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Vitamin C regulates stem cell function, curbs leukemia development, scientists discover

Not much is known about stem cell metabolism, but a new study from the Children's Medical Center Research Institute at UT Southwestern has found that stem cells take up unusually high levels of vitamin C, which then regulates their function and suppresses the development of leukemia.

CRI scientists discover vitamin C regulates stem cell function, curbs leukemia development

(UT Southwestern Medical Center) Not much is known about stem cell metabolism, but a new study from the Children's Medical Center Research Institute at UT Southwestern has found that stem cells take up unusually high levels of vitamin C, which then regulates their function and suppresses the development of leukemia.

CRI Scientists Discover Vitamin C Regulates Stem Cell Function and Suppresses Leukemia Development

Not much is known about stem cell metabolism, but a new study from the Children's Medical Center Research Institute at UT Southwestern (CRI) has found that stem cells take up unusually high levels of vitamin C, which then regulates their function and suppresses the development of leukemia.

Eating habits affect skin's protection against sun

(UT Southwestern Medical Center) Sunbathers may want to avoid midnight snacks before catching some rays.

Clinical trial eligibility criteria a growing obstacle

(UT Southwestern Medical Center) Despite a decade-long call for simplification of clinical trials, the number of criteria excluding patients from participating in clinical trials for lung cancer research continues to rise.

UT Southwestern ranks No. 5 in the world in research that drives further innovation

UT Southwestern Medical Center ranks fifth in the world in the number of published research articles cited as significant sources in third-party patent applications. This new measurement is a way to evaluate an institution's impact and...Show More Summary

UT Southwestern ranked No. 1 hospital in Dallas-Ft. Worth by U.S. News & World Report

UT Southwestern Medical Center is the No. 1-ranked hospital in Dallas-Fort Worth, second in Texas, and nationally ranked among the top 50 programs in six clinical specialty areas, according to U.S. News & World Report's annual Best Hospitals listings released today.

Magnetic Fields to Destroy Bacteria on Artificial Joints

Scientists at UT Southwestern Medical Center have developed a new technique using high-frequency alternating magnetic fields to heat artificial joints in the body and destroy bacterial films on their surfaces. Bacterial infections on artificial joints used in knee and hip replacements are a common and serious complication. The bacteria tend to form slimy films on the […]

Black Men Have Lowest Survival Rates Among Patients with Anal Cancer

As published in JNCCN - Journal of the National Comprehensive Cancer Network, researchers at UT Southwestern Medical Center found significant racial and gender-based disparities in outcomes among patients with locoregional anal canc...

Magnetic fields turn up the heat on bacterial biofilms

(UT Southwestern Medical Center) A short exposure to an alternating magnetic field might someday replace multiple surgeries and weeks of IV antibiotics as treatment for stubborn infections on artificial joints, new research suggests...

Calcium in arteries influences heart attack risk

(UT Southwestern Medical Center) Patients without calcium buildup in the coronary arteries had significantly lower risk of future heart attack or stroke despite other high risk factors such as diabetes, high blood pressure, or bad cholesterol levels, new research from UT Southwestern cardiologists shows.

First-in-class drug holds promise for therapy-resistant breast cancer

(UT Southwestern Medical Center) UT Southwestern Simmons Cancer Center researchers have shown that a first-in-class molecule can prevent breast cancer growth when traditional therapies stop working.

Study: Muscle, not brain, may hold answers to some sleep disorders

(UT Southwestern Medical Center) Scientists exploring the brain for answers to certain sleep disorders may have been looking in the wrong place.

UT Southwestern finds link between backup immune defense, mutation seen in Crohn's disease

(UT Southwestern Medical Center) Genes that regulate a cellular recycling system called autophagy are commonly mutated in Crohn's disease patients, though the link between biological housekeeping and inflammatory bowel disease remained a mystery.

CRI Scientists Increase Our Understanding of the Genetic Basis of Neuropsychiatric Disorders

A study by scientists at the Children's Medical Center Research Institute at UT Southwestern (CRI) is providing insight into the genetic basis of neuropsychiatric disorders. In this research, the first mouse model of a mutation in the ARID1B gene was created and then used to show that growth hormone treatments reverse some manifestations of the mutation.

CRI scientists provide insight into genetic basis of neuropsychiatric disorders

(UT Southwestern Medical Center) A study by scientists at the Children's Medical Center Research Institute at UT Southwestern (CRI) is providing insight into the genetic basis of neuropsychiatric disorders. In this research, the first...Show More Summary

Hamon Center Researcher to Lead International 'Dream Team' on Regenerative Heart Medicine

Regeneration specialists at UT Southwestern Medical Center will join a "dream team" of international researchers seeking ways to regenerate damaged heart muscle in heart failure patients.

Researchers report chemical reaction with potential to speed drug development

(UT Southwestern Medical Center) Chemists have long sought to develop new reactions for the direct conversion of simple hydrocarbon building blocks into valuable materials such as pharmaceuticals in a way that dependably creates the same chemical bonds and orientations.

Combo immunotherapy may herald new standard of care for kidney cancer

(UT Southwestern Medical Center) Combination therapy with two immunotherapy drugs produces an unprecedented doubling of response rates from 20 percent to 40 percent, a new study shows.

Possible Early Diagnosis of Autism Spectrum Disorder

Measuring a set of proteins in the blood may enable earlier diagnosis of autism spectrum disorder (ASD), according to a study from the Peter O'Donnell Jr. Brain Institute at UT Southwestern Medical Center.

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