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Weight flux alters molecular profile, Stanford-led study finds

The human body undergoes dramatic changes during even short periods of weight gain and loss, according to a study led by researchers at the Stanford University School of Medicine. As people pack on pounds or shed excess weight, they exhibit notable changes in their microbiome, cardiovascular system, immune system and levels of gene expression, the study found.

How Your Brain Remembers What You Had for Dinner Last Night

Confirming earlier computational models, researchers at University of California San Diego and UC San Diego School of Medicine, with colleagues in Arizona and Louisiana, report that episodic memories are encoded in the hippocampus of the human brain by distinct, sparse sets of neurons.

How your brain remembers what you had for dinner last night

(University of California - San Diego) Confirming earlier computational models, researchers at University of California San Diego and UC San Diego School of Medicine, with colleagues in Arizona and Louisiana, report that episodic memories are encoded in the hippocampus of the human brain by distinct, sparse sets of neurons.

Researchers develop swallowable test to detect pre-cancerous Barrett's esophagus

(Case Western Reserve University) Investigators at Case Western Reserve University School of Medicine and University Hospitals Cleveland Medical Center have developed a simple, swallowable test for early detection of Barrett's esophagus that offers promise for preventing deaths from esophageal adenocarcinoma.

New research could significantly accelerate drug discovery

(University of Maryland School of Medicine) Many drugs work by inhibiting protein enzymes associated with a particular disease. Unfortunately, the same drugs can inhibit protein enzymes unrelated to the disease, resulting in harmful side effects. Show More Summary

Memory loss from West Nile virus may be preventable

(Washington University School of Medicine) More than 10,000 people in the United States are living with memory loss and other persistent neurological problems that occur after West Nile virus infects the brain. Now, a new study in mice...Show More Summary

Penn Medicine Orthopaedics and Princeton Orthopedic Associates forge strategy

(University of Pennsylvania School of Medicine) In continued collaboration, Penn Medicine and Princeton Orthopedic Associates formalize their relationship under the Penn Medicine Orthopaedic Specialty Network

Insurance company requirements place heavy administrative burden on physicians seeking to prescribe new cholesterol-lowering drugs

(University of Pennsylvania School of Medicine) A rare glimpse into the prior authorization requirements implemented by public and private insurance providers across the country has found substantial administrative burden for a new class of medications for patients with high cholesterol that places them at high risk for heart attack or stroke, according to new research.

Penn researchers identify new treatment target for melanoma

(University of Pennsylvania School of Medicine) Researchers in the Perelman School of Medicine at the University of Pennsylvania have identified a new therapeutic target for the treatment of melanoma. For decades, research has associated female sex and a history of previous pregnancy with better outcomes after a melanoma diagnosis. Show More Summary

Pediatric physician-scientists struggle for funding

(Washington University in St. Louis) A new, multicenter study that included Washington University School of Medicine in St. Louis has found that most NIH grants awarded to researchers in pediatrics during the past five years have been limited to physicians in senior positions at a small number of institutions. Show More Summary

Pediatric Physician-Scientists Struggle for Funding

A new, multicenter study that included Washington University School of Medicine in St. Louis has found that most NIH grants awarded to researchers in pediatrics during the past five years have been limited to physicians in senior positions at a small number of institutions. Show More Summary

UNC Expert Publishes Commentary About Recent Change in Donor Lung Allocation Policy

Dr. Thomas Egan of the University of North Carolina School of Medicine says that a recent change in donor lung allocation policy was long overdue. However, because the change happened over the Thanksgiving holiday weekend in response to litigation, it came as a "tsunami" that was "sudden, unexpected, and may have huge consequences."

Scholars develop new technology to decode gene transcription facilitating discovery of targeted therapy drugs

A research team from the School of Chinese Medicine (SCM) of Hong Kong Baptist University (HKBU) has developed the world's first model framework and "LogicTRN" algorithm to accurately establish a gene regulatory route to analyse theShow More Summary

Penn Researchers Identify New Treatment Target for Melanoma

Researchers in the Perelman School of Medicine at the University of Pennsylvania have identified a new therapeutic target for the treatment of melanoma. For decades, research has associated female sex and a history of previous pregnancy with better outcomes after a melanoma diagnosis. Show More Summary

Philip Pumerantz, university founder who helped resurrect osteopathic medicine, dies at 85

Philip Pumerantz, a former high teacher who helped resurrect the once-maligned practice of osteopathic medicine in California by founding what’s now a bustling medical school, has died at his home in Upland. Pumerantz, who was one of the longest-serving university presidents in the country when...

Past exposures shape immune response in pediatric acute respiratory infections

(University of Pennsylvania School of Medicine) By analyzing immune cells of children who came to the emergency department with flu symptoms, researchers found that the suite of genes these early-response cells expressed was shaped by factors such as age and previous exposures to viruses. Show More Summary

Researcher discovers commonalities in brains of people with HD and PD

(Boston University School of Medicine) A new study strongly suggests that the brains of people who have died of Huntington's disease (HD) and Parkinson's disease (PD) show a similar response to a lifetime of neurodegeneration, despite being two very distinct diseases.

Researchers Discover Faster, More Effective Way to Harvest Blood Stem Cells for Bone Marrow Donation

A multi-institutional research team led by Indiana University School of Medicine scientists has developed a new way to harvest blood stem cells for bone marrow donation that is faster and more effective than the current standard of care.

Researchers map druggable genomic targets in evolving malaria parasite

(University of California - San Diego) Researchers at University of California San Diego School of Medicine, with colleagues across the country and around the world, have used whole genome analyses and chemogenetics to identify new drug...Show More Summary

Researchers Map Druggable Genomic Targets in Evolving Malaria Parasite

Researchers at University of California San Diego School of Medicine, with colleagues across the country and around the world, have used whole genome analyses and chemogenetics to identify new drug targets and resistance genes in 262 parasite cell lines of Plasmodium falciparum -- protozoan pathogens that cause malaria -- that are resistant to 37 diverse antimalarial compounds.

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