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Plague game up for health trust prize

Winter Hall in the running as Wellcome Trust announces six finalists for its Developing Beyond prize As an entertainment, Winter Hall should be an unusual diversion for video game fans more used to glamorised violence and action drama. Show More Summary

Malaria vaccine target's invasion partner uncovered

(Wellcome Trust Sanger Institute) A team at the Wellcome Trust Sanger Institute has discovered how a promising malarial vaccine target -- the protein RH5 -- helps parasites to invade human red blood cells. Published in Nature Communications,...Show More Summary

Malaria vaccine target's invasion partner uncovered

A team at the Wellcome Trust Sanger Institute has discovered how a promising malarial vaccine target - the protein RH5 - helps parasites to invade human red blood cells. Published today in Nature Communications, the study reveals that...Show More Summary

Genes linked to malaria parasites' ability to persist in the body

The ability of malaria parasites to persist in the body for years is linked to the expression of a set of genes from the pir gene family, scientists from the Francis Crick Institute and the Wellcome Trust Sanger Institute have found. Their results are published today in Nature Microbiology.

Largest genetic study of inflammatory bowel disease provides clues on new drug targets

(Wellcome Trust Sanger Institute) In two studies published today (Jan. 30) in Nature Genetics, researchers from the Wellcome Trust Sanger Institute and their collaborators have identified a genetic variant that doubles an individual's risk of developing ulcerative colitis, one of the subtypes of a chronic disorder known as Inflammatory Bowel Disease (IBD).

Developing Beyond game development competition offers $500,000 prize pool to European devs

Medical research charity Wellcome Trust is partnering with Epic Games to launch Developing Beyond, a game development competition that gives European developers one year to build a viable game. Competing for a prize pool worth $500,000,...Show More Summary

Genome secrets of elusive human malaria species revealed

The genomes of the two least common species of human malaria parasites are revealed today in Nature by a team of scientists from the Wellcome Trust Sanger Institute and their international collaborators. These sequences will enable improved surveillance and diagnosis of these rarer parasites that still cause more than 10 million malaria cases every year.

Drexel-led study into the impact of urban living on health awarded $12 million grant

(Drexel University) Awarded $12 million by the Wellcome Trust as part of the its new Our Planet, Our Health initiative. The research network led by Drexel's Ana Diez Roux will explore the impact of urbanization and urban policies on the health and environmental sustainability of Latin American cities and how lessons learned there can be applied to cities worldwide.

Study reveals new genetic mechanism driving breast cancer

(Wellcome Trust Sanger Institute) Researchers at the Wellcome Trust Sanger Institute have discovered 'hotspots' of mutations in breast cancer genomes, where mutations thought to be inactive 'passengers' in the genome have now been shown to possibly drive further cancerous changes. Show More Summary

Global partnership launched to prevent epidemics with new vaccines

(Wellcome Trust) A global coalition to create new vaccines for emerging infectious diseases, designed to help give the world an insurance policy against epidemics, launches today at the World Economic Forum in Davos, Switzerland.

New global coalition launched to create vaccines, prevent epidemics

last monthHealth : The Checkup

The effort's initial targets are three viruses. Funding comes from Gates Foundation, Wellcome Trust and the governments of Germany, Japan and Norway.

Best treatment option written in cancer's genetic script

(Wellcome Trust Sanger Institute) An international collaboration led by clinical researchers at the Wellcome Trust Sanger Institute has shown proof-of-concept that truly personalized therapy will be possible in the future for people with cancer. Show More Summary

New genes identified that regulate the spread of cancers

(Wellcome Trust Sanger Institute) Research led by the Wellcome Trust Sanger Institute has discovered a new biological target for drugs to reduce the spread of tumours in cancer patients. Published in Nature today, the study with genetically modified mice found 23 genes that are involved in regulating the spread of cancers. Show More Summary

Online epidemic tracking tool embraces open data and collective intelligence

(Wellcome Trust Sanger Institute) Researchers from the Wellcome Trust Sanger Institute and Imperial College London have developed Microreact, a free, real-time epidemic visualization and tracking platform that has been used to monitor outbreaks of Ebola, Zika and antibiotic-resistant microbes. Show More Summary

Enhanced CRISPR lets scientists explore all steps of health and disease in every cell type

(Wellcome Trust Sanger Institute) Today, in the journal Development, scientists describe how a freely available single-step system works in every cell in the body and at every stage of development. This new approach will aid researchers in developmental biology, tissue regeneration and cancer.

Enhanced CRISPR lets scientists explore all steps of health and disease in every cell type

Wellcome Trust Sanger Institute and University of Cambridge researchers have created sOPTiKO, a more efficient and controllable CRISPR genome editing platform. Today, in the journal Development, they describe how the freely available single-step system works in every cell in the body and at every stage of development. Show More Summary

Smoking a pack a day for a year causes 150 mutations in lung cells

(Wellcome Trust Sanger Institute) Scientists have measured the catastrophic genetic damage caused by smoking in different organs of the body and identified several different mechanisms by which tobacco smoking causes mutations in DNA. Show More Summary

Center of gravity for African research funding shifts closer to Africa

(Wellcome Trust) The Wellcome Trust is shifting the center of gravity of its funding for African science from the UK to the continent itself by handing over two major research programs to the African Academy of Sciences' Alliance for Accelerating Excellence in Science in Africa (AAS-AESA).

Vulnerabilities of leukemia cells revealed using genome editing technique

(Wellcome Trust Sanger Institute) Researchers from the Wellcome Trust Sanger Institute and their collaborators have adapted a CRISPR gene editing technique and used it to find new therapeutic targets for acute myeloid leukemia (AML)....Show More Summary

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