Mice lacking p21 can regenerate small wounds without scarring, something that is not normally possible in adult mammals. Separately, SDF-1 has been identified as a signal to recruit and activate stem cells, and efforts are underway build regenerative therapies on this basis. Show More Summary
The press here reports on the positive results of a recent small trial of the introduction of stem cells during bypass surgery for heart attack survivors. Stem cell therapies have over the past decade demonstrated highly variable outcomes in patients, and the methodology of delivery has been shown to be very important. Show More Summary
Joy Victory is deputy managing editor of HealthNewsReview.org. She tweets as @thejoyvictory. Last week about a dozen different news outlets reported on a paper in the Proceedings of the National Academy of Sciences showing that researchers...Show More Summary
The stem cells responsible for muscle growth and regeneration are perhaps the best studied of such populations. It seems that most of the new and interesting insights into the nuts and bolts of stem cell biology are coming from this part of the field, in any case. Show More Summary
A key gene enables the repair of injured muscle throughout life. This is the finding of a study in mice led by researchers at NYU Langone Medical Center and the University of Colorado at Boulder, and published online July 21 in CellShow More Summary
Prof. Fiona Doetsch's research team at the Biozentrum, University of Basel, has discovered that the choroid plexus, a largely ignored structure in the brain that produces the cerebrospinal fluid, is an important regulator of adult neural stem cells. Show More Summary
Researchers at Hospital for Special Surgery have launched a study to determine if a treatment using stem cells could help people with painful knee arthritis. To evaluate safety and efficacy, investigators are currently recruiting patients with osteoarthritis, which comes from wear and tear on a joint.
It's no secret that being overweight increases the chances of negative outcomes for cancer patients and now researchers from the University of Colorado Cancer Center may have uncovered a possible explanation for this. They found that...Show More Summary
Across many cancer types, obese patients fare worse than leaner patients. Now a University of Colorado Cancer Center study published in the journal Cell Stem Cell offers a compelling hypothesis why: researchers found that leukemia stem...Show More Summary
A new study offers a compelling hypothesis explaining poor prognosis for obese cancer patients: researchers found that leukemia stem cells "hide" in fatty tissue, even transforming this tissue in ways that support their survival when challenged with chemotherapy.
WELL, THIS IS THE 21ST CENTURY, YOU KNOW: Cartilage grown from stem cells could replace hip implants. “We’ve developed a way to resurface an arthritic joint using a patient’s own stem cells to grow new cartilage, combined with gene therapy to release anti-inflammatory molecules to keep arthritis at bay,” said Farshid Guilak, professor of orthopedic […]
In a scene from the Absolutely Fabulous movie, Eddy wonders why her treatment with stem cells from a 2-year-old child’s blood hasn’t worked magic on her face, while Patsy injects filler directly into hers.At the film’s New York premiere on Monday, the two stars said that in real life they ... More »
Certain questions in modern cell biology can only be answered by specifically observing the fate of individual cells. For example, researchers are interested in how stem cells develop into other cell types. Since in some cases such processes...Show More Summary
Researchers describe how it may be possible to use a patient's own stem cells and a 3-D, synthetic scaffold to grow new hip joint-shaped cartilage.
Biologists have found that a protein that plays a key role in the lives of stem cells can bolster the growth of damaged muscle tissue, a step that could potentially contribute to treatments for muscle degeneration caused by old age and diseases such as muscular dystrophy.
The virus may rely on particular receptors to infect neural stem cells—but scientists still have more questions than answers.
Cedars-Sinai scientists are seeking to build an improved stem-cell model of amyotrophic lateral sclerosis (ALS) to accelerate progress toward a cure for the devastating neurological disorder. Their findings demonstrate that current models can be enhanced by the aging of motor neurons to show how ALS damages cells later in life.
0000-0002-8996-1849The landscape of science is always shifting and in the last ten years we’ve seen a significant change brought by revolutionary discoveries like the powerful induced pluripotent stem cell (iPSC) and CRISPR/Cas9 technologies. Since then
With a goal of treating worn, arthritic hips without extensive surgery to replace them, scientists have programmed stem cells to grow new cartilage on a 3-D template shaped like the ball of a hip joint. What's more, using gene therapy,...Show More Summary