(UT Southwestern Medical Center) A gene controlling our biological clocks plays a vital role in regulating human-specific genes important to brain evolution. The findings from the O'Donnell Brain Institute open new paths of research into how CLOCK proteins produced by the CLOCK gene affect brain function and the processes by which neurons find their proper place in the brain.
(UT Southwestern Medical Center) UT Southwestern Medical Center researchers have identified a chemical that suppresses the lethal form of a parasitic infection caused by roundworms that affects up to 100 million people and usually causes only mild symptoms.
Regenerative medicine researchers at UT Southwestern Medical Center developed an improved and simplified gene-editing technique using CRISPR/Cas9 tools to correct a common mutation that causes Duchenne muscular dystrophy.
UT Southwestern Medical Center researchers have developed a method to map protein changes that occur in different subtypes of breast cancer cells in response to DNA damage from a new class of chemotherapy drugs.
(UT Southwestern Medical Center) UT Southwestern researchers have identified a major mechanism by which obesity causes type 2 diabetes, which is a common complication of being overweight that afflicts more than 30 million Americans and over 400 million people worldwide.
CHICAGO - School-age football players with a history of concussion and high impact exposure undergo brain changes after one season of play, according to two new studies conducted at UT Southwestern Medical Center in Dallas and Wake Forest University in Winston-Salem and presented today at the annual meeting of the Radiological Society of North America (RSNA).
(UT Southwestern Medical Center) Researchers found that conditional deletion of Sox2 -- the gene encoding the SOX2 stem cell transcription factor -- and the associated dampening of astrocyte reactivity appear to promote functional recovery, including behavioral recovery, after traumatic brain injury, said Dr. Zhang, a W.W. Caruth, Jr. Scholar in Biomedical Research.
Heart attack and stroke patients without medical insurance face "devastating" health care costs that can bankrupt them, research from UT Southwestern and other centers shows.
Dr. Arthur Hong, Assistant Professor of Internal Medicine and Clinical Sciences at UT Southwestern Medical Center, has been selected as recipient of the Texas Health Resources Clinical Scholar Award for his research into how to improve the cost, quality, and delivery of health care.
(UT Southwestern Medical Center) Scientists are finding more evidence that commonly prescribed antidepressants aren't effective in people battling both depression and a chronic medical disease, raising a critical question of whether doctors should enact widespread changes in how they treat millions of depressed Americans.
UT Southwestern Medical Center researchers today published a 3-D atomic structure of the ion channel found in mammals that is implicated in a rare, inherited neurodegenerative disease in humans. The work marks the first such structure determined using the university's $17 million cryo-electron microscopy (cryo-EM) facility that opened last year.
UT Southwestern Medical Center researchers today published a 3-D atomic structure of the ion channel found in mammals that is implicated in a rare, inherited neurodegenerative disease in humans.
(UT Southwestern Medical Center) Scientists at the Children's Medical Center Research Institute at UT Southwestern (CRI) have discovered that lactate provides a fuel for growing tumors, challenging a nearly century-old observation known as the Warburg effect.
(UT Southwestern Medical Center) Individuals with certain types of bacteria in their gut may be more likely to respond well to cancer immunotherapy, researchers at the Harold C. Simmons Comprehensive Cancer Center found in a study of patients with metastatic melanoma.
(UT Southwestern Medical Center) Research led by Dr. Carlos Arteaga, Director of the Harold C. Simmons Comprehensive Cancer Center, has identified potential targets for treatment of triple negative breast cancer, the most aggressive form of breast cancer.
(UT Southwestern Medical Center) New research by UT Southwestern cardiologists shows that people of South Asian descent with a family history of coronary heart disease are significantly more likely to have high levels of calcium buildup in their arteries - an indicator of higher risk for heart attacks.
Texas Health Resources and UT Southwestern Medical Center joined today with Frisco city leaders to kick off a construction project that will bring an acute care hospital and multispecialty clinic complex to this rapidly growing part of Collin County.
(UT Southwestern Medical Center) UT Southwestern Medical Center researchers report for the first time that tumors stressed by cancer immunotherapy release their mitochondrial DNA into nearby immune cells, triggering a host alert sys...
UT Southwestern Medical Center researchers report for the first time that tumors stressed by cancer immunotherapy release their mitochondrial DNA into nearby immune cells, triggering a host alert system.
(UT Southwestern Medical Center) Scientists from the Children's Medical Center Research Institute at UT Southwestern have developed an innovative system to identify and characterize the molecular components that control the activities of regulatory DNA sequences in the human genome.