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New chlamydia drug targets discovered using CRISPR and stem cells

(Wellcome Trust Sanger Institute) Scientists at the Wellcome Trust Sanger Institute and their collaborators at the University of British Columbia have created an innovative technique for studying how chlamydia interacts with the human immune system. The results, reported today (April 25) in Nature Communications, identify novel drug targets for the sexually transmitted disease.

Genetics and environment combine to give everyone a unique sense of smell

(Wellcome Trust Sanger Institute) Researchers from the Wellcome Trust Sanger Institute and their collaborators have shown that receptors in the noses of mice exposed to certain smells during life are different to genetically similar mice that lived without those smells. Show More Summary

European Commission May Join Gates Foundation And Wellcome Trust In Becoming An Open Access Publisher

2 weeks agoIndustries / Law : Techdirt

Open access isn't a new idea -- the term was first defined back in 2002, and arguably the first examples go back even further to the founding of arXiv.org in 1991 (pdf). And yet progress towards making all academic knowledge freely available...Show More Summary

New stem cell method produces millions of human brain and muscle cells in days

(Wellcome Trust Sanger Institute) Wellcome Trust Sanger Institute scientists and their collaborators at the University of Cambridge have created a new technique that simplifies the production of human brain and muscle cells -- allowing millions of functional cells to be generated in just a few days. Show More Summary

Novel genes identified that help suppress prostate and other cancers

(Wellcome Trust Sanger Institute) New genes which help prevent prostate, skin and breast cancer development in mice have been discovered by researchers at the Wellcome Trust Sanger Institute and their collaborators. The study identified...Show More Summary

1 in 5 breast cancer patients could benefit from existing treatment, genetic study reveals

(Wellcome Trust Sanger Institute) Researchers from the Wellcome Trust Sanger Institute and their collaborators have discovered that a greater number of breast cancers are genetically similar to rarer cases with faulty BRCA1 or BRCA2 genes. Show More Summary

The Wellcome image awards 2017: the shortlist of the year’s best science visions

The organiser of the Wellcome Trust’s awards for outstanding scientific imagery explains why she believes that pictures really are worth a thousand words With its huge eyes, comical name and diminutive size, Mark R Smith’s image of a baby Hawaiian bobtail squid can’t help but raise a smile. Show More Summary

Plague game up for health trust prize

Winter Hall in the running as Wellcome Trust announces six finalists for its Developing Beyond prize As an entertainment, Winter Hall should be an unusual diversion for video game fans more used to glamorised violence and action drama. Show More Summary

Malaria vaccine target's invasion partner uncovered

(Wellcome Trust Sanger Institute) A team at the Wellcome Trust Sanger Institute has discovered how a promising malarial vaccine target -- the protein RH5 -- helps parasites to invade human red blood cells. Published in Nature Communications,...Show More Summary

Malaria vaccine target's invasion partner uncovered

A team at the Wellcome Trust Sanger Institute has discovered how a promising malarial vaccine target - the protein RH5 - helps parasites to invade human red blood cells. Published today in Nature Communications, the study reveals that...Show More Summary

Genes linked to malaria parasites' ability to persist in the body

The ability of malaria parasites to persist in the body for years is linked to the expression of a set of genes from the pir gene family, scientists from the Francis Crick Institute and the Wellcome Trust Sanger Institute have found. Their results are published today in Nature Microbiology.

Largest genetic study of inflammatory bowel disease provides clues on new drug targets

(Wellcome Trust Sanger Institute) In two studies published today (Jan. 30) in Nature Genetics, researchers from the Wellcome Trust Sanger Institute and their collaborators have identified a genetic variant that doubles an individual's risk of developing ulcerative colitis, one of the subtypes of a chronic disorder known as Inflammatory Bowel Disease (IBD).

Developing Beyond game development competition offers $500,000 prize pool to European devs

Medical research charity Wellcome Trust is partnering with Epic Games to launch Developing Beyond, a game development competition that gives European developers one year to build a viable game. Competing for a prize pool worth $500,000,...Show More Summary

Genome secrets of elusive human malaria species revealed

The genomes of the two least common species of human malaria parasites are revealed today in Nature by a team of scientists from the Wellcome Trust Sanger Institute and their international collaborators. These sequences will enable improved surveillance and diagnosis of these rarer parasites that still cause more than 10 million malaria cases every year.

Drexel-led study into the impact of urban living on health awarded $12 million grant

(Drexel University) Awarded $12 million by the Wellcome Trust as part of the its new Our Planet, Our Health initiative. The research network led by Drexel's Ana Diez Roux will explore the impact of urbanization and urban policies on the health and environmental sustainability of Latin American cities and how lessons learned there can be applied to cities worldwide.

Study reveals new genetic mechanism driving breast cancer

(Wellcome Trust Sanger Institute) Researchers at the Wellcome Trust Sanger Institute have discovered 'hotspots' of mutations in breast cancer genomes, where mutations thought to be inactive 'passengers' in the genome have now been shown to possibly drive further cancerous changes. Show More Summary

Global partnership launched to prevent epidemics with new vaccines

(Wellcome Trust) A global coalition to create new vaccines for emerging infectious diseases, designed to help give the world an insurance policy against epidemics, launches today at the World Economic Forum in Davos, Switzerland.

New global coalition launched to create vaccines, prevent epidemics

3 months agoHealth : The Checkup

The effort's initial targets are three viruses. Funding comes from Gates Foundation, Wellcome Trust and the governments of Germany, Japan and Norway.

Best treatment option written in cancer's genetic script

(Wellcome Trust Sanger Institute) An international collaboration led by clinical researchers at the Wellcome Trust Sanger Institute has shown proof-of-concept that truly personalized therapy will be possible in the future for people with cancer. Show More Summary

New genes identified that regulate the spread of cancers

(Wellcome Trust Sanger Institute) Research led by the Wellcome Trust Sanger Institute has discovered a new biological target for drugs to reduce the spread of tumours in cancer patients. Published in Nature today, the study with genetically modified mice found 23 genes that are involved in regulating the spread of cancers. Show More Summary

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