Now scientists in the Cancer Research Institute at Beth Israel Deaconess Medical Center have identified a drug target that addresses both of these challenges.
New research reports that children with "bubble boy disease" who undergo gene therapy have fewer infections and hospitalizations than those receiving stem cells from a partially matched donor. The research is the first to compare outcomes...Show More Summary
Quick health update: the stem cell collection went swimmingly this week. We now have loads and loads of fresh stem cells frozen and waiting for me when I go back for the final stage of chemotherapy. I got home yesterday, and at the moment...Show More Summary
Our tissue's inability to repair itself as we grow older is thought to correlate with the decline in the presence of stem cells. So it follows that if stem cell function can be preserved beyond the norm, it could have implications for the aging process and adverse effects of tissue degeneration, such as cancer. Show More Summary
Scientists show mice injected with healing hydrogel made of fibrin and amniotic stem cells grow more robust networks of blood vessels than those injected with fibrin-only hydrogel.
The usual model for presently available stem cell therapies is for stem cells to be taken from the patient, often from bone marrow, greatly expanded in number, and reintroduced into target tissues. This has been shown over the past decade...Show More Summary
Using induced pluripotent stem cells (iPSCs), a team led by Mount Sinai researchers has gained new insight into genetic changes that may turn a well known anti-cancer signaling gene into a driver of risk for bone cancers.
Scientists use stem cells derived from amniotic fluid to promote the growth of robust, functional blood vessels in healing hydrogels. The researchers combined versatile amniotic stem cells with injectable hydrogels used as scaffolds in regenerative medicine and proved they enhance the development of vessels needed to bring blood to new tissue and carry waste products away.
Stem cell activity declines with age, an evolutionary trade-off that reduces the risk of death by cancer at the cost of increasing frailty and a slower death due to failure of tissue maintenance. This is just one of the many contributing factors that together determine the present human life span and the course of failing health for most people. Show More Summary
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