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Huge genetic diversity among Papuan New Guinean peoples revealed

The first large-scale genetic study of people in Papua New Guinea has shown that different groups within the country are genetically highly different from each other. Scientists at the Wellcome Trust Sanger Institute and their colleagues...Show More Summary

Immunotherapy treatment option for selected breast cancer patients, genetic study suggests

(Wellcome Trust Sanger Institute) Immunotherapy drugs could help some breast cancer patients based on the genetic changes in their tumors, researchers at the Wellcome Trust Sanger Institute and their collaborators find. Published today in Cancer Research, scientists identify particular genetic changes in a DNA repair mechanism in breast cancer. Show More Summary

Type 2 diabetes is being misdiagnosed in African-Americans, genetic study suggests

One of the tests used to diagnose type 2 diabetes and monitor blood sugar control is influenced by 60 genetic variants, an international team of scientists, including those from the Wellcome Trust Sanger Institute, has found. One genetic...Show More Summary

20,000 international voices share how they want their DNA information used

(Wellcome Trust Sanger Institute) The Wellcome Genome Campus and Global Alliance for Genomics and Health (GA4GH) have gone global with a project to explore public attitudes and beliefs on the sharing of genetic information. Now available...Show More Summary

Bowel cancer study reveals impact of mutations on protein networks

(Wellcome Trust Sanger Institute) For the first time, scientists have completed a detailed study of many of the proteins in bowel cancer cells. Scientists from the Wellcome Trust Sanger Institute investigated the role proteins play in...Show More Summary

New study reveals late spread of breast cancer and backs key role of early diagnosis

(Wellcome Trust Sanger Institute) Breast cancer cells that spread to other parts of the body break off and leave the primary tumor at late stages of disease development, scientists from the Wellcome Trust Sanger Institute and their collaborators have found. Show More Summary

Present-day Lebanese descend from Biblical Canaanites, genetic study suggests

In the most recent whole-genome study of ancient remains from the Near East, Wellcome Trust Sanger Institute scientists and their collaborators sequenced the entire genomes of 4,000-year-old Canaanite individuals who inhabited the region during the Bronze Age, and compared these to other ancient and present-day populations. Show More Summary

CARB-X funding for global scientists racing to discover new antibiotics to treat superbugs

(Wellcome Trust) CARB-X partnership announces funding for global scientists racing to discover new antibiotics. Scientists in India, Ireland, France, Switzerland, the US and UK are to share up to US$17.6m to speed treatments drug-resistant infections. Show More Summary

'Superbugs' study reveals complex picture of E. coli bloodstream infections

(Wellcome Trust Sanger Institute) The first large-scale genetic study of Escherichia coli (E. coli) cultured from patients with bloodstream infections in England showed that drug resistant 'superbugs' don't always out-compete other strains. Show More Summary

Largest study of malaria gene function reveals many potential drug targets

The malaria parasite's success is owed to the stripping down of its genome to the bare essential genes, scientists at the Wellcome Trust Sanger Institute and their collaborators have found. In the first ever large-scale study of malaria...Show More Summary

Existing drugs could benefit patients with bone cancer, genetic study suggests

(Wellcome Trust Sanger Institute) A subgroup of patients with osteosarcoma -- a form of bone cancer -- could be helped by an existing drug, suggest scientists from the Wellcome Trust Sanger Institute and their collaborators. In the largest...Show More Summary

New insights into how the Zika virus causes microcephaly

(Wellcome Trust) Scientists have uncovered why Zika virus may specifically target neural stem cells in the developing brain, potentially leading to microcephaly.

Isolated Greek villages reveal genetic secrets that protect against heart disease

(Wellcome Trust Sanger Institute) A genetic variant that protects the heart against cardiovascular disease has been discovered by researchers at the Wellcome Trust Sanger Institute and their collaborators. Reported today in Nature Communications,...Show More Summary

41 scientists selected by philanthropies as International Research Scholars

(Howard Hughes Medical Institute) HHMI, the Bill & Melinda Gates Foundation, the Wellcome Trust, and the Calouste Gulbenkian Foundation announce the selection of 41 International Research Scholars, early-career scientists poised to advance biomedical research across the globe.

New eye test detects earliest signs of glaucoma

(Wellcome Trust) Researchers at University College London (UCL) and the Western Eye Hospital have developed a simple, inexpensive diagnostic tool DARC (Detection of Apoptosing Retinal Cells). In clinical trials it allowed for the first time visualization of individual nerve cell death in patients with glaucoma. Show More Summary

A unique sense of smell

5 months agoBeauty / Perfume : Now Smell This

Researchers from the Wellcome Trust Sanger Institute and their collaborators have shown that receptors in the noses of mice exposed to certain smells during life are different to genetically similar mice that lived without those smells. Published today in eLife, the study found it is this combination of genetics and experience that gives each individual […]

New chlamydia drug targets discovered using CRISPR and stem cells

(Wellcome Trust Sanger Institute) Scientists at the Wellcome Trust Sanger Institute and their collaborators at the University of British Columbia have created an innovative technique for studying how chlamydia interacts with the human immune system. The results, reported today (April 25) in Nature Communications, identify novel drug targets for the sexually transmitted disease.

Genetics and environment combine to give everyone a unique sense of smell

(Wellcome Trust Sanger Institute) Researchers from the Wellcome Trust Sanger Institute and their collaborators have shown that receptors in the noses of mice exposed to certain smells during life are different to genetically similar mice that lived without those smells. Show More Summary

European Commission May Join Gates Foundation And Wellcome Trust In Becoming An Open Access Publisher

6 months agoIndustries / Law : Techdirt

Open access isn't a new idea -- the term was first defined back in 2002, and arguably the first examples go back even further to the founding of arXiv.org in 1991 (pdf). And yet progress towards making all academic knowledge freely available...Show More Summary

New stem cell method produces millions of human brain and muscle cells in days

(Wellcome Trust Sanger Institute) Wellcome Trust Sanger Institute scientists and their collaborators at the University of Cambridge have created a new technique that simplifies the production of human brain and muscle cells -- allowing millions of functional cells to be generated in just a few days. Show More Summary

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