Trend Results : Wellcome Trust

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Vulnerabilities of leukemia cells revealed using genome editing technique

(Wellcome Trust Sanger Institute) Researchers from the Wellcome Trust Sanger Institute and their collaborators have adapted a CRISPR gene editing technique and used it to find new therapeutic targets for acute myeloid leukemia (AML)....Show More Summary

International Human Cell Atlas Initiative

(Wellcome Trust Sanger Institute) The first project of its kind, as ambitious as the Human Genome Project, the Human Cell Atlas aims to chart the types and properties of all human cells, across all tissues and organs, to build a reference...Show More Summary

Health research: Africa–India health-science partnerships

last monthAcademics : Nature

Africa and India have common problems of communicable and non-communicable diseases, high maternal and child mortality, and weak health-delivery systems. Together with other funders, the Wellcome Trust is supporting capacity-building and innovation in health research in both regions, through the Alliance for Accelerating Excellence in

Study reveals how ionising radiation damages DNA and causes cancer

(Wellcome Trust Sanger Institute) For the first time, researchers from the Wellcome Trust Sanger Institute and their collaborators have been able to identify in human cancers two characteristic patterns of DNA damage caused by ionizing radiation. Show More Summary

Wellcome Trust: Report released on antibiotic resistance

2 months agoAcademics : Nature

The Wellcome Trust today releases a report to inform the United Nations General Assembly's High-level Meeting on Antimicrobial Resistance later this month (see The report distils the findings of an international summit of researchers, policymakers and multilateral institutions that met in London in

New study shows esophageal cancers driven by 'marginal gain' rather than speed

Wellcome Trust Sanger Institute scientists have shown that unexpectedly, oesophageal cancer cells do not divide faster than their normal neighbours. But unlike normal cells, the tumour cells produce slightly more dividing daughter cells...Show More Summary

The Joy of Pronking

Eadweard Muybridge's study of a deer in motion. (Photo: Wellcome Trust V0048764/CC BY 4.0) The other day, I was driving along a road in upstate New York when I saw a deer. This isn’t an unusual sight in itself, but this fawn, young enough...Show More Summary

New intellectual disability syndrome caused by genetic damage to single gene

Scientists at the Wellcome Trust Sanger Institute and Max Planck Institute for Psycholinguistics have found a gene responsible for an intellectual disability disorder and proven how it works. The research, published in the American Journal of Human Genetics, details the role of a gene called BCL11A in a new intellectual disability syndrome. read more

Why the new Wellcome Trust open review journal may be the science publishing future

John Bohannan in Science writes one of many stories about the Wellcome Trust establishing a new open access journal, in which peer review follows the posting of preprints: “U.K. research charity will self-publish results from its grantees”. Normally, peer review is anonymous and happens before publication of a paper. Show More Summary

Red hair gene variation drives up skin cancer mutations

For the first time, researchers at the Wellcome Trust Sanger Institute and University of Leeds have proved that gene variants associated with red hair, pale skin and freckles are linked to a higher number of genetic mutations in skin cancers. Show More Summary

Early screening spots emergency workers at greater risk of mental illness

Emergency services workers who are more likely to suffer episodes of mental ill health later in their careers can be spotted in the first week of training. That's the conclusion of a Wellcome Trust funded study carried out with trainee...Show More Summary

Sanger Institute: Landmark study shows AML is at least 11 different diseases

Scientists at the Wellcome Trust Sanger Institute and their international collaborators have shown that Acute Myeloid Leukaemia (AML) is not a single disorder, but at least 11 different diseases, and that genetic changes explain differences in survival among young AML patients. Show More Summary

New safety and efficacy evidence for mitochondrial donation revealed

A new IVF-based technique is likely to lead to normal pregnancies and reduce the risk that babies born will have mitochondrial disease, according to researchers at the Wellcome Trust Centre for Mitochondrial Disease at Newcastle University. Published...Show More Summary

How Wellcome and Gates charities profit from helping biotech

By Ben Hirschler LONDON (Reuters) - The Wellcome Trust medical charity is to profit from U.S. approval of a new diagnostic cancer test, the first commercial product funded by the organization since the sale of its pharmaceuticals business to Glaxo in 1995. Show More Summary

Bugs as drugs

Scientists at the Wellcome Trust Sanger Institute have grown and catalogued more than 130 bacteria from the human intestine according to a study published in Nature today (Wednesday May 4, 2016). read more

Clinical trial for experimental Ebola drug publishes results

Results of the Wellcome Trust funded trial of the experimental anti-Ebola drug TKM-130803 have been published today (April 19) in PLOS Medicine. Using a novel approach designed to get rapid indications of a drug's effectiveness, the trial showed that at the dose given the drug did not improve survival compared to historic controls. read more

Bioethicists Will Explore the Issues and Lessons of the Zika Crisis

With funding from the Wellcome Trust, an interdisciplinary team of scholars will focus on issues of ethics and research in pregnancy and women of reproductive age, beginning with the current Zika context and later expanding to general public health research.

Test run finds no cancer risk from stem cell therapy

Therapeutic stem cells can be made without introducing genetic changes that could later lead to cancer, a study in PLOS Genetics has found. The discovery, made by researchers at the Wellcome Trust Sanger Institute, is a boost for scientists...Show More Summary

British Museum welcomes new Director of Scientific Research

7 months agoArts : Artdaily

The British Museum welcomes Professor Carl Heron as the new Director of Scientific Research. He will lead the Museum?s renowned team of scientists under the new Department of Scientific Research, supported by the Wellcome Trust, and look to shape the scientific research programme for the future. Show More Summary

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